👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

FanDuel, DraftKings CFB DFS Picks: Daily Fantasy College Football Advice for 9/21/19 (Early Slate)

Week 4 college football DFS lineups, sleepers and value picks for the early slate on FanDuel and DraftKings on September 21st. Target these NCAA players in CFB daily fantasy tournaments and cash games.

Welcome to Week 4 of the college football season! After three extremely fun weeks of football, this fourth week is looking like the best one yet. FanDuel and DraftKings have given us very different slates and while we'll be focusing on DraftKings, I'll do my best to throw in some FanDuel plays as well.

It's certainly a fun slate and we have plenty to dive into. I think QB may be as cut and dry as we've seen to this point, but there's plenty of other spots to get weird and different in tournaments. Let's dive in!

In this article, I will be providing you with my daily fantasy college football lineup picks for the early slate of games on FanDuel and DraftKings on 9/21/19. The lineup picks will range from some of the elite players to mid-priced options and value plays.

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

It's an extremely fun slate ahead of us, with more than enough offense to go around. I'll be breaking down the later slate in a different article, so make sure to keep an eye out for that as well. Let's dive into some of the top plays at each position. You can follow me on Twitter @VarneyDFS. I will be around all day to answer questions.

 

FanDuel, DraftKings DFS Quarterbacks

Joe Burrow - LSU - FD $10,200 DK $8,500

With a 62 point over/under and LSU favored by 24, we can expect at least 40 out of the Tigers here. Vanderbilt has been absolutely terrible against the pass, allowing Elijah Sindelar to throw for 504 yards in their last game. Joe Burrow will continue climbing the Heisman ladder and I could see him throwing for five touchdowns with ease. If Orgeron doesn’t let off the peddle or if Vandy can muster together a couple scores, Burrow could throw for even more. He has three deadly weapons on the outside and an extremely efficient offense. Burrow is the easy cash game morning QB. 

Kelly Bryant - Missouri - FD $9,300 DK $7,500

Missouri is a nine-point favorite at home against South Carolina, who was just pummeled by Alabama. It’s not fair to judge a team by their performance against Bama, but the line more so has to do with Jake Bentley remaining out and the Gamecocks defense struggling. Kelly Bryant hasn’t been needed much in the last two weeks, but he showed what he’s capable of in week one. The hype has cooled back down and we’ll be able to get him for under 10% like we did in the opening slate. I expect this game to be close and South Carolina is a lot better against the run than they are the pass. Bryant is a dual-threat option with a ton of GPP upside. 

Also Consider - Kellen Mond (TAMU), Dillon Gabriel (UCF)

 

FanDuel, DraftKings DFS Running Backs

Cam Akers - FSU - FD $9,800 DK $7,800

Akers has been a volume hog for FSU, and you can expect him to keep eating this week. Excluding a tough week one match-up against Virginia, Akers has 58 touches in two games for 376 yards and four touchdowns. It doesn’t get any tougher this week, as FSU hosts a cupcake Louisville defense that’s given up 100 yards to the only offense that tested them. Akers gets involved through the air as well, so the floor and ceiling are just so high. In cash games, Akers is the highest priced back I’m paying for. 

Lamical Perine - UF - FD $8,800 DK $6,500

We got Ty’Son Williams a couple weeks ago for 1% owned against the Tennessee defense and it brought me to the top of a few tournaments. I doubt Perine is less than 10% here, but he’s a great play nonetheless. Malik Davis hasn’t been involved all that much and Perine has been getting all of the red zone work. Tennessee ranked in the bottom 10 of the entire nation last season against the run and they haven’t gotten off to any better of a start. Florida is still figuring out the QB situation with listed co-starters, so expect them to establish the run game early and often. Perine is a lock for a score. 

Greg McRae - UCF - FD $7,900 DK $6,100 

UCF is a solid 12-point favorite, meaning the game script sets up perfectly for these running backs. I don’t have much of a preference between Killins Jr. and McRae, but McRae is cheaper and has been getting a few more carries. I do expect a fair share of points to be scored through the air in this one, but the running game is something UCF never forgets about. McRae is too cheap on both sites and an excellent play in both formats. 

Also Consider - Isaiah Spiller (TAMU), John Emery Jr. (LSU), Jonathan Taylor (WISC)

 

FanDuel, DraftKings DFS Wide Receivers

Justin Jefferson - LSU - FD $10,000 DK $7,600

This LSU WR trio is extremely talented and you really can’t go wrong. Justin Jefferson and Terrace Marshall Jr. are the two top guys and both should have great games. If I’m picking between the two, I still think Justin Jefferson is the number one option and will end up having the best season. We already touched on this Vanderbilt pass defense that looked anemic against Purdue just a week ago. Jefferson is expensive on both sites, but I’m willing to pay up as I think 150 yards and a touchdown isn’t unlikely. 

Darrell Stewart Jr. - Michigan State - FD $8,600 DK $6,300

I know the total isn’t great in this game, but I really don’t care at this point. Until I see Brian Lewerke throw the ball to anyone else, Darrell Stewart Jr. has 25 catches through three weeks, with Cody White second at 12. This Northwestern defense is a good one, but it mostly relies on the pace of their offense. Michigan State will shut them down and the Northwestern defense will get worn down. Stewart Jr. will get leaned on heavily and you can expect another 8-10 catches and 15 targets. 

Bryan Edwards - South Carolina - FD $7,400 DK $6,300

While I talked down a bit on South Carolina, Ryan Hilinski did fill in last week and threw for over 300 yards against Alabama. A lot of it had to do with playing from behind and throwing the ball every time, but you will still see plenty of guys fail to eclipse 200 yards - even in a blowout. Hilinski and South Carolina now draw a Missouri defense that’s far from scary and as a nine-point underdog, they should be throwing a lot. If we’re expecting another 250+ yards out of Hilinski, Bryan Edwards is too cheap. He’s going to see double digit target and he has as much talent as any of these corners. I’m hoping Edwards flies under the radar here. 

Also Consider - Jerry Jeudy (BAMA), Aaron Fuller (UW), Tamorrion Terry (FSU)

More DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Kirk Cousins

an Option for Rams as Backup Quarterback?
George Pickens

Cowboys Not Worried About George Pickens' Offseason Participation
Dalton Kincaid

Bills Pick Up Dalton Kincaid's Fifth-Year Option
Max Homa

Looks to Get Back on Track at Valero Texas Open
Russell Henley

Continues Blistering Start to 2026 Season
Tommy Fleetwood

Returns to Valero Texas Open
Daniel Berger

Returns to Action For Valero Texas Open
Chase Elliott

Takes Advantage of Pit Strategies for Second Career Martinsville Win
Denny Hamlin

Dominates but Finishes Second at Martinsville
Joey Logano

Bounces Back with Third-Place Finish at Martinsville
Ty Gibbs

Gains his Fourth Top-Five Finish of the Season at Martinsville
William Byron

Scores Another Top-Five Finish at Martinsville
Christian McCaffrey

49ers Looking to Spell Christian McCaffrey More in 2026?
Brandon Aiyuk

49ers in No Rush on Brandon Aiyuk Situation
Michael Penix Jr.

Falcons Don't Want to Rush Michael Penix Jr.'s Rehab
A.J. Brown

is a "Member" of the Eagles
Jonathon Brooks

Panthers Expect Jonathon Brooks to be Ready for OTAs and Minicamp
Alvin Kamara

Saints Going Through "Offseason Process" With Alvin Kamara
Alec Pierce

Can Alec Pierce Perform Like One of the Highest-Paid Receivers in the League?
Michael Pittman Jr.

a Buy-Low Candidate Following Post-Trade Dip
Rhamondre Stevenson

Should Still See Volume in Shared Backfield
NFL

Skyler Bell Hype Warrants Cautious Optimism
NFL

Chris Brazzell III's Pre-Draft Hype Comes with Volatility
Jack Hughes

Amasses Four Points Against Blackhawks
Viktor Arvidsson

Plays Key Role in Comeback Victory
Lane Hutson

Celebrates New Assists Record Sunday
Adam Fox

Collects Two Points in Sunday's Win
Jake Guentzel

Leads Lightning Offense Sunday
Mathieu Olivier

Exits Early With Upper-Body Injury
Michael Bunting

Suffers Lower-Body Injury Sunday
Aaron Rodgers

Steelers Expect Decision From Aaron Rodgers Before the Draft
Joe Pyfer

Extends His Winning Streak
Israel Adesanya

Loses Fourth Consecutive Fight
Nick Suzuki

Collects Three Points Against Hurricanes
Maycee Barber

Suffers Her First Knockout Loss
Frank Nazar

Scores Twice on Sunday
Alexa Grasso

Scores Highlight-Reel Knockout
Niko Price

Retires After UFC Seattle Loss
Keyonte George

Isaiah Collier Still Out Monday
Michael Chiesa

Victorious In His Retirement Fight
Max Strus

to Sit Out Monday's Game
Jarrett Allen

Won't Play Monday Night
Julian Erosa

Suffers First-Round Knockout Loss
Graham Gano

Giants Releasing Graham Gano
Jaylen Wells

Expected to Miss Rest of Season After Toe Procedure
Lerryan Douglas

Scores First-Round Knockout Win In His UFC Debut
Bub Carrington

Exits Early Sunday Due to Cramping
Will Richard

Won't Suit Up Sunday
Seth Curry

Active Against Nuggets
Quinten Post

Back in Action Sunday Night
Aaron Gordon

Won't Play Sunday
Trent Williams

49ers Making Headway With Trent Williams on Potential Extension
Mykel Williams

Expected to be Back for Training Camp
Nick Bosa

49ers Expect Nick Bosa Back for Training Camp
Myles Garrett

Browns GM Confirms Myles Garrett isn't Being Traded
Quinshon Judkins

Browns Hopeful Quinshon Judkins Will be on the Field "in Some Form" This Spring
Alex Bregman

Clobbers First Two Homers in Sunday's Loss at Wrigley
Tobias Harris

Likely to Sit Out Monday's Game
Yandy Díaz

Yandy Diaz Records Five Hits, Drives in Four in Win Over Cardinals
Ausar Thompson

Uncertain for Monday
Jalen Duren

Unlikely to Play Monday
Trey Murphy III

Out on Sunday
Dejounte Murray

Available Against Rockets
Miles McBride

to See Limited Minutes Sunday
Jaden McDaniels

Won't Play Monday
Anthony Edwards

Listed as Questionable for Monday
Collin Murray-Boyles

Misses Sunday's Action
Brandon Ingram

a Late Scratch on Sunday
RJ Barrett

Good to Go Sunday
Robert Williams III

Ready to Play Sunday
Jeremy Swayman

Remains in Bruins Crease Sunday
TB

Nicholas Paul Available Against Predators
Nikita Kucherov

Remains Out Sunday
Mason Lohrei

Unavailable Sunday
Dmitri Voronkov

Considered Week-to-Week
Artyom Levshunov

Out With Fractured Hand
Sidney Crosby

Practices Fully on Sunday
Kyle Larson

Is Likely to Pay Off for DFS at Martinsville
Christopher Bell

Could Have Another Top-10 Performance At Martinsville
William Byron

Is A Threat to Win Again at Martinsville
Chase Elliott

is A Solid DFS Option for Martinsville Lineups
Chase Briscoe

has Plenty of Upside for DFS Lineups at Martinsville
Carlos Estévez

Carlos Estevez Unlikely to See High-Leverage Opportunities in Near Future
Jacob deGrom

Feels "Much Better," Hopeful he Can Start This Week
Cole Hutson

Delivers Two Assists Saturday
Mikhail Sergachev

Ties Mammoth Record With Four Assists
Connor McDavid

Reclaims Scoring Lead With Three-Point Effort
Dmitri Voronkov

Unavailable Sunday
Aliaksei Protas

Suffers Upper-Body Injury Saturday Night
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Martinsville?
Ryan Preece

Is A Solid DFS Option for Martinsville Lineups
Josh Berry

Could Josh Berry Pay Off for Tournament DFS Lineups At Martinsville?
Carson Hocevar

May be Too Inconsistent to Start in Martinsville DFS Lineups
Austin Cindric

Is Austin Cindric Worth Rostering for DFS At Martinsville?
Denny Hamlin

the Favorite to Win at Martinsville
Ryan Blaney

Should Contend at Martinsville
Tyler Reddick

Should Come Back Down to Earth at Martinsville
Joey Logano

Will Be Strong at Martinsville
NASCAR

Bubba Wallace Looking to Rebound at Martinsville
Shane Van Gisbergen

Shane van Gisbergen Showing Progress, Qualifies Fifth at Martinsville
Dylan Cease

Fans 12 in Blue Jays Debut on Saturday
Andrew Vaughn

Needs Hand Surgery, Expected to be Out 4-6 Weeks
Jacob deGrom

"Confident" he Will Make his Next Start
Jacob deGrom

Scratched From Saturday's Start Due to Neck Stiffness
Jeferson Quero

Brewers Calling Up Catching Prospect Jeferson Quero
Deyvison De Los Santos

Marlins Promote Deyvison De Los Santos to Major Leagues
Shea Langeliers

Hits Two Home Runs on Opening Day
Kevin Gausman

Picks Up No-Decision But Strikes Out 11 on Opening Day
Tanner Bibee

Day-to-Day, Could Make his Next Start
Shane Baz

Orioles Agree to Five-Year Extension
Jeremy Peña

Jeremy Pena Making Season Debut on Friday Against Angels
Tiger Woods

Involved In Rollover Car Crash
Tanner Bibee

Shoulder Issue Not Considered Serious
Joe Pyfer

Set For UFC Seattle Main Event
Israel Adesanya

Returns At UFC Seattle
Maycee Barber

Looks To Extend Her Win Streak To Eight
Alexa Grasso

Looks To Get Back In The Win Column
Dominic Canzone

a Top Pickup After Two-Homer Game
Niko Price

In Dire Need Of Victory
Michael Chiesa

Set For Retirement Fight
Chase DeLauter

Launches Two Home Runs, Emerges as Top Waiver-Wire Target
Lerryan Douglas

Set For His UFC Debut
Julian Erosa

Looks To Bounce Back
Tanner Bibee

Leaves Opening Day Start Early With Shoulder Inflammation
Cristopher Sánchez

Cristopher Sanchez Makes a Statement on Opening Day With 10 Strikeouts
Kevin McGonigle

has Four Hits in Impressive MLB Debut
Ryan Fox

a High-Upside Value in Houston
Marco Penge

a Boom-or-Bust Option in Houston
Aaron Rai

Looks to Bounce Back in Houston
Jason Day

a Volatile Option at the Texas Children's Houston Open
Harris English

Eyes a Bounce-Back at the Texas Children's Houston Open
Ben Griffin

Looks for Turnaround at the Texas Children's Houston Open
Rickie Fowler

Brings Strong Form Into Texas Children's Houston Open
Ryan Gerard

Can Continue Rolling at Texas Children's Houston Open
Pierceson Coody

Bounces Back at Valspar Championship
Rasmus Hojgaard

Trying to Get Back on Track at Texas Children's Houston Open
Michael Thorbjornsen

Playing Well Heading to Texas Children's Houston Open
Harry Hall

Looking for Consistency at Texas Children's Houston Open
Brooks Koepka

Continues Building Momentum
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF