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DraftKings Lineup Picks (Week 15) - NFL DFS Advice

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 15 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 14!

 

DraftKings Quarterbacks - Week 15 DFS Picks

Matt Ryan - ATL @ TB (DK - $6,300)

Ryan is coming off a very rough three interception game, but now has a very favorable match up in his favor. He is at division rival Tampa Bay, who has the 31st DVOA against the pass, who when he played them earlier this season, he put up over 300 yards and one touchdown. This is a level of production that he should be able to match, considering the Falcons have an implied team total of 27 points, which is third highest on the slate. This game is on Monday night, so you will have to have to play on one of the expanded slates to get to him. Given the match up, he has multi-touchdown upside and a good play for GPPs.

Derek Carr - OAK vs DAL (DK - $5,700)

Carr has scored 14.5 or more DraftKings points in six of his last seven games, and is facing a weak defensive opponent. At his price, he really only needs about 16 DK points in order to reach 3x value for cash games. He is up against the Cowboys, who have the 22nd DVOA against the pass, and have shown they are very weak in the secondary. Carr will be without Amari Cooper, so pairing him with Michael Crabtree is a good idea for either format. Carr along with the Raiders haven't been consistent this season, so some DFS player might be afraid to roster him, opening the chance for lower ownership.

 

DraftKings Running Backs - Week 15 DFS Picks

Dion Lewis - RB, NE @ PIT (DK - $5,400)

Lewis has double digit rushing attempts in seven of his last last eight games, along with 11 targets in his lat four games. This game vs the Steelers has an over-under of 53 points, making it the highest of the slate, so you will want some exposure to this game. He isn't too expensive, and with the snaps he is seeing, he can pay off his salary quickly. The Steelers have the 29th DVOA against running backs in the passing game, which makes this a fantastic match up, considering his PPR value out of the backfield.

LeSean McCoy - RB, BUF vs MIA (DK - $8,400)

McCoy is in line to see plenty of work this week considering the fact the Bills are in a tough spot at quarterback. Seemingly for the past month, the Bills have a rotating cast at quarterbacks, because of injuries. McCoy had 32 carries last week, which is super high, but that was mainly due to the weather. He won't see that type of volume every week, but with Tyrod Taylor on the injury report, he could see close to it. McCoy is up against the Dolphins who have the 14th DVOA against the run.

 

DraftKings Wide Receivers - Week 15 DFS Picks

Michael Thomas - WR, NO vs NYJ (DK - $7,400)

Thomas is coming off his best game of the season, and is in an even better spot this week. He is up against the Jets who have the 27th DVOA against pass, and the 30th DVOA against WR1. This is a prime spot for him, and has massive PPR value. He has seen eight or more targets in 12 of 13 games this season, and should be able to replicate that production. He is almost a lock for 12 or more DraftKings points, and should be good for any format this week.

Keelan Cole - WR, JAX vs HOU (DK - $3,700)

Cole has 27 targets over his last five games, and for his price, he offers a ton of savings. He is up against the Texans who have the 18th DVOA against the pass, and the 27th DVOA against WR2. Cole also has touchdowns in two straight weeks, and is in a good spot to repeat that. This game may not have the highest over-under, but Cole offers some much needed savings on this full slate.

 

DraftKings Tight End - Week 15 DFS Pick

Evan Engram - TE, NYG vs PHI (DK - $5,600)

Engram has seen six or more targets in 11 of his 13 games this season, and has become the favorite receiver of Eli Manning. He is up against the Eagles, who have the 19th DVOA against tight ends, putting him in a good spot to succeed this week. If you don't want to spend all the way up to get Gronk or Kelce, he makes a good option in the middle. Good for any format this week, as he has PPR value, along with touchdown upside.

 

DraftKings Defense - Week 15 DFS Pick

Minnesota Vikings vs Cincinnati Bengals - (DK - $3,500)

The Vikings are averaging three more DraftKings points at home this season, and are now up against a Bengals team who has been very inconsistent on offense. They have seven sacks over their past four games, and two interceptions over that span. They are one of the more expensive options on the slate, so getting up to them in price price can be hard in cash games, but they are a great tournament option.

 

More Week 15 DFS Analysis

 




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Pat Bryant

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Luis Robert Jr.

Likely to Land on the Injured List
Troy Franklin

Dynasty Expectations Low for Troy Franklin
Trevor Lawrence

Dynasty Value Remains High Despite Quiet Jaguars Offseason
Courtland Sutton

Dynasty Value Unaffected by NFL Draft
Clayton Keller

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Pavel Dorofeyev

Nets Special Hat Trick in Game 5 Win
Dan Vladar

Backstops Flyers to Series-Clinching Win
Leon Draisaitl

Oilers to Use Connor McDavid and Leon Draisaitl on Same Line Thursday
Brady Tkachuk

Remains Committed to Senators
Arttu Hyry

Could Be Available Thursday
James Harden

Contributes in All Areas Wednesday
Dennis Schröder

Dennis Schroder Plays Key Role in Game 5 Win
RJ Barrett

Records First Double-Double of the Season
Austin Reaves

Contributes 22 Points Off the Bench in Game 5 Loss
LeBron James

Regains Scoring Touch Wednesday
Paolo Banchero

Scores 45 Points in Game 5 Loss
New York Jets

Jets Pick Up Will McDonald's Fifth-Year Option
Azeez Al-Shaair

Texans, Azeez Al-Shaair Agree to Three-Year Extension
KC Concepcion

Looking to Build Chemistry With Second-Year QB
Deshaun Watson

"Looks Great," Leading QB Battle After First Minicamp?
George Pickens

Signs the Franchise Tag on Wednesday
Cade Cunningham

Helps Pistons Survive With 45-Point Effort
Jock Landale

to Remain Unavailable in Game 6
Peyton Watson

to Remain Out Thursday
Austin Reaves

Cleared to Return Wednesday
Luka Dončić

Luka Doncic Remains Without Timetable for Return
Brandon Nimmo

Leaves Wednesday's Game With Hamstring Tightness
Brandon Ingram

Won't Play in Second Half Wednesday
Aaron Gordon

Questionable for Game 6
Josh Hart

Iffy for Game 6
Joel Embiid

Likely to Play in Game 6
Bones Hyland

Could Miss Game 6
Kevin Huerter

Not Available for Game 5
Jonathan Isaac

Remains Out for Game 5
Franz Wagner

Won't Play in Game 5
MLB

Phillies-Giants Postponed on Wednesday Due to Rain
Nils Lundkvist

to Remain Out Thursday
Jonas Brodin

Uncertain for Game 6
Matvei Michkov

Expected to Rejoin Flyers Lineup Wednesday
Noah Ostlund

Set to Miss "a Period of Time"
Viktor Arvidsson

Doubtful for Game 6 Against Sabres
Barrett Hayton

Close to Returning
Charle-Edouard D'Astous

a Game-Time Call Wednesday
Brandon Aiyuk

Decision Could Come in Late May
Bryce Young

Panthers Pick Up Bryce Young's Fifth-Year Option
MLB

Orioles-Astros Game Postponed Due to Inclement Weather on Wednesday
Gary Woodland

Riding Momentum Into Cadillac Championship
Jordan Spieth

Brings Boom-or-Bust Potential to Cadillac Championship
Adam Scott

Looks Poised for Another Strong Finish at Doral
Maverick McNealy

Needs Approach Game to Click at Doral
George Springer

Being Activated From Injured List, Won't Start on Wednesday
Wyatt Langford

Expected to be Activated on Saturday
Garrett Crochet

Goes on Injured List With Shoulder Inflammation
CFB

Jameson Williams Files Lawsuit Against NCAA, SEC, Big Ten
Junior Caminero

Back in Wednesday's Lineup After Injury Scare
Harry Hall

Volatility Continues at Cadillac Championship
Tommy Fleetwood

Looks to Rebound at Trump National Doral
Pierceson Coody

a Risky Value Play at Cadillac Championship
Deebo Samuel Sr.

Will Deebo Samuel Sr. Find a New Team Before Training Camps Open?
Jalen Johnson

Collects Second Playoff Double-Double
Akshay Bhatia

Offers Upside with Risk at Cadillac Championship
Elic Ayomanor

Dynasty Stock Way Down After NFL Draft
Jalen Brunson

Pours 39 Points on Hawks in Game 5
Darius Slayton

Dynasty Value Fading After Busy Giants Offseason
David Njoku

With the NFL Draft Over, David Njoku Could Soon Find a Team
Tyler Warren

a Major Offseason Winner
Connor McDavid

Extends Multi-Point Streak Tuesday
Justin Thomas

a Scary Proposition at Cadillac Championship
Nikolaj Ehlers

Hurricanes Hope to Have Nikolaj Ehlers Back for Second Round
Alexander Nikishin

Could Be Available in Round 2
Victor Hedman

Logs Full Practice
Scottie Scheffler

The Leading Favorite at Cadillac Championship
Noah Ostlund

Likely to Miss Time Due to Lower-Body Injury
Arttu Hyry

Unlikely to Play Thursday
Collin Morikawa

Still a Smash Play at Cadillac Championship
Jonas Brodin

Spotted Using Crutches After Game 5
Viktor Hovland

Showed at Augusta He Can Finish Well
Sepp Straka

Attempting to Finish Better in Miami
PGA

J.J Spaun Enduring Roller Coaster Start to 2026
Min Woo Lee

Seeks to Make Adjustments at Cadillac Championship
Max Homa

May Struggle at Old Doral This Weekend
Ben Griffin

Rebounds From Rough Stretch as Miami Looms
Shane Lowry

Searching For Answers at Cadillac Championship
Russell Henley

Daunting Test at Doral Likely Not a Place For Russell Henley
Justin Rose

Returns to Action After Finishing Third at Masters Tournament
Hideki Matsuyama

Has The Approach Game to Win at Cadillac Championship
Junior Caminero

Suffers Jaw Contusion on Tuesday, Considered Day-to-Day
Pete Fairbanks

Going on Injured List With Nerve Irritation
Spencer Strider

to Make Season Debut This Weekend
Roope Hintz

Likely to Miss Entire First-Round Series
Luis Robert Jr.

Out on Tuesday With Back Tightness
Juan Soto

Dealing With Forearm Tightness, Serving as DH on Tuesday
CFB

Brendan Sorsby Facing Potential Permanent Loss of Eligibility
Manny Machado

Departs Early With Undisclosed Injury on Monday
Philadelphia Phillies

Phillies Fire Manager Rob Thomson
Elmer Rodríguez

Yankees to Promote Top Pitching Prospect Elmer Rodriguez
Pete Fairbanks

Pulled on Monday With "Unusual Sensation" in his Thumb
Giancarlo Stanton

Heading to Injured List With Calf Strain
Travis Bazzana

Guardians Calling Up Former First Overall Pick Travis Bazzana
Will Smith

Back in Action in Series Opener Against Marlins
Carson Hocevar

Scores his First Career NASCAR Cup Series Victory at Talladega
Chris Buescher

Misses out on Winning at Talladega by Finishing Second
Alex Bowman

Earns First Top-Five Finish at Talladega Since Returning From Injury
Chase Elliott

Scores A Fourth-Place Finish at Talladega
Zane Smith

Nabs First Top-Five Finish of the 2026 Season at Talladega
CFB

Texas Tech Quarterback Brendan Sorsby Enters Rehab
Youssef Zalal

Suffers Unanimous-Decision Loss
Aljamain Sterling

Wins Back-To-Back Fights
Norma Dumont

Drops Decision At UFC Vegas 116
Joselyne Edwards

Scores Upset Win
Alexander Hernandez

Gets Dominated
Alexander Hernandez

Rafa Garcia Dominates Alexander Hernandez
Adrian Luna Martinetti

Unsuccessful In His UFC Debut
Davey Grant

Gets Back In The Win Column
Denny Hamlin

Is Denny Hamlin Worth Rostering for Talladega?
NASCAR

Is Bubba Wallace Playable in Talladega DFS Lineups?
Tyler Reddick

Stay Away From Tyler Reddick at Talladega
Ryan Blaney

Can Ryan Blaney Shake Off The Bad Luck at Talladega?
Austin Cindric

Could Contend For Another Talladega Win
Kyle Busch

an Easy DFS Pick at Talladega
Ricky Stenhouse Jr

. a High-Risk, High-Reward Pick at Talladega
Todd Gilliland

a Sleeper to Watch at Talladega
Brad Keselowski

Is Brad Keselowski Worth Rostering for Talladega Lineups?
Chase Briscoe

Could Chase Briscoe be A Sneaky Tournament Play for Talladega Lineups?
Christopher Bell

Should DFS Managers Trust Christopher Bell at Talladega?
Ty Gibbs

Is A DFS Risk for Talladega Lineups
Youssef Zalal

Set For UFC Vegas 116 Main Event
Aljamain Sterling

An Underdog At UFC Vegas 116
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