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DraftKings Lineup Picks (Week 15) - NFL DFS Advice

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 15 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 14!

 

DraftKings Quarterbacks - Week 15 DFS Picks

Matt Ryan - ATL @ TB (DK - $6,300)

Ryan is coming off a very rough three interception game, but now has a very favorable match up in his favor. He is at division rival Tampa Bay, who has the 31st DVOA against the pass, who when he played them earlier this season, he put up over 300 yards and one touchdown. This is a level of production that he should be able to match, considering the Falcons have an implied team total of 27 points, which is third highest on the slate. This game is on Monday night, so you will have to have to play on one of the expanded slates to get to him. Given the match up, he has multi-touchdown upside and a good play for GPPs.

Derek Carr - OAK vs DAL (DK - $5,700)

Carr has scored 14.5 or more DraftKings points in six of his last seven games, and is facing a weak defensive opponent. At his price, he really only needs about 16 DK points in order to reach 3x value for cash games. He is up against the Cowboys, who have the 22nd DVOA against the pass, and have shown they are very weak in the secondary. Carr will be without Amari Cooper, so pairing him with Michael Crabtree is a good idea for either format. Carr along with the Raiders haven't been consistent this season, so some DFS player might be afraid to roster him, opening the chance for lower ownership.

 

DraftKings Running Backs - Week 15 DFS Picks

Dion Lewis - RB, NE @ PIT (DK - $5,400)

Lewis has double digit rushing attempts in seven of his last last eight games, along with 11 targets in his lat four games. This game vs the Steelers has an over-under of 53 points, making it the highest of the slate, so you will want some exposure to this game. He isn't too expensive, and with the snaps he is seeing, he can pay off his salary quickly. The Steelers have the 29th DVOA against running backs in the passing game, which makes this a fantastic match up, considering his PPR value out of the backfield.

LeSean McCoy - RB, BUF vs MIA (DK - $8,400)

McCoy is in line to see plenty of work this week considering the fact the Bills are in a tough spot at quarterback. Seemingly for the past month, the Bills have a rotating cast at quarterbacks, because of injuries. McCoy had 32 carries last week, which is super high, but that was mainly due to the weather. He won't see that type of volume every week, but with Tyrod Taylor on the injury report, he could see close to it. McCoy is up against the Dolphins who have the 14th DVOA against the run.

 

DraftKings Wide Receivers - Week 15 DFS Picks

Michael Thomas - WR, NO vs NYJ (DK - $7,400)

Thomas is coming off his best game of the season, and is in an even better spot this week. He is up against the Jets who have the 27th DVOA against pass, and the 30th DVOA against WR1. This is a prime spot for him, and has massive PPR value. He has seen eight or more targets in 12 of 13 games this season, and should be able to replicate that production. He is almost a lock for 12 or more DraftKings points, and should be good for any format this week.

Keelan Cole - WR, JAX vs HOU (DK - $3,700)

Cole has 27 targets over his last five games, and for his price, he offers a ton of savings. He is up against the Texans who have the 18th DVOA against the pass, and the 27th DVOA against WR2. Cole also has touchdowns in two straight weeks, and is in a good spot to repeat that. This game may not have the highest over-under, but Cole offers some much needed savings on this full slate.

 

DraftKings Tight End - Week 15 DFS Pick

Evan Engram - TE, NYG vs PHI (DK - $5,600)

Engram has seen six or more targets in 11 of his 13 games this season, and has become the favorite receiver of Eli Manning. He is up against the Eagles, who have the 19th DVOA against tight ends, putting him in a good spot to succeed this week. If you don't want to spend all the way up to get Gronk or Kelce, he makes a good option in the middle. Good for any format this week, as he has PPR value, along with touchdown upside.

 

DraftKings Defense - Week 15 DFS Pick

Minnesota Vikings vs Cincinnati Bengals - (DK - $3,500)

The Vikings are averaging three more DraftKings points at home this season, and are now up against a Bengals team who has been very inconsistent on offense. They have seven sacks over their past four games, and two interceptions over that span. They are one of the more expensive options on the slate, so getting up to them in price price can be hard in cash games, but they are a great tournament option.

 

More Week 15 DFS Analysis

 




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Exits Early Tuesday
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Cardinals Linked to Ty Simpson, Willing to Trade Up for him?
Jimmy Garoppolo

Rams Not Rushing Jimmy Garoppolo to Make a Decision
Harold Fannin Jr.

Taking Part in Voluntary Offseason Workouts
Jaylen Brown

Leads All Scorers With 36 Points in Game 2
Deshaun Watson

Going First in Early Offseason Drills
VJ Edgecombe

Has Historic Outing in Game 2 Win
Shai Gilgeous-Alexander

Wins Clutch Player of the Year Award
Austin Reaves

Begins Return-to-Play Protocol
Wyatt Langford

Pulled Early on Tuesday With Forearm Tightness
Luka Dončić

Luka Doncic Not Expected to Play in First-Round Series
Luke Clanton

Hoping to Find Form in New Orleans
Kevin Durant

Good to Go Tuesday
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Leaves Rehab Game With Hand Discomfort
Victor Wembanyama

Lands in Concussion Protocol, Won't Return Tuesday
Corbin Carroll

Returns to Arizona's Lineup Against White Sox
Scottie Scheffler

is Starting to Hit His Stride
Brooks Koepka

Looking for Progress in PGA Return With Partner at Zurich Classic
Matt Fitzpatrick

Looks to Share Recent Form at Zurich Classic
Jonathan Isaac

Unlikely to Play in Game 2
Mark Williams

Could Sit Again in Game 2
Grayson Allen

Questionable for Game 2
Jordan Goodwin

Iffy for Game 2
Chicago Bulls

Billy Donovan Exiting as Bulls Head Coach
Ron Harper Jr.

Available for Game 2 Against 76ers
Zack Wheeler

to Make Season Debut on Saturday
Jonathan Toews

Undecided on NHL Future
Jonathan Huberdeau

Expects to Be Ready for Training Camp
DAL

Nathan Bastian Not Expected to Play Before Round 2
Roope Hintz

Doubtful for Game 4
Adam Henrique

Won't Play in Game 2 Against Ducks
Victor Hedman

Doubtful to Play in Round 1
Charle-Edouard D'Astous

Unavailable Tuesday
Dalton Kincaid

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Alvin Kamara

Remains a Top Dynasty Sell Candidate Ahead of NFL Draft
Jordan James

Offers Sneaky Buy-Low Potential Ahead of NFL Draft
Jaylen Waddle

a Top Buy-Low Candidate Heading into First Season in Denver
Josh Downs

a Top Buy-Low Candidate Ahead of NFL Draft
Mike Evans

a Sneaky Dynasty Buy Candidate Ahead of NFL Draft?
Tyler Bass

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Ronald Acuna Jr. Back in Leadoff Spot on Tuesday After Injury Scare
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Patriots Targeting Eli Stowers in the NFL Draft?
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Jeremiyah Love Could Unlock Commanders Offense
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Activated From Injured List on Tuesday
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Continues Strong Start With 12-Strikeout Performance
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Placed on 15-Day Injured List with Shoulder Inflammation
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Records Two Assists in Losing Effort
Brock Faber

Bags Two Goals in Monday's Defeat
Wyatt Johnston

Notches Two Goals in Game 2 Win
Troy Terry

Has Special Playoffs Debut
Dan Vladar

Leads Flyers to Victory With 27-Save Shutout
Yakov Trenin

Suffers Upper-Body Injury in Game 2
Rasmus Sandin

to Miss Start of 2026-27
CJ McCollum

Shines at MSG in Game 2
Max Muncy

With Another Two-Homer Game, Becoming Must-Add Off Waiver Wire
Ronald Acuña Jr.

Ronald Acuna Jr. Day-to-Day After Being Hit on the Hand on Monday
Mick Abel

Injury Described as "Not Too Serious"
Brendan Donovan

Mariners Place Brendan Donovan on Injured List With Groin Strain
Sonny Gray

Heading to the Injured List With Hamstring Injury
Edwin Díaz

Edwin Diaz Expected to Miss Around Three Months
Edwin Uceta

Shut Down for 2-3 Weeks; Is he Still Stash-Worthy?
Charle-Edouard D'Astous

Doubtful for Game 2
Brad Keller

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Edwin Díaz

Edwin Diaz Placed on 15-Day Injured List with Elbow Injury
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Kyle Larson

Finishes as the Runner-Up at Kansas
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Denny Hamlin

Leads the Most Laps at Kansas but Misses Out on Victory
Christopher Bell

Falls Out of Contention for Kansas Victory on Final Restart
Mike Malott

Scores Third-Round TKO Win
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Leaves Monday's Start Early With Hamstring Tightness
Gilbert Burns

Retires After UFC Winnipeg Loss
Charles Jourdain

Extends Winning Streak
Kyler Phillips

Drops Decision At UFC Winnipeg
Mandel Nallo

Suffers First-Round TKO Loss In His UFC Debut
Jai Herbert

Scores First-Round TKO Win
Karine Silva

Gets Dominated at UFC Winnipeg
Jasmine Jasudavicius

Dominates Karine Silva
Kyle Larson

Should not be Underestimated for the Win at Kansas
Denny Hamlin

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Christoper Bell Should Contend for First Win at Kansas
Tyler Reddick

Fastest in Practice and Qualifying for Kansas Race
Ryan Blaney

Could Score another Top-10 Finish at Kansas
Ty Gibbs

Poised to Continue Hot Streak at Kansas
Chris Buescher

Always Consistent, Has Speed Heading Into Kansas
William Byron

is A Solid DFS Option for Kansas Lineups
Carson Hocevar

Poised for Career-Best Run at Kansas
Chase Briscoe

Is Chase Briscoe Worth Rostering for DFS at Kansas?
Chase Elliott

Is A Favorable DFS Option for Kansas Lineups
Joey Logano

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NASCAR

Bubba Wallace is A Favorable Driver to Consider for Kansas Lineups
Ross Chastain

Is Ross Chastain A Worthy DFS Option for Kansas?
Brad Keselowski

Could Brad Keselowski be A Sneaky DFS Option for Kansas?
Daniel Suarez

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Mike Malott

A Favorite At UFC Winnipeg
Gilbert Burns

Set For UFC Winnipeg Main Event
Kyler Phillips

Set UFC Winnipeg Co-Main Event
Charles Jourdain

Looks To Extend His Win Streak
Jai Herbert

An Underdog At UFC Winnipeg
Mandel Nallo

Set For His UFC Debut
Karine Silva

Looks To Get Back In The Win Column
Jasmine Jasudavicius

Looks To Bounce Back
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