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DraftKings, FanDuel Daily Fantasy Basketball Picks (4/22/22): Today's Top NBA DFS Lineups

Giannis Antetokounmpo - NBA DFS Picks, Daily Fantasy Basketball Lineups

The top daily fantasy basketball lineup picks for DraftKings and FanDuel on April 22nd, 2022. Max Kulish provides NBA DFS analysis and sleeper picks for building optimal DFS rosters.

Happy Friday RotoBallers! Welcome to a playoff edition of the Friday night top plays. These articles focus on the overall best plays, which are typically more suited for cash games. However, with rotations getting shortened and the slate being so small, there probably isn't going to be a ton of leverage to be found, so consider these suggestions GPP viable as well (some exceptions may apply).

This article will provide you with my daily fantasy basketball lineup picks for DraftKings and FanDuel on 4/22/22. Remember to monitor NBA injury news and our awesome new NBA injuries report tool as the slate can completely change before lineups lock.

As always, feel free to follow my Twitter (@Maxadelphia), to keep up to date with NBA news and for my nightly NBA bets if you're into that sort of thing. Let's go!

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DraftKings and FanDuel Guards - NBA DFS Lineup Picks

Trae Young - PG, ATL vs MIA ($9,400 DK, $9,000 FD)

I'm not here to lie to you fine readers and say that Young has been good through two playoff games. In fact, he was objectively bad in both games in Miami. So why I am putting him in top plays? Potential volume, that's why! Young boasted a top-3 usage rate in the NBA this year, and with the Hawks staring down a potential 0-3 series deficit, I am going to bank on Young getting a TON of usage this evening.

CJ McCollum - PG/SG, NO vs PHX ($8,200 DK, $8,600 FD)

McCollum has been rock steady through two games these playoffs. With fantasy scores of 48 and 50 in those first two games, McCollum hasn't only been scoring, he's been involved on both ends of the court. Even in Game 2, where Brandon Ingram was taking over the game late, McCollum still managed to get up 18 shot attempts, including 10 attempts from 3.

Landry Shamet - SG/SF, PHX @ NO ($3,800 DK, $3,800 FD)

This is our first slate of the playoffs with major players out due to injury, and I would say that Devin Booker's injury is about as impactful as it gets. Shamet has been the defacto Booker replacement throughout the year, including him playing 12 minutes in the second half of Game 2 after Booker went down. Shamet will likely be pretty chalky tonight, but if he does end up in the starting lineup I think he's worth a look.

Others to consider: Chris Paul ($8,900 DK, $10,200), Alex Caruso ($5,100 DK, $5,000 FD)

 

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DraftKings and FanDuel Forwards - NBA DFS Lineup Picks

Giannis Antetokounmpo - SF/PF, MIL @ CHI  ($11,200 DK, $12,000 FD)

Giannis had a monstrous game on Wednesday night, posting 75 fantasy points, which was the biggest fantasy game by anyone so far this post-season. The Bulls have no means of slowing down the Greek Freak, and with Khris Middleton out for at least two weeks, I expect Giannis to take over a fair chunk of Middleton's usage.

Cameron Johnson - SF/PF, PHX @ NO ($4,700 DK, $5,100 FD)

Johnson is an easy book to read: he likes to shoot 3's, and he likes to do so in high quantities. The Suns need to replace Devin Booker's 20+ attempts a game, and why not give some of those attempts to the guy who was an elite shooter all year? Johnson is a measly 2-8 from 3 so far this series, but with all the minutes and attempts that Booker's absence leaves, I think there is a very real chance that this could be a Johnson explosion game.

Wesley Matthews - SG/SF, MIL @ CHI ($4,100 DK, $4,100 FD)

Matthews has started both games for the Bucks in the series, playing 27 minutes in Game 1 and playing 34 minutes in Game 2. That Game 2 number is key since we can see the minutes inflate in correlation with the Middleton injury. Matthews is probably the Bucks' best 3-point shooter with Middleton out, and I expect him to get a bit more opportunity the remainder of the series.

Others to consider: Brandon Ingram ($9,000 DK, $9,100 FD), Herbert Jones ($4,500 DK & FD)

 

DraftKings and FanDuel Centers - NBA DFS Lineup Picks

Deandre Ayton - C, PHX @ NO ($7,600 DK, $7,900 FD)

This slate is all about how you think the Bucks & Suns fill the voids left by their injured All-Stars. Ayton had a great Game 1, and a more quiet Game 2; taking only 6 total shots. Center is pretty weak tonight, but I think Ayton provides the highest ceiling tonight, assuming the Suns try and get him involved.

Bobby Portis - PF/C, MIL @ CHI ($5,700 DK, $5,800 FD)

This brings us to the conclusion of this Suns/Bucks suggestions article. Portis is the Bucks' key bench scorer, and we've seen him have pop-off games in the playoffs last year. Whether he gets bumped up to the starting lineup or not, I expect him to be fired up for tonight after only playing 6 minutes in Game 2 before catching an elbow to the face and being forced to leave.

Others to consider: Jonas Valanciunas ($7,400 DK, $8,000 FD), Heat (if Bam Adebayo sits)



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REAL-TIME FANTASY NEWS

Tyjae Spears

has Limited Long-Term Upside in Dynasty Formats
Jaylen Wright

a Buy-Low Candidate as a Handcuff?
Ollie Gordon II

Dynasty Value Takes a Hit After Teammate's Extension
Ryan Johnson

Takes Over as Canucks GM, Sedins Promoted to Co-Presidents
Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
Micah Parsons

Expected to Miss the Early Part of the Season
Colby Parkinson

a Clear Dynasty Sell-High Candidate Entering 2026
Omarion Hampton

Poised for Year 2 Breakout in Los Angeles
Blake Corum

Dynasty Stock Rising After Encouraging 2025 Campaign
Jaxson Dart

Does Jaxson Dart Carry High-End Dynasty QB1 Upside?
David Montgomery

Dynasty Stock Rising Following Move to Houston
Chris Godwin Jr.

Can Chris Godwin Jr. Re-Establish His Dynasty Value in 2026?
Malik Willis

Not Set Up for Immediate Success in Miami
Terrance Ferguson

has Promising Receiving Skills in Crowded TE Room in L.A.
Brenton Strange

Is Brenton Strange a Top-15 Dynasty Tight End?
T.J. Watt

Steelers Ready to Move on From T.J. Watt?
Jacory Croskey-Merritt

Must Make Gains as Pass-Catcher to Take the Next Step
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Kaytron Allen

Could Kaytron Allen Take on a Big Role Right Away?
Demond Claiborne

Has Long-Term Appeal in Minnesota
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Adam Randall

to Contribute as a Pass-Catcher Right Away?
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Nicholas Singleton

Could Contribute Right Away
Bryce Lance

a Perfect Fit in New Orleans?
Mike Washington Jr.

Can Mike Washington Jr. Force a Backfield Split in Vegas?
Paul Reed

Makes Big Impact Off the Bench Wednesday
Daniss Jenkins

Contributes 19 Points As Starter
Cade Cunningham

Tallies 39 Points in Losing Effort
Max Strus

Notches 20 Points With Six Triples
Evan Mobley

Close to Triple-Double Wednesday
Jarrett Allen

Records Double-Double in Game 5 Win
James Harden

Leads the Way for Cavaliers in Game 5 Victory
Quinn Hughes

Finishes Postseason With 15 Points
Matt Boldy

Posts Two Assists in Season-Ending Loss
Scott Wedgewood

Perfect in Relief Effort
Martin Necas

Records Another Multi-Point Game
Brett Kulak

Sends Avalanche Into Conference Finals
Brayden McNabb

Suspended for One Game
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
Juan Soto

Exits Wednesday's Game Early with Ankle Injury
Kevin Huerter

is Cleared to Return for Game 5
Caris LeVert

is Available for Game 5 on Wednesday
Duncan Robinson

is Out for Game 5
Keegan Murray

Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Sam Malinski

Set to Miss Second Straight Game
Artturi Lehkonen

Unlikely to Play Wednesday
Matthew Schaefer

Wins Calder Trophy
TOR

Maple Leafs Fire Head Coach Craig Berube
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

Comes Alive in Game 5 Against Timberwolves
Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Victor Wembanyama

Leads Spurs to Big Win in Game 5
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Mason McTavish

Delivers Two Assists Tuesday Night
Pavel Dorofeyev

Pots Two Goals in Vital Game 5 Win
Josh Doan

Records Two Assists in Game 4 Victory
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF