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DraftKings Lineup Picks (Week 15) - NFL DFS Advice

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 15 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 14!

 

DraftKings Quarterbacks - Week 15 DFS Picks

Matt Ryan - ATL @ TB (DK - $6,300)

Ryan is coming off a very rough three interception game, but now has a very favorable match up in his favor. He is at division rival Tampa Bay, who has the 31st DVOA against the pass, who when he played them earlier this season, he put up over 300 yards and one touchdown. This is a level of production that he should be able to match, considering the Falcons have an implied team total of 27 points, which is third highest on the slate. This game is on Monday night, so you will have to have to play on one of the expanded slates to get to him. Given the match up, he has multi-touchdown upside and a good play for GPPs.

Derek Carr - OAK vs DAL (DK - $5,700)

Carr has scored 14.5 or more DraftKings points in six of his last seven games, and is facing a weak defensive opponent. At his price, he really only needs about 16 DK points in order to reach 3x value for cash games. He is up against the Cowboys, who have the 22nd DVOA against the pass, and have shown they are very weak in the secondary. Carr will be without Amari Cooper, so pairing him with Michael Crabtree is a good idea for either format. Carr along with the Raiders haven't been consistent this season, so some DFS player might be afraid to roster him, opening the chance for lower ownership.

 

DraftKings Running Backs - Week 15 DFS Picks

Dion Lewis - RB, NE @ PIT (DK - $5,400)

Lewis has double digit rushing attempts in seven of his last last eight games, along with 11 targets in his lat four games. This game vs the Steelers has an over-under of 53 points, making it the highest of the slate, so you will want some exposure to this game. He isn't too expensive, and with the snaps he is seeing, he can pay off his salary quickly. The Steelers have the 29th DVOA against running backs in the passing game, which makes this a fantastic match up, considering his PPR value out of the backfield.

LeSean McCoy - RB, BUF vs MIA (DK - $8,400)

McCoy is in line to see plenty of work this week considering the fact the Bills are in a tough spot at quarterback. Seemingly for the past month, the Bills have a rotating cast at quarterbacks, because of injuries. McCoy had 32 carries last week, which is super high, but that was mainly due to the weather. He won't see that type of volume every week, but with Tyrod Taylor on the injury report, he could see close to it. McCoy is up against the Dolphins who have the 14th DVOA against the run.

 

DraftKings Wide Receivers - Week 15 DFS Picks

Michael Thomas - WR, NO vs NYJ (DK - $7,400)

Thomas is coming off his best game of the season, and is in an even better spot this week. He is up against the Jets who have the 27th DVOA against pass, and the 30th DVOA against WR1. This is a prime spot for him, and has massive PPR value. He has seen eight or more targets in 12 of 13 games this season, and should be able to replicate that production. He is almost a lock for 12 or more DraftKings points, and should be good for any format this week.

Keelan Cole - WR, JAX vs HOU (DK - $3,700)

Cole has 27 targets over his last five games, and for his price, he offers a ton of savings. He is up against the Texans who have the 18th DVOA against the pass, and the 27th DVOA against WR2. Cole also has touchdowns in two straight weeks, and is in a good spot to repeat that. This game may not have the highest over-under, but Cole offers some much needed savings on this full slate.

 

DraftKings Tight End - Week 15 DFS Pick

Evan Engram - TE, NYG vs PHI (DK - $5,600)

Engram has seen six or more targets in 11 of his 13 games this season, and has become the favorite receiver of Eli Manning. He is up against the Eagles, who have the 19th DVOA against tight ends, putting him in a good spot to succeed this week. If you don't want to spend all the way up to get Gronk or Kelce, he makes a good option in the middle. Good for any format this week, as he has PPR value, along with touchdown upside.

 

DraftKings Defense - Week 15 DFS Pick

Minnesota Vikings vs Cincinnati Bengals - (DK - $3,500)

The Vikings are averaging three more DraftKings points at home this season, and are now up against a Bengals team who has been very inconsistent on offense. They have seven sacks over their past four games, and two interceptions over that span. They are one of the more expensive options on the slate, so getting up to them in price price can be hard in cash games, but they are a great tournament option.

 

More Week 15 DFS Analysis

 




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Hurston Waldrep

is Dealing with Elbow Discomfort
Nolan Gorman

JJ Wetherholt is at Second Base, Nolan Gorman Getting Reps at Third
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Colt Keith

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Carlos Narvaez to Remain Boston's Starting Catcher
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Ryan Blaney

Is Ryan Blaney Worth Rostering for DFS at Daytona?
Chase Briscoe

May Not be Worth DFS Consideration for Daytona
Chase Elliott

Is Chase Elliott Worth Rostering At Daytona This Week For DFS?
Austin Cindric

May Be Worth Rostering At Daytona
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Brad Keselowski

Is Brad Keselowski Worth Rostering for Daytona Lineups?
Tyler Reddick

May be A Solid and Sneaky Pick for Daytona Lineups
Alex Bowman

is A Highly Favorable Mid-Tier Option for Daytona
Ross Chastain

Could be A Top DFS Scorer for Daytona
Justin Allgaier

is One of the Safest DFS Options for Daytona
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Tim Stützle

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Karl-Anthony Towns

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Kyle Larson

Has Never Posted a Top-Five Finish at Daytona
Denny Hamlin

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Chris Buescher

an Easy DFS Pick for the Daytona 500
Kyle Busch

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Jimmie Johnson

Still Has More Left in The Tank
Giannis Antetokounmpo

Feeling "100 Percent"
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Battling Illness
Kevin Fiala

Out for the Season
Riley Minix

Signs Two-Way Deal With Cavaliers
Luka Dončić

Luka Doncic Likely Available for All-Star Game
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Chris Paul Retires From Basketball
Zach LaVine

to Undergo Season-Ending Hand Surgery
David Pastrnak

Gets Off the Mark at Olympics
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Pots Another Goal Friday
Kevin Fiala

Stretchered Off Against Canada
Aaron Rodgers

Likely to Return to Steelers?
Terry McLaurin

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Deandre Ayton

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Posts Historic Triple-Double in Win
Ja Morant

Still Without Clear Return Date
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Luka Doncic Expected Back After All-Star Break
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Exits Early with Foot Strain
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Leaves Game with Ankle Issue
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Josh Morrissey

Hurt in Olympic Opener
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Deni Avdija

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Alexandre Sarr

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Naji Marshall

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Trinidad Chambliss Eligible for 2026 Season
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BYU's Parker Kingston Charged with Felony Rape
Cameron Young

Looking for Pebble Beach Success
J.J. Spaun

Looks to Turn Things Around at Pebble Beach
Collin Morikawa

Eyes Turnaround at Pebble Beach
Jake Knapp

Brings Hot Form to Pebble Beach
Nick Taylor

in Good Form Going into Pebble Beach Event
Viktor Hovland

Carrying Momentum Into Pebble Beach
Tommy Fleetwood

Set for 2026 PGA Tour Debut at Pebble Beach
Harris English

Looks to Build on Steady Form at Pebble Beach
Justin Rose

Tuned in for AT&T Pebble Beach Pro-Am
Keegan Bradley

a Boom-or-Bust Play at Pebble Beach
Maverick McNealy

Playing Well with Pebble Beach Looming
Russell Henley

Carries Momentum to Pebble Beach
Shane Lowry

Makes 2026 PGA Tour Debut at Pebble Beach
Michael Kim

Putting Well with Pebble Beach on the Horizon
Billy Horschel

a Little Rattled After Consecutive Missed Cuts
Ben Griffin

Solid But Not Spectacular Early in 2026
Wyndham Clark

Has Question Marks Heading to Pebble Beach
Daniel Berger

Heating Up at the Right Time for Pebble Beach
Jordan Spieth

Looking For a Return to Form at Pebble Beach
Juuse Saros

Starting Wednesday
William Nylander

Iffy for Olympic Opener
Martin Necas

Ready for Thursday
Drake Maye

Says his Shoulder Injury was Significant
Xander Schauffele

Trying to Get the Motor Going at Pebble Beach
Hideki Matsuyama

Trying to Overcome Sunday Collapse
RANKINGS
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