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DraftKings Daily Fantasy Football Lineup Picks (Week 4): NFL DFS Advice

Welcome to RotoBaller's Daily Fantasy football DraftKings lineup picks for Week 4 of the NFL season. In this article, I, Jason Bales, will be taking you, the reader, through the best DraftKings DFS plays of the week for this upcoming Sunday.

These DraftKings lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 4. Good luck with your DraftKings DFS lineups!

Editor's Note: If you like DraftKings, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Be sure to check all of our fantasy football rankings for 2025:

 

DraftKings Quarterbacks - Week 4 DFS Picks

Philip Rivers (vs NO, $6,900)

Philip Rivers is the best quarterback option on the board this week. He gets a fantastic matchup against the New Orleans Saints, a team that had a horrible defense to start the season and is currently dealing with multiple injuries in their secondary. The San Diego Chargers are going to pick them apart with their ariel attack. Rivers has been throwing the ball around 40 times per game, and if the Saints turn this game into a shootout, which is likely, he should throw the ball at least 40-45 times. This will be a very high-scoring affair, forcing Rivers to hit value. He may be limited as far as his offensive toys go, but the Chargers' quarterback will find a way to get it done.

 

DraftKings Running Backs - Week 4 DFS Picks

Le'Veon Bell (vs KC, $7,500)

The Pittsburgh Steelers are going to shove the ball down Le'Veon Bell's throat this week. Whether he likes it or not, he is going to touch the ball upwards of 30-40 times. At least, he should. The Kansas City Chiefs have not been great at stopping the run, and the Steelers' offense needs a little bit of stability after last week's terrible loss to the Philadelphia Eagles. Bell has yet to play this season, but everyone knows that he is the best running back in the league. He has something to prove tonight, and that is exactly what he will do. Pay up for his high price tag. There are plenty of value plays to make it work.

Carlos Hyde (vs DAL, $4,200)

Even with Le'Veon Bell back in action this week, Carlos Hyde is the most valuable running back on the board. He gets a solid matchup against the Dallas Cowboys, a team that struggles defensively, and he has been great all season so far. In two of his first three games, he has over 20 fantasy points. Finding the end zone four times, Hyde is a high-upside, low-priced fantasy steal this week. He is part of Chip Kelly's fast-paced offense now, and it looks like he is going to excel. There is no reason to avoid him. Roster him in both 50/50 and touranment lineups without hesitation.

 

DraftKings Wide Receivers - Week 4 DFS Picks

Tyrell Williams (vs NO, $4,400)

It is always a great idea to pair a wide receiver with a quarterback in daily fantasy football. It increases the upside of the lineup. Even before Keenan Allen went down with an injury, Williams was targeted five times. That was week one. In week three, he was targeted nine times, and he is quickly becoming a bigger part of the San Diego Chargers' offense. He is going to start finding the end zone more frequently, as long as his targets stay up. In his last two starts, he has 12.9 and 15.1 fantasy points, making him a great play in both 50/50 contests and tournaments. He is very likely to hit value.

Quincy Enunwa (vs SEA, $4,400)

Quincy Enunwa is having a great season so far, as far as fantasy is concerned. With 25 targets in three weeks, he is averaging over 13 fantasy points per game. For his price tag, that is solid. Eric Decker is out this week with a partially torn rotator cuff, so Enunwa is going to continue to see more targets. In week three, he had 11, which was one more than Brandon Marshall. Marshall is going to get shadowed and likely double-covered by the Seattle Seahawks' best members of the secondary, leaving Enunwa room to work. As long as he makes the most of his targets, Enunwa will at least hit value.

 

DraftKings Tight Ends - Week 4 DFS Picks

Zach Miller (vs DET, $2,700)

This is the easiest recommendation of the week. Zach Miller is entirely too cheap on DraftKings right now. He gets a great matchup against the Detroit Lions, and the Chicago Bears have to start Brian Hoyer with Jay Cutler currently dealing with an injury. Hoyer loves to check down to the tight end, evidenced by his nine targets, eight receptions, and two touchdowns last week against the Dallas Cowboys. He posted over 25 fantasy points. His price tag last week was higher than his price tag this week. Miller is poised to have a great season, especially if Cutler remains injured. He will save quite a bit of salary cap space, as well. Use him in both 50/50 contests and tournaments.

 




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REAL-TIME FANTASY NEWS

Sam Merrill

and Craig Porter Jr. Out Monday
RJ Barrett

Sidelined Versus Cleveland
Ridly Greig

Still Out Monday
De'Andre Hunter

Out Versus Raptors
Baker Mayfield

Dealing With Low-Grade Shoulder Sprain
Thomas Chabot

Misses Monday's Matchup
Mitchell Robinson

Under the Weather, Out Versus Brooklyn
Kirill Marchenko

Out Monday
Jarrett Allen

Out of Action Again on Monday
J.T. Miller

Unavailable Monday
Andrew Wiggins

Norman Powell Out on Monday Night
Brayden Point

Out Against Flyers
Darius Garland

Sidelined on Monday
Nikita Kucherov

Good to Go Monday
Chris Godwin

Buccaneers Plan to "Ramp Up" Chris Godwin's Usage
Colorado Rockies

Warren Schaeffer to Stick Around as Rockies Manager in 2026
Ashton Jeanty

Ankle Injury isn't Severe
Jayden Daniels

to Practice This Week, Considered a Long Shot for Week 13
C.J. Stroud

Remains in Concussion Protocol
Mike Evans

Could Return Before End of Regular Season
J.J. McCarthy

in Concussion Protocol
Tyrod Taylor

to Remain the Jets' Starting QB
Shedeur Sanders

to Make Another Start for Browns in Week 13
Tee Higgins

Won't Play on Thanksgiving
Joe Burrow

Bengals Expect Joe Burrow to Play on Thursday
Baker Mayfield

Not Being Ruled Out for Week 13
CFB

Chris Bell Out for Rivalry Matchup Against Kentucky
New York Giants

Giants Fire Defensive Coordinator Shane Bowen
Tee Higgins

in the Concussion Protocol
Scott Wedgewood

Gives Avalanche Second Consecutive Shutout
Macklin Celebrini

Makes History During Multi-Point Performance
Joey Daccord

Posts Shutout in Losing Effort
David Rittich

Keeps Kraken Quiet
Jesper Wallstedt

Picks Up Third Shutout of the Season
Rasmus Andersson

Extends Point Streak With Three Assists
Davante Adams

Catches Two Touchdowns in Sunday Night Win
Baker Mayfield

has Sprained Shoulder, Will Undergo MRI Monday
Las Vegas Raiders

Raiders Fire Offensive Coordinator Chip Kelly
Ryan Helsley

Tigers Eyeing Ryan Helsley as a Starter
Quinshon Judkins

Salvages his Day With Two Trips to the End Zone
Alvin Kamara

Dealing With MCL Sprain, Timetable Unclear
Michael Wilson

has Double-Digit Catches, Over 100 Yards for Second Straight Week
Baker Mayfield

Doubtful to Return on Sunday Night With Shoulder Injury
Dan Hooker

Suffers Second-Round Submission Loss
Marcus Semien

Shipped to the Mets on Sunday
Arman Tsarukyan

Gets Submission Win
Brandon Nimmo

Traded to Texas
Belal Muhammad

Loses Back-to-Back Fights
Aaron Gordon

Sidelined 4-6 Weeks with Hamstring Strain
Belal Muhammad

Ian Machado Garry Outpoints Belal Muhammad
Alonzo Menifield

Suffers First-Round Knockout Loss
Volkan Oezdemir

Gets Back In The Win Column
Jack Hermansson

Gets Knocked Out
Jack Hermansson

Myktybek Orolbai Knocks Out Jack Hermansson
Shamil Gaziev

Suffers First-Round Knockout Loss
Waldo Cortes-Acosta

Shines At UFC Qatar
Dereck Lively II

Out with Foot Issue Again
Tagir Ulanbekov

Suffers Third-Round Submission Loss
Anthony Davis

Doubtful With Calf Strain Against Miami
Kyoji Horiguchi

Makes Triumphant UFC Return
MON

Alexandre Texier Joins Canadiens
Goga Bitadze

a Very Late Scratch on Sunday Night
Ryan Dunn

Ruled Out with Wrist Sprain
Jason Dickinson

Returns to Action Sunday
Elias Lindholm

Activated From Injured Reserve
Mikko Rantanen

Suspended for One Game
Neal Pionk

Sustains Lower-Body Injury Sunday
Donovan Clingan

Upgraded to Available vs. Thunder
Jean-Gabriel Pageau

Out Week-to-Week
Robert Williams III

Sidelined Against Thunder
Anthony Black

Entering the Starting Lineup Versus Boston
Alexander Romanov

Out 5-6 Months Due to Shoulder Surgery
Goga Bitadze

Getting the Start on Sunday Night
Bogdan Bogdanović

Bogdan Bogdanovic Remains Out Sunday
Ryan Kalkbrenner

Sidelined on Sunday Evening
Tre Mann

Returns to Action Sunday
Wendell Carter Jr.

Ruled Out on Sunday Night
Luke Kennard

Misses Sunday's Contest
Sidney Crosby

Records 500th Multi-Point Game
Mackenzie Blackwood

Posts 35-Save Shutout
Adolis García

Rangers Non-Tender Adolis Garcia on Friday
CFB

Beau Pribula Expected to Start Against Oklahoma
Dan Hooker

An Underdog At UFC Qatar
Arman Tsarukyan

Looks To Extend His Win Streak
Ian Machado Garry

A Favorite At UFC Qatar
Belal Muhammad

Looks To Bounce Back
Alonzo Menifield

Looks For His Third Consecutive Win
Volkan Oezdemir

Looks To Get Back In The Win Column
Myktybek Orolbai

Looks To Win Back-To-Back Fights
Jack Hermansson

Makes His Welterweight Debut
Kyoji Horiguchi

Returns To The UFC
Elly De La Cruz

Played Through Partially Torn Quad to End 2025
Tarik Skubal

Tigers "Doubtful" to Trade Tarik Skubal
Raisel Iglesias

Returning to the Braves on One-Year Deal
Sahith Theegala

Looking to Continue Fall Run at RSM Classic
Stephan Jaeger

Looking to Bounce Back at RSM Classic
Tom Hoge

Looking to Regain Form at RSM Classic
Joe Highsmith

Searching for Turnaround at RSM Classic
Adam Hadwin

Looking to Build on T11 Finish in Bermuda
Austin Eckroat

Searching for Momentum at RSM Classic
Joel Dahmen

Trying to Find Form at the RSM Classic
CFB

Garrett Nussmeier Doubtful to Play Against Western Kentucky
Michael Thorbjornsen

Hopes to End 2025 Campaign With Another Solid Finish
Andrew Novak

Looks to End 2025 Season on High Note at RSM Classic
Harry Higgs

Teetering for PGA Tour Card in 2026
PGA

Nico Echavarria has the Potential to Contend at the RSM Classic
Sam Stevens

Finishing Out Year in Georgia
Seamus Power

Playing Better at the Right Time
Beau Hossler

Roller Coaster Comes to Saint Simons Island
Quade Cummins

The Time is Now for Quade Cummins in Georgia
Austin Cook

Needs a Win at the RSM Classic
Cameron Champ

on the PGA Tour Card Bubble
Grayson Rodriguez

Shipped to Angels
Taylor Ward

Orioles Acquire Taylor Ward From Angels
Shota Imanaga

Accepts Cubs Qualifying Offer
Brandon Woodruff

Returning to Milwaukee in 2026
Denny McCarthy

Looking For Another Solid Finish at RSM Classic
Si Woo Kim

Looking To Use Current Momentum to Flip Script at RSM Classic
Mackenzie Hughes

a Good Bounce-Back Candidate at RSM Classic
Harris English

Making 14th Start at This Week's RSM Classic
Konnor Griffin

Could Compete for Starting Shortstop Job in 2026
Gleyber Torres

Accepts Tigers Qualifying Offer

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP