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FanDuel Daily Fantasy Football Lineup Picks (Week 6): NFL DFS Advice

Justin Bales' week six FanDuel lineup picks. Daily fantasy football sleepers, value picks and lineups advice for FanDuel DFS games and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 6 of the NFL season. In this article, I, Justin Bales, will be taking you, the reader, through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. Good luck with your FanDuel DFS lineups!

Editor's Note: If you like FanDuel, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

FanDuel Quarterback - Week 6 DFS Picks

Drew Brees (vs CAR, $8,500)

Drew Brees could go a little under owned this season, as people seem to be focusing more on the Panthers offense than the Saints offense. Brees is always an elite option at home and the Panthers have been an average pass defense this season. Brees has scored 26.94 and 31.42 fantasy points in two home starts, while this game has a 53 point total. The Saints are small underdogs, which means they will be throwing the entire game, and Brees should have no problems hitting value this week.

 

FanDuel Running Backs - Week 6 DFS Picks

Le'Veon Bell (at MIA, $9,300)

Le'Veon Bell is one of the most expensive players on the slate, and for good reason. He's essentially a wide receiver playing running back at this point in the season. He's consistent lining up in the slot, and he has 17 targets through two games. He also has 38 carries in those games, and is truly a workhorse player. He gets a good matchup against the Dolphins where the Steelers are -7 point favorites. They should get an early lead and rely heavily on Le'Veon Bell to run the clock out in the second half. He's an elite option this weekend.

Carlos Hyde (at BUF, $7,300)

Carlos Hyde is a volume runner, and the 49ers have no problem giving him the volume he needs. He's also an elite red zone option, as he has six touchdowns in five weeks this season. He gets somewhat of a tough matchup against the Bills, but they aren't an elite defense by any means. The 49ers are big underdogs, but they are every week, and they have no problem giving Hyde the ball when they are losing. He's also coming off a six reception game, which adds even more value to him as a player. He's a high upside tournament option this week.

 

FanDuel Wide Receivers - Week 6 DFS Picks

Mike Wallace (at NYG, $6,400)

Steve Smith Sr. is dealing with an injury and he likely will not play this week. That will bump Mike Wallace to the top receiver, as can be seen last week when Smith got hurt and Wallace ended the game with 11 targets. The Ravens also fired their offensive coordinator, and replaced him with Marty Mornhinweg. Mornhinweg loves running the ball, but his offenses also always rank in the top of the league in big plays, which is where Wallace is at his best. He'll have a high floor because of his volume, but he also comes with an elite ceiling. He's a great option in all leagues against the Giants secondary.

Cameron Meredith (vs JAC, $5,400)

Meredith will likely be chalk this week, and it would be wise to use him. He's coming off a game in which he had nine receptions for 130 yards and one touchdown on 12 targets. Brian Hoyer recently stated that if teams are going to take away Alshon Jeffery, the Bears will have to beat them in other ways, which suggests Meredith will continue to see the large amount of targets. He's a big player with touchdown potential, and he's too cheap this week. Cash teams should be started with him.

 

FanDuel Tight End - Week 6 DFS Picks

Jimmy Graham (vs ATL, $6,900)

Jimmy Graham struggled early in the season, but he has 12 receptions for 213 yards and one touchdown on 17 targets over his last two games. There was a report that Graham and Russell Wilson have been working out together after practice to establish a rhythm, and it has worked out recently. He gets a good matchup against the Falcons, and the Seahawks should be able to score plenty of points this week. Graham comes with great upside, but he's significantly cheaper than the elite tight ends on the slate. He can safely be used in all leagues.

 

FanDuel Defense - Week 6 DFS Picks

Detroit Lions D/ST (vs LA, $4,500)

The Lions defense and special teams has struggled quite a bit this season, but this is an elite matchup. The Rams have the worst offense in the NFL, and they have struggled to score this season. The Lions haven't looked great, but they are -2.5 favorites in a game set at only 43.5 points. Unfortunately, the Vikings are on bye this week, so we'll have to find a someone else to use. The Lions will allow you to spend more money at other positions, which is never a bad idea when there is a low game total.




REAL-TIME FANTASY NEWS

Trevor Story

Hits the Injured List With Groin Injury
Brandon Aiyuk

a Huge Question Mark for Dynasty Managers
Deebo Samuel Sr.

Now Only a Gadget Player/Kick Returner?
Elic Ayomanor

Offseason Additions Hurt Elic Ayomanor's Dynasty Outlook
Tyler Warren

a Clear Top-Five Dynasty Tight End
Jonathon Brooks

a Dynasty RB to Target Despite Injury History?
Blake Snell

Likely to Need Elbow Surgery
Tyler Allgeier

Currently in a Dynasty Buy Window Amid Rollercoaster Offseason
A.J. Brown

Timing Becoming Key to Acquiring A.J. Brown in Dynasty
Quentin Johnston

Is Quentin Johnston on the Verge of a Dynasty Breakout?
Jahmyr Gibbs

Is Jahmyr Gibbs the Dynasty RB1?
Isaiah Likely

The Long-Called-For Isaiah Likely Breakout Could Finally Arrive in 2026
Duncan Robinson

Nets 14 Points With Four Triples
Cade Cunningham

Contributes 21 Points in Game 6 Win
Jalen Duren

Bounces Back With Double-Double
Anthony Edwards

Finishes Season-Ending Loss With 24 Points
Victor Wembanyama

Tallies 19 Points in Friday's Win
De'Aaron Fox

Highly Effective in Blowout Win
Stephon Castle

Shines in Series-Clincher
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Austin Reaves

Could Command $40M Per Year With New Contract
Jalen Duren

Available to Finish Game 6
Yanic Konan Niederhauser

Not Expected to Be Ready for Start of Next Season
Jalen Williams

Declares Himself Healthy for Conference Finals
Terrence Shannon Jr.

Will Play Friday Night
Kevin Huerter

is Available for Game 6
Duncan Robinson

is Returning for Game 6
Caris LeVert

is Cleared for Game 6 on Friday
OG Anunoby

Practices in Full on Friday
Terrence Shannon Jr.

is Tagged as Questionable for Friday
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Luther Burden III

Does Luther Burden III Have WR1 Dynasty Upside in Chicago?
MarShawn Lloyd

Can MarShawn Lloyd Emerge as a Top Dynasty Handcuff Option?
Emanuel Wilson

Can Emanuel Wilson Carve Out a Consistent Role in Seattle?
Max Fried

Heading to Injured List With Elbow Bone Bruise
Jaylin Noel

Playing-Time Outlook in Houston Remains Unclear
Dylan Sampson

Role in Cleveland Looks Secure Heading into 2026
Kirk Cousins

' Dynasty Value Fading Ahead of First Season in Las Vegas
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
George Holani

Dynasty Outlook Remains Cloudy
Jordan Westburg

to Have Season-Ending Elbow Surgery
Kendre Miller

Quickly Fading From Fantasy Relevance
Keon Coleman

Is Keon Coleman a Hopeless Dynasty Asset?
Marvin Harrison Jr.

a Buy-Low Candidate in Dynasty Formats
Hollywood Brown

a Cut Candidate in Dynasty Leagues?
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
Tarik Skubal

Resumes Playing Catch, Ahead of Schedule?
Karl-Anthony Towns

Making an Impact as Playmaker in Playoffs
Jalen Duren

Determined to Improve
Kevin Huerter

Tagged as Questionable for Game 6 Against Cavaliers
Caris LeVert

Considered Questionable for Friday
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
Pavel Dorofeyev

Enjoys Second Consecutive Multi-Goal Game
Shea Theodore

Records Two Points in Game 6 Win
Mitchell Marner

Scores Special Goal in Series-Clincher
Ryan Johnson

Takes Over as Canucks GM, Sedins Promoted to Co-Presidents
Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Quinn Hughes

Finishes Postseason With 15 Points
Matt Boldy

Posts Two Assists in Season-Ending Loss
Scott Wedgewood

Perfect in Relief Effort
Martin Necas

Records Another Multi-Point Game
Brett Kulak

Sends Avalanche Into Conference Finals
Brayden McNabb

Suspended for One Game
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
Juan Soto

Exits Wednesday's Game Early with Ankle Injury
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF