X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

DraftKings Lineup Picks (Week 10) - NFL DFS Advice

RotoBallers, welcome to Week 10 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 10 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 10!

 

DraftKings Quarterbacks - Week 10 DFS Picks

Matthew Stafford - DET vs CLE (DK $6,800)

Stafford is looking like one of the best options at quarterback this week, and coming off a big game. He played on Monday night, so his price wasn't adjusted for his performance last week. This is somewhat minor, but still and edge to be gained and we want to jump on it. Stafford has put up 300 yards or more in three straight games, and has seven touchdowns in his last four games. Really strong numbers from the highest paid quarterback. With his price and recent performance you could use him in either cash or GPPs, since he has a favorable match up. Speaking of his opponent, let's talk about the Browns! The Browns have the 28th DVOA against the pass, and simply cannot not stop the ball via the air. You want to find them every week, and target against them. Get exposure to them by either the quarterback or the receivers. The Browns are actually very good vs the run, so nearly all of the Lions offense will come from Stafford.

Ryan Fitzpatrick - TB vs NYJ (DK $4,900)

If you are looking for a cheap quarterback that has a solid match up, key in on Fitzpatrick this week. Not only is this a nice revenge game for him, going up against his former team, but the Jets have the 21st DVOA against the pass, and haven't looked strong on defense. For his price, he really only needs to put up 14.7 DraftKings points in order to reach 3x value, which is what you are looking for in cash games. Anything more than that, and will make a good tournament play. Stacking him with someone like DeSean Jackson, makes a good play since he has plenty of touchdown upside.

 

DraftKings Running Backs - Week 10 DFS Picks

LeSean McCoy - BUF vs. NO (DK $8,300)

Seems like few people are talking about McCoy this week, and might be due to the fact he had such a bad showing last Thursday night. If no one is going to be rostering him, he makes a great tournament play, since he has multi touchdown upside, along with seeing plenty of targets out of the backfield. Getting the full point PPR on DraftKings is huge for a running back, and will have plenty of chances to break the 100 yard bonus in either rushing or receiving. He is $400 cheaper than he was in the two previous weeks, and is at home against the Saints who have the 28th DVOA against the rush. The Saints defense has improved a good amount since the beginning of the season, but it was mainly their secondary. They are still weak vs the run, and with this game set to be cold with a bit of weather, the Bills should be running the ball plenty.

Carlos Hyde - SF vs NYG (DK $6,300)

Hyde is looking to be one of the stone locks this week, for multiple reasons, so let's dive in. First off, he is at home against the Giants, who have have the 28th DVOA overall, and the 26th DVOA against the rush. We all know how bad the Giants are, and they simply cannot stop really anyone on defense. They are bad against the run, bad against the pass, and most importantly, bad against running backs in the passing game. Hyde has six or more targets in four straight weeks, including nine or more in the last two. A running back getting that volume is huge, just as I mentioned with McCoy. Hyde has also seen 12 or more rushing attempts in four straight weeks. They are feeding him the ball in all aspects of the game, and with how bad the 49ers quarterback situation is, he should be in for a very busy day.

 

DraftKings Wide Receivers - Week 10 DFS Picks

Cooper Kupp - LAR vs HOU (DK $4,600)

Kupp was a bit unlucky last week with the Rams putting up so many points, yet barley seeing the ball at all. He ended with three catches on five targets for 54 yards and no touchdowns. Yes, Jared Goff, only completed 14 passes, so Kupp didn't have a ton of chances. But this week Kupp has a good match up against the Texans, who have the 16th DVOA against the pass, and the 30th DVOA against WR2. With the inconsistency Sammy Watkins has been showing, Kupp is seeing the second most targets on the team, with 47 targets in the first nine weeks. The Texans defense really isn't as good as people think, and attacking them in this spot is a good call.

A.J. Green - CIN @ TEN (DK $7,700)

Green is simply too cheap this week. A player with his skill, and his potential ceiling of points should not be under $8K. Whenever a player is in a spot like this, you want to jump all over him, since he price won't stay this low. Yes, his ownership could get a bit out of hand in GPPs, but having legit two touchdown upside for under $8K is fantastic. Last week he was ejected from the game for a fight, so his stats are a bit out of wack. Without last game, he has 46 targets in the prior five, and four touchdowns over that span. Pretty straight forward spot, don't over think it because of last week.

 

DraftKings Tight End - Week 10 DFS Pick

Kyle Rudolph - MIN @ WAS (DK $4,600)

Rudolph is one of the more consistent tight ends in the league, and is viable for any format this week. He has seven or more targets in four straight weeks, and has two touchdowns over that span. He has become one of the favorite targets for backup quarterback Case Keenum, and gets the volume any DFS player loves. Rudolph also has a very favorable match up, since he is up against the Redskins, who have the 29th DVOA against tight ends. Really like him in this spot, just getting up to his price may be hard, if you are trying to roster two top end running backs.

 

DraftKings Defense - Week 10 DFS Pick

Chicago Bears vs Green Bay Packers (DK $3,000)

Bears are going to be one of the more popular options at defense this week, and it comes with good reason. They are up against at Brett Hundley led Packers team, who as we all saw on Monday night, are very bad. The Packers are having a ton of trouble moving the ball offensively, and picking on them in fantasy is a good call. The Bears have 14 sacks over the past four weeks, along with four interceptions. They are putting pressure on the quarterback, and forcing bad decisions. They aren't too expensive, and should have a good floor of points.

 

More Week 10 DFS Analysis

 

NFL DFS Premium Tools & Research

Get a free trial of our powerful NFL Premium Tools. Our famous Matchup Rating Projections, DFS Cheat Sheets, and NFL Lineup Optimizer/Generator.

Win more. Try the most advanced lineup optimizer in daily fantasy football.

Sign Up Now!




REAL-TIME FANTASY NEWS

Noah Schultz

White Sox to Promote Top Pitching Prospect Noah Schultz
Tyler Soderstrom

Slugs Two Home Runs in Win Over Mets
Adley Rutschman

Placed on 10-Day Injured List With Ankle Inflammation
George Springer

Suffers Fractured Toe on Saturday
Gabriel Moreno

Likely Headed to Injured List
Kevin Lankinen

Will Play Saturday Night
Blake Coleman

Available Against Kraken
Niklas Kokko

Makes First Career Start Saturday
Anthony Stolarz

Unavailable for Final Three Games
Roope Hintz

Not Expected to Return During Regular Season
Jacob Markstrom

Done for the Season
Markquese Bell

Facing Felony, Misdemeanor Drug Charges
Juan Soto

Could Return for Next Homestand
Corbin Carroll

Officially Back in Saturday's Lineup
Max Muncy

Hits Three Homers, Including Walk-Off Blast
Adonai Mitchell

Can Adonai Mitchell Become the Jets' WR2?
Saquon Barkley

Is Saquon Barkley Still a Safe Bet to Perform Despite His Falling Dynasty Ranking?
Michael Wilson

Varied Opinions on Michael Wilson Could Create Unique Trade Opportunities
Jake Ferguson

Accurately Priced as a Low-End TE1
Tyreek Hill

Faces Uncertain Future
Brock Bowers

Still a Top-15 Player in Dynasty Leagues Despite Injury-Plagued Season
Gavin Sheets

Goes Yard Twice, Including Walk-Off Round-Tripper
Washington Commanders

Commanders Host Omar Cooper Jr. for a Pre-Draft Visit
NFL

Makai Lemon to be a Top-20 Draft Pick This Year?
Corbin Carroll

Expected to Start on Saturday
Wyatt Langford

Forced From Friday's Game With Quad Tightness
Bijan Robinson

Falcons Pick Up Bijan Robinson's Fifth-Year Option
Kris Bubic

Dominates White Sox With 11 Strikeouts on Friday
Royce Lewis

Headed for Injured List
Mack Hollins

Can Mack Hollins Maintain a Starting Role in New England in 2026?
Clay Holmes

Removed With Hamstring Tightness
Malik Washington

Has Breakout Potential After Offseason Movement in Miami
Mike Gesicki

Is Mike Gesicki a Buy-Low Candidate After Down 2025?
Cristian Javier

Placed on 15-Day Injured List
Jayden Reed

Poised for Larger Role in Green Bay Following Offseason Movement
Matthew Golden

Does Matthew Golden Have a Clear Path to a Starting Role in His Sophomore Season?
Jaylon Tyson

Rejoins Cavaliers Lineup as Starter
Klay Thompson

Misses Friday's Game Due to Illness
Kevin Huerter

Back in Action Friday
Sam Hauser

Cleared to Play Friday
Neemias Queta

Ready to Take on Pelicans
Derrick White

Good to Go Friday
Jaylen Brown

Active on Friday
Josh Giddey

Still Out Friday
Miles McBride

Exits Knicks Lineup Friday
Mitchell Robinson

Sidelined on Friday
Norman Powell

Won't Play Against Wizards
Tyler Herro

Out on Friday
Saddiq Bey

Herbert Jones Resting Friday
Immanuel Quickley

Unavailable Friday
Julius Randle

Misses Second Straight Game
Jayson Tatum

Won't Play Friday
Jackson Chourio

Still Not Cleared to Hit
Dontayvion Wicks

Eagles Acquiring Dontayvion Wicks From the Packers
Brent Rooker

A's Place Brent Rooker on 10-Day Injured List With Oblique Strain
J.T. Realmuto

Back in Friday's Lineup
Parker Meadows

Goes on 10-Day Injured List With Broken Arm, Concussion
Seiya Suzuki

Back From the Injured List
Carlos Ulberg

A Slight Underdog
Jiří Procházka

Jiri Prochazka Can Become UFC Champion Again
Paulo Costa

Makes his Light-Heavyweight Debut
Azamat Murzakanov

Looks To Remain Unbeaten
Josh Hokit

Looks To Remain Undefeated
Curtis Blaydes

A Favorite At UFC 327
DJ Giddens

an Easily Replaceable Insurance Back
Kenny Moore II

and Colts Seeking a Trade
Hunter Henry

Could Be Impacted by NFL Draft
AJ Barner

a Mispriced Dynasty Asset
Cedric Tillman

Nearing Cut Candidacy in Dynasty Leagues
Sam Carrick

to Miss Start of Playoffs
Alex Lyon

Questionable for Start of Postseason
Dakota Joshua

Unlikely to Return This Season
John Gibson

Exits Thursday's Game Due to Neck Problem
Miro Heiskanen

Uncertain for Playoffs
Brandon Hagel

Expected to Return Before End of Regular Season
Roman Josi

Nursing Upper-Body Injury
Trey Murphy III

Unavailable Against Celtics
Dejounte Murray

Remains Out Friday
Zion Williamson

Won't Suit Up Friday
Jalen Williams

Out on Friday
Jarrett Allen

Won't Play Against Hawks
Moritz Seider

has Five-Point Game on Thursday
Cole Caufield

Reaches 50 Goals
Blake Coleman

Unavailable Thursday
Quinton Byfield

Cleared to Play Thursday
Thomas Chabot

Makes Surprise Return Thursday
Luke Hughes

to Miss Rest of Season
Stuart Skinner

Faces Devils Thursday
Nazem Kadri

to "Miss Some Games" With Finger Injury
Corbin Carroll

Dealing With Hip Injury, Not Expected to Miss Much Time
Tyrrell Hatton

a Steady Option at The Masters
Justin Thomas

a High-Risk, High-Reward Option at The Masters
PGA

Sungjae Im a Volatile Option at the Masters
Nicolai Hojgaard

Carrying Momentum Into The Masters
Si Woo Kim

in Strong Form Heading to The Masters
Chris Gotterup

Ready to Make His Masters Debut
Patrick Reed

Brings Momentum to The Masters
Jon Rahm

Looks Poised for His Second Green Jacket
Adam Scott

Form Points to Him Competing at Masters
Jordan Spieth

Finding Consistency Heading to Masters
Hideki Matsuyama

Trending In Right Direction For Masters
Tommy Fleetwood

a Contender if his Putter Cooperates at The Masters
Collin Morikawa

Vegas has Lost Confidence in Collin Morikawa Ahead of Masters Tournament
Ludvig Aberg

One of the Top Plays For This Week's Masters Tournament
Rory McIlroy

Set to Defend his Long-Awaited Masters Victory
Bryson DeChambeau

Looks to Finally Claim a Green Jacket
Patrick Cantlay

Needs Plenty to Go Right at Augusta
Harris English

Playing Solid Golf Heading to Masters
Sam Burns

Bouncing Back Nicely After Slow Start to 2026 Season
Corey Conners

Quietly Putting Together A Strong 2026 Season
Russell Henley

Looks to Bounce Back At Masters
Chris Duncan

Suffers Second-Round Submission Loss
Renato Moicano

Gets Back In The Win Column
Tabatha Ricci

Gets Outgrappled
Virna Jandiroba

Bounces Back
Brendson Ribeiro

Suffers First-Round Submission Loss
Abdul-Rakhman Yakhyaev

Earns First-Round Submission Win
Rafael Estevam

Suffers His First Loss
Ethyn Ewing

Dominates At UFC Vegas 115
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF