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DraftKings Daily Fantasy Football Picks (Week 15): NFL DFS Lineups

The top daily fantasy football lineup picks for DraftKings in Week 15. Ben Rolfe's NFL DFS analysis and sleepers for building optimal DFS rosters.

Two Saturday games on top of the usual prime time games has really left this slate a little devoid of options. However, more significantly is the loss of the Chiefs, Rams, Chargers and Saints to prime time slots on Thursday, Sunday and Monday. That has left us looking more for defenses to pick against this week than looking at explosive offenses. Some prime examples are the Falcons and Bengals who have struggled to stop teams at all this year and have looked pretty ugly on defense. Below are my DraftKings DFS Lineup Picks for Week 15.

These DraftKings lineup recommendations are based on matchups, performances so far, overall upside/talent levels, opportunity, and other factors such as Vegas odds, home field advantage, and more. There are quite a few great value plays available, so read on to find out which players are the best for Week 15.

Good luck with your DraftKings DFS lineups!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 15 Picks

Tom Brady - NE @ PIT (DK $5,900)

When you look on DraftKings this looks a bad matchup for Brady. The Steelers appear on there as the ninth-toughest matchup for quarterbacks. However, the Steelers home/road splits have been weird this season. At home, the Steelers defense is actually surrendering five more fantasy points to quarterbacks at home (21.1) than on the road (16.1). In addition, it is expected this game will be high scoring with the over/under having moved from its opening line of 49.5 up to 52. In addition, Brady looked great last week and appears to be preparing to peak at the right time.

Derek Carr - OAK @ CIN (DK $5,400)

I am not sure trusting Carr is ever something I want to do but this is a nice spot for him. The Bengals defense has had major issues this season, surrendering 20 fantasy points per game to opposing quarterbacks on the road. They are also coming off a kitchen sink game on the road against the Chargers and against the lowly Raiders could be primed for a let-down. Carr has scored over 22.5 fantasy points each of the last two weeks.

 

DraftKings DFS Running Backs - Week 15 Picks

David Johnson - ARI @ ATL (DK $7,100)

Facing the Falcons feels almost a gimme pick for the opposing running back right now. The Falcons are currently surrendering 25.1 fantasy points to opposing #1 running backs at home. Any fears that with the Cardinals focusing on the future might lead to fewer touches for Johnson should have been assuaged last week when he had 15 carries and 10 targets in the passing game.

Dalvin Cook - MIN vs. MIA (DK $6,500)

I am gambling that we see a shift in attitude in Minnesota this week with a new head coach. Cook is incredibly talented but has been misused this season. The Vikings offensive line is not great but the Dolphins are surrendering an average of 20 fantasy points per game to opposing #1 running backs when they play on the road. Cook has scored double-digit fantasy points in each of his last three goals and appears to have had a very defined role in the passing game in recent weeks.

Gus Edwards - BAL vs. TB (DK $4,400)

I am not ready to give up on Edwards in Baltimore. Kenneth Dixon had the better week against the Chiefs but Edwards is still the number one back. In addition, he is facing a leaky Buccaneers defense who have allowed an average of 25.6 fantasy points to opposing #1 running backs on the road. That defense has been allowing an average of 35 fantasy points to running backs in general on the road. Therefore, even if Edwards does not see the bulk of the carries there should still be value for him in this game.

 

DraftKings DFS Wide Receivers - Week 15 Picks

Julio Jones - ATL vs. ARI (DK $8,400)

In a year of chaos for the Falcons Jones stands tall. Jones found the end zone twice last week as he bounced back from a tough week against the Ravens. He is seeing an average of just under eight targets per game and has scored touchdowns in four of his last six games. His matchup this week is actually pretty favorable with the Cardinals allowing 23 fantasy points per game to opposing #1 wide receivers at home. He has missed practice twice this week but one was precautionary and the other was for flu-like symptoms which are not expected to keep him out this weekend.

Corey Davis - TEN @ NYG (DK $5,600)

Davis has been extremely hit-or-miss this season and the Giants defense has generally been quite good at home against opposing wide receivers. However, they have surrendered an average of 16.1 fantasy points per game to the opposing number one receiver in MetLife stadium. With the Titans in the AFC playoff hunt and severely short-handed when it comes to weapons I expect Davis to see plenty of targets this weekend.

Larry Fitzgerald - ARI @ ATL (DK $4,700)

Fitzgerald and Johnson are the main weapons the Cardinals have and this week both have great matchups. Fitzgerald generally lines up out of the slot and the Falcons have allowed 13.1 fantasy points per game against the slot receiver at home. Jones saw nine targets next week and I think there is a very real chance it sets a season-high in a game which could have more scoring than many expect.

 

DraftKings DFS Tight Ends - Week 15 Picks

Jared Cook - OAK @ CIN (DK $5,600)

This feels like a slam dunk for me if I have cash to spare at the position. Cook has had over 20 fantasy points each of the last two weeks and has a matchup against the 26th worst defense against the tight end. He is the only reliable weapon the Raiders have and I expect them to use him plenty this week.

Vance McDonald - PIT vs. NE (DK $3,900)

With Zach Ertz and Travis Kelce missing from the slate this is a thin week at the tight end position. McDonald seems to have a fairly good floor and there is potential for upside against a slow New England Patriot defense, who are allowing over 10 fantasy points per game to opposing #1 tight ends. I would prefer Cook but if you are tight for money this is a solid pick.

 

DraftKings DFS Defenses - Week 15 Picks

Buffalo Bills vs. Detroit Lions (DK 2,800)

A Lions offense that has not looked very good now has to travel on the road to a stadium that seems to experience all sorts of weather conditions. Add in that the Bills defense has been solid this year and this actually becomes quite an easy pick for me this week.

More Weekly DFS Analysis




REAL-TIME FANTASY NEWS

Rashee Rice

Chiefs Have No Plans to Sign Rashee Rice to Long-Term Extension
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Cole Payton

Dynasty Managers Will Have to be Patient with Cole Payton
Taylen Green

Does Taylen Green's Speed Get Him on the Dynasty Radar?
Jack Endries

Is Jack Endries the Tight End of the Future in Cincinnati?
CJ Daniels

a Developmental Stash in Dynasty Leagues
Garrett Nussmeier

a Low-Risk Target with Upside in Dynasty Leagues?
Jam Miller

Has Sneaky Value if He Can Earn a Roster Spot
Justice Hill

a Dynasty Drop Candidate Wherever He's Still Rostered
J'Mari Taylor

Is J'Mari Taylor Worth a Taxi-Squad Spot in Deep Dynasty Leagues?
Greg Dulcich

Has a Lack of Competition Made Greg Dulcich a Dynasty Sleeper?
Carson Beck

a Worthy Investment in the Later Rounds of Rookie Drafts
Devon Toews

Logs Two Assists In Game 3 Defeat
Brett Howden

Nets 10th Postseason Goal
Mitchell Marner

Delivers Two Assists in Comeback Victory
Mark Stone

Returns With Multi-Point Effort
Valeri Nichushkin

Exits Early Sunday
Nathan MacKinnon

Hurt in Game 3 Loss
Isaiah Hartenstein

Provides Steady Production in Defeat
Chet Holmgren

Has a Quiet Offensive Night on Sunday
Shai Gilgeous-Alexander

Held Under 20 Points in Game 4
Stephon Castle

Hands Out Six Assists in Game 4 Win
Devin Vassell

Tallies 13 Points in Game 4 Win
De'Aaron Fox

Records Double-Double as Spurs Even Series
Victor Wembanyama

Sets Tone Early as Spurs Force a Pivotal Game 5
Isaac Guerendo

Could be a Drop Candidate in Dynasty Leagues in 2026
Jayden Higgins

' Dynasty Arrow is Pointing Up With Clear Path to WR2 Role in Houston
Jakobi Meyers

a Sell-High Candidate in Dynasty Formats?
Drake Maye

to Make a Big Leap in 2026 in Second Season With Josh McDaniels?
Jamal Murray

Earns First Career All-NBA Selection
Kevin Durant

Becomes First Player to Make All-NBA Team With Five Franchises
Shai Gilgeous-Alexander

Victor Wembanyama Lead All-NBA First Team
Taylor Hall

Enjoying Life in Carolina
Mark Stone

Returns to Action Sunday
Cale Makar

Rejoins Avalanche Lineup Sunday
Cason Wallace

Joins Starting Unit Sunday
De'Aaron Fox

Doesn't "Feel Great" Entering Game 4
Jalen Williams

Won't Play Sunday
Christian Watson

Is Christian Watson on the Verge of a Legitimate Breakout?
Khalil Shakir

Dynasty Value in Decline
Travis Hunter

Still a Risky Buy, Even at his Sunken Dynasty Cost
Gunnar Helm

a Dynasty Sleeper with Room to Grow
Drake Maye

Is Drake Maye Becoming the Most Valuable Player in Superflex Dynasty Leagues?
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Pat Freiermuth

Steelers Restructure Pat Freiermuth's Contract
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
Evan Mobley

Tallies Series-High 24 Points on Saturday
Donovan Mitchell

Struggles at the Line Saturday
Karl-Anthony Towns

Continues Playmaking Surge on Saturday
OG Anunoby

Delivers Clean Shooting Line Saturday
Mikal Bridges

Fills Box Score in Game 3 Win
Jalen Brunson

Pushes Knicks Closer to NBA Finals
Orlando Magic

Magic Interview Jeff Van Gundy for Head-Coaching Position
Phillip Danault

Extends Point Streak to Three Games
Josh Anderson

Nets Two Goals in Painful Loss
Jalen Chatfield

Delivers Two Assists in Crucial Win
Mark Jankowski

Contributes Two Assists in Game 2 Victory
Eric Robinson

Scores in Second Consecutive Game
Nikolaj Ehlers

Tallies Two Goals as Hurricanes Bounce Back Saturday
Giannis Antetokounmpo

Magic Reportedly Have Giannis Antetokounmpo on Their Radar
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Nazem Kadri

Contributes an Assist in Losing Effort
Ross Colton

Nets Lone Avalanche Goal Friday Night
Rasmus Andersson

Extends Assist Streak to Four Games
Pavel Dorofeyev

Focuses on Playmaking in Friday's Win
Jack Eichel

Enjoys Multi-Point Outing in Game 2 Win Friday
Ivan Barbashev

Amasses Three Points as Golden Knights Grab 2-0 Series Lead
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Robby Snelling

Will Undergo Tommy John Surgery
Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
CFB

Lincoln Riley Believes USC is Ready for Playoff Run
CFB

Notre Dame-Stanford Rivalry Renewed Through 2028
CFB

Ahmad Hardy Says He's "Back to the Road to Success"
CFB

Texas Tech Graduate Judge Recuses Himself from Brendan Sorsby Case
CFB

UCLA Tackle Jordan Davis Officially Eligible for 2026 Season
CFB

Bret Bielema Supports Significant College Football Playoff Expansion
Michael Thorbjornsen

Brings High Upside to CJ Cup Byron Nelson
Luke List

Carrying Poor Form Into CJ Cup Byron Nelson
Tom Kim

Hoping to Build on Strong Myrtle Beach Finish
PGA

Sungjae Im Brings Upside to TPC Craig Ranch
Billy Horschel

Looking for Turnaround at CJ Cup Byron Nelson
Adam Hadwin

Difficult to Trust at TPC Craig Ranch
Tony Finau

Looking for Consistency at TPC Craig Ranch
Luke Clanton

Searching for Form at CJ Cup Byron Nelson
Aaron Rai

Withdraws From CJ Cup Byron Nelson
Wyndham Clark

Can Wyndham Clark Find Form at CJ Cup?
Si Woo Kim

Looks To Stay Hot at CJ Cup
Scottie Scheffler

to Defend CJ Cup Byron Nelson Title This Week
Jordan Spieth

Looking For Victory at TPC Craig Ranch
PGA

Matti Schmid Looks to Keep Recent Momentum Going at TPC Craig Ranch
Brooks Koepka

a High-Upside Play at CJ Cup Byron Nelson
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Gerrit Cole

to Make Season Debut on Friday Against Rays
RANKINGS
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1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF