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DraftKings Lineup Picks (Week 15) - NFL DFS Advice

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 15 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 14!

 

DraftKings Quarterbacks - Week 15 DFS Picks

Matt Ryan - ATL @ TB (DK - $6,300)

Ryan is coming off a very rough three interception game, but now has a very favorable match up in his favor. He is at division rival Tampa Bay, who has the 31st DVOA against the pass, who when he played them earlier this season, he put up over 300 yards and one touchdown. This is a level of production that he should be able to match, considering the Falcons have an implied team total of 27 points, which is third highest on the slate. This game is on Monday night, so you will have to have to play on one of the expanded slates to get to him. Given the match up, he has multi-touchdown upside and a good play for GPPs.

Derek Carr - OAK vs DAL (DK - $5,700)

Carr has scored 14.5 or more DraftKings points in six of his last seven games, and is facing a weak defensive opponent. At his price, he really only needs about 16 DK points in order to reach 3x value for cash games. He is up against the Cowboys, who have the 22nd DVOA against the pass, and have shown they are very weak in the secondary. Carr will be without Amari Cooper, so pairing him with Michael Crabtree is a good idea for either format. Carr along with the Raiders haven't been consistent this season, so some DFS player might be afraid to roster him, opening the chance for lower ownership.

 

DraftKings Running Backs - Week 15 DFS Picks

Dion Lewis - RB, NE @ PIT (DK - $5,400)

Lewis has double digit rushing attempts in seven of his last last eight games, along with 11 targets in his lat four games. This game vs the Steelers has an over-under of 53 points, making it the highest of the slate, so you will want some exposure to this game. He isn't too expensive, and with the snaps he is seeing, he can pay off his salary quickly. The Steelers have the 29th DVOA against running backs in the passing game, which makes this a fantastic match up, considering his PPR value out of the backfield.

LeSean McCoy - RB, BUF vs MIA (DK - $8,400)

McCoy is in line to see plenty of work this week considering the fact the Bills are in a tough spot at quarterback. Seemingly for the past month, the Bills have a rotating cast at quarterbacks, because of injuries. McCoy had 32 carries last week, which is super high, but that was mainly due to the weather. He won't see that type of volume every week, but with Tyrod Taylor on the injury report, he could see close to it. McCoy is up against the Dolphins who have the 14th DVOA against the run.

 

DraftKings Wide Receivers - Week 15 DFS Picks

Michael Thomas - WR, NO vs NYJ (DK - $7,400)

Thomas is coming off his best game of the season, and is in an even better spot this week. He is up against the Jets who have the 27th DVOA against pass, and the 30th DVOA against WR1. This is a prime spot for him, and has massive PPR value. He has seen eight or more targets in 12 of 13 games this season, and should be able to replicate that production. He is almost a lock for 12 or more DraftKings points, and should be good for any format this week.

Keelan Cole - WR, JAX vs HOU (DK - $3,700)

Cole has 27 targets over his last five games, and for his price, he offers a ton of savings. He is up against the Texans who have the 18th DVOA against the pass, and the 27th DVOA against WR2. Cole also has touchdowns in two straight weeks, and is in a good spot to repeat that. This game may not have the highest over-under, but Cole offers some much needed savings on this full slate.

 

DraftKings Tight End - Week 15 DFS Pick

Evan Engram - TE, NYG vs PHI (DK - $5,600)

Engram has seen six or more targets in 11 of his 13 games this season, and has become the favorite receiver of Eli Manning. He is up against the Eagles, who have the 19th DVOA against tight ends, putting him in a good spot to succeed this week. If you don't want to spend all the way up to get Gronk or Kelce, he makes a good option in the middle. Good for any format this week, as he has PPR value, along with touchdown upside.

 

DraftKings Defense - Week 15 DFS Pick

Minnesota Vikings vs Cincinnati Bengals - (DK - $3,500)

The Vikings are averaging three more DraftKings points at home this season, and are now up against a Bengals team who has been very inconsistent on offense. They have seven sacks over their past four games, and two interceptions over that span. They are one of the more expensive options on the slate, so getting up to them in price price can be hard in cash games, but they are a great tournament option.

 

More Week 15 DFS Analysis

 




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Mo Alie-Cox

Re-Signing with Colts
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Darnell Mooney

Signing with Giants on One-Year Deal
Zach Neto

is Removed After Suffering Hand Injury
TB

Nicholas Paul Rejoins Lightning Lineup
Cole Caufield

Cleared to Play Saturday
Alex Tuch

Set to Return Saturday
Bobby Brink

Remains Out Saturday
J.T. Miller

Returns to Action Saturday
Joe Ryan

Won't Pitch in the World Baseball Classic
Courtland Sutton

Will Courtland Sutton Lose Targets to Younger Teammates?
Rashee Rice

Looking to Return to Rookie Form?
Omarion Hampton

Has High Upside with New Offensive Coordinator
Trey Lance

Returns to the Chargers on a One-Year Deal
A.J. Brown

Rams Out on A.J. Brown, Trade to Patriots Likely?
Calvin Ridley

Restructures Deal with Titans
Jonathan Taylor

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Tony Pollard

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David Montgomery

Has Contract Updated by Texans
Zack Wheeler

Throws First Live BP Session on Saturday
Chris Godwin Jr.

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LeQuint Allen Jr.

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Isaiah Davis

Appears Buried on the Jets Running Back Depth Chart
Merrill Kelly

Expected to Open Season on the Injured List
Christian Kirk

Dynasty Value is Fading Heading into 2026
Anthony Richardson Sr.

Packers Interested in Acquiring Anthony Richardson Sr.?
Kevin Gausman

Named Toronto's Opening Day Starter
Kyle Stowers

Back in Grapefruit League Lineup
Kevin Porter Jr.

Questionable Against Hawks
Devin Carter

Out Saturday Against Clippers
Russell Westbrook

Set to Return Against Clippers
Derrick White

Expected to Play Saturday Against Wizards
Michael Porter Jr.

Likely to Miss Second Straight Game
Nicolas Claxton

to Rest Saturday Against Philadelphia
Ace Bailey

Leaves Friday's Game Early with Concussion
Radko Gudas

Handed a Five-Game Suspension
Auston Matthews

to Miss Rest of Season
Emil Heineman

Scores Twice Against the Kings
Joel Hofer

Shuts Down the Oilers
Giannis Antetokounmpo

Could Miss Saturday's Game Vs. Hawks
Keegan Murray

to Be Re-Evaluated in Two Weeks
Aaron Gordon

Expected Back Saturday Vs. Lakers
Jamal Murray

Expected to Suit Up Saturday
Collin Sexton

to Miss Third Straight Game
Jalen Smith

is Ruled Out for Friday's Game
Robert Williams III

is Unavailable for Friday's Contest
Draymond Green

is Downgraded to Out on Friday
De'Anthony Melton

to Play on Friday
Ayo Dosunmu

is Cleared for Friday's Game
Anthony Edwards

is Available on Friday
Norman Powell

is Tagged as Questionable for Saturday
Victor Wembanyama

Questionable Saturday Vs. Hornets
Andrew Wiggins

to Miss Fifth Straight Game
Francisco Lindor

Takes Full Batting Practice on Friday
Brandon Woodruff

Still TBD for Opening Day
Trevor Rogers

to Start on Opening Day for Orioles
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Looks To Remain Undefeated In The UFC
Josh Emmett

In Dire Need Of Victory
Gillian Robertson

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Amanda Lemos

Set For Co-Main Event
Oumar Sy

Looks To Win Back-To-Back Fights
Ion Cutelaba

Looks To Get Back In The Win Column
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Racks Up Four Points in Victory Over Kraken
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Alexis Lafreniere Stays Hot in Winnipeg
Semyon Varlamov

Won't Return This Season
Alexander Romanov

Could Return for Playoffs
Declan Carlile

Hurt on Thursday Night
Wyatt Kaiser

Sustains Upper-Body Injury Thursday
Erik Gudbranson

Could Be an Option Saturday
Auston Matthews

Exits Game With Injury
Blake Snell

Around Six Weeks From Being Fully Built Up
Zack Wheeler

to Face Hitters in Live Batting Practice on Saturday
Gerrit Cole

Could Pitch in a Spring Game Next Week
Matthew Boyd

Named the Cubs' Opening Day Starter
Francisco Lindor

Remains on Schedule for Opening Day
Bryce Miller

Shuts Down Bullpen Due to More Oblique Discomfort
Zac Gallen

Named Arizona's Opening Day Starter
Kyle Teel

Could Miss 4-6 Weeks With Hamstring Strain
Hideki Matsuyama

Brings Strong Course History to TPC Sawgrass
Josh Hader

to Start the Year on the Injured List
Adam Scott

in Strong Form Ahead of The Players
Kyle Teel

Exits Tuesday's Game With Hamstring Injury
Rickie Fowler

on Quite the Run Heading to TPC Sawgrass
Sepp Straka

Needs to Forget What Happened Sunday at Bay Hill
Jordan Spieth

an Enigma Heading to The Players Championship
Justin Rose

Trying to Pick Up the Pieces in Florida
Maverick McNealy

Bounces Back at Arnold Palmer Invitational
Brooks Koepka

Continues His Florida Swing With Some Momentum
Nicolai Hojgaard

in Strong Form Ahead of The Players
Robert MacIntyre

a Volatile Option at The Players
Matt Fitzpatrick

Looks to Return to Top Form at The Players
Sam Burns

a High-Risk, High-Reward Option at The Players
Keegan Bradley

Hard to Trust at The Players
Xander Schauffele

Rounding into Form Heading to Players Championship
Rory McIlroy

Set to Return at Players Championship to Defend Title
Jake Knapp

Set to Return at Players Championship
Viktor Hovland

Continues Strong Start to 2026 Season
Rasmus Hojgaard

Looking for Bounce-Back at Players Championship
Tommy Fleetwood

Will Need to Find Putter to Compete at Players Championship
Akshay Bhatia

Continues Improving Heading to Players Championship
Merrill Kelly

Set to Make Spring Training Debut on Friday
Justin Thomas

Continues Competitive Return at The Players Championship
Max Holloway

Drops Decision At UFC 326
Charles Oliveira

Becomes The New BMF Champion
Caio Borralho

Bounces Back
Reinier de Ridder

Reinier De Ridder Loses Back-To-Back Fights
Rob Font

Gets Dominated
Raul Rosas Jr.

Extends His Win Streak
Michael Johnson

Suffers Second-Round Knockout Loss
Drew Dober

Knocks Out Michael Johnson
Ryan Blaney

Earns his Second Consecutive Phoenix Cup Series Win
Christopher Bell

Falls Short of Victory Despite Dominating at Phoenix
Kyle Larson

Earns Hard-Fought Finish of Third at Phoenix
Denny Hamlin

Quietly Gains Another Top-Five Finish at Phoenix
Joey Logano

Crashes out at Phoenix Despite Strong Run
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF