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DraftKings Daily Fantasy Football Lineup Picks (Week 4): NFL DFS Advice

Welcome to RotoBaller's Daily Fantasy football DraftKings lineup picks for Week 4 of the NFL season. In this article, I, Jason Bales, will be taking you, the reader, through the best DraftKings DFS plays of the week for this upcoming Sunday.

These DraftKings lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 4. Good luck with your DraftKings DFS lineups!

Editor's Note: If you like DraftKings, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Be sure to check all of our fantasy football rankings for 2025:

 

DraftKings Quarterbacks - Week 4 DFS Picks

Philip Rivers (vs NO, $6,900)

Philip Rivers is the best quarterback option on the board this week. He gets a fantastic matchup against the New Orleans Saints, a team that had a horrible defense to start the season and is currently dealing with multiple injuries in their secondary. The San Diego Chargers are going to pick them apart with their ariel attack. Rivers has been throwing the ball around 40 times per game, and if the Saints turn this game into a shootout, which is likely, he should throw the ball at least 40-45 times. This will be a very high-scoring affair, forcing Rivers to hit value. He may be limited as far as his offensive toys go, but the Chargers' quarterback will find a way to get it done.

 

DraftKings Running Backs - Week 4 DFS Picks

Le'Veon Bell (vs KC, $7,500)

The Pittsburgh Steelers are going to shove the ball down Le'Veon Bell's throat this week. Whether he likes it or not, he is going to touch the ball upwards of 30-40 times. At least, he should. The Kansas City Chiefs have not been great at stopping the run, and the Steelers' offense needs a little bit of stability after last week's terrible loss to the Philadelphia Eagles. Bell has yet to play this season, but everyone knows that he is the best running back in the league. He has something to prove tonight, and that is exactly what he will do. Pay up for his high price tag. There are plenty of value plays to make it work.

Carlos Hyde (vs DAL, $4,200)

Even with Le'Veon Bell back in action this week, Carlos Hyde is the most valuable running back on the board. He gets a solid matchup against the Dallas Cowboys, a team that struggles defensively, and he has been great all season so far. In two of his first three games, he has over 20 fantasy points. Finding the end zone four times, Hyde is a high-upside, low-priced fantasy steal this week. He is part of Chip Kelly's fast-paced offense now, and it looks like he is going to excel. There is no reason to avoid him. Roster him in both 50/50 and touranment lineups without hesitation.

 

DraftKings Wide Receivers - Week 4 DFS Picks

Tyrell Williams (vs NO, $4,400)

It is always a great idea to pair a wide receiver with a quarterback in daily fantasy football. It increases the upside of the lineup. Even before Keenan Allen went down with an injury, Williams was targeted five times. That was week one. In week three, he was targeted nine times, and he is quickly becoming a bigger part of the San Diego Chargers' offense. He is going to start finding the end zone more frequently, as long as his targets stay up. In his last two starts, he has 12.9 and 15.1 fantasy points, making him a great play in both 50/50 contests and tournaments. He is very likely to hit value.

Quincy Enunwa (vs SEA, $4,400)

Quincy Enunwa is having a great season so far, as far as fantasy is concerned. With 25 targets in three weeks, he is averaging over 13 fantasy points per game. For his price tag, that is solid. Eric Decker is out this week with a partially torn rotator cuff, so Enunwa is going to continue to see more targets. In week three, he had 11, which was one more than Brandon Marshall. Marshall is going to get shadowed and likely double-covered by the Seattle Seahawks' best members of the secondary, leaving Enunwa room to work. As long as he makes the most of his targets, Enunwa will at least hit value.

 

DraftKings Tight Ends - Week 4 DFS Picks

Zach Miller (vs DET, $2,700)

This is the easiest recommendation of the week. Zach Miller is entirely too cheap on DraftKings right now. He gets a great matchup against the Detroit Lions, and the Chicago Bears have to start Brian Hoyer with Jay Cutler currently dealing with an injury. Hoyer loves to check down to the tight end, evidenced by his nine targets, eight receptions, and two touchdowns last week against the Dallas Cowboys. He posted over 25 fantasy points. His price tag last week was higher than his price tag this week. Miller is poised to have a great season, especially if Cutler remains injured. He will save quite a bit of salary cap space, as well. Use him in both 50/50 contests and tournaments.

 




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REAL-TIME FANTASY NEWS

A.J. Brown

Continues Dominant Stretch With 100 Yards in Monday Night Loss
Saquon Barkley

Rips Off Long Touchdown Run in Monday Night Loss
Shohei Ohtani

to be Used More as Traditional Starting Pitcher Next Year
Yordan Alvarez

to Become Full-Time DH in 2026?
Mason Miller

Padres Plan to Keep Mason Miller in the Bullpen
Ranger Suárez

Orioles Interested in Signing Ranger Suarez
Anthony Volpe

Yankees Don't Expect Anthony Volpe to be Ready in April
Gerrit Cole

Targeting a Return in May/June
Riley Leonard

"Week-to-Week" With Strained Knee
NFL

Patriots-Ravens Week 16 Game Flexed to Sunday Night Football
Omarion Hampton

Making his Return on Monday Night
CFB

Heisman Trophy Finalists Announced on Monday
Justin Herbert

Officially Active Against Eagles
Indianapolis Colts

Colts Bringing Philip Rivers in for a Workout
Justin Herbert

Expected to Start on Monday Night
Trey Benson

Cardinals Could Hold Trey Benson Out Another Week
Keegan Murray

Available on Monday
Anthony Edwards

Set to Suit Up Monday
Jack Roslovic

Not Close to Returning
Dennis Schröder

Dennis Schroder Sidelined Again on Monday
Jake Walman

to Miss at Least Two More Weeks
Berkly Catton

Out Week-to-Week
Franz Wagner

Likely to Miss 2-4 Weeks
Nils Hoglander

Set for Season Debut Monday
Elias Pettersson

Misses Second Straight Game
Logan Cooley

Out Indefinitely
Brayden Point

Nikita Kucherov, Brayden Point Back for Lightning Monday
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Anthony Hill Jr. Declaring for 2026 NFL Draft
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Ryan Walters a Candidate for Tennessee Defensive Coordinator Job?
Trey Hendrickson

Set for Core-Muscle Surgery, Expected to Miss Around Six Weeks
Drake London

Considered Day-to-Day Going into Thursday Night
Jayden Daniels

No Long-Term Concerns for Jayden Daniels
Zach Ertz

MRI Confirms Season-Ending Torn ACL for Zach Ertz
Tee Higgins

Back in the Concussion Protocol
Riley Leonard

Week 15 Status Uncertain Due to Knee Injury
Mike Evans

Could Return on Thursday Night
De'Von Achane

May Require Rest This Week
Daniel Jones

' Season Over With Torn Achilles
Rory McIlroy

Ends 2025 as the Year's Most Unburdened Player
Aaron Rai

Needs to Figure Out Putting Woes This Offseason
Jordan Spieth

Plays Better on Paper in 2025 Than Results Show
Shedeur Sanders

Will Start for Browns the Rest of the Season
PGA

Chris Gotterup Needs to Find Better Touch and Consistency This Offseason
Hideki Matsuyama

Ends 2025 Season With a Bookend Victory
CFB

Tennessee Fires Defensive Coordinator Tim Banks
Scottie Scheffler

Comes Up Just Shy of Hero World Challenge Victory
Jordan Poole

Remains Sidelined on Monday
Merab Dvalishvili

Drops A Decision At UFC 323
Herbert Jones

Tagged as Questionable Against Spurs
Petr Yan

Reclaims Bantamweight Title
CeeDee Lamb

Progressing Well After Concussion
Stephon Castle

has a Chance to Return on Monday
Alexandre Pantoja

Era Ends With Gruesome Injury
Joshua Van

Becomes Second-Youngest UFC Champion
Dillon Brooks

Iffy for Monday Night
Brandon Moreno

Suffers His First TKO Loss
Brandon Moreno

Tatsuro Taira Becomes First Fighter To Finish Brandon Moreno
Garrett Wilson

No Timetable Yet for Garrett Wilson's Return
Henry Cejudo

Payton Talbott Retires Henry Cejudo
Henry Cejudo

Retires After UFC 323 Loss
Jan Blachowicz

Bogdan Guskov Vs. Jan Blachowicz Ends In A Majority Draw
Jan Blachowicz

And Bogdan Guskov Fight To Majority Draw
Dennis Schröder

Dennis Schroder Could Return on Monday Night
Keegan Murray

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Texas RB CJ Baxter Entering Transfer Portal
Mark Stone

Records Two Assists in Sunday's Win
Carter Hart

Defeats Rangers Sunday
Cutter Gauthier

Delivers Two Assists Sunday
Leo Carlsson

Nets Two Goals in Blowout Win
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Posts First Shutout of the Season
Brayden Schenn

Leads Blues to Victory Sunday
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Bags Three Points in Impressive Road Victory
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Jeff Kent Elected to Baseball Hall of Fame
Ketel Marte

Red Sox Interested in Trading for Ketel Marte
Kyle Schwarber

Pirates Make Four-Year Offer to Kyle Schwarber
CFB

Mississippi State, Rice Accept Bowl Bids as 5-7 Teams
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Auburn, Florida State, Baylor Among Teams to Decline Bowl Bids
Paul George

Available on Sunday Evening
Joel Embiid

Available Against Lakers
Lauri Markkanen

Ruled Out Versus OKC
Jimmy Butler III

Officially Active on Sunday Night
CFB

Rob Aurich Set to Become Nebraska's Defensive Coordinator
LeBron James

Available Versus Philadelphia
MON

Samuel Montembeault Ruled Out for Sunday
Carter Hart

Available Against Rangers Sunday
Ryan Leonard

to Miss "Extended Period of Time"
John Carlson

a Game-Time Decision Sunday
Jordan Kyrou

Unavailable Against Canadiens
Matt Duchene

Set to Return Against Penguins
Pyotr Kochetkov

Back for Hurricanes Sunday
CFB

Notre Dame Opting Out of Postseason Amid College Football Playoff Exclusion
Karl-Anthony Towns

Ruled Out Against Orlando
Draymond Green

Remains on the Shelf Versus Chicago
Jimmy Butler III

Expected to Return on Sunday
Immanuel Quickley

Now Probable Versus Boston
Shai Gilgeous-Alexander

Will Miss First Game of the Year on Sunday
Joel Embiid

Upgraded to Probable Against Lakers
CFB

Kendal Briles a Candidate for South Carolina Offensive Coordinator Job
CFB

James Madison Playoff-Bound After Duke Wins ACC Title?
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Notre Dame, Miami, Alabama on College Football Playoff Bubble
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Brent Pry Could Return to Virginia Tech as Defensive Coordinator
Jose A. Ferrer

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Harry Ford

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Cody Bellinger

Drawing Interest From the Phillies
MacKenzie Gore

Will the Nationals Trade MacKenzie Gore?
Byron Buxton

Twins Not Planning to Trade Joe Ryan, Byron Buxton
Petr Yan

Looks To Reclaim Bantamweight Belt
Merab Dvalishvili

Set For His Fourth Title Defense
Joshua Van

Can Become The New Flyweight Champion
Alexandre Pantoja

Set For Fifth Title Defense At UFC 323
Tatsuro Taira

Looks To Win Back-To-Back Fights
Brandon Moreno

Searches For His Third Win In A Row
Payton Talbott

A Favorite At UFC 323
Henry Cejudo

Set For His Retirement Fight
Jan Blachowicz

Set To Open Up UFC 323 Main Card
Bogdan Guskov

Looks To Extend His Win Streak
CFB

Emmett Johnson Leaving Nebraska for 2026 NFL Draft
CFB

Jam Miller Unlikely to Play in SEC Title Game
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Penn State Expected to Hire Matt Campbell from Iowa State
CFB

Arkansas Targeting Ron Roberts for Defensive Coordinator Job
Jhostynxon Garcia

Pirates Acquire Jhostynxon Garcia From Red Sox
Cody Bellinger

Yankees Pushing Hard to Re-Sign Cody Bellinger
CFB

Penn State Eyeing Iowa State Coach Matt Campbell For Coaching Vacancy
Alex Bregman

Cubs Have Renewed Interest in Alex Bregman
CFB

Billy Napier Finalizing Deal to Become James Madison's New Head Coach
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Buster Faulkner Set to Become Florida's New Offensive Coordinator
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Joe Sloan Expected to be Kentucky's New Offensive Coordinator
Kyle Tucker

Visits With Blue Jays
Emilio Pagán

Reds Bring Back Closer Emilio Pagan on Two-Year Deal
Cedric Mullins

Rays Agree on One-Year Deal
Freddy Peralta

Brewers Considering Trading Freddy Peralta

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