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DraftKings Daily Fantasy Football Lineup Picks (Week 4): NFL DFS Advice

Welcome to RotoBaller's Daily Fantasy football DraftKings lineup picks for Week 4 of the NFL season. In this article, I, Jason Bales, will be taking you, the reader, through the best DraftKings DFS plays of the week for this upcoming Sunday.

These DraftKings lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 4. Good luck with your DraftKings DFS lineups!

Editor's Note: If you like DraftKings, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Be sure to check all of our fantasy football rankings for 2025:

 

DraftKings Quarterbacks - Week 4 DFS Picks

Philip Rivers (vs NO, $6,900)

Philip Rivers is the best quarterback option on the board this week. He gets a fantastic matchup against the New Orleans Saints, a team that had a horrible defense to start the season and is currently dealing with multiple injuries in their secondary. The San Diego Chargers are going to pick them apart with their ariel attack. Rivers has been throwing the ball around 40 times per game, and if the Saints turn this game into a shootout, which is likely, he should throw the ball at least 40-45 times. This will be a very high-scoring affair, forcing Rivers to hit value. He may be limited as far as his offensive toys go, but the Chargers' quarterback will find a way to get it done.

 

DraftKings Running Backs - Week 4 DFS Picks

Le'Veon Bell (vs KC, $7,500)

The Pittsburgh Steelers are going to shove the ball down Le'Veon Bell's throat this week. Whether he likes it or not, he is going to touch the ball upwards of 30-40 times. At least, he should. The Kansas City Chiefs have not been great at stopping the run, and the Steelers' offense needs a little bit of stability after last week's terrible loss to the Philadelphia Eagles. Bell has yet to play this season, but everyone knows that he is the best running back in the league. He has something to prove tonight, and that is exactly what he will do. Pay up for his high price tag. There are plenty of value plays to make it work.

Carlos Hyde (vs DAL, $4,200)

Even with Le'Veon Bell back in action this week, Carlos Hyde is the most valuable running back on the board. He gets a solid matchup against the Dallas Cowboys, a team that struggles defensively, and he has been great all season so far. In two of his first three games, he has over 20 fantasy points. Finding the end zone four times, Hyde is a high-upside, low-priced fantasy steal this week. He is part of Chip Kelly's fast-paced offense now, and it looks like he is going to excel. There is no reason to avoid him. Roster him in both 50/50 and touranment lineups without hesitation.

 

DraftKings Wide Receivers - Week 4 DFS Picks

Tyrell Williams (vs NO, $4,400)

It is always a great idea to pair a wide receiver with a quarterback in daily fantasy football. It increases the upside of the lineup. Even before Keenan Allen went down with an injury, Williams was targeted five times. That was week one. In week three, he was targeted nine times, and he is quickly becoming a bigger part of the San Diego Chargers' offense. He is going to start finding the end zone more frequently, as long as his targets stay up. In his last two starts, he has 12.9 and 15.1 fantasy points, making him a great play in both 50/50 contests and tournaments. He is very likely to hit value.

Quincy Enunwa (vs SEA, $4,400)

Quincy Enunwa is having a great season so far, as far as fantasy is concerned. With 25 targets in three weeks, he is averaging over 13 fantasy points per game. For his price tag, that is solid. Eric Decker is out this week with a partially torn rotator cuff, so Enunwa is going to continue to see more targets. In week three, he had 11, which was one more than Brandon Marshall. Marshall is going to get shadowed and likely double-covered by the Seattle Seahawks' best members of the secondary, leaving Enunwa room to work. As long as he makes the most of his targets, Enunwa will at least hit value.

 

DraftKings Tight Ends - Week 4 DFS Picks

Zach Miller (vs DET, $2,700)

This is the easiest recommendation of the week. Zach Miller is entirely too cheap on DraftKings right now. He gets a great matchup against the Detroit Lions, and the Chicago Bears have to start Brian Hoyer with Jay Cutler currently dealing with an injury. Hoyer loves to check down to the tight end, evidenced by his nine targets, eight receptions, and two touchdowns last week against the Dallas Cowboys. He posted over 25 fantasy points. His price tag last week was higher than his price tag this week. Miller is poised to have a great season, especially if Cutler remains injured. He will save quite a bit of salary cap space, as well. Use him in both 50/50 contests and tournaments.

 




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REAL-TIME FANTASY NEWS

C.J. Stroud

in Good Position to Return in Week 13
Darius Garland

Might Play on Friday Night
Jaren Jackson Jr.

Out Against Sacramento, Santi Aldama Starting
Tyrese Maxey

Available Versus Milwaukee
Zaccharie Risacher

Cleared to Face Spurs
Kristaps Porzingis

Back in Action on Thursday
Chris Godwin

Could Play in Week 12 After Return to Full Practice
Keon Coleman

to be a Healthy Scratch Again on Thursday Night
Tarik Skubal

Tigers "Doubtful" to Trade Tarik Skubal
Jarrett Allen

Questionable for Friday
Simon Holmstrom

Ready for Action Thursday
Lars Eller

Available Thursday
Domantas Sabonis

Will Miss at Least 3-4 Weeks
Ridly Greig

Out Against Ducks
Nikola Jović

Nikola Jovic Out Against Bulls on Friday
Jake Neighbours

Back for Blues Thursday
Alexandre Sarr

Listed as Questionable for Friday Against the Raptors
TB

Nicholas Paul Available Thursday
Paul George

Set to Suit Up Thursday
Victor Hedman

Out for "Couple of Weeks"
Tyler Bertuzzi

Set to Return Thursday
Gary Harris

Added to the Injury Report as Questionable for Thursday
Daniel Jones

Added to Colts' Injury Report With Calf Issue
Andrew Wiggins

Unavailable For Friday's Matchup With Chicago
Indiana Pacers

Garrison Mathews Will Join the Pacers
Joe Burrow

Logs Second Straight Full Practice on Thursday
Dante Exum

Will Miss the Rest of the Season
Keegan Murray

Is Available For His Season Debut Thursday
Tyrese Maxey

Listed as Probable for Thursday
Domantas Sabonis

Will Not Play Thursday Against Memphis
Joel Embiid

Listed as Out for Thursday
Aaron Rodgers

Seen at Practice on Thursday
Jaylen Warren

Moving Around Well on Thursday
Bucky Irving

Will be on a Snap Count When he Returns
Jaxson Dart

Could Clear Concussion Protocol Thursday
Lamar Jackson

Returns to Thursday's Practice
Josh Jacobs

to Do Individual Drills on Thursday
Joe Mixon

Not Expected to Play This Season
Chris Godwin

Attending Thursday's Practice
Bucky Irving

Continues Practice Attendance
Rasmus Andersson

Bags Three Points Wednesday Night
Morgan Geekie

Nets Two Power-Play Goals Wednesday
Joe Burrow

Bengals Haven't Ruled Out Joe Burrow for Week 12
Connor McMichael

Posts Three Assists in Wednesday's Win
Alexander Romanov

Islanders Place Alexander Romanov on Injured Reserve
Lars Eller

to Miss Thursday's Action
Nic Dowd

Out on Thursday
Adam Lowry

Inks Extension With Jets
Jaren Jackson Jr.

Likely Out on Thursday
Zaccharie Risacher

Questionable for Thursday
Kristaps Porzingis

at Risk of Missing Another Game
Brian Thomas Jr.

Limited in Practice on Wednesday
Raisel Iglesias

Returning to the Braves on One-Year Deal
Lamar Jackson

Absent Due to Ankle Injury
Conor Garland

to Return on Thursday
Thomas Harley

to Miss Road Trip
Eetu Luostarinen

Out Week-to-Week After Barbecue Accident
Curtis Lazar

to Miss at Least Three Games
Vladimir Tarasenko

Misses Third Consecutive Game
Mikael Granlund

Remains Out Wednesday
Charlie McAvoy

Out Indefinitely After Facial Surgery
Joe Burrow

to Potentially Return in Week 12?
Aaron Rodgers

Out on Wednesday, Hopes to Practice Thursday
Jaylen Warren

Not Seen at Wednesday's Practice
Dak Prescott

Lands on Injury Report Ahead of Week 12 With Hip Injury
Sahith Theegala

Looking to Continue Fall Run at RSM Classic
Stephan Jaeger

Looking to Bounce Back at RSM Classic
Tom Hoge

Looking to Regain Form at RSM Classic
Joe Highsmith

Searching for Turnaround at RSM Classic
Adam Hadwin

Looking to Build on T11 Finish in Bermuda
Austin Eckroat

Searching for Momentum at RSM Classic
Joel Dahmen

Trying to Find Form at the RSM Classic
CFB

Garrett Nussmeier Doubtful to Play Against Western Kentucky
Michael Thorbjornsen

Hopes to End 2025 Campaign With Another Solid Finish
Andrew Novak

Looks to End 2025 Season on High Note at RSM Classic
Harry Higgs

Teetering for PGA Tour Card in 2026
PGA

Nico Echavarria has the Potential to Contend at the RSM Classic
Sam Stevens

Finishing Out Year in Georgia
Seamus Power

Playing Better at the Right Time
Beau Hossler

Roller Coaster Comes to Saint Simons Island
Quade Cummins

The Time is Now for Quade Cummins in Georgia
Austin Cook

Needs a Win at the RSM Classic
Cameron Champ

on the PGA Tour Card Bubble
Grayson Rodriguez

Shipped to Angels
Taylor Ward

Orioles Acquire Taylor Ward From Angels
Shota Imanaga

Accepts Cubs Qualifying Offer
Brandon Woodruff

Returning to Milwaukee in 2026
Denny McCarthy

Looking For Another Solid Finish at RSM Classic
Si Woo Kim

Looking To Use Current Momentum to Flip Script at RSM Classic
Mackenzie Hughes

a Good Bounce-Back Candidate at RSM Classic
Harris English

Making 14th Start at This Week's RSM Classic
Konnor Griffin

Could Compete for Starting Shortstop Job in 2026
Gleyber Torres

Accepts Tigers Qualifying Offer
CFB

Sam Leavitt Set to Enter Transfer Portal?
Jose Altuve

Undergoes Foot Surgery
Alex Bregman

Red Sox Going for Either Alex Bregman or Pete Alonso?
CFB

James Franklin to be Virginia Tech's Next Head Coach
CFB

Fernando Mendoza the Clear Heisman Trophy Favorite?
CFB

Beau Pribula Has Chance to Face Oklahoma on Saturday
Jack Della Maddalena

Gets Dominated
Islam Makhachev

Claims UFC Welterweight Belt
Zhang Weili

Gets Outclassed
Valentina Shevchenko

Wins Unanimous Decision At UFC 322
Sean Brady

Suffers First-Round TKO Loss
Michael Morales

Remains Unbeaten
Leon Edwards

Suffers Second-Round Knockout Loss
Leon Edwards

Carlos Prates Becomes The First Man To Knock Out Leon Edwards
Beneil Dariush

Suffers Brutal First-Round Knockout Loss
Beneil Dariush

Benoit Saint Denis Knocks Out Beneil Dariush In 16 Seconds
Josh Naylor

Mariners Finalizing Five-Year Contract
CFB

Jeremiah Smith, Carnell Tate Not Dealing With Long-Term Injuries
CFB

Virginia Tech Close To Naming James Franklin As Head Coach
CFB

Garrett Nussmeier Doubtful vs. Arkansas On Saturday
Edwin Díaz

Blue Jays Interested in Signing Edwin Diaz?
Jacob deGrom

Named AL Comeback Player of the Year
Ronald Acuña Jr.

Ronald Acuna Jr. Wins NL Comeback Player of the Year Award
Aroldis Chapman

Named AL Reliever of the Year
Edwin Díaz

Edwin Diaz Named NL Reliever of the Year

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