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DraftKings Lineup Picks (Week 15) - NFL DFS Advice

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 15 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 14!

 

DraftKings Quarterbacks - Week 15 DFS Picks

Matt Ryan - ATL @ TB (DK - $6,300)

Ryan is coming off a very rough three interception game, but now has a very favorable match up in his favor. He is at division rival Tampa Bay, who has the 31st DVOA against the pass, who when he played them earlier this season, he put up over 300 yards and one touchdown. This is a level of production that he should be able to match, considering the Falcons have an implied team total of 27 points, which is third highest on the slate. This game is on Monday night, so you will have to have to play on one of the expanded slates to get to him. Given the match up, he has multi-touchdown upside and a good play for GPPs.

Derek Carr - OAK vs DAL (DK - $5,700)

Carr has scored 14.5 or more DraftKings points in six of his last seven games, and is facing a weak defensive opponent. At his price, he really only needs about 16 DK points in order to reach 3x value for cash games. He is up against the Cowboys, who have the 22nd DVOA against the pass, and have shown they are very weak in the secondary. Carr will be without Amari Cooper, so pairing him with Michael Crabtree is a good idea for either format. Carr along with the Raiders haven't been consistent this season, so some DFS player might be afraid to roster him, opening the chance for lower ownership.

 

DraftKings Running Backs - Week 15 DFS Picks

Dion Lewis - RB, NE @ PIT (DK - $5,400)

Lewis has double digit rushing attempts in seven of his last last eight games, along with 11 targets in his lat four games. This game vs the Steelers has an over-under of 53 points, making it the highest of the slate, so you will want some exposure to this game. He isn't too expensive, and with the snaps he is seeing, he can pay off his salary quickly. The Steelers have the 29th DVOA against running backs in the passing game, which makes this a fantastic match up, considering his PPR value out of the backfield.

LeSean McCoy - RB, BUF vs MIA (DK - $8,400)

McCoy is in line to see plenty of work this week considering the fact the Bills are in a tough spot at quarterback. Seemingly for the past month, the Bills have a rotating cast at quarterbacks, because of injuries. McCoy had 32 carries last week, which is super high, but that was mainly due to the weather. He won't see that type of volume every week, but with Tyrod Taylor on the injury report, he could see close to it. McCoy is up against the Dolphins who have the 14th DVOA against the run.

 

DraftKings Wide Receivers - Week 15 DFS Picks

Michael Thomas - WR, NO vs NYJ (DK - $7,400)

Thomas is coming off his best game of the season, and is in an even better spot this week. He is up against the Jets who have the 27th DVOA against pass, and the 30th DVOA against WR1. This is a prime spot for him, and has massive PPR value. He has seen eight or more targets in 12 of 13 games this season, and should be able to replicate that production. He is almost a lock for 12 or more DraftKings points, and should be good for any format this week.

Keelan Cole - WR, JAX vs HOU (DK - $3,700)

Cole has 27 targets over his last five games, and for his price, he offers a ton of savings. He is up against the Texans who have the 18th DVOA against the pass, and the 27th DVOA against WR2. Cole also has touchdowns in two straight weeks, and is in a good spot to repeat that. This game may not have the highest over-under, but Cole offers some much needed savings on this full slate.

 

DraftKings Tight End - Week 15 DFS Pick

Evan Engram - TE, NYG vs PHI (DK - $5,600)

Engram has seen six or more targets in 11 of his 13 games this season, and has become the favorite receiver of Eli Manning. He is up against the Eagles, who have the 19th DVOA against tight ends, putting him in a good spot to succeed this week. If you don't want to spend all the way up to get Gronk or Kelce, he makes a good option in the middle. Good for any format this week, as he has PPR value, along with touchdown upside.

 

DraftKings Defense - Week 15 DFS Pick

Minnesota Vikings vs Cincinnati Bengals - (DK - $3,500)

The Vikings are averaging three more DraftKings points at home this season, and are now up against a Bengals team who has been very inconsistent on offense. They have seven sacks over their past four games, and two interceptions over that span. They are one of the more expensive options on the slate, so getting up to them in price price can be hard in cash games, but they are a great tournament option.

 

More Week 15 DFS Analysis

 




REAL-TIME FANTASY NEWS

Lucas Erceg

Throwing Off the Mound in Camp
Justin Foscue

to Work in the Outfield This Spring
Julian Aguiar

Competing for Final Rotation Spot in Cincy
Jared Triolo

a Front-Runner to Win Third Base Job?
Yency Almonte

Dodgers Sign Yency Almonte to Minor-League Deal
Janson Junk

Diagnosed With Grade 1 Ankle Sprain
Stephen Curry

to Be Re-Evaluated In 10 Days
Jordan Westburg

More Details Coming Soon on Jordan Westburg's Injuries
Grayson Allen

Sidelined Thursday Vs. Spurs
Milwaukee Brewers

Brewers Give Pat Murphy a New Three-Year Deal
Ajay Mitchell

Out At Least One More Week
Shane Bieber

"Feeling Good," Throwing Up to 120 Feet
Cedric Coward

Out Versus Utah
Santi Aldama

Sidelined Again on Friday
Shota Imanaga

Showing Increased Velocity With Better Health
Jalen Williams

to Be Re-Evaluated In Two Weeks
Carson Whisenhunt

Velocity Up This Spring
Shai Gilgeous-Alexander

to Miss At Least One More Week
Jusuf Nurkić

Jusuf Nurkic Won't Face Memphis on Friday Night
Lane Thomas

Says he's Fully Healthy
Keyonte George

Not Ready to Return on Friday
Sandro Mamukelashvili

Collin Murray-Boyles, Sandro Mamukelashvili Cleared To Play Thursday
Randy Vásquez

Randy Vasquez has "Inside Track" on Rotation Spot
Kutter Crawford

a Candidate to Start Season on Injured List
Noah Clowney

is Ready to Play on Thursday
Michael Porter Jr.

is Returning on Thursday
Jalen Smith

is Cleared for Thursday's Game
Aaron Nesmith

to Play on Thursday
Tre Jones

to Suit Up on Thursday
Coby Mayo

Might Have an Opening at Third Base
Josh Giddey

is Available for Thursday's Contest
OG Anunoby

is Cleared for Thursday's Game
Seranthony Domínguez

Seranthony Dominguez Named White Sox's Closer
T.J. McConnell

Out of Action Versus Wizards
Gavin Williams

Mechanical Adjustment Helped Gavin Williams Break Out in 2025
Stephen Curry

Sidelined Again on Thursday
Malik Monk

Set to Return on Thursday
Rhett Lowder

Looking "Very Polished" in Camp
Christian Encarnacion-Strand

Could Play in Games Next Week
Russell Westbrook

Set to Suit Up Thursday
Moisés Ballesteros

Moises Ballesteros Should be in Camp This Weekend
Matthew Boyd

Could Be a Candidate to Regress in 2026
Logan Cooley

Sheds Non-Contact Jersey
Maxwell Crozier

to Miss 10 Weeks After Surgery
Kirill Marchenko

Dealing With Lower-Body Injury
Petr Mrazek

Undergoes Season-Ending Surgery
Victor Hedman

Suffers Lower-Body Injury
Sidney Crosby

Considered Day-to-Day
Rashee Rice

Accused of Assault by Long-Time Girlfriend
Ben Griffin

Looking to Return to Top Form at Riviera
Keegan Bradley

Looking to Build Momentum at Riviera
J.J. Spaun

Putting a Major Concern at Riviera
Sepp Straka

May Have Tough Time at The Genesis Invitational
Shane Lowry

Trending Up Entering the Genesis Invitational
Justin Rose

Off Most Radars at The Genesis Invitational
Robert MacIntyre

a Long Hitter to Watch at Riviera Country Club
Jake Knapp

Red-Hot Heading to Riviera
Min Woo Lee

Attempts to Build Momentum After Pebble Beach
Harry Hall

an Unknown for The Genesis Invitational
Matt Fitzpatrick

Has Favorable Path to Success at Riviera This Week
Wyndham Clark

Not Likely to Contend at Genesis Invitational
Ludvig Aberg

Might Find the Genesis Invitational More Challenging
Harris English

Carries Strong Form to Riviera
Patrick Cantlay

Eyes Another Strong Week at The Genesis Invitational
Daniel Berger

Needs Short Game to Show Up at Riviera
Sam Burns

Hopes Return to Form Continues at Riviera
Collin Morikawa

Riding Wave of Victory Into Riviera
Hideki Matsuyama

Looks to Have Repeat Success at The Genesis Invitational
Scottie Scheffler

Looks to Find Paydirt at Riviera
Xander Schauffele

Rounding into Form Before Genesis Invitational
Morgan Rielly

Available After Olympic Break
Charlie Lindgren

Practices Fully Tuesday
John Carlson

Ready to Rock After Olympics
Radek Faksa

Unavailable Against Team Canada
Anton Lundell

Good to Go Wednesday
Brandon Bussi

Earns Three-Year Extension
SJ

Sharks Terminating Jeff Skinner's Contract
Mike Evans

Will Return in 2026
Kenneth Walker III

Seahawks Not Expected to Use Franchise Tag on Kenneth Walker III
Bucky Irving

Undergoes Offseason Shoulder Surgery
Tyreek Hill

Says he Will Play in 2026
Joey Logano

Finishes Third in the 2026 Daytona 500
Ricky Stenhouse Jr

. Finishes as the Runner-Up in the Daytona 500
Chase Elliott

Falls Short of His First Daytona 500 Victory Again
Brad Keselowski

Ends Daytona 500 With a Top-Five Finish
Tyler Reddick

Wins the Daytona 500 for the First Time with 23XI Racing
Tyreek Hill

Released by Dolphins
Joey Logano

Should DFS Players Roster Joey Logano At Daytona?
Ryan Blaney

Is Ryan Blaney Worth Rostering for DFS at Daytona?
Chase Briscoe

May Not be Worth DFS Consideration for Daytona
Chase Elliott

Is Chase Elliott Worth Rostering At Daytona This Week For DFS?
Austin Cindric

May Be Worth Rostering At Daytona
Cleveland Browns

Browns to Spend Top Draft Picks on Receiver or Offensive Lineman?
Brad Keselowski

Is Brad Keselowski Worth Rostering for Daytona Lineups?
Tyler Reddick

May be A Solid and Sneaky Pick for Daytona Lineups
Alex Bowman

is A Highly Favorable Mid-Tier Option for Daytona
Ross Chastain

Could be A Top DFS Scorer for Daytona
Justin Allgaier

is One of the Safest DFS Options for Daytona
Tim Stützle

Tim Stutzle Matches Team Germany Record With Third Goal
Jack Eichel

Off to Hot Start in Olympics
OTT

Mads Sogaard Injured Saturday
NASCAR

Christoper Bell Emerging As One of The Best at Daytona
William Byron

Trying for Third Straight Daytona 500 Victory
Kyle Larson

Has Never Posted a Top-Five Finish at Daytona
Denny Hamlin

Is Denny Hamlin Overrated at Daytona?
Chris Buescher

an Easy DFS Pick for the Daytona 500
Kyle Busch

on Pole, Still Searching for Elusive Daytona 500 Victory
Lucas Raymond

Ties Team Sweden Record With Three Points Saturday
Anton Lundell

Battling Illness
Kevin Fiala

Out for the Season
RANKINGS
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