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DraftKings Lineup Picks (Week 15) - NFL DFS Advice

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 15 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 14!

 

DraftKings Quarterbacks - Week 15 DFS Picks

Matt Ryan - ATL @ TB (DK - $6,300)

Ryan is coming off a very rough three interception game, but now has a very favorable match up in his favor. He is at division rival Tampa Bay, who has the 31st DVOA against the pass, who when he played them earlier this season, he put up over 300 yards and one touchdown. This is a level of production that he should be able to match, considering the Falcons have an implied team total of 27 points, which is third highest on the slate. This game is on Monday night, so you will have to have to play on one of the expanded slates to get to him. Given the match up, he has multi-touchdown upside and a good play for GPPs.

Derek Carr - OAK vs DAL (DK - $5,700)

Carr has scored 14.5 or more DraftKings points in six of his last seven games, and is facing a weak defensive opponent. At his price, he really only needs about 16 DK points in order to reach 3x value for cash games. He is up against the Cowboys, who have the 22nd DVOA against the pass, and have shown they are very weak in the secondary. Carr will be without Amari Cooper, so pairing him with Michael Crabtree is a good idea for either format. Carr along with the Raiders haven't been consistent this season, so some DFS player might be afraid to roster him, opening the chance for lower ownership.

 

DraftKings Running Backs - Week 15 DFS Picks

Dion Lewis - RB, NE @ PIT (DK - $5,400)

Lewis has double digit rushing attempts in seven of his last last eight games, along with 11 targets in his lat four games. This game vs the Steelers has an over-under of 53 points, making it the highest of the slate, so you will want some exposure to this game. He isn't too expensive, and with the snaps he is seeing, he can pay off his salary quickly. The Steelers have the 29th DVOA against running backs in the passing game, which makes this a fantastic match up, considering his PPR value out of the backfield.

LeSean McCoy - RB, BUF vs MIA (DK - $8,400)

McCoy is in line to see plenty of work this week considering the fact the Bills are in a tough spot at quarterback. Seemingly for the past month, the Bills have a rotating cast at quarterbacks, because of injuries. McCoy had 32 carries last week, which is super high, but that was mainly due to the weather. He won't see that type of volume every week, but with Tyrod Taylor on the injury report, he could see close to it. McCoy is up against the Dolphins who have the 14th DVOA against the run.

 

DraftKings Wide Receivers - Week 15 DFS Picks

Michael Thomas - WR, NO vs NYJ (DK - $7,400)

Thomas is coming off his best game of the season, and is in an even better spot this week. He is up against the Jets who have the 27th DVOA against pass, and the 30th DVOA against WR1. This is a prime spot for him, and has massive PPR value. He has seen eight or more targets in 12 of 13 games this season, and should be able to replicate that production. He is almost a lock for 12 or more DraftKings points, and should be good for any format this week.

Keelan Cole - WR, JAX vs HOU (DK - $3,700)

Cole has 27 targets over his last five games, and for his price, he offers a ton of savings. He is up against the Texans who have the 18th DVOA against the pass, and the 27th DVOA against WR2. Cole also has touchdowns in two straight weeks, and is in a good spot to repeat that. This game may not have the highest over-under, but Cole offers some much needed savings on this full slate.

 

DraftKings Tight End - Week 15 DFS Pick

Evan Engram - TE, NYG vs PHI (DK - $5,600)

Engram has seen six or more targets in 11 of his 13 games this season, and has become the favorite receiver of Eli Manning. He is up against the Eagles, who have the 19th DVOA against tight ends, putting him in a good spot to succeed this week. If you don't want to spend all the way up to get Gronk or Kelce, he makes a good option in the middle. Good for any format this week, as he has PPR value, along with touchdown upside.

 

DraftKings Defense - Week 15 DFS Pick

Minnesota Vikings vs Cincinnati Bengals - (DK - $3,500)

The Vikings are averaging three more DraftKings points at home this season, and are now up against a Bengals team who has been very inconsistent on offense. They have seven sacks over their past four games, and two interceptions over that span. They are one of the more expensive options on the slate, so getting up to them in price price can be hard in cash games, but they are a great tournament option.

 

More Week 15 DFS Analysis

 




REAL-TIME FANTASY NEWS

Kirill Marchenko

a Game-Time Call Wednesday
Sam Bennett

Anton Lundell Available for Panthers Wednesday
Bobby Portis

Out With Hip Contusion
Chet Holmgren

Ruled Out Wednesday
Nick Bjugstad

Devils Add Nick Bjugstad With Trade
Ivica Zubac

Unavailable on Wednesday
Artemi Panarin

Traded to Kings, Signs Two-Year Extension
Jock Landale

Redirected to Atlanta in New Trade
Lonzo Ball

Traded to Utah, Expected to be Waived
NBA

Chris Paul Traded to Toronto, Will Not Play For Team
Coby White

Sent to Charlotte in Trade
Shai Gilgeous-Alexander

Out Until at Least the All-Star Break
Jared McCain

Moving From Philadelphia to Oklahoma City
Khris Middleton

Landing in Dallas
Anthony Davis

Traded to the Wizards
CFB

Sam Leavitt to be Limited In Spring Practice
Jordan Love

Avoids Offseason Surgery
Bligh Madris

Cardinals Sign Bligh Madris to Minor-League Deal
Mickey Gasper

Red Sox Claim Mickey Gasper Off Waivers From Nationals
Yanquiel Fernández

Yankees Claim Yanquiel Fernandez Off Waivers From Rockies
Michael Fulmer

Signs Minor-League Deal With Giants
Grant Taylor

to Transition Back to Starting Role in 2027?
Framber Valdez

Pirates Emerging as Suitor for Framber Valdez
Tayler Scott

Signs Minor-League Deal With Braves
Max Clark

Receives Invite to Big-League Camp
Kevin McGonigle

Tigers Invite Shortstop Prospect Kevin McGonigle to Spring Training
Marcell Ozuna

Pirates Showing Interest in Marcell Ozuna
Brandon Drury

Royals Sign Brandon Drury to Minor-League Deal
Rhett Lowder

Could be Mid-Rotation Starter For Reds in 2026
Gunnar Henderson

Works on Speed in Offseason
Matt Fitzpatrick

Back in Action at WM Phoenix Open
Sahith Theegala

Riding Hot Start Into WM Phoenix Open
J.J. Spaun

Looks to Regain Form at WM Phoenix Open
Viktor Hovland

a Volatile Option at WM Phoenix Open
Rasmus Hojgaard

Aims to Build on Solid Start to 2026
Brian Harman

Looks to Find Form at WM Phoenix Open
Daniel Berger

Has the Tools to Go One Step Higher at Scottsdale
Max Greyserman

Searching for Consistency at WM Phoenix Open
Jake Knapp

Wants Revenge at WM Phoenix Open
CFB

Joey Aguilar Granted Temporary Restraining Order Against NCAA
Joel Dahmen

Carrying Momentum Into WM Phoenix Open
Corey Conners

Unlikely to Contend at Scottsdale
Mathew Barzal

Plays Key Role in Comeback Victory
Sepp Straka

Seeks a Rebound After The American Express
Sebastian Aho

Bags Three Points in Tuesday's Win
Jordan Spieth

Healthy Heading to WM Phoenix Open
Darren Raddysh

Extends Goal Streak to Five Games
Keith Mitchell

Building Momentum for Event in Scottsdale
Nikita Kucherov

Posts Second Straight Four-Point Game
Travis Konecny

Extends Multi-Point Streak Tuesday
Ramón Urías

Red Sox Have "Lukewarm" Interest in Ramon Urias
Tom Hoge

The Tom Hoge Roller Coaster Heads to Scottsdale for WM Phoenix Open
Elvis Merzlikins

Earns First Shutout of the Season
Josiah Gray

Could Earn Opening Day Start
Filip Chytil

Dealing With Migranes
Luis García Jr.

Luis Garcia Jr. a Candidate to Play First Base?
Rickie Fowler

Worth a Look at WM Phoenix Open
Jakob Marsee

Marlins Have Approached Jakob Marsee About Contract Extension
Jeremy Sochan

Out Wednesday
Jordan Leasure

was Almost Traded to Red Sox
Mike Conley

Not Expected to Remain in Chicago
Freddy Peralta

Carson Benge was Not Considered in Trade With Brewers
Dennis Schröder

Dennis Schroder, Keon Ellis Available for Cavaliers Wednesday
De'Andre Hunter

Available for Kings Debut Wednesday
Josh Hart

Hurt in Blowout Win
Seattle Mariners

Ryan Sloan a Budding Arm in Seattle's System
LeBron James

Expects to Stay With Lakers Until End of Season
Mick Abel

Can Mick Abel Take the Next Step in the Major Leagues?
Derrick Jones Jr.

Off the Injury Report
Scotty Pippen Jr.

Tagged as Doubtful for Wednesday
Santi Aldama

Uncertain to Suit Up Wednesday
Domantas Sabonis

Questionable for Wednesday
Nick Foligno

Set to Return Wednesday
Dante Fabbro

Returns From Six-Game Absence
Kirill Marchenko

Out Tuesday
Bryan Rust

Returns to Penguins Lineup
Jack Hughes

Misses Second Straight Game
Ukko-Pekka Luukkonen

Out for Olympics
Anthony Cirelli

to Miss Olympics
Xander Schauffele

Making Second Appearance at Phoenix Open
Collin Morikawa

Needs a Bounce-Back at Waste Management Phoenix Open
Hideki Matsuyama

Has a Shot to Challenge at the Waste Management Phoenix Open
Max Homa

Playing Well Heading to Waste Management Phoenix Open
Ben Griffin

Will Need to Find Approach Game to Compete in Phoenix
Michael Penix Jr.

Matt Ryan Not Committing to Michael Penix Jr. as the Starting QB
NASCAR

Billy Horschel Unlikely to Right the Ship in Phoenix
Nick Schmaltz

Leads Mammoth to Victory Monday
Roman Josi

Has Four Assists in Huge Comeback Win
Quinn Hughes

Records Hat Trick of Assists
Matthew Stafford

Doesn't Need Offseason Back Surgery
CFB

Joey Aguilar Files New Lawsuit Against NCAA Seeking Sixth Year of Eligibility
Davante Adams

Expected to Return to Rams in 2026
Los Angeles Rams

Rams Sign Sean McVay, Les Snead to Contract Extensions
Diego Lopes

Outclassed At UFC 325
Alexander Volkanovski

Dominates Diego Lopes
Dan Hooker

Stopped In The Second Round
Benoît Saint Denis

Benoit Saint Denis Extends His Win Streak
Rafael Fiziev

Suffers Second-Round TKO Loss
MMA

Maurício Ruffy Gets Back In The Win Column
San Francisco 49ers

49ers Set to Name Raheem Morris Their Defensive Coordinator
Las Vegas Raiders

Raiders Close to Naming Klint Kubiak the Next Head Coach
Arizona Cardinals

Cardinals Finalizing Deal to Make Mike LaFleur the Next Head Coach
CFB

Gus Malzahn Retiring from Coaching
Breece Hall

Jets Want to Re-Sign Breece Hall, Could Use Franchise Tag
Diego Lopes

An Underdog At UFC 325
Alexander Volkanovski

Set For UFC 325 Main Event
Benoît Saint Denis

Benoit Saint Denis Looks To Extend His Win Streak
Dan Hooker

Set For UFC 325 Co-Main Event
Mauricio Ruffy

Looks To Get Back In The Win Column
Rafael Fiziev

Returns At UFC 325
CFB

Texas Lands Wake Forest Transfer Sterling Berkhalter
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