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DraftKings Lineup Picks (Week 15) - NFL DFS Advice

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 15 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 14!

 

DraftKings Quarterbacks - Week 15 DFS Picks

Matt Ryan - ATL @ TB (DK - $6,300)

Ryan is coming off a very rough three interception game, but now has a very favorable match up in his favor. He is at division rival Tampa Bay, who has the 31st DVOA against the pass, who when he played them earlier this season, he put up over 300 yards and one touchdown. This is a level of production that he should be able to match, considering the Falcons have an implied team total of 27 points, which is third highest on the slate. This game is on Monday night, so you will have to have to play on one of the expanded slates to get to him. Given the match up, he has multi-touchdown upside and a good play for GPPs.

Derek Carr - OAK vs DAL (DK - $5,700)

Carr has scored 14.5 or more DraftKings points in six of his last seven games, and is facing a weak defensive opponent. At his price, he really only needs about 16 DK points in order to reach 3x value for cash games. He is up against the Cowboys, who have the 22nd DVOA against the pass, and have shown they are very weak in the secondary. Carr will be without Amari Cooper, so pairing him with Michael Crabtree is a good idea for either format. Carr along with the Raiders haven't been consistent this season, so some DFS player might be afraid to roster him, opening the chance for lower ownership.

 

DraftKings Running Backs - Week 15 DFS Picks

Dion Lewis - RB, NE @ PIT (DK - $5,400)

Lewis has double digit rushing attempts in seven of his last last eight games, along with 11 targets in his lat four games. This game vs the Steelers has an over-under of 53 points, making it the highest of the slate, so you will want some exposure to this game. He isn't too expensive, and with the snaps he is seeing, he can pay off his salary quickly. The Steelers have the 29th DVOA against running backs in the passing game, which makes this a fantastic match up, considering his PPR value out of the backfield.

LeSean McCoy - RB, BUF vs MIA (DK - $8,400)

McCoy is in line to see plenty of work this week considering the fact the Bills are in a tough spot at quarterback. Seemingly for the past month, the Bills have a rotating cast at quarterbacks, because of injuries. McCoy had 32 carries last week, which is super high, but that was mainly due to the weather. He won't see that type of volume every week, but with Tyrod Taylor on the injury report, he could see close to it. McCoy is up against the Dolphins who have the 14th DVOA against the run.

 

DraftKings Wide Receivers - Week 15 DFS Picks

Michael Thomas - WR, NO vs NYJ (DK - $7,400)

Thomas is coming off his best game of the season, and is in an even better spot this week. He is up against the Jets who have the 27th DVOA against pass, and the 30th DVOA against WR1. This is a prime spot for him, and has massive PPR value. He has seen eight or more targets in 12 of 13 games this season, and should be able to replicate that production. He is almost a lock for 12 or more DraftKings points, and should be good for any format this week.

Keelan Cole - WR, JAX vs HOU (DK - $3,700)

Cole has 27 targets over his last five games, and for his price, he offers a ton of savings. He is up against the Texans who have the 18th DVOA against the pass, and the 27th DVOA against WR2. Cole also has touchdowns in two straight weeks, and is in a good spot to repeat that. This game may not have the highest over-under, but Cole offers some much needed savings on this full slate.

 

DraftKings Tight End - Week 15 DFS Pick

Evan Engram - TE, NYG vs PHI (DK - $5,600)

Engram has seen six or more targets in 11 of his 13 games this season, and has become the favorite receiver of Eli Manning. He is up against the Eagles, who have the 19th DVOA against tight ends, putting him in a good spot to succeed this week. If you don't want to spend all the way up to get Gronk or Kelce, he makes a good option in the middle. Good for any format this week, as he has PPR value, along with touchdown upside.

 

DraftKings Defense - Week 15 DFS Pick

Minnesota Vikings vs Cincinnati Bengals - (DK - $3,500)

The Vikings are averaging three more DraftKings points at home this season, and are now up against a Bengals team who has been very inconsistent on offense. They have seven sacks over their past four games, and two interceptions over that span. They are one of the more expensive options on the slate, so getting up to them in price price can be hard in cash games, but they are a great tournament option.

 

More Week 15 DFS Analysis

 




REAL-TIME FANTASY NEWS

LeBron James

Available Versus Sacramento
Zion Williamson

Ruled Out Versus Clippers
Shelby Miller

Officially Placed on 60-Day Injured List
Kevin Love

Resting Monday Against Nuggets
Jacob deGrom

is Nearing Spring Debut
Tristan Vukcevic

Could Miss Game Vs. Houston
José Soriano

Jose Soriano has Start Pushed Back
John Collins

Cleared to Play Sunday
Bobby Miller

Being Viewed as Reliever
Brandon Clarke

to be Re-Evaluated in Two Weeks
Walker Jenkins

is Diagnosed with Hamstring Strain
Caleb Martin

Returns Against Thunder
P.J. Washington

Naji Marshall Ruled Out Sunday
Kyshawn George

Could Miss Game Against Houston
Baylor Scheierman

Cleared to Play Sunday
Rui Hachimura

Set to Return Against Kings
LeBron James

Questionable Against Kings
Jonathan Drouin

Unavailable Sunday
Darcy Kuemper

Won't Play Monday Due to Illness
Andrew Mangiapane

Oilers Place Andrew Mangiapane on Waivers
Jabari Smith Jr.

Still Out on Monday
Uvis Balinskis

Out Sunday
Jalen Johnson

Back on Sunday Night
Dmitry Kulikov

Comes Off Injured Reserve
Mark Stone

Exits With Injury Sunday
Deni Avdija

Remains Out on Sunday
Zach Edey

to Undergo Another Ankle Surgery
Merrill Kelly

"Optimistic" About Being Ready by Opening Day
Gabriel Moreno

Can Gabriel Moreno Put Together a Fully Healthy Season in 2026?
Mark Vientos

May Be Limited to Part-Time Role in New York
Kyler Murray

Likely to be Released
Noah Cameron

Can Noah Cameron Repeat His Breakout 2025 Season?
Justin Steele

"Full-Go" on Throwing, Still Eyeing May or June Return
Travis Etienne Jr.

Not Expected to be Franchise-Tagged
Aaron Jones Sr.

Vikings Planning to Release Aaron Jones Sr.?
Samuel Basallo

is Returning on Sunday
St. Louis Cardinals

Cardinals Sign Oliver Marmol to Two-Year Extension
Thomas White

is Diagnosed with Oblique Strain
Carmen Mlodzinski

to Compete for Starting Rotation Spot
Tyler Reddick

Could Make History at COTA
Shane Van Gisbergen

Shane van Gisbergen Still the Favorite at COTA
Christopher Bell

Will Be Tough to Beat at COTA
Jacob Melton

is Returning on Sunday
AJ Allmendinger

Could Contend at COTA
Connor Zilisch

Carries Plenty of Upside for DFS at COTA
Chase Elliott

May be A Strong Contender Again at COTA
Chris Buescher

Is Nothing But Consistent at Road Courses
Ross Chastain

May Be An Underrated Competitor for the Win at COTA
William Byron

Is William Byron a Viable DFS Option for COTA?
Carson Hocevar

Needs Clean Race at COTA
Nick Suzuki

Enjoys Three-Point Night Against Capitals
Rasmus Dahlin

Collects Three Points Saturday
Kyle Larson

Could be A Decent DFS Option for COTA Lineups
Joel Kiviranta

in Concussion Protocol
Joel Eriksson Ek

Available Sunday
Ryan Blaney

Could Ryan Blaney be A Sleeper DFS Option for All Formats for COTA?
Mark Scheifele

Expected to Play Sunday
Chase Briscoe

Should DFS Players Roster Chase Briscoe at COTA?
Adam Wilsby

Exits Early Versus Stars
Gage Goncalves

Hurt in Saturday's Loss
Russell Westbrook

Off Injury Report Sunday
Kawhi Leonard

Set to Play Against Pelicans
NASCAR

Bubba Wallace Is A Favorable Value Option for COTA DFS Lineups
Ty Gibbs

Could Ty Gibbs Be A Rosterable DFS Play for COTA?
Michael McDowell

Is Michael McDowell A Favorable DFS Option for COTA?
Donovan Mitchell

to Miss Third Straight Game
Joel Embiid

Sidelined Three Games with Oblique Injury
Cooper Flagg

Remains Sidelined Sunday
Cale Makar

Scores Twice Versus Chicago
Connor McDavid

has a Three-Assist Game
Keston Hiura

Exits After Getting Hit by Pitch
Leo De Vries

Exits Early on Saturday
Kyle Stowers

is Dealing with Minor Hamstring Strain
Cody Bellinger

Dealing With Back Injury
Corbin Carroll

Likely to be Ready for Opening Day
Vladislav Namestnikov

Out Week-to-Week
Nino Niederreiter

Recovering From Surgery
Colton Parayko

Doubtful for Sunday
Zach Benson

Activated From Injured Reserve
Anthony Cirelli

a Game-Time Decision Saturday
Roope Hintz

Remains Out Saturday
Starling Marte

Royals Agree With Starling Marte
A.J. Brown

Patriots "Have Explored Trade Talks" Involving A.J. Brown
Lone'er Kavanagh

Set For UFC Mexico City Main Event
Brandon Moreno

Looks To Bounce Back
David Martinez

Set For UFC Mexico City Co-Main Event
Marlon Vera

In Dire Need Of Victory
King Green

Looks To Win Back-To-Back Fights
Daniel Zellhuber

Aims To Snap Two-Fight Skid
Felipe Bunes

Looks To Get Back In The Win Column
Édgar Cháirez

Edgar Chairez A Favorite At UFC Mexico City
George Pickens

Cowboys Not Interested in Trading George Pickens
Ashton Jeanty

Not in Line for Workhorse Role in 2026?
Anthony Richardson Sr.

Colts Give Anthony Richardson Sr. Permission to Seek a Trade
Kyler Murray

Prefers to be Released
Derek Carr

"Strong Belief" That Derek Carr is "Very Serious" About Unretiring
Andy Dalton

Is Andy Dalton Available for a Trade?
Keith Mitchell

Making The Comfortable Return to PGA National
CFB

Chandler Morris Suing NCAA for Seventh Year of Eligibility
Chris Kirk

Searching for a Spark at Cognizant Classic
Brooks Koepka

Making Third PGA Tour Start at Cognizant Classic
Mackenzie Hughes

a Steady Option at Cognizant Classic
Seamus Power

Seeking More Green in Florida
PGA

Haotong Li Back From a Break as Florida Stretch Starts
Stephan Jaeger

Trying to Put Four Rounds Together in Florida
PGA

Nico Echavarria Again Attempting to Make the Weekend
Patrick Fishburn

Looking for a Spark at Cognizant Classic
Blades Brown

Set for Cognizant Classic Debut
Michael Thorbjornsen

Looking to Bounce Back at Cognizant Classic
Maxx Crosby

Raiders Expect Maxx Crosby to Return
Billy Horschel

Looks to Improve Season at Cognizant Classic
Kyle Pitts Sr.

Falcons Place Franchise Tag on Kyle Pitts Sr.
Joe Highsmith

Returns to Defend at Cognizant Classic
Quinshon Judkins

Out of Walking Boot, Will be Ready for Training Camp
Breece Hall

Jets Will Use Franchise Tag on Breece Hall if Extension isn't Reached
Joel Dahmen

Needs Better Consistency Heading Into The Florida Swing
Daniel Berger

Looks to Improve Putting as PGA Tour Begins Its Florida Swing
Kirk Cousins

Falcons Plan to Release Kirk Cousins
Zach Ertz

Plans to Return for 14th Season
Davis Thompson

Struggling to Find Birdies as Florida Looms
Tom Kim

Not Quite Cutting It in 2026
Nicolai Hojgaard

Wants to Build Momentum from Scottsdale
Christiaan Bezuidenhout

Returns After Extended Break for Florida Event
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF