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DraftKings Lineup Picks (Week 15) - NFL DFS Advice

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 15 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 14!

 

DraftKings Quarterbacks - Week 15 DFS Picks

Matt Ryan - ATL @ TB (DK - $6,300)

Ryan is coming off a very rough three interception game, but now has a very favorable match up in his favor. He is at division rival Tampa Bay, who has the 31st DVOA against the pass, who when he played them earlier this season, he put up over 300 yards and one touchdown. This is a level of production that he should be able to match, considering the Falcons have an implied team total of 27 points, which is third highest on the slate. This game is on Monday night, so you will have to have to play on one of the expanded slates to get to him. Given the match up, he has multi-touchdown upside and a good play for GPPs.

Derek Carr - OAK vs DAL (DK - $5,700)

Carr has scored 14.5 or more DraftKings points in six of his last seven games, and is facing a weak defensive opponent. At his price, he really only needs about 16 DK points in order to reach 3x value for cash games. He is up against the Cowboys, who have the 22nd DVOA against the pass, and have shown they are very weak in the secondary. Carr will be without Amari Cooper, so pairing him with Michael Crabtree is a good idea for either format. Carr along with the Raiders haven't been consistent this season, so some DFS player might be afraid to roster him, opening the chance for lower ownership.

 

DraftKings Running Backs - Week 15 DFS Picks

Dion Lewis - RB, NE @ PIT (DK - $5,400)

Lewis has double digit rushing attempts in seven of his last last eight games, along with 11 targets in his lat four games. This game vs the Steelers has an over-under of 53 points, making it the highest of the slate, so you will want some exposure to this game. He isn't too expensive, and with the snaps he is seeing, he can pay off his salary quickly. The Steelers have the 29th DVOA against running backs in the passing game, which makes this a fantastic match up, considering his PPR value out of the backfield.

LeSean McCoy - RB, BUF vs MIA (DK - $8,400)

McCoy is in line to see plenty of work this week considering the fact the Bills are in a tough spot at quarterback. Seemingly for the past month, the Bills have a rotating cast at quarterbacks, because of injuries. McCoy had 32 carries last week, which is super high, but that was mainly due to the weather. He won't see that type of volume every week, but with Tyrod Taylor on the injury report, he could see close to it. McCoy is up against the Dolphins who have the 14th DVOA against the run.

 

DraftKings Wide Receivers - Week 15 DFS Picks

Michael Thomas - WR, NO vs NYJ (DK - $7,400)

Thomas is coming off his best game of the season, and is in an even better spot this week. He is up against the Jets who have the 27th DVOA against pass, and the 30th DVOA against WR1. This is a prime spot for him, and has massive PPR value. He has seen eight or more targets in 12 of 13 games this season, and should be able to replicate that production. He is almost a lock for 12 or more DraftKings points, and should be good for any format this week.

Keelan Cole - WR, JAX vs HOU (DK - $3,700)

Cole has 27 targets over his last five games, and for his price, he offers a ton of savings. He is up against the Texans who have the 18th DVOA against the pass, and the 27th DVOA against WR2. Cole also has touchdowns in two straight weeks, and is in a good spot to repeat that. This game may not have the highest over-under, but Cole offers some much needed savings on this full slate.

 

DraftKings Tight End - Week 15 DFS Pick

Evan Engram - TE, NYG vs PHI (DK - $5,600)

Engram has seen six or more targets in 11 of his 13 games this season, and has become the favorite receiver of Eli Manning. He is up against the Eagles, who have the 19th DVOA against tight ends, putting him in a good spot to succeed this week. If you don't want to spend all the way up to get Gronk or Kelce, he makes a good option in the middle. Good for any format this week, as he has PPR value, along with touchdown upside.

 

DraftKings Defense - Week 15 DFS Pick

Minnesota Vikings vs Cincinnati Bengals - (DK - $3,500)

The Vikings are averaging three more DraftKings points at home this season, and are now up against a Bengals team who has been very inconsistent on offense. They have seven sacks over their past four games, and two interceptions over that span. They are one of the more expensive options on the slate, so getting up to them in price price can be hard in cash games, but they are a great tournament option.

 

More Week 15 DFS Analysis

 




REAL-TIME FANTASY NEWS

Troy Terry

Has Special Playoffs Debut
Dan Vladar

Leads Flyers to Victory With 27-Save Shutout
Yakov Trenin

Suffers Upper-Body Injury in Game 2
Rasmus Sandin

to Miss Start of 2026-27
CJ McCollum

Shines at MSG in Game 2
Donovan Mitchell

Extends 30-Point Streak
Jakob Poeltl

Gets Benched for Second Half
Brandon Ingram

Continues to Struggle
Al Horford

Undecided on Future
Brandin Podziemski

Wants to Stay With Warriors Long-Term
Max Muncy

With Another Two-Homer Game, Becoming Must-Add Off Waiver Wire
Seattle Seahawks

Seahawks "Looking to Trade Back" in This Week's Draft
NFL

Garrett Nussmeier Could Need Surgery Down the Road on his Spine
Kayvon Thibodeaux

Now Unlikely to be Dealt
Anton Harrison

Jaguars Exercise Anton Harrison's Fifth-Year Option
Darnell Wright

Bears Picking Up Fifth-Year Option for Darnell Wright
Sean Tucker

Buccaneers Re-Sign Running Back Sean Tucker
Fred Warner

Without Restrictions at Start of Offseason Program
Brandon Aiyuk

49ers Talking Trade Regarding Brandon Aiyuk With Draft Looming
Anthony Richardson Sr.

Not Present for Start of Offseason Program
Daniel Jones

Progressing "Really Well," Colts Hoping he's Ready for Week 1
Jimmy Garoppolo

Considering Retirement
Matthew Stafford

Rams, Matthew Stafford Have Made "Significant Progress" Toward New Extension
Patrick Mahomes

Present for Start of Team's Offseason Program
NFL

Jadarian Price a Potential First-Rounder in Rookie Drafts
Jordan McLaughlin

Ruled Out for Game 2
NFL

Nicholas Singleton a Mid-Round Pick with Upside
Ron Harper Jr.

Probable for Game 2
Austin Reaves

to Remain Out Tuesday
NFL

Is Makai Lemon the Top Rookie Receiver in Fantasy Football?
Luka Dončić

Luka Doncic Still Out Tuesday
Anthony Edwards

Active on Monday Night
Kevin Durant

a Game-Time Decision on Tuesday
Ronald Acuña Jr.

Ronald Acuna Jr. Day-to-Day After Being Hit on the Hand on Monday
Mick Abel

Injury Described as "Not Too Serious"
Brendan Donovan

Mariners Place Brendan Donovan on Injured List With Groin Strain
NFL

Is Fernando Mendoza an Undisputed First-Round Pick in Rookie Drafts?
NFL

Omar Cooper Jr. a Top-Five Rookie Receiver in Fantasy Football?
Joel Embiid

is Officially Ruled Out for Game 2
Sonny Gray

Heading to the Injured List With Hamstring Injury
Victor Wembanyama

Wins Defensive Player of the Year
Puka Nacua

Present for Rams First Day of Offseason Program
Odell Beckham Jr.

Works Out for Giants on Monday
OG Anunoby

is Available to Play for Monday's Game 2
Onyeka Okongwu

is Cleared to Play During Game 2 on Monday
Brandon Aubrey

Cowboys Make Brandon Aubrey the Highest-Paid Kicker in the League
Immanuel Quickley

is Ruled Out for Game 2
Edwin Díaz

Edwin Diaz Expected to Miss Around Three Months
Edwin Uceta

Shut Down for 2-3 Weeks; Is he Still Stash-Worthy?
Charle-Edouard D'Astous

Doubtful for Game 2
Brad Keller

Will "Probably" Earn First Save Situation in Modified Phillies Bullpen
Roope Hintz

to Miss at Least Two More Games
Edwin Díaz

Edwin Diaz Placed on 15-Day Injured List with Elbow Injury
Ross Johnston

Won't Play in Game 1 Against Oilers
Artem Zub

Considered a Game-Time Decision Monday
Tyler Kleven

Remains Out Monday
Jason Dickinson

a Game-Time Call Monday
Leon Draisaitl

Expected to Return Monday
Tyler Reddick

Earns His Fifth Win of the 2026 Season at Kansas
Kyle Larson

Finishes as the Runner-Up at Kansas
Chase Briscoe

Rallies for A New Career-Best Finish at Kansas
Denny Hamlin

Leads the Most Laps at Kansas but Misses Out on Victory
Christopher Bell

Falls Out of Contention for Kansas Victory on Final Restart
Mike Malott

Scores Third-Round TKO Win
Sonny Gray

Leaves Monday's Start Early With Hamstring Tightness
Gilbert Burns

Retires After UFC Winnipeg Loss
Charles Jourdain

Extends Winning Streak
Mick Abel

Twins Placing Mick Abel on Injured List With Elbow Inflammation
Kyler Phillips

Drops Decision At UFC Winnipeg
Mandel Nallo

Suffers First-Round TKO Loss In His UFC Debut
Jai Herbert

Scores First-Round TKO Win
Karine Silva

Gets Dominated at UFC Winnipeg
Jasmine Jasudavicius

Dominates Karine Silva
Deni Avdija

Posts 30-Point Double-Double in Loss
Paolo Banchero

Leads Magic in Game 1 Win
Jalen Duren

Posts Quiet Line in Series Opener
Cade Cunningham

Erupts for 39 Points in Playoff Opener
Logan Cooley

Scores Mammoth's First-Ever Playoff Goal
David Pastrnak

Finishes Game 1 Loss With Three Points
Tage Thompson

Bags Three Points in Postseason Debut
Jake Guentzel

Records Three Assists Sunday
Juraj Slafkovsky

Nets Unique Hat Trick in Playoff Opener
Charle-Edouard D'Astous

Hurt in Game 1 Loss
Leon Draisaitl

Could Be Ready for Game 1 Against Ducks
Corbin Carroll

Expected Back Tuesday; Injury Concern Appears Minor
Juan Soto

is on Track to Return Next Homestand
Corbin Carroll

Exits Sunday's Game with Back Tightness
Artem Zub

Uncertain for Game 2
Karel Vejmelka

Makes Playoff Debut Sunday
Carter Hart

in Vegas Crease for Playoff Opener
Tarik Skubal

Fans 10 in Win Over Red Sox on Saturday
Raisel Iglesias

Dealing With Shoulder Issue
Kyle Larson

Should not be Underestimated for the Win at Kansas
Denny Hamlin

Can Denny Hamlin Dominate at Kansas Again?
NASCAR

Christoper Bell Should Contend for First Win at Kansas
Tyler Reddick

Fastest in Practice and Qualifying for Kansas Race
Ryan Blaney

Could Score another Top-10 Finish at Kansas
Ty Gibbs

Poised to Continue Hot Streak at Kansas
Chris Buescher

Always Consistent, Has Speed Heading Into Kansas
William Byron

is A Solid DFS Option for Kansas Lineups
Carson Hocevar

Poised for Career-Best Run at Kansas
Chase Briscoe

Is Chase Briscoe Worth Rostering for DFS at Kansas?
Chase Elliott

Is A Favorable DFS Option for Kansas Lineups
Joey Logano

Could Joey Logano be Considered Playable In DFS This Week at Kansas?
NASCAR

Bubba Wallace is A Favorable Driver to Consider for Kansas Lineups
Ross Chastain

Is Ross Chastain A Worthy DFS Option for Kansas?
Brad Keselowski

Could Brad Keselowski be A Sneaky DFS Option for Kansas?
Daniel Suarez

Should DFS Managers Roster Daniel Suarez at Kansas?
Jhoan Duran

Placed on 15-Day Injured List With Oblique Strain
Kyle Stowers

Will be Activated on Sunday
Max Muncy

has Another Multi-Homer Game at Coors Field
Lourdes Gurriel Jr.

Expected to Make Season Debut on Saturday
Austin Riley

Hits Two Home Runs in Shutout Win Over Phillies
Mike Malott

A Favorite At UFC Winnipeg
Gilbert Burns

Set For UFC Winnipeg Main Event
Kyler Phillips

Set UFC Winnipeg Co-Main Event
Charles Jourdain

Looks To Extend His Win Streak
Jai Herbert

An Underdog At UFC Winnipeg
Mandel Nallo

Set For His UFC Debut
Karine Silva

Looks To Get Back In The Win Column
Jasmine Jasudavicius

Looks To Bounce Back
CFB

Michigan Lands Commitment From Quarterback Kamden Lopati
Sahith Theegala

Brings Strong Form Into Harbour Town
Wyndham Clark

Needs Putter to Show Up at RBC Heritage
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