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DraftKings Lineup Picks (Week 15) - NFL DFS Advice

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 15 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 14!

 

DraftKings Quarterbacks - Week 15 DFS Picks

Matt Ryan - ATL @ TB (DK - $6,300)

Ryan is coming off a very rough three interception game, but now has a very favorable match up in his favor. He is at division rival Tampa Bay, who has the 31st DVOA against the pass, who when he played them earlier this season, he put up over 300 yards and one touchdown. This is a level of production that he should be able to match, considering the Falcons have an implied team total of 27 points, which is third highest on the slate. This game is on Monday night, so you will have to have to play on one of the expanded slates to get to him. Given the match up, he has multi-touchdown upside and a good play for GPPs.

Derek Carr - OAK vs DAL (DK - $5,700)

Carr has scored 14.5 or more DraftKings points in six of his last seven games, and is facing a weak defensive opponent. At his price, he really only needs about 16 DK points in order to reach 3x value for cash games. He is up against the Cowboys, who have the 22nd DVOA against the pass, and have shown they are very weak in the secondary. Carr will be without Amari Cooper, so pairing him with Michael Crabtree is a good idea for either format. Carr along with the Raiders haven't been consistent this season, so some DFS player might be afraid to roster him, opening the chance for lower ownership.

 

DraftKings Running Backs - Week 15 DFS Picks

Dion Lewis - RB, NE @ PIT (DK - $5,400)

Lewis has double digit rushing attempts in seven of his last last eight games, along with 11 targets in his lat four games. This game vs the Steelers has an over-under of 53 points, making it the highest of the slate, so you will want some exposure to this game. He isn't too expensive, and with the snaps he is seeing, he can pay off his salary quickly. The Steelers have the 29th DVOA against running backs in the passing game, which makes this a fantastic match up, considering his PPR value out of the backfield.

LeSean McCoy - RB, BUF vs MIA (DK - $8,400)

McCoy is in line to see plenty of work this week considering the fact the Bills are in a tough spot at quarterback. Seemingly for the past month, the Bills have a rotating cast at quarterbacks, because of injuries. McCoy had 32 carries last week, which is super high, but that was mainly due to the weather. He won't see that type of volume every week, but with Tyrod Taylor on the injury report, he could see close to it. McCoy is up against the Dolphins who have the 14th DVOA against the run.

 

DraftKings Wide Receivers - Week 15 DFS Picks

Michael Thomas - WR, NO vs NYJ (DK - $7,400)

Thomas is coming off his best game of the season, and is in an even better spot this week. He is up against the Jets who have the 27th DVOA against pass, and the 30th DVOA against WR1. This is a prime spot for him, and has massive PPR value. He has seen eight or more targets in 12 of 13 games this season, and should be able to replicate that production. He is almost a lock for 12 or more DraftKings points, and should be good for any format this week.

Keelan Cole - WR, JAX vs HOU (DK - $3,700)

Cole has 27 targets over his last five games, and for his price, he offers a ton of savings. He is up against the Texans who have the 18th DVOA against the pass, and the 27th DVOA against WR2. Cole also has touchdowns in two straight weeks, and is in a good spot to repeat that. This game may not have the highest over-under, but Cole offers some much needed savings on this full slate.

 

DraftKings Tight End - Week 15 DFS Pick

Evan Engram - TE, NYG vs PHI (DK - $5,600)

Engram has seen six or more targets in 11 of his 13 games this season, and has become the favorite receiver of Eli Manning. He is up against the Eagles, who have the 19th DVOA against tight ends, putting him in a good spot to succeed this week. If you don't want to spend all the way up to get Gronk or Kelce, he makes a good option in the middle. Good for any format this week, as he has PPR value, along with touchdown upside.

 

DraftKings Defense - Week 15 DFS Pick

Minnesota Vikings vs Cincinnati Bengals - (DK - $3,500)

The Vikings are averaging three more DraftKings points at home this season, and are now up against a Bengals team who has been very inconsistent on offense. They have seven sacks over their past four games, and two interceptions over that span. They are one of the more expensive options on the slate, so getting up to them in price price can be hard in cash games, but they are a great tournament option.

 

More Week 15 DFS Analysis

 




REAL-TIME FANTASY NEWS

Andrew Mangiapane

Labeled Day-to-Day
Brady Tkachuk

Exits Early Saturday
Rasmus Sandin

Hurt in Saturday's Win
Pierre-Luc Dubois

Sustains Upper-Body Injury Saturday
Jonathan Taylor

Back to High-End RB1 Tier with QB Returning?
Jahmyr Gibbs

a Real Threat to Bounce Back as the RB1?
Jaxon Smith-Njigba

Is Jaxon Smith-Njigba the WR1 in Dynasty Fantasy Football?
Keon Coleman

Can Keon Coleman be Dropped in Dynasty Fantasy Football?
Chris Rodriguez Jr.

Does Chris Rodriguez Jr. Fill a Need for Jacksonville?
Darnell Washington

Lacks Ties to New Coaching Staff
Mickey Moniak

has Multi-Homer Game in San Diego
Jeremy Peña

Jeremy Pena Leaves Early on Saturday With Knee Tightness
Jake Oettinger

Shuts Out the Rangers
Steven Stamkos

Scores his 40th Goal of the Year
Noah Schultz

White Sox to Promote Top Pitching Prospect Noah Schultz
Tyler Soderstrom

Slugs Two Home Runs in Win Over Mets
Adley Rutschman

Placed on 10-Day Injured List With Ankle Inflammation
George Springer

Suffers Fractured Toe on Saturday
Gabriel Moreno

Likely Headed to Injured List
Kevin Lankinen

Will Play Saturday Night
Blake Coleman

Available Against Kraken
Niklas Kokko

Makes First Career Start Saturday
Anthony Stolarz

Unavailable for Final Three Games
Roope Hintz

Not Expected to Return During Regular Season
Jacob Markstrom

Done for the Season
Markquese Bell

Facing Felony, Misdemeanor Drug Charges
Juan Soto

Could Return for Next Homestand
Corbin Carroll

Officially Back in Saturday's Lineup
Max Muncy

Hits Three Homers, Including Walk-Off Blast
Adonai Mitchell

Can Adonai Mitchell Become the Jets' WR2?
Saquon Barkley

Is Saquon Barkley Still a Safe Bet to Perform Despite His Falling Dynasty Ranking?
Michael Wilson

Varied Opinions on Michael Wilson Could Create Unique Trade Opportunities
Jake Ferguson

Accurately Priced as a Low-End TE1
Tyreek Hill

Faces Uncertain Future
Brock Bowers

Still a Top-15 Player in Dynasty Leagues Despite Injury-Plagued Season
Gavin Sheets

Goes Yard Twice, Including Walk-Off Round-Tripper
Washington Commanders

Commanders Host Omar Cooper Jr. for a Pre-Draft Visit
NFL

Makai Lemon to be a Top-20 Draft Pick This Year?
Corbin Carroll

Expected to Start on Saturday
Wyatt Langford

Forced From Friday's Game With Quad Tightness
Bijan Robinson

Falcons Pick Up Bijan Robinson's Fifth-Year Option
Kris Bubic

Dominates White Sox With 11 Strikeouts on Friday
Royce Lewis

Headed for Injured List
Mack Hollins

Can Mack Hollins Maintain a Starting Role in New England in 2026?
Clay Holmes

Removed With Hamstring Tightness
Malik Washington

Has Breakout Potential After Offseason Movement in Miami
Mike Gesicki

Is Mike Gesicki a Buy-Low Candidate After Down 2025?
Cristian Javier

Placed on 15-Day Injured List
Jayden Reed

Poised for Larger Role in Green Bay Following Offseason Movement
Matthew Golden

Does Matthew Golden Have a Clear Path to a Starting Role in His Sophomore Season?
Jaylon Tyson

Rejoins Cavaliers Lineup as Starter
Klay Thompson

Misses Friday's Game Due to Illness
Kevin Huerter

Back in Action Friday
Sam Hauser

Cleared to Play Friday
Neemias Queta

Ready to Take on Pelicans
Derrick White

Good to Go Friday
Jaylen Brown

Active on Friday
Josh Giddey

Still Out Friday
Miles McBride

Exits Knicks Lineup Friday
Mitchell Robinson

Sidelined on Friday
Norman Powell

Won't Play Against Wizards
Tyler Herro

Out on Friday
Saddiq Bey

Herbert Jones Resting Friday
Immanuel Quickley

Unavailable Friday
Julius Randle

Misses Second Straight Game
Jayson Tatum

Won't Play Friday
Jackson Chourio

Still Not Cleared to Hit
Brent Rooker

A's Place Brent Rooker on 10-Day Injured List With Oblique Strain
J.T. Realmuto

Back in Friday's Lineup
Parker Meadows

Goes on 10-Day Injured List With Broken Arm, Concussion
Carlos Ulberg

A Slight Underdog
Jiří Procházka

Jiri Prochazka Can Become UFC Champion Again
Paulo Costa

Makes his Light-Heavyweight Debut
Azamat Murzakanov

Looks To Remain Unbeaten
Josh Hokit

Looks To Remain Undefeated
Curtis Blaydes

A Favorite At UFC 327
Sam Carrick

to Miss Start of Playoffs
Alex Lyon

Questionable for Start of Postseason
Dakota Joshua

Unlikely to Return This Season
John Gibson

Exits Thursday's Game Due to Neck Problem
Miro Heiskanen

Uncertain for Playoffs
Brandon Hagel

Expected to Return Before End of Regular Season
Roman Josi

Nursing Upper-Body Injury
Trey Murphy III

Unavailable Against Celtics
Dejounte Murray

Remains Out Friday
Zion Williamson

Won't Suit Up Friday
Jalen Williams

Out on Friday
Jarrett Allen

Won't Play Against Hawks
Moritz Seider

has Five-Point Game on Thursday
Cole Caufield

Reaches 50 Goals
Tyrrell Hatton

a Steady Option at The Masters
Justin Thomas

a High-Risk, High-Reward Option at The Masters
PGA

Sungjae Im a Volatile Option at the Masters
Nicolai Hojgaard

Carrying Momentum Into The Masters
Si Woo Kim

in Strong Form Heading to The Masters
Chris Gotterup

Ready to Make His Masters Debut
Patrick Reed

Brings Momentum to The Masters
Jon Rahm

Looks Poised for His Second Green Jacket
Adam Scott

Form Points to Him Competing at Masters
Jordan Spieth

Finding Consistency Heading to Masters
Hideki Matsuyama

Trending In Right Direction For Masters
Tommy Fleetwood

a Contender if his Putter Cooperates at The Masters
Collin Morikawa

Vegas has Lost Confidence in Collin Morikawa Ahead of Masters Tournament
Ludvig Aberg

One of the Top Plays For This Week's Masters Tournament
Rory McIlroy

Set to Defend his Long-Awaited Masters Victory
Bryson DeChambeau

Looks to Finally Claim a Green Jacket
Patrick Cantlay

Needs Plenty to Go Right at Augusta
Harris English

Playing Solid Golf Heading to Masters
Sam Burns

Bouncing Back Nicely After Slow Start to 2026 Season
Corey Conners

Quietly Putting Together A Strong 2026 Season
Russell Henley

Looks to Bounce Back At Masters
Chris Duncan

Suffers Second-Round Submission Loss
Renato Moicano

Gets Back In The Win Column
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