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DraftKings NFL DFS Lineup Picks for Week 5

Welcome to Week 5 of the NFL season. There are tons of contests on both major DFS sites, and this is the time of year to cash in. Below are my DraftKings DFS Lineup Picks for Week 5.

These DraftKings lineup recommendations are based on match ups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 5.

Good luck with your DraftKings DFS lineups!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 5 Picks

Jacoby Brissett - IND vs SF (DK $5,600)

Brissett is coming off a rough week against the Seahawks, but he is in a great spot to bounce back at home. He is up against the 49ers, who have the 26th DVOA against the pass, and have shown they have trouble stopping the deep ball. Brissett is a young QB who has flashed the upside against bad teams, most notably, two weeks ago against the Browns, where he put up 27 DraftKings points. He is a dual threat QB, and can make plenty of plays alone, and always has the potential to run one in. If you like spending down at QB, Brissett is a great option, which will allow you plenty of salary flexibility to fit in a high price running back or receiver.

Aaron Rodgers - GB @ DAL (DK $8,100)

If you want to pay up at quarterback this week, there is no reason to dance around, go with Rodgers. He has 20 or more DraftKings points in every game this season, and will be up against the Cowboys who have the 21st DVOA against the pass. Rodgers gives you consistent multi touchdown upside, along with a shot at the 300 yard bonus every game. This game has an over under of 52.5 points, which is the highest of the remaining games, so we are expecting a shootout. You should 100% pair him with a receiver, so you can double dip on the points, Jordy Nelson and Randall Cobb make great plays.

 

DraftKings DFS Running Backs - Week 5 Picks

Melvin Gordon - LAC @ NYG (DK $6,000)

Gordon didn't have the best game last week vs the Eagles, but he is in a spot to bounce back. He is on the road vs the Giants who have 31st DVOA against the rush, and the 19th DVOA against running backs in the passing game. He is $1K cheaper than he was last week, and has seen 72% of all rushing attempts by the Chargers. He is seemingly going overlooked by some this week, and not sure why. He gets goal line carries, sees work in the passing game, he does it all. Great in any format this week against a lackluster Giants defense.

Andre Ellington - ARI @ PHI (DK $4,600)

Ellington has seen eight or more targets in each of the past two weeks, which has lead to 13 or more DraftKings points over that span. The Cardinals are road dogs in this game, which means, according to Vegas, they will be down. This leads them to passing the ball more, and thus, puts Ellington in a great spot. For his price, he only needs to get 13 points to hit value for a cash game, and that is certainly doable this week. He is up against the Eagles who have the 21st DVOA against running backs in the passing game, making this match up all the more favorable.

 

DraftKings DFS Wide Receivers - Week 5 Picks

Devante Parker - MIA vs TEN (DK $6,600)

Although the the Dolphins have only put up six points in the last two weeks, they are in a spot to bounce back this week. They are up against the Titans who have the 31st DVOA overall, which puts them in a spot to bounce back. Parker has seen eight or more targets in each of the last three weeks, with six plus receptions in two straight weeks. Due to the volume he is seeing, he is viable in both cash and GPP. The Titans' secondary was burned over the past two weeks, by the opposing team's top receiver, and we should see much of the same this week.

Aldrick Robinson - SF @ IND (DK $3,100)

Robinson is in a great spot if Marquise Goodwinis out due to his concussion issues. Robinson is basically minimum salary on DraftKings, which will open up your lineup, so you can fit in two high priced position players. He is up against the Colts, who have the 24th DVOA against the pass, and with both of these defenses being so bad, we could be in for a shootout. Robinson is viable in any format with his cheap price and salary savings.

 

DraftKings DFS Tight Ends - Week 5 Picks

Martellus Bennett - GB @ DAL (DK $4,100)

There was a report that came out earlier in the week, where Aaron Rodgers said he needs to do a better job of getting Bennett involved in the passing game. In a game that has an over under set at 52.5 points, this makes Bennett a very interesting option. They story line sets up for him to be seeing the ball more, in a game which should be a shootout. Bennett has seen six or more targets in three of four games this season, and is up against Dallas who has the 15th DVOA against tight ends.

 

DraftKings DFS Defenses - Week 5 Picks

Pittsburgh Steelers vs Jacksonville Jaguars (DK $3,900)

The Steelers are the highest priced defense on the board this week, but they are at home against a turnover prone Jaguars team. Any time the Jaguars are on the road, and Blake Bortles is behind center, he is prone to turnovers. The Steelers defense has double digit points in two of four games this season, and have four or more sacks in two of four games. They are pressuring the QB, which will lead to rushed throws, something that Bortles struggles with. They are expensive, but clearly the best match up on paper this week.

 

More Week 5 Lineup Prep




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Unlikely to Play Thursday
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Remains Out Thursday
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Kris Knoblauch Fired as Oilers Head Coach
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Expected to Miss the Early Part of the Season
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Not Set Up for Immediate Success in Miami
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Must Make Gains as Pass-Catcher to Take the Next Step
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Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Kaytron Allen

Could Kaytron Allen Take on a Big Role Right Away?
Demond Claiborne

Has Long-Term Appeal in Minnesota
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Adam Randall

to Contribute as a Pass-Catcher Right Away?
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has Knee Surgery, Expected to Miss Eight Weeks
Nicholas Singleton

Could Contribute Right Away
Bryce Lance

a Perfect Fit in New Orleans?
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Can Mike Washington Jr. Force a Backfield Split in Vegas?
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Tallies 39 Points in Losing Effort
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Close to Triple-Double Wednesday
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Posts Two Assists in Season-Ending Loss
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Perfect in Relief Effort
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Records Another Multi-Point Game
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Sends Avalanche Into Conference Finals
Brayden McNabb

Suspended for One Game
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
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Pulled Early With Possible Leg Injury
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Exits Wednesday's Game Early with Ankle Injury
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is Available for Game 5 on Wednesday
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is Out for Game 5
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Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
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Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
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Set to Miss Second Straight Game
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Notches 17 Points in Game 5 Loss
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Looks to Defend PGA Championship at Aronimink
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Posts a Double-Double in Losing Effort
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
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Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

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Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Victor Wembanyama

Leads Spurs to Big Win in Game 5
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Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

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Leaves Game on Tuesday with Apparent Ankle Injury
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Isaac Brown Has All-American Upside in 2026
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Jaron-Keawe Sagapolutele Has Eyes on ACC Title
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Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
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Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

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Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
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Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
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Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
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Carlos Rodon Activated for Season Debut on Sunday
William Byron

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Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
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A.J. Allmendinger May have Another Solid Outing at Watkins Glen
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Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
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Is Carson Hocevar Too Aggressive for Road-Course Racing?
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF