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FanDuel Daily Fantasy Football Lineup Picks (Week 6): NFL DFS Advice

Justin Bales' week six FanDuel lineup picks. Daily fantasy football sleepers, value picks and lineups advice for FanDuel DFS games and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 6 of the NFL season. In this article, I, Justin Bales, will be taking you, the reader, through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. Good luck with your FanDuel DFS lineups!

Editor's Note: If you like FanDuel, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

FanDuel Quarterback - Week 6 DFS Picks

Drew Brees (vs CAR, $8,500)

Drew Brees could go a little under owned this season, as people seem to be focusing more on the Panthers offense than the Saints offense. Brees is always an elite option at home and the Panthers have been an average pass defense this season. Brees has scored 26.94 and 31.42 fantasy points in two home starts, while this game has a 53 point total. The Saints are small underdogs, which means they will be throwing the entire game, and Brees should have no problems hitting value this week.

 

FanDuel Running Backs - Week 6 DFS Picks

Le'Veon Bell (at MIA, $9,300)

Le'Veon Bell is one of the most expensive players on the slate, and for good reason. He's essentially a wide receiver playing running back at this point in the season. He's consistent lining up in the slot, and he has 17 targets through two games. He also has 38 carries in those games, and is truly a workhorse player. He gets a good matchup against the Dolphins where the Steelers are -7 point favorites. They should get an early lead and rely heavily on Le'Veon Bell to run the clock out in the second half. He's an elite option this weekend.

Carlos Hyde (at BUF, $7,300)

Carlos Hyde is a volume runner, and the 49ers have no problem giving him the volume he needs. He's also an elite red zone option, as he has six touchdowns in five weeks this season. He gets somewhat of a tough matchup against the Bills, but they aren't an elite defense by any means. The 49ers are big underdogs, but they are every week, and they have no problem giving Hyde the ball when they are losing. He's also coming off a six reception game, which adds even more value to him as a player. He's a high upside tournament option this week.

 

FanDuel Wide Receivers - Week 6 DFS Picks

Mike Wallace (at NYG, $6,400)

Steve Smith Sr. is dealing with an injury and he likely will not play this week. That will bump Mike Wallace to the top receiver, as can be seen last week when Smith got hurt and Wallace ended the game with 11 targets. The Ravens also fired their offensive coordinator, and replaced him with Marty Mornhinweg. Mornhinweg loves running the ball, but his offenses also always rank in the top of the league in big plays, which is where Wallace is at his best. He'll have a high floor because of his volume, but he also comes with an elite ceiling. He's a great option in all leagues against the Giants secondary.

Cameron Meredith (vs JAC, $5,400)

Meredith will likely be chalk this week, and it would be wise to use him. He's coming off a game in which he had nine receptions for 130 yards and one touchdown on 12 targets. Brian Hoyer recently stated that if teams are going to take away Alshon Jeffery, the Bears will have to beat them in other ways, which suggests Meredith will continue to see the large amount of targets. He's a big player with touchdown potential, and he's too cheap this week. Cash teams should be started with him.

 

FanDuel Tight End - Week 6 DFS Picks

Jimmy Graham (vs ATL, $6,900)

Jimmy Graham struggled early in the season, but he has 12 receptions for 213 yards and one touchdown on 17 targets over his last two games. There was a report that Graham and Russell Wilson have been working out together after practice to establish a rhythm, and it has worked out recently. He gets a good matchup against the Falcons, and the Seahawks should be able to score plenty of points this week. Graham comes with great upside, but he's significantly cheaper than the elite tight ends on the slate. He can safely be used in all leagues.

 

FanDuel Defense - Week 6 DFS Picks

Detroit Lions D/ST (vs LA, $4,500)

The Lions defense and special teams has struggled quite a bit this season, but this is an elite matchup. The Rams have the worst offense in the NFL, and they have struggled to score this season. The Lions haven't looked great, but they are -2.5 favorites in a game set at only 43.5 points. Unfortunately, the Vikings are on bye this week, so we'll have to find a someone else to use. The Lions will allow you to spend more money at other positions, which is never a bad idea when there is a low game total.




REAL-TIME FANTASY NEWS

Keegan Bradley

Looking to Rebound at Colonial
Tory Horton

Could Do Some Stuff "Toward the End of Spring"
Patrick Mahomes

Takes Part in First OTA Practice on Tuesday
Los Angeles Chargers

Derwin James Jr. Becomes Highest-Paid Safety for the Second Time in his Career
Chris Brooks

Emerging as Top Handcuff to Stash?
MarShawn Lloyd

Sees Short-Term Value Soar
Jared McCain

Moves into Starting Five
Boston Celtics

Joe Mazzulla Wins Coach of the Year
Jalen Williams

is Ruled Out for Game 5 on Tuesday
Bucky Irving

is Expected to be Ready for Training Camp
Zion Williamson

to See More Versatile Role
Parker Washington

Jaguars Think Parker Washington Can Replicate Second-Half Production
Cleveland Cavaliers

Kenny Atkinson to Remain Cavaliers Head Coach Next Season
Josh Jacobs

Arrested on Five Charges, Booked Into Jail
Claude Giroux

Planning to Return for 20th NHL Campaign
Josh Sweat

Cardinals Receiving Trade Calls on Josh Sweat
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Tetairoa McMillan

Working With the Training Staff on Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
Nathan MacKinnon

Will Suit Up Tuesday
Jerome Ford

Is it Time for Dynasty Managers to Drop Jerome Ford?
John Metchie III

Poised for Breakout Season with New Team in 2026?
Jalen Milroe

Is Jalen Milroe Still Worth Stashing in Dynasty Formats Entering 2026?
Kyle Pitts Sr.

Is Kyle Pitts Sr. a Dynasty Sell-High Candidate Coming Off Breakout Season?
Nico Collins

Agrees to Contract Adjustment with Texans
Chris Brooks

Carries Buy-Low Dynasty Appeal into 2026
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
NFL

NFL Unlikely to Expand to 18 Regular-Season Games by 2027
Sahith Theegala

Searching For Swing at Charles Schwab Challenge
Lamar Jackson

in Attendance at OTAs This Week
Bucky Irving

Expected Back in the Summer or Fall
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
Jalen Tolbert

Does Jalen Tolbert Have Short-Term Dynasty Appeal?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Travis Etienne Jr.

Is Travis Etienne Jr. Still a Dynasty RB1 Following Change of Scenery?
Evan Mobley

Finishes Season-Ending Loss With 15 Points
James Harden

Wants to Stay in Cleveland
Donovan Mitchell

Remains Committed to Cavaliers
Mikal Bridges

Cools Off in Game 4 Against Cavaliers
OG Anunoby

Active on Both Ends in Blowout Win
Karl-Anthony Towns

Leads Knicks in Scoring During Series-Clincher
Jalen Brunson

Named Eastern Conference Finals MVP
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
Shayne Gostisbehere

Scores First Postseason Goal
Taylor Hall

Ends Four-Game Goal Drought
Andrei Svechnikov

Scores Game 3 Winner in Overtime
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dennis Schröder

Dennis Schroder is Ruled Out for Game 4 on Monday
Michael Porter Jr.

Nets Could Trade Michael Porter Jr.
Ajay Mitchell

is Ruled Out for Game 5
Jalen Williams

is Tagged as Questionable for Game 5
Valeri Nichushkin

Nathan MacKinnon, Valeri Nichushkin Uncertain for Game 4
Oliver Kapanen

Sitting as Healthy Scratch Monday
Max Domi

Out Indefinitely Due to Offseason Surgery Complications
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Devon Toews

Logs Two Assists In Game 3 Defeat
Brett Howden

Nets 10th Postseason Goal
Mitchell Marner

Delivers Two Assists in Comeback Victory
Mark Stone

Returns With Multi-Point Effort
Valeri Nichushkin

Exits Early Sunday
Nathan MacKinnon

Hurt in Game 3 Loss
Isaiah Hartenstein

Provides Steady Production in Defeat
Chet Holmgren

Has a Quiet Offensive Night on Sunday
Shai Gilgeous-Alexander

Held Under 20 Points in Game 4
Stephon Castle

Hands Out Six Assists in Game 4 Win
Devin Vassell

Tallies 13 Points in Game 4 Win
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Robby Snelling

Will Undergo Tommy John Surgery
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF