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DraftKings Daily Fantasy Football Picks (Week 15): NFL DFS Lineups

The top daily fantasy football lineup picks for DraftKings in Week 15. Ben Rolfe's NFL DFS analysis and sleepers for building optimal DFS rosters.

Two Saturday games on top of the usual prime time games has really left this slate a little devoid of options. However, more significantly is the loss of the Chiefs, Rams, Chargers and Saints to prime time slots on Thursday, Sunday and Monday. That has left us looking more for defenses to pick against this week than looking at explosive offenses. Some prime examples are the Falcons and Bengals who have struggled to stop teams at all this year and have looked pretty ugly on defense. Below are my DraftKings DFS Lineup Picks for Week 15.

These DraftKings lineup recommendations are based on matchups, performances so far, overall upside/talent levels, opportunity, and other factors such as Vegas odds, home field advantage, and more. There are quite a few great value plays available, so read on to find out which players are the best for Week 15.

Good luck with your DraftKings DFS lineups!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 15 Picks

Tom Brady - NE @ PIT (DK $5,900)

When you look on DraftKings this looks a bad matchup for Brady. The Steelers appear on there as the ninth-toughest matchup for quarterbacks. However, the Steelers home/road splits have been weird this season. At home, the Steelers defense is actually surrendering five more fantasy points to quarterbacks at home (21.1) than on the road (16.1). In addition, it is expected this game will be high scoring with the over/under having moved from its opening line of 49.5 up to 52. In addition, Brady looked great last week and appears to be preparing to peak at the right time.

Derek Carr - OAK @ CIN (DK $5,400)

I am not sure trusting Carr is ever something I want to do but this is a nice spot for him. The Bengals defense has had major issues this season, surrendering 20 fantasy points per game to opposing quarterbacks on the road. They are also coming off a kitchen sink game on the road against the Chargers and against the lowly Raiders could be primed for a let-down. Carr has scored over 22.5 fantasy points each of the last two weeks.

 

DraftKings DFS Running Backs - Week 15 Picks

David Johnson - ARI @ ATL (DK $7,100)

Facing the Falcons feels almost a gimme pick for the opposing running back right now. The Falcons are currently surrendering 25.1 fantasy points to opposing #1 running backs at home. Any fears that with the Cardinals focusing on the future might lead to fewer touches for Johnson should have been assuaged last week when he had 15 carries and 10 targets in the passing game.

Dalvin Cook - MIN vs. MIA (DK $6,500)

I am gambling that we see a shift in attitude in Minnesota this week with a new head coach. Cook is incredibly talented but has been misused this season. The Vikings offensive line is not great but the Dolphins are surrendering an average of 20 fantasy points per game to opposing #1 running backs when they play on the road. Cook has scored double-digit fantasy points in each of his last three goals and appears to have had a very defined role in the passing game in recent weeks.

Gus Edwards - BAL vs. TB (DK $4,400)

I am not ready to give up on Edwards in Baltimore. Kenneth Dixon had the better week against the Chiefs but Edwards is still the number one back. In addition, he is facing a leaky Buccaneers defense who have allowed an average of 25.6 fantasy points to opposing #1 running backs on the road. That defense has been allowing an average of 35 fantasy points to running backs in general on the road. Therefore, even if Edwards does not see the bulk of the carries there should still be value for him in this game.

 

DraftKings DFS Wide Receivers - Week 15 Picks

Julio Jones - ATL vs. ARI (DK $8,400)

In a year of chaos for the Falcons Jones stands tall. Jones found the end zone twice last week as he bounced back from a tough week against the Ravens. He is seeing an average of just under eight targets per game and has scored touchdowns in four of his last six games. His matchup this week is actually pretty favorable with the Cardinals allowing 23 fantasy points per game to opposing #1 wide receivers at home. He has missed practice twice this week but one was precautionary and the other was for flu-like symptoms which are not expected to keep him out this weekend.

Corey Davis - TEN @ NYG (DK $5,600)

Davis has been extremely hit-or-miss this season and the Giants defense has generally been quite good at home against opposing wide receivers. However, they have surrendered an average of 16.1 fantasy points per game to the opposing number one receiver in MetLife stadium. With the Titans in the AFC playoff hunt and severely short-handed when it comes to weapons I expect Davis to see plenty of targets this weekend.

Larry Fitzgerald - ARI @ ATL (DK $4,700)

Fitzgerald and Johnson are the main weapons the Cardinals have and this week both have great matchups. Fitzgerald generally lines up out of the slot and the Falcons have allowed 13.1 fantasy points per game against the slot receiver at home. Jones saw nine targets next week and I think there is a very real chance it sets a season-high in a game which could have more scoring than many expect.

 

DraftKings DFS Tight Ends - Week 15 Picks

Jared Cook - OAK @ CIN (DK $5,600)

This feels like a slam dunk for me if I have cash to spare at the position. Cook has had over 20 fantasy points each of the last two weeks and has a matchup against the 26th worst defense against the tight end. He is the only reliable weapon the Raiders have and I expect them to use him plenty this week.

Vance McDonald - PIT vs. NE (DK $3,900)

With Zach Ertz and Travis Kelce missing from the slate this is a thin week at the tight end position. McDonald seems to have a fairly good floor and there is potential for upside against a slow New England Patriot defense, who are allowing over 10 fantasy points per game to opposing #1 tight ends. I would prefer Cook but if you are tight for money this is a solid pick.

 

DraftKings DFS Defenses - Week 15 Picks

Buffalo Bills vs. Detroit Lions (DK 2,800)

A Lions offense that has not looked very good now has to travel on the road to a stadium that seems to experience all sorts of weather conditions. Add in that the Bills defense has been solid this year and this actually becomes quite an easy pick for me this week.

More Weekly DFS Analysis




REAL-TIME FANTASY NEWS

Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Larry Nance Jr.

is Questionable for Game 1 on Tuesday
OG Anunoby

is Probable for Tuesday's Game 1
Luke Kornet

is Cleared for Game 1
New Orleans Pelicans

Jamahl Mosley Agrees to Become Pelicans Next Head Coach
De'Aaron Fox

is Ruled Out for Game 1 on Monday
Ukko-Pekka Luukkonen

Set to Start Game 7
Corey Seager

Going on Injured List With Back Injury
Tage Thompson

Can Match Franchise Record With Another Multi-Point Game
Nick Suzuki

Seeks More Road Success Monday
Lane Hutson

Riding a Five-Game Assist Streak Into Game 7
Filip Gustavsson

Needs Offseason Surgery
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Cam Skattebo

Dynasty Stock Rising Following NFL Draft
Kaleb Johnson

Logging First-Team Reps in OTAs
Evan Engram

Dynasty Value Fading After Production Decline in 2025
TreVeyon Henderson

Dynasty Outlook Clouded By Split Backfield in New England
Caleb Williams

' Dynasty Upside Remains Sky-High Entering 2026
Bijan Robinson

Is Bijan Robinson the No. 1 Overall Player in Dynasty Formats?
Woody Marks

Should Have Plenty of Opportunities to Catch Passes
Drew Allar

Working as QB4 in First OTA Session
Aaron Rodgers

Reports to Steelers Facilities on Monday
Alvin Kamara

Saints Remain Non-Committal on Alvin Kamara's Future
Chris Olave

Saints Continue to Work on Extension With Chris Olave
Parker Washington

a Sneaky Trade Target in Dynasty Leagues?
Melquizael Costa

Drops Decision At UFC Vegas 117
Jarquez Hunter

Can Jarquez Hunter's Dynasty Outlook Improve in Year 2?
Arnold Allen

Bounces Back
James Conner

Off the Dynasty Radar Entirely?
Elijah Arroyo

Will Elijah Arroyo Continue to Have Trouble Getting on the Field?
Daniel Santos

Suffers Second-Round TKO Loss
Tre Tucker

Not a Long-Term Solution in Dynasty Leagues
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jack Bech

a Dynasty Hold as New-Look Raiders Offense Takes Shape
Jaydon Blue

a Low-Value Dynasty Stash Until Depth Charts are Settled
Makai Lemon

a Top-Five Pick in Dynasty Rookie Drafts
George Kittle

a Dynasty Buy with League-Winning Potential
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Chris Rodriguez Jr.

a Dynasty Sleeper with High Touchdown Potential
Tobias Harris

Goes Cold in Game 7 Loss
Quinn Hughes

Open to Signing Extension This Offseason
Jalen Duren

Finishes Game 7 with Quiet Line
Cade Cunningham

Endures Cold Shooting Night Sunday
Joel Eriksson Ek

Misses Second Round Due to Heel Injury
Sam Merrill

Catches Fire in Game 7 Win
Evan Mobley

Posts Versatile Double-Double in Game 7
Jonas Brodin

Sits Out Round 2 Due to Toe Injury
Donovan Mitchell

Guides Cavaliers Into East Finals
Sam Malinski

Practices Fully Sunday
Jarrett Allen

Scores 23 Points in Cavs' Game 7 Rout of Pistons
Josh Manson

Rejoins Practice
Kevin Huerter

Active on Sunday Night
Caris LeVert

Duncan Robinson, Caris LeVert Available Sunday
Dean Wade

Max Strus Replaces Dean Wade in Starting Lineup Sunday
Luke Kornet

Iffy for Monday
Larry Nance Jr.

Won't Play Sunday
De'Aaron Fox

Listed as Questionable for Monday's Action
Jalen Williams

Officially Available for Game 1 Against Spurs
Shai Gilgeous-Alexander

Named MVP for Second Straight Year
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Bones Hyland

Wants to Stay in Minnesota
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Alex Lyon

Likely to Start Game 6 Against Canadiens
Owen Power

Available Saturday
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Max Fried

Heading to Injured List With Elbow Bone Bruise
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Jordan Westburg

to Have Season-Ending Elbow Surgery
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF