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FanDuel Daily Fantasy Football Lineup Picks (Week 6): NFL DFS Advice

Justin Bales' week six FanDuel lineup picks. Daily fantasy football sleepers, value picks and lineups advice for FanDuel DFS games and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 6 of the NFL season. In this article, I, Justin Bales, will be taking you, the reader, through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. Good luck with your FanDuel DFS lineups!

Editor's Note: If you like FanDuel, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

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FanDuel Quarterback - Week 6 DFS Picks

Drew Brees (vs CAR, $8,500)

Drew Brees could go a little under owned this season, as people seem to be focusing more on the Panthers offense than the Saints offense. Brees is always an elite option at home and the Panthers have been an average pass defense this season. Brees has scored 26.94 and 31.42 fantasy points in two home starts, while this game has a 53 point total. The Saints are small underdogs, which means they will be throwing the entire game, and Brees should have no problems hitting value this week.

 

FanDuel Running Backs - Week 6 DFS Picks

Le'Veon Bell (at MIA, $9,300)

Le'Veon Bell is one of the most expensive players on the slate, and for good reason. He's essentially a wide receiver playing running back at this point in the season. He's consistent lining up in the slot, and he has 17 targets through two games. He also has 38 carries in those games, and is truly a workhorse player. He gets a good matchup against the Dolphins where the Steelers are -7 point favorites. They should get an early lead and rely heavily on Le'Veon Bell to run the clock out in the second half. He's an elite option this weekend.

Carlos Hyde (at BUF, $7,300)

Carlos Hyde is a volume runner, and the 49ers have no problem giving him the volume he needs. He's also an elite red zone option, as he has six touchdowns in five weeks this season. He gets somewhat of a tough matchup against the Bills, but they aren't an elite defense by any means. The 49ers are big underdogs, but they are every week, and they have no problem giving Hyde the ball when they are losing. He's also coming off a six reception game, which adds even more value to him as a player. He's a high upside tournament option this week.

 

FanDuel Wide Receivers - Week 6 DFS Picks

Mike Wallace (at NYG, $6,400)

Steve Smith Sr. is dealing with an injury and he likely will not play this week. That will bump Mike Wallace to the top receiver, as can be seen last week when Smith got hurt and Wallace ended the game with 11 targets. The Ravens also fired their offensive coordinator, and replaced him with Marty Mornhinweg. Mornhinweg loves running the ball, but his offenses also always rank in the top of the league in big plays, which is where Wallace is at his best. He'll have a high floor because of his volume, but he also comes with an elite ceiling. He's a great option in all leagues against the Giants secondary.

Cameron Meredith (vs JAC, $5,400)

Meredith will likely be chalk this week, and it would be wise to use him. He's coming off a game in which he had nine receptions for 130 yards and one touchdown on 12 targets. Brian Hoyer recently stated that if teams are going to take away Alshon Jeffery, the Bears will have to beat them in other ways, which suggests Meredith will continue to see the large amount of targets. He's a big player with touchdown potential, and he's too cheap this week. Cash teams should be started with him.

 

FanDuel Tight End - Week 6 DFS Picks

Jimmy Graham (vs ATL, $6,900)

Jimmy Graham struggled early in the season, but he has 12 receptions for 213 yards and one touchdown on 17 targets over his last two games. There was a report that Graham and Russell Wilson have been working out together after practice to establish a rhythm, and it has worked out recently. He gets a good matchup against the Falcons, and the Seahawks should be able to score plenty of points this week. Graham comes with great upside, but he's significantly cheaper than the elite tight ends on the slate. He can safely be used in all leagues.

 

FanDuel Defense - Week 6 DFS Picks

Detroit Lions D/ST (vs LA, $4,500)

The Lions defense and special teams has struggled quite a bit this season, but this is an elite matchup. The Rams have the worst offense in the NFL, and they have struggled to score this season. The Lions haven't looked great, but they are -2.5 favorites in a game set at only 43.5 points. Unfortunately, the Vikings are on bye this week, so we'll have to find a someone else to use. The Lions will allow you to spend more money at other positions, which is never a bad idea when there is a low game total.




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REAL-TIME FANTASY NEWS

Victor Hedman

Good to Go for Wednesday
Yordan Alvarez

Not Cleared to Play in Spring Games
Brayden Point

Available for Lightning
Chet Holmgren

Cleared for Action on Tuesday
Mikko Rantanen

to Miss at Least Two Weeks
Anfernee Simons

Suffers Fractured Left Wrist
Draymond Green

Won't Be Limited on Tuesday
Evan Mobley

to Remain Limited on Tuesday
Davion Mitchell

Back in Action Vs. Bucks
Daniel Gafford

Active Tuesday
Dejounte Murray

is Officially Active on Tuesday
Joel Embiid

Back In Lineup Vs. Indiana
Kam Jones

Set To Suit Up Tuesday
Nikola Jović

Nikola Jovic is Ruled Out on Tuesday
Shaedon Sharpe

Sidelined at Least Four More Weeks
Carlos Estévez

Carlos Estevez's Velocity Down in Spring Debut
Pascal Siakam

Out Tuesday, Micah Potter Cleared to Play
Tristan Vukcevic

to Play on Tuesday
Billy Horschel

Looks to Improve Season at Cognizant Classic
T.J. McConnell

Andrew Nembhard, T.J. McConnell Cleared to Play Tuesday
Kyle Pitts Sr.

Falcons Place Franchise Tag on Kyle Pitts Sr.
Jonathan Kuminga

Set to Make Hawks Debut on Tuesday
Ryan Kalkbrenner

Slated to Suit Up Tuesday
Joe Highsmith

Returns to Defend at Cognizant Classic
Quinshon Judkins

Out of Walking Boot, Will be Ready for Training Camp
Vince Williams Jr.

Out for Remainder of Season
Jaxson Hayes

Sidelined on Tuesday
Al Horford

De'Anthony Melton Will Play Against the Pelicans, Al Horford Ruled Out
Naz Reid

Listed as Available to Play Tuesday
Jalen Smith

Will Not Play Tuesday Against the Hornets
Breece Hall

Jets Will Use Franchise Tag on Breece Hall if Extension isn't Reached
Trey Yesavage

to be on Strict Inning Limit This Season
Joel Dahmen

Needs Better Consistency Heading Into The Florida Swing
Blaine Crim

Suffers Oblique Strain
Matt Waldron

"Week-to-Week" After Undergoing Surgery
Daniel Berger

Looks to Improve Putting as PGA Tour Begins Its Florida Swing
Oneil Cruz

Looking to Improve Against Left-Handed Pitchers
Sebastian Walcott

has Internal-Brace Surgery, Out 5-6 Months
Ricky Tiedemann

to Back Off for a Week Due to Elbow Soreness
Kirk Cousins

Falcons Plan to Release Kirk Cousins
Zach Ertz

Plans to Return for 14th Season
Jameson Taillon

Can Be a Sneaky Late-Round Value
Matt Wallner

Ready for a Breakout Season?
Andrés Giménez

Andres Gimenez Looking for Healthy 2026
Ernie Clement

Expected to Play a Major Role in Toronto
Chris Sale

Signs Extension With Braves
Davis Thompson

Struggling to Find Birdies as Florida Looms
Tom Kim

Not Quite Cutting It in 2026
Nicolai Hojgaard

Wants to Build Momentum from Scottsdale
Christiaan Bezuidenhout

Returns After Extended Break for Florida Event
Carson Fulmer

Signs Minor-League Deal With Pirates
Brent Honeywell

Signs Minor-League Contract With Giants
Graham Pauley

Undergoes Imaging for Forearm Tightness
Trevor Story

a Strong Candidate to Hit Second in 2026
Bryan Abreu

Could Begin Season as the Closer
Justin Foscue

Exits Grapefruit League Game With Hamstring Tightness
Trevor Megill

had Offseason PRP Injections
Merrill Kelly

is Awaiting MRI Results
CFB

Gunner Rivers Follows His Father, Commits To North Carolina State
Will Zalatoris

Set to Make Tournament Debut at Cognizant Classic
Linus Ullmark

Available for Senators
Rasmus Hojgaard

Trending Up at the Cognizant Classic
Ryan Reaves

Sharks Activate Ryan Reaves From Injured Reserve
Charlie Lindgren

Activated From Injured Reserve Monday
Josh Norris

Cleared to Return Wednesday
Max McGreevy

Will Need to Improve on the Greens to Compete
Rico Hoey

Returns to Cognizant Classic
Austin Eckroat

Looks to Bounce Back at Cognizant Classic
Aaron Rai

Bounces Back After Rough Start to 2026 Season
Shane Lowry

Continues Playing Well Heading to Cognizant Classic
Max Homa

Has Opportunity to Continue Building Momentum at the Cognizant Classic
Ryan Gerard

Strong Approach Play Behind his Hot Start in 2026
Luke Clanton

Making Fourth Start of 2026 at Cognizant Classic
Kevin Lankinen

Unlikely to Play Wednesday
Josh Morrissey

to Miss Start of Road Trip
Mikko Rantanen

Expected to Miss Time
Andrew Putnam

Looks to Jumpstart His Season at Cognizant Classic
Adam Scott

Looks For Continued Success at PGA National
Anthony Hernandez

Suffers Third-Round TKO Loss
Sean Strickland

Gets Back In The Win Column
Kyle Pitts Sr.

Falcons Planning to Use Franchise Tag on Kyle Pitts Sr.
Geoff Neal

Suffers Back-To-Back Knockout Losses
Uros Medic

Shines At UFC Houston
Dan Ige

Gets Finished For The First Time In His Career
Melquizael Costa

Extends His Win Streak To Six
NASCAR

Bubba Wallace Falls Short of Victory at EchoPark Speedway
Carson Hocevar

Rallies to Fourth At EchoPark Speedway After Early Struggles
Ross Chastain

Finishes Third At EchoPark Speedway
Chase Briscoe

Scores First Career Top-Five Finish at EchoPark Speedway
Tyler Reddick

Nabs His Second Win of the Season At EchoPark Speedway
Joey Logano

Will Be Popular DFS Pick at EchoPark Speedway
Tyler Reddick

on Pole After Qualifying Rained Out at EchoPark Speedway
Chase Elliott

Could Chase Elliott Be Worth Rostering At EchoPark Speedway?
Ryan Blaney

Is Ryan Blaney Worth Rostering for DFS at EchoPark Speedway?
William Byron

Is William Byron Worth Rostering for DFS at EchoPark Speedway?
Rondale Moore

Passes Away
Denny Hamlin

Is Worth Consideration for EchoPark Speedway DFS Lineups
Brad Keselowski

Is A Tournament Option for DFS At EchoPark Speedway
NASCAR

Is Bubba Wallace Rosterable In DFS At EchoPark Speedway?
Austin Cindric

Should DFS Managers Roster Austin Cindric at EchoPark Speedway?
Ross Chastain

Is Ross Chastain A Sneaky DFS Option for EchoPark Speedway?
Ricky Stenhouse Jr

Is Ricky Stenhouse Jr. Worth Rostering for DFS at EchoPark Speedway?
Alex Bowman

Will Start Towards the Rear At EchoPark Speedway
Javonte Williams

Cowboys Sign Javonte Williams to Three-Year, $24 Million Extension
Joel Armia

Wraps Up Olympics With Three-Point Performance
Daniil Tarasov

Available for Panthers
Evan Rodrigues

Set to Return Next Week
Aaron Ekblad

Expected to Play Thursday
Pavel Zacha

Cleared for Action
VAN

Jonathan Lekkerimaki Needs Season-Ending Shoulder Surgery
Mikko Rantanen

Misses Bronze-Medal Game With Lower-Body Injury
Blake Coleman

Activated From Injured Reserve
Matt Rempe

Heading to Injured Reserve After Second Thumb Procedure
Sidney Crosby

a Game-Time Call for Olympic Final
Josh Morrissey

Won't Play Sunday
Travis Etienne Jr.

has "Legitimate Interest" in Joining Chiefs
Zach Charbonnet

Undergoes Knee Surgery on Friday
CFB

Curt Cignetti Agrees to New Deal With Indiana, Will Earn $13.2 Million Per Year
Anthony Hernandez

Set For UFC Houston Main Event
Sean Strickland

Looks To Get Back In The Win Column
Uros Medic

Set For UFC Houston Co-Main Event
Geoff Neal

Looks To Get Back In The Win Column
Melquizael Costa

A Favorite At UFC Houston
Dan Ige

An Underdog At UFC Houston
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