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DraftKings NFL DFS Lineup Picks for Week 5

Welcome to Week 5 of the NFL season. There are tons of contests on both major DFS sites, and this is the time of year to cash in. Below are my DraftKings DFS Lineup Picks for Week 5.

These DraftKings lineup recommendations are based on match ups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 5.

Good luck with your DraftKings DFS lineups!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 5 Picks

Jacoby Brissett - IND vs SF (DK $5,600)

Brissett is coming off a rough week against the Seahawks, but he is in a great spot to bounce back at home. He is up against the 49ers, who have the 26th DVOA against the pass, and have shown they have trouble stopping the deep ball. Brissett is a young QB who has flashed the upside against bad teams, most notably, two weeks ago against the Browns, where he put up 27 DraftKings points. He is a dual threat QB, and can make plenty of plays alone, and always has the potential to run one in. If you like spending down at QB, Brissett is a great option, which will allow you plenty of salary flexibility to fit in a high price running back or receiver.

Aaron Rodgers - GB @ DAL (DK $8,100)

If you want to pay up at quarterback this week, there is no reason to dance around, go with Rodgers. He has 20 or more DraftKings points in every game this season, and will be up against the Cowboys who have the 21st DVOA against the pass. Rodgers gives you consistent multi touchdown upside, along with a shot at the 300 yard bonus every game. This game has an over under of 52.5 points, which is the highest of the remaining games, so we are expecting a shootout. You should 100% pair him with a receiver, so you can double dip on the points, Jordy Nelson and Randall Cobb make great plays.

 

DraftKings DFS Running Backs - Week 5 Picks

Melvin Gordon - LAC @ NYG (DK $6,000)

Gordon didn't have the best game last week vs the Eagles, but he is in a spot to bounce back. He is on the road vs the Giants who have 31st DVOA against the rush, and the 19th DVOA against running backs in the passing game. He is $1K cheaper than he was last week, and has seen 72% of all rushing attempts by the Chargers. He is seemingly going overlooked by some this week, and not sure why. He gets goal line carries, sees work in the passing game, he does it all. Great in any format this week against a lackluster Giants defense.

Andre Ellington - ARI @ PHI (DK $4,600)

Ellington has seen eight or more targets in each of the past two weeks, which has lead to 13 or more DraftKings points over that span. The Cardinals are road dogs in this game, which means, according to Vegas, they will be down. This leads them to passing the ball more, and thus, puts Ellington in a great spot. For his price, he only needs to get 13 points to hit value for a cash game, and that is certainly doable this week. He is up against the Eagles who have the 21st DVOA against running backs in the passing game, making this match up all the more favorable.

 

DraftKings DFS Wide Receivers - Week 5 Picks

Devante Parker - MIA vs TEN (DK $6,600)

Although the the Dolphins have only put up six points in the last two weeks, they are in a spot to bounce back this week. They are up against the Titans who have the 31st DVOA overall, which puts them in a spot to bounce back. Parker has seen eight or more targets in each of the last three weeks, with six plus receptions in two straight weeks. Due to the volume he is seeing, he is viable in both cash and GPP. The Titans' secondary was burned over the past two weeks, by the opposing team's top receiver, and we should see much of the same this week.

Aldrick Robinson - SF @ IND (DK $3,100)

Robinson is in a great spot if Marquise Goodwinis out due to his concussion issues. Robinson is basically minimum salary on DraftKings, which will open up your lineup, so you can fit in two high priced position players. He is up against the Colts, who have the 24th DVOA against the pass, and with both of these defenses being so bad, we could be in for a shootout. Robinson is viable in any format with his cheap price and salary savings.

 

DraftKings DFS Tight Ends - Week 5 Picks

Martellus Bennett - GB @ DAL (DK $4,100)

There was a report that came out earlier in the week, where Aaron Rodgers said he needs to do a better job of getting Bennett involved in the passing game. In a game that has an over under set at 52.5 points, this makes Bennett a very interesting option. They story line sets up for him to be seeing the ball more, in a game which should be a shootout. Bennett has seen six or more targets in three of four games this season, and is up against Dallas who has the 15th DVOA against tight ends.

 

DraftKings DFS Defenses - Week 5 Picks

Pittsburgh Steelers vs Jacksonville Jaguars (DK $3,900)

The Steelers are the highest priced defense on the board this week, but they are at home against a turnover prone Jaguars team. Any time the Jaguars are on the road, and Blake Bortles is behind center, he is prone to turnovers. The Steelers defense has double digit points in two of four games this season, and have four or more sacks in two of four games. They are pressuring the QB, which will lead to rushed throws, something that Bortles struggles with. They are expensive, but clearly the best match up on paper this week.

 

More Week 5 Lineup Prep




REAL-TIME FANTASY NEWS

Kevin Huerter

Active on Sunday Night
Caris LeVert

Duncan Robinson, Caris LeVert Available Sunday
Dean Wade

Max Strus Replaces Dean Wade in Starting Lineup Sunday
Luke Kornet

Iffy for Monday
Larry Nance Jr.

Won't Play Sunday
De'Aaron Fox

Listed as Questionable for Monday's Action
Jalen Williams

Officially Available for Game 1 Against Spurs
Shai Gilgeous-Alexander

Named MVP for Second Straight Year
Jonah Coleman

is an Intriguing Power Back to Target in Dynasty Leagues
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Darius Slayton

Lacking Long-Term Upside for Dynasty Managers
Keaton Mitchell

a Prime Dynasty Handcuff Option Entering First Season in L.A.
Jadarian Price

Looks Like the Running Back of the Future in Seattle
Isaiah Bond

Dynasty Outlook Clouded by Uncertain Role in Cleveland
James Cook III

Remains a High-End Dynasty RB1 Entering 2026
Lamar Jackson

Poised for Bounce Back Season in 2026
Bucky Irving

Expected to Be Ready for Training Camp
Kyle Williams

Deep Threat Kyle Williams Facing Uphill Battle for Playing Time
Michael Pittman Jr.

Could Receive Short-Term Value Uptick in PPR Leagues
Stefon Diggs

Chiefs, Commanders Could Make Sense for Stefon Diggs
Will Howard

Dynasty Value Dealt a Blow
Jaylen Warren

Should Benefit From Veteran QB's Return to Pittsburgh
Drew Allar

Could Continue to Hold Dynasty Value
Pat Freiermuth

Could See a Small Dynasty Bump With Veteran QB Returning
DK Metcalf

A Dynasty Sell Candidate With Veteran QB Returning?
Bones Hyland

Wants to Stay in Minnesota
Mike Conley

Hints He Will Continue Playing Next Season
Kevin Huerter

Iffy for Sunday Night
Caris LeVert

Questionable for Game 7
Duncan Robinson

Back on Injury Report Ahead of Game 7
Larry Nance Jr.

Likely Out Sunday Due to Illness
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Aaron Rodgers

Signs One-Year Deal With Steelers
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Alex Lyon

Likely to Start Game 6 Against Canadiens
Owen Power

Available Saturday
Isaac TeSlaa

Can Isaac TeSlaa Carve Out a Larger Role in Detroit Going Forward?
Troy Franklin

Facing Uphill Battle for Playing Time in Denver
Trevor Lawrence

Should Trevor Lawrence Be Valued as a Dynasty QB1?
Courtland Sutton

in Line for Reduced Role in Denver?
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Duncan Robinson

Nets 14 Points With Four Triples
Cade Cunningham

Contributes 21 Points in Game 6 Win
Jalen Duren

Bounces Back With Double-Double
Anthony Edwards

Finishes Season-Ending Loss With 24 Points
Victor Wembanyama

Tallies 19 Points in Friday's Win
De'Aaron Fox

Highly Effective in Blowout Win
Stephon Castle

Shines in Series-Clincher
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Max Fried

Heading to Injured List With Elbow Bone Bruise
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Jordan Westburg

to Have Season-Ending Elbow Surgery
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
Tarik Skubal

Resumes Playing Catch, Ahead of Schedule?
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
Pavel Dorofeyev

Enjoys Second Consecutive Multi-Goal Game
Shea Theodore

Records Two Points in Game 6 Win
Mitchell Marner

Scores Special Goal in Series-Clincher
Ryan Johnson

Takes Over as Canucks GM, Sedins Promoted to Co-Presidents
Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Quinn Hughes

Finishes Postseason With 15 Points
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
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1B
2B
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SP
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