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DraftKings Daily Fantasy Football Lineup Picks (Week 4): NFL DFS Advice

Welcome to RotoBaller's Daily Fantasy football DraftKings lineup picks for Week 4 of the NFL season. In this article, I, Jason Bales, will be taking you, the reader, through the best DraftKings DFS plays of the week for this upcoming Sunday.

These DraftKings lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 4. Good luck with your DraftKings DFS lineups!

Editor's Note: If you like DraftKings, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Be sure to check all of our fantasy football rankings for 2025:

 

DraftKings Quarterbacks - Week 4 DFS Picks

Philip Rivers (vs NO, $6,900)

Philip Rivers is the best quarterback option on the board this week. He gets a fantastic matchup against the New Orleans Saints, a team that had a horrible defense to start the season and is currently dealing with multiple injuries in their secondary. The San Diego Chargers are going to pick them apart with their ariel attack. Rivers has been throwing the ball around 40 times per game, and if the Saints turn this game into a shootout, which is likely, he should throw the ball at least 40-45 times. This will be a very high-scoring affair, forcing Rivers to hit value. He may be limited as far as his offensive toys go, but the Chargers' quarterback will find a way to get it done.

 

DraftKings Running Backs - Week 4 DFS Picks

Le'Veon Bell (vs KC, $7,500)

The Pittsburgh Steelers are going to shove the ball down Le'Veon Bell's throat this week. Whether he likes it or not, he is going to touch the ball upwards of 30-40 times. At least, he should. The Kansas City Chiefs have not been great at stopping the run, and the Steelers' offense needs a little bit of stability after last week's terrible loss to the Philadelphia Eagles. Bell has yet to play this season, but everyone knows that he is the best running back in the league. He has something to prove tonight, and that is exactly what he will do. Pay up for his high price tag. There are plenty of value plays to make it work.

Carlos Hyde (vs DAL, $4,200)

Even with Le'Veon Bell back in action this week, Carlos Hyde is the most valuable running back on the board. He gets a solid matchup against the Dallas Cowboys, a team that struggles defensively, and he has been great all season so far. In two of his first three games, he has over 20 fantasy points. Finding the end zone four times, Hyde is a high-upside, low-priced fantasy steal this week. He is part of Chip Kelly's fast-paced offense now, and it looks like he is going to excel. There is no reason to avoid him. Roster him in both 50/50 and touranment lineups without hesitation.

 

DraftKings Wide Receivers - Week 4 DFS Picks

Tyrell Williams (vs NO, $4,400)

It is always a great idea to pair a wide receiver with a quarterback in daily fantasy football. It increases the upside of the lineup. Even before Keenan Allen went down with an injury, Williams was targeted five times. That was week one. In week three, he was targeted nine times, and he is quickly becoming a bigger part of the San Diego Chargers' offense. He is going to start finding the end zone more frequently, as long as his targets stay up. In his last two starts, he has 12.9 and 15.1 fantasy points, making him a great play in both 50/50 contests and tournaments. He is very likely to hit value.

Quincy Enunwa (vs SEA, $4,400)

Quincy Enunwa is having a great season so far, as far as fantasy is concerned. With 25 targets in three weeks, he is averaging over 13 fantasy points per game. For his price tag, that is solid. Eric Decker is out this week with a partially torn rotator cuff, so Enunwa is going to continue to see more targets. In week three, he had 11, which was one more than Brandon Marshall. Marshall is going to get shadowed and likely double-covered by the Seattle Seahawks' best members of the secondary, leaving Enunwa room to work. As long as he makes the most of his targets, Enunwa will at least hit value.

 

DraftKings Tight Ends - Week 4 DFS Picks

Zach Miller (vs DET, $2,700)

This is the easiest recommendation of the week. Zach Miller is entirely too cheap on DraftKings right now. He gets a great matchup against the Detroit Lions, and the Chicago Bears have to start Brian Hoyer with Jay Cutler currently dealing with an injury. Hoyer loves to check down to the tight end, evidenced by his nine targets, eight receptions, and two touchdowns last week against the Dallas Cowboys. He posted over 25 fantasy points. His price tag last week was higher than his price tag this week. Miller is poised to have a great season, especially if Cutler remains injured. He will save quite a bit of salary cap space, as well. Use him in both 50/50 contests and tournaments.

 




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REAL-TIME FANTASY NEWS

Lauri Markkanen

Available Friday Night
LaMelo Ball

Sidelined for Friday
Tyrese Maxey

Dealing With Illness But Expected to Play Friday
Nique Clifford

to Start Thursday
Kristaps Porzingis

Out of Action Versus Pistons Friday
Joel Embiid

Probable Ahead of Friday's Matchup With Pacers
Ryan Leonard

to Miss 3-4 Weeks
Mats Zuccarello

Lands on Injured Reserve
Timo Meier

Takes Leave of Absence
Draymond Green

Ruled Out for Friday Versus Timberwolves
Thatcher Demko

Back in Canucks Crease Thursday
Josh Norris

Out on Thursday
Boone Jenner

Rejoins Blue Jackets Lineup Thursday
Stephen Curry

Off Injury Report for Friday's Matchup With Minnesota
Victor Hedman

Placed on Injured Reserve
Charlie McAvoy

Set to Return Thursday
Philip Rivers

Colts Prepping Philip Rivers to Start in Week 15?
John Konchar

Will Undergo Thumb Surgery
Zach Edey

Out at Least Four Weeks
CFB

Bryce Underwood Could Leave Michigan Without Buyout
Mike Evans

Expected to Play Thursday, But Only on Key Downs?
Fernando Tatis Jr.

Padres Not Considering Trading Fernando Tatis Jr.
Tarik Skubal

Tigers Engaged in "Serious Talks" Around Trading Tarik Skubal at the Winter Meetings
Josh Jacobs

Calling Himself Day-to-Day
CFB

Chris Brazzell II Declaring for NFL Draft
CeeDee Lamb

on Track to Play on Sunday Night
CFB

Fernando Mendoza Named AP College Football Player of the Year
Raisel Iglesias

to Remain the Braves Closer
Robert Suarez

Agrees on Three-Year Deal With Braves
T.J. Watt

Could Miss Monday's Game With a Lung Issue
Trey Hendrickson

Moved to Injured Reserve
Josh Jacobs

Likely to Miss a Second Straight Practice
De'Von Achane

to Start the Week as Limited in Practice
CFB

Sherrone Moore Remains in Police Custody
CFB

Joe Klanderman Joining Baylor Coaching Staff
Alex DeBrincat

Extends Scoring Streak With Three-Point Effort
Dylan Guenther

Lights the Lamp Twice Wednesday
CFB

Kentucky Hiring Jay Bateman as Next Defensive Coordinator
Sam Bennett

Tallies Three Points Against Mammoth
Vince Dunn

Caps Off Three-Point Performance With Overtime Winner
Spencer Knight

Stops Rangers From Scoring Wednesday
Simon Edvinsson

Makes Early Exit Wednesday
Jared McCann

Injured in Wednesday's Win
Donovan Clingan

Misses Third Consecutive Game
Jrue Holiday

Still Out Thursday
AJ Green

Iffy for Thursday
Dennis Schröder

Dennis Schroder Likely to Remain Out Thursday
Zach LaVine

Out Thursday With Thumb Injury
Alperen Sengün

Alperen Sengun Back From Two-Game Absence Thursday
Stephen Curry

on Track to Return Friday
Si Woo Kim

Closes 2025 With Strong Finish Among Putting Woes
Akshay Bhatia

Looks to Rebound in 2026 After Down Year Off the Tee
Brian Harman

2025 Season a Step Back Despite Spring Win
Sam Burns

' Elite Putting Headlines a Solid 2025 Season
Sepp Straka

Ends Stellar 2025 Campaign on a High Note
Robert MacIntyre

Closes Out a Steady 2025 Campaign
CFB

Chip Kelly Interviews for Georgia Tech Offensive Coordinator Job
CFB

Louisville Receiver Chris Bell has a Torn ACL
Davante Adams

in Good Spot for Week 15 Despite Hamstring Soreness
Devin Booker

Won't Play Against OKC
Jordan Poole

Considered Questionable for Thursday
Maxi Kleber

Sidelined for Wednesday's Matchup With Spurs
Dakota Mermis

to Miss a Month
Jake Evans

to Miss Thursday's Matchup
Elias Pettersson

Unlikely to Play Thursday
Min Woo Lee

Breaks Through to Win in Texas This Year
Nick Bjugstad

to Miss at Least Three Games
PGA

Alex Noren Wins Twice on European Tour This Year
Connor Hellebuyck

Returns to Practice
Pelle Larsson

Sidelined at Least One Week
John Carlson

Could Return Thursday
Wyndham Clark

has Up-and-Down 2025 Golf Season
CFB

Michigan Fires Head Coach Sherrone Moore
Corey Conners

Comes Close to Winning Again in Very Good 2025
Justin Rose

Turns Back the Clock in 2025
Mike Evans

Officially Questionable for Thursday Night Game
Geno Smith

Unlikely to Play in Week 15
CFB

Jim Knowles Expected to be Hired as Tennessee's Defensive Coordinator
Tyrone Tracy Jr.

"Good to Go" for Week 15
Harris English

Enjoys Solid Finish at Hero World Challenge
CeeDee Lamb

has "One or Two" Things Left to the Clear Concussion Protocol
Jayden Daniels

Commanders Not Shutting Down Jayden Daniels for the Year
CFB

Defensive Coordinator Jim Knowles Not Being Retained at Penn State
CFB

Indiana's Stephen Daley Done for Season After Post-Game Injury
Kyle Pitts Sr.

Carries Momentum and a Questionable Tag into TNF
Drake London

Won't Play on Thursday Night
Tyrone Tracy Jr.

Practicing Coming Out of the Bye Week
Garrett Wilson

Practice Window Still Hasn't Opened
Breece Hall

Out on Wednesday With Knee Soreness
Pete Alonso

Orioles Finalizing Five-Year Deal
Jayden Daniels

Ruled Out for Week 15
Cade Otton

Considered Doubtful for Thursday Night
Kyle Finnegan

Tigers, Kyle Finnegan Agree on Two-Year Deal
Bo Bichette

Red Sox Out on Bo Bichette For Now
Philadelphia Phillies

Phillies Extend Manager Rob Thomson Through 2027 Season
Michael King

the Mets' Top Rotation Target?
Ronald Acuña Jr.

Ronald Acuna Jr. Could Move Back to Leadoff Spot
CFB

Florida, Wisconsin Among Suitors for QB Transfer Kenny Minchey
CFB

Bryan Harsin, Justin Wilcox Candidates for Washington State Head Coach Job?
Edwin Díaz

Edwin Diaz Agrees to Deal With the Dodgers
Kyle Schwarber

Returning to Phillies on Five-Year Deal
CFB

Ole Miss Hiring John David Baker as Offensive Coordinator
CFB

Ty Howle the Top Target for Virginia Tech Offensive Coordinator Job
Shohei Ohtani

to be Used More as Traditional Starting Pitcher Next Year
Yordan Alvarez

to Become Full-Time DH in 2026?
Mason Miller

Padres Plan to Keep Mason Miller in the Bullpen
Ranger Suárez

Orioles Interested in Signing Ranger Suarez
Anthony Volpe

Yankees Don't Expect Anthony Volpe to be Ready in April
Gerrit Cole

Targeting a Return in May/June
CFB

Heisman Trophy Finalists Announced on Monday
CFB

Anthony Hill Jr. Declaring for 2026 NFL Draft
CFB

Ryan Walters a Candidate for Tennessee Defensive Coordinator Job?
Rory McIlroy

Ends 2025 as the Year's Most Unburdened Player
Aaron Rai

Needs to Figure Out Putting Woes This Offseason
Jordan Spieth

Plays Better on Paper in 2025 Than Results Show
PGA

Chris Gotterup Needs to Find Better Touch and Consistency This Offseason
Hideki Matsuyama

Ends 2025 Season With a Bookend Victory
CFB

Tennessee Fires Defensive Coordinator Tim Banks
Scottie Scheffler

Comes Up Just Shy of Hero World Challenge Victory
Merab Dvalishvili

Drops A Decision At UFC 323
Petr Yan

Reclaims Bantamweight Title
Alexandre Pantoja

Era Ends With Gruesome Injury
Joshua Van

Becomes Second-Youngest UFC Champion
Brandon Moreno

Suffers His First TKO Loss
Brandon Moreno

Tatsuro Taira Becomes First Fighter To Finish Brandon Moreno
Henry Cejudo

Payton Talbott Retires Henry Cejudo
Henry Cejudo

Retires After UFC 323 Loss
Jan Blachowicz

Bogdan Guskov Vs. Jan Blachowicz Ends In A Majority Draw
Jan Blachowicz

And Bogdan Guskov Fight To Majority Draw
CFB

Texas RB CJ Baxter Entering Transfer Portal
San Francisco Giants

Jeff Kent Elected to Baseball Hall of Fame
Ketel Marte

Red Sox Interested in Trading for Ketel Marte
Kyle Schwarber

Pirates Make Four-Year Offer to Kyle Schwarber

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