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DraftKings, FanDuel Daily Fantasy Basketball Picks (4/22/22): Today's Top NBA DFS Lineups

Giannis Antetokounmpo - NBA DFS Picks, Daily Fantasy Basketball Lineups

The top daily fantasy basketball lineup picks for DraftKings and FanDuel on April 22nd, 2022. Max Kulish provides NBA DFS analysis and sleeper picks for building optimal DFS rosters.

Happy Friday RotoBallers! Welcome to a playoff edition of the Friday night top plays. These articles focus on the overall best plays, which are typically more suited for cash games. However, with rotations getting shortened and the slate being so small, there probably isn't going to be a ton of leverage to be found, so consider these suggestions GPP viable as well (some exceptions may apply).

This article will provide you with my daily fantasy basketball lineup picks for DraftKings and FanDuel on 4/22/22. Remember to monitor NBA injury news and our awesome new NBA injuries report tool as the slate can completely change before lineups lock.

As always, feel free to follow my Twitter (@Maxadelphia), to keep up to date with NBA news and for my nightly NBA bets if you're into that sort of thing. Let's go!

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DraftKings and FanDuel Guards - NBA DFS Lineup Picks

Trae Young - PG, ATL vs MIA ($9,400 DK, $9,000 FD)

I'm not here to lie to you fine readers and say that Young has been good through two playoff games. In fact, he was objectively bad in both games in Miami. So why I am putting him in top plays? Potential volume, that's why! Young boasted a top-3 usage rate in the NBA this year, and with the Hawks staring down a potential 0-3 series deficit, I am going to bank on Young getting a TON of usage this evening.

CJ McCollum - PG/SG, NO vs PHX ($8,200 DK, $8,600 FD)

McCollum has been rock steady through two games these playoffs. With fantasy scores of 48 and 50 in those first two games, McCollum hasn't only been scoring, he's been involved on both ends of the court. Even in Game 2, where Brandon Ingram was taking over the game late, McCollum still managed to get up 18 shot attempts, including 10 attempts from 3.

Landry Shamet - SG/SF, PHX @ NO ($3,800 DK, $3,800 FD)

This is our first slate of the playoffs with major players out due to injury, and I would say that Devin Booker's injury is about as impactful as it gets. Shamet has been the defacto Booker replacement throughout the year, including him playing 12 minutes in the second half of Game 2 after Booker went down. Shamet will likely be pretty chalky tonight, but if he does end up in the starting lineup I think he's worth a look.

Others to consider: Chris Paul ($8,900 DK, $10,200), Alex Caruso ($5,100 DK, $5,000 FD)

 

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DraftKings and FanDuel Forwards - NBA DFS Lineup Picks

Giannis Antetokounmpo - SF/PF, MIL @ CHI  ($11,200 DK, $12,000 FD)

Giannis had a monstrous game on Wednesday night, posting 75 fantasy points, which was the biggest fantasy game by anyone so far this post-season. The Bulls have no means of slowing down the Greek Freak, and with Khris Middleton out for at least two weeks, I expect Giannis to take over a fair chunk of Middleton's usage.

Cameron Johnson - SF/PF, PHX @ NO ($4,700 DK, $5,100 FD)

Johnson is an easy book to read: he likes to shoot 3's, and he likes to do so in high quantities. The Suns need to replace Devin Booker's 20+ attempts a game, and why not give some of those attempts to the guy who was an elite shooter all year? Johnson is a measly 2-8 from 3 so far this series, but with all the minutes and attempts that Booker's absence leaves, I think there is a very real chance that this could be a Johnson explosion game.

Wesley Matthews - SG/SF, MIL @ CHI ($4,100 DK, $4,100 FD)

Matthews has started both games for the Bucks in the series, playing 27 minutes in Game 1 and playing 34 minutes in Game 2. That Game 2 number is key since we can see the minutes inflate in correlation with the Middleton injury. Matthews is probably the Bucks' best 3-point shooter with Middleton out, and I expect him to get a bit more opportunity the remainder of the series.

Others to consider: Brandon Ingram ($9,000 DK, $9,100 FD), Herbert Jones ($4,500 DK & FD)

 

DraftKings and FanDuel Centers - NBA DFS Lineup Picks

Deandre Ayton - C, PHX @ NO ($7,600 DK, $7,900 FD)

This slate is all about how you think the Bucks & Suns fill the voids left by their injured All-Stars. Ayton had a great Game 1, and a more quiet Game 2; taking only 6 total shots. Center is pretty weak tonight, but I think Ayton provides the highest ceiling tonight, assuming the Suns try and get him involved.

Bobby Portis - PF/C, MIL @ CHI ($5,700 DK, $5,800 FD)

This brings us to the conclusion of this Suns/Bucks suggestions article. Portis is the Bucks' key bench scorer, and we've seen him have pop-off games in the playoffs last year. Whether he gets bumped up to the starting lineup or not, I expect him to be fired up for tonight after only playing 6 minutes in Game 2 before catching an elbow to the face and being forced to leave.

Others to consider: Jonas Valanciunas ($7,400 DK, $8,000 FD), Heat (if Bam Adebayo sits)



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REAL-TIME FANTASY NEWS

Giannis Antetokounmpo

Magic Reportedly Have Giannis Antetokounmpo on Their Radar
Ajay Mitchell

Won't Play Sunday
Dylan Harper

Not on Injury Report for Game 4
De'Aaron Fox

Off the Injury Report Ahead of Game 4
Jalen Williams

Questionable for Sunday Night
Ja'Tavion Sanders

a Dynasty Dart Throw With Potential Untapped Upside
Geno Smith

a Low-Cost Dynasty Add Who Still Comes with Risk
C.J. Stroud

Still a Capable and Undervalued Dynasty QB2
Bhayshul Tuten

More Big Plays in 2026 Could Transform Bhayshul Tuten into a Dynasty Steal
Joe Mixon

Is Joe Mixon's NFL Career Over?
MLB

Orioles-Tigers Game Postponed on Saturday
RJ Harvey

to be Relegated to Third-Down Role After Rookie RB Addition?
Baker Mayfield

A Lot of Uncertainty Surrounding Baker Mayfield Going into Fourth Year in Tampa
Brian Robinson Jr.

a Must-Have Handcuff in Dynasty Leagues?
Sam LaPorta

Could be Excellent Buy-Low Candidate for Risk-Tolerant Managers
Jordyn Tyson

on a "Maintenance Plan" During Offseason Workouts
Kenneth Walker III

One of Dynasty's Biggest Risers for 2026
D'Andre Swift

an Underappreciated Dynasty Buy Candidate
Ray Davis

Still a Dynasty Stash Despite a Lack of Standalone Value
Travis Kelce

Now a Low-Cost Dynasty Rental
DJ Moore

a Reasonable Buy Candidate Now That Dynasty Market Has Cooled
MLB

Rays-Yankees Postponed on Saturday
Devin Vassell

Posts 20 Points in Game 3 Loss
De'Aaron Fox

Struggles From Deep in Friday's Loss
Victor Wembanyama

Held to Four Rebounds in Game 3 Loss
Jaylin Williams

Catches Fire From Deep Friday
Jared McCain

Drops Playoff-High 24 Points in Game 3
Nazem Kadri

Contributes an Assist in Losing Effort
Shai Gilgeous-Alexander

Guides Thunder to 2-1 Series Lead
Ajay Mitchell

Does Not Return in Game 3 Win
Ross Colton

Nets Lone Avalanche Goal Friday Night
Rasmus Andersson

Extends Assist Streak to Four Games
Pavel Dorofeyev

Focuses on Playmaking in Friday's Win
Jack Eichel

Enjoys Multi-Point Outing in Game 2 Win Friday
Ivan Barbashev

Amasses Three Points as Golden Knights Grab 2-0 Series Lead
Jordan James

Most Likely to be 49ers' RB2 in 2026
Mickey Moniak

Heads to Injured List With Ankle Sprain
Rudy Gobert

Earns Eighth All-Defensive First-Team Selection
Victor Wembanyama

Headlines 2025-26 All-Defensive First Team
Ajay Mitchell

Starting Game 3 Against Spurs
Dylan Harper

Available for Game 3 Against Thunder
De'Aaron Fox

Returns to Action Friday
Jalen Williams

Won't Play Friday Night
Derrick Henry

Remains in RB1 Discussion
Ladd McConkey

is Solid Buy-Low Candidate
Ryan Flournoy

an Intriguing Dynasty Stash Option
Jalen Nailor

is Expected to Have Larger Role in Las Vegas
Frederik Andersen

Hurricanes Keep Faith in Frederik Andersen
Devon Levi

Attracting Interest From Senators
Jacoby Brissett

Cardinals Not Close to a Reworked Deal
Scott Wedgewood

Starting Game 2 Against Golden Knights
Ben Hutton

Scratched for Game 2 Against Avalanche
Mark Stone

Won't Play Friday
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
Cale Makar

Remains Out Friday
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Evan Mobley

Fills the Box Score in Game 2 Loss
James Harden

Held to Two Assists Thursday
Donovan Mitchell

Leads Cavaliers in Scoring in Game 2 Defeat
Sebastian Aho

Picks Up an Assist in Series-Opening Loss
Seth Jarvis

Needs 33 Seconds to Score in Game 1 Loss
Jaccob Slavin

Struggles in Game 1 Against Canadiens
Jakub Dobes

Sharp in Game 1 Victory
Cole Caufield

Bags Two Points in Impressive Road Win
Juraj Slafkovsky

Opens Conference Finals With Three-Point Performance
Nick Suzuki

Notches Three Assists in Game 1 Win Over Hurricanes
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Alex Tuch

Hopes to Remain in Buffalo
Sidney Crosby

Wants to Play for "as Many Years as Possible"
Robby Snelling

Will Undergo Tommy John Surgery
Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
CFB

Lincoln Riley Believes USC is Ready for Playoff Run
CFB

Notre Dame-Stanford Rivalry Renewed Through 2028
CFB

Ahmad Hardy Says He's "Back to the Road to Success"
CFB

Texas Tech Graduate Judge Recuses Himself from Brendan Sorsby Case
CFB

UCLA Tackle Jordan Davis Officially Eligible for 2026 Season
CFB

Bret Bielema Supports Significant College Football Playoff Expansion
Michael Thorbjornsen

Brings High Upside to CJ Cup Byron Nelson
Luke List

Carrying Poor Form Into CJ Cup Byron Nelson
Tom Kim

Hoping to Build on Strong Myrtle Beach Finish
PGA

Sungjae Im Brings Upside to TPC Craig Ranch
Billy Horschel

Looking for Turnaround at CJ Cup Byron Nelson
Adam Hadwin

Difficult to Trust at TPC Craig Ranch
Tony Finau

Looking for Consistency at TPC Craig Ranch
Luke Clanton

Searching for Form at CJ Cup Byron Nelson
Aaron Rai

Withdraws From CJ Cup Byron Nelson
Wyndham Clark

Can Wyndham Clark Find Form at CJ Cup?
Si Woo Kim

Looks To Stay Hot at CJ Cup
Scottie Scheffler

to Defend CJ Cup Byron Nelson Title This Week
Jordan Spieth

Looking For Victory at TPC Craig Ranch
PGA

Matti Schmid Looks to Keep Recent Momentum Going at TPC Craig Ranch
Brooks Koepka

a High-Upside Play at CJ Cup Byron Nelson
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Gerrit Cole

to Make Season Debut on Friday Against Rays
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
CFB

Kemario Taylor a Breakout Candidate at Quarterback
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Corey Seager

Going on Injured List With Back Injury
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
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SP
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