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DraftKings Daily Fantasy Football Lineup Picks (Wild Card Round): NFL DFS Advice

RotoBallers, welcome to Wild Card Round of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for the Wild Card Round of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Wild Card Round!

Be sure to check all of our fantasy football rankings for 2025:

 

DraftKings Quarterbacks - Wild Card Round DFS Picks

Jared Goff - LAR vs ATL (DK - $6,700)

Goff is one of the top options on the slate this weekend, and with how well the Rams offense has been playing, it's tough to fade him in either format. If you are going to be rolling out multiple lineups, then you will want some exposure to him. He has multiple touchdowns in five straight games, and is up against the Falcons who have the 19th DVOA against the pass. Goff is looking to be one of the safer options at quarterback, who also has plenty of upside. We have seen the Rams put up points in a hurry, so you should feel very confident with rostering him.

Blake Bortles - JAX vs BUF (DK - $6,000)

Bortles is in a sneaky good spot this weekend, which may give him some upside in GPPs. He has multiple touchdowns in four of his last five weeks, and is now up against the Bills who have the 12th DVOA against the pass. We know the Jaguars will lean on their running game in this game, since the Bills have the 30th DVOA against the run. Since they are so bad against the run, they will likely stack the box, opening up man coverage on the outside, or single deep safety looks, giving his passing upside. More of a GPP option this weekend, as he has shown multiple touchdown upside.

 

DraftKings Running Backs - Wild Card Round DFS Picks

Todd Gurley - LAR vs ATL (DK - $9,700)

Gurley is clearly the top running back on the slate this week, and after what he did the last few weeks of the season, it's hard to fade him. He is totaling over 100 combined yards in nearly every game since the mid point of the season. He has plenty of PPR value out of the backfield, and is their main running back in all situations. The role he has in the Rams offense is massive, and with the Rams having an implied team total of 27.5 points, you have to assume he will be involved in two of those scores. He is expensive, but you really need to find a way to get up to his price.

Christian McCaffrey - CAR @ NO (DK - $6,400)

The Panthers are projected to be down in this game, which means they will likely be passing the ball to catch up. This puts McCaffrey in a spot to succeed, as he sees plenty of targets in the passing game. He has five or more targets in 14 of his 16 games this season. He does run the ball a bit, but he really isn't that effective at it, and is used more in the passing game. He is a bit cheaper then some of the top running backs, but the game script should be in his favor, opening up a nice ceiling for him.

 

DraftKings Wide Receivers -Wild Card Round DFS Picks

Julio Jones - ATL @ LAR (DK - $8,000)

Jones is the top receiver on the slate this weekend, and he seems a bit under priced. Not sure if they adjusted pricing for it only being a four game slate, but he is $500 less than what he was just three weeks ago. Anytime you can get Julio at a decreased price you really shouldn't pass him up. We know the type of ceiling he has, multiple touchdowns, and can get over 200 yards. This is a bit of a tougher match up for him, as the Rams have the 3rd DVOA against the pass, and the 12th DVOA against WR1. With that said, they game script should have the Rams up by at least one score, putting the Falcons in a spot where they need to pass, which means a lot of Julio.

Rishard Matthews - TEN @ KC (DK - $4,900)

Matthews had seen five or more targets in all but three game this season, as he is their number one receiver. The Titans offense can be very hit or miss, so Matthews makes more of a GPP option compared to cash games. The Chiefs have the 20th DVOA against the pass, and the 32nd DVOA against WR1. Matthews is in a great spot, just a matter if he can seize this opportunity and turn it into big points.

 

DraftKings Tight End - Wild Card Round DFS Pick

Travis Kelce - KC vs TEN (DK - $7,100)

Kelce is the most expensive tight end on the slate by over $2K, so if you want him, you have to find some savings elsewhere. Tight end is a spot where many people like to pay down, but with his consistency, he is worth paying up for on a short slate. He is up against the Titans, who have the 24th DVOA against tight ends. Really great spot for him, and over the course of the season, he only has four games under 10 DraftKings points.

 

DraftKings Defense - Wild Card Round DFS Pick

Los Angeles Rams vs Atlanta Falcons (DK - $2,700)

The Rams offense is cheapest of the teams who are home favorites, making them an appealing option. From a simple roster construction stand point, the Rams fit nicely into both cash and GPP builds. They have four interceptions over their last four weeks, and have 10 sacks over that same span. The Atlanta offense ins't the same it was last year, and have shown they can struggle at points, making them a nice team to attack.

 

More Weekly DFS Analysis





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REAL-TIME FANTASY NEWS

Klay Thompson

Downgraded Versus Houston
Alperen Sengün

Alperen Sengun Out Again on Saturday Evening
Tyler Herro

Will Miss Another Game on Saturday
Jimmy Butler III

Out Again on Saturday Night
Draymond Green

Ruled Out Versus Cleveland
Jose A. Ferrer

Mariners Acquire Jose A. Ferrer from the Nationals
Mason Marchment

Expected to Return Saturday
Danila Yurov

Returns From Two-Game Absence Saturday
Jesperi Kotkaniemi

Available Saturday
Harry Ford

Traded to the Nationals
Shane Pinto

to Miss Two Weeks
David Pastrnak

Misses Fifth Consecutive Game Saturday
Andrei Vasilevskiy

Remains Out Saturday
Nikita Kucherov

Out on Saturday
Jayden Reed

Activated Off Injured Reserve, Will Play in Week 14
Omarion Hampton

Activated From IR, Faces Uncertain Workload Monday Night
Cody Bellinger

Drawing Interest From the Phillies
MacKenzie Gore

Will the Nationals Trade MacKenzie Gore?
Justin Herbert

Officially Listed as Questionable for Monday Night Football
Justin Herbert

Chargers "Expecting" Justin Herbert to Play in Week 14
Yves Missi

Trending Toward Game-Time Decision
Khris Middleton

Questionable With Knee Soreness Against Hawks
Noah Clowney

On Track To Suit Up Against Pelicans
De'Anthony Melton

Questionable With Knee Management
Draymond Green

Questionable With Mid-Foot Sprain
Jimmy Butler III

Day-To-Day As Warriors Prepare For Cleveland
Mikko Rantanen

Picks Up Three Points Against Sharks
Kyle Connor

Scores in Fourth Consecutive Game
Beckett Sennecke

Notches Two Points in Friday's Win
Ryan Leonard

Suffers Upper-Body Injury Friday
Carter Hart

Day-to-Day With Lower-Body Injury
Brayden Point

Questionable for Saturday
Victor Hedman

Expected to Return Saturday
Byron Buxton

Twins Not Planning to Trade Joe Ryan, Byron Buxton
Patrick Williams

Dalen Terry Available Versus Pacers
Coby White

Returns With Minutes Restriction Friday
Ayo Dosunmu

Out Friday Against Pacers
Zach Collins

Available for Season Debut Friday
Robert Williams III

Donovan Clingan Out, Robert Williams III in for Portland Friday
Evan Mobley

Ready to Play Friday
Kristaps Porzingis

Coming Off the Bench Friday
Spencer Jones

Available Against Hawks
OG Anunoby

Returns to Knicks LIneup Friday
Tre Mann

Misses Third Consecutive Game
Ozzy Wiesblatt

to Miss 8-10 Weeks With Upper-Body Injury
Pierre-Olivier Joseph

Out With Illness Friday
Evander Kane

Doubtful for Friday
Conor Garland

Back From Two-Game Absence Friday
Thomas Harley

Could Be an Option Next Week
Mikael Granlund

Returning From 10-Game Absence Friday
John Carlson

Misses Second Consecutive Game Friday
Rome Odunze

has Fractured Foot, Labeled Week-to-Week
Sauce Gardner

Ruled Out for Sunday
Petr Yan

Looks To Reclaim Bantamweight Belt
Merab Dvalishvili

Set For His Fourth Title Defense
Joshua Van

Can Become The New Flyweight Champion
Aaron Jones Sr.

Cleared to Play in Week 14
Chris Olave

Listed as Questionable for Week 14
Alexandre Pantoja

Set For Fifth Title Defense At UFC 323
Tatsuro Taira

Looks To Win Back-To-Back Fights
Alvin Kamara

Ruled Out for Sunday
Brandon Moreno

Searches For His Third Win In A Row
Rome Odunze

Ruled Out for Week 14
Payton Talbott

A Favorite At UFC 323
Henry Cejudo

Set For His Retirement Fight
Drake London

Ruled Out vs Seattle
Jan Blachowicz

Set To Open Up UFC 323 Main Card
Lamar Jackson

Will Play on Sunday
Bogdan Guskov

Looks To Extend His Win Streak
CFB

Emmett Johnson Leaving Nebraska for 2026 NFL Draft
Dalton Kincaid

to be Questionable for Week 14
Tee Higgins

Clears Concussion Protocol, is a Full-Go for Sunday
CFB

Jam Miller Unlikely to Play in SEC Title Game
CFB

Penn State Expected to Hire Matt Campbell from Iowa State
Mike Evans

Not Quite Ready to Return This Week
Jayden Daniels

Will Start Against Vikings
Lamar Jackson

Returns to Practice, on Track to Play on Sunday
Kyler Murray

Won't Return This Year, Cardinals Non-Committal on his Future
Trey Benson

Out in Week 14; Could he Miss the Rest of the Season?
Marvin Harrison Jr.

Ruled Out for Sunday's Game
CeeDee Lamb

in the League's Concussion Protocol
CFB

Arkansas Targeting Ron Roberts for Defensive Coordinator Job
Jhostynxon Garcia

Pirates Acquire Jhostynxon Garcia From Red Sox
Cody Bellinger

Yankees Pushing Hard to Re-Sign Cody Bellinger
CFB

Penn State Eyeing Iowa State Coach Matt Campbell For Coaching Vacancy
Alex Bregman

Cubs Have Renewed Interest in Alex Bregman
CFB

Billy Napier Finalizing Deal to Become James Madison's New Head Coach
CFB

Buster Faulkner Set to Become Florida's New Offensive Coordinator
CFB

Joe Sloan Expected to be Kentucky's New Offensive Coordinator
CFB

Lane Kiffin Working to Keep Defensive Coordinator Blake Baker at LSU
CFB

Brian Daboll a Candidate for Penn State Head-Coaching Job?
Kyle Tucker

Visits With Blue Jays
Emilio Pagán

Reds Bring Back Closer Emilio Pagan on Two-Year Deal
Cedric Mullins

Rays Agree on One-Year Deal
Freddy Peralta

Brewers Considering Trading Freddy Peralta
Kyle Schwarber

Reds Serious About Adding Kyle Schwarber in Free Agency?
CFB

Brent Key Signing Five-Year Deal to Remain at Georgia Tech
CFB

Brian Hartline Expected to Land USF Head-Coaching Job
CFB

Collin Klein Expected to be Top Target for Kansas State if Head-Coach Job Opens
CFB

Chris Klieman Considering Stepping Down at Kansas State
CFB

D.J. Durkin Staying at Auburn Under Alex Golesh
CFB

Charlie Weis Jr. Permitted to Coach Ole Miss Offense in College Football Playoff
CFB

Five-Star Quarterback Jared Curtis Flips Commitment From Georgia to Vanderbilt
CFB

Florida Hiring Brad White as Defensive Coordinator
Kyle Schwarber

Giants Have Checked in on Kyle Schwarber
Willson Contreras

Willing to Waive his Full No-Trade Clause?
Edwin Díaz

Mets Still Interested in Re-Signing Edwin Diaz
Devin Williams

Agrees to Three-Year Deal With Mets
Cole Ragans

Red Sox Targeting Cole Ragans in a Trade?
CFB

Kentucky Hires Oregon Offensive Coordinator Will Stein As Head Coach
CFB

Kalani Sitake the Top Target for Penn State Coaching Job
CFB

Josh Heupel Says He's Not a Candidate for Penn State Head Coach Job

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