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DraftKings Daily Fantasy Football Lineup Picks (Week 4): NFL DFS Advice

Welcome to RotoBaller's Daily Fantasy football DraftKings lineup picks for Week 4 of the NFL season. In this article, I, Jason Bales, will be taking you, the reader, through the best DraftKings DFS plays of the week for this upcoming Sunday.

These DraftKings lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 4. Good luck with your DraftKings DFS lineups!

Editor's Note: If you like DraftKings, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Be sure to check all of our fantasy football rankings for 2025:

 

DraftKings Quarterbacks - Week 4 DFS Picks

Philip Rivers (vs NO, $6,900)

Philip Rivers is the best quarterback option on the board this week. He gets a fantastic matchup against the New Orleans Saints, a team that had a horrible defense to start the season and is currently dealing with multiple injuries in their secondary. The San Diego Chargers are going to pick them apart with their ariel attack. Rivers has been throwing the ball around 40 times per game, and if the Saints turn this game into a shootout, which is likely, he should throw the ball at least 40-45 times. This will be a very high-scoring affair, forcing Rivers to hit value. He may be limited as far as his offensive toys go, but the Chargers' quarterback will find a way to get it done.

 

DraftKings Running Backs - Week 4 DFS Picks

Le'Veon Bell (vs KC, $7,500)

The Pittsburgh Steelers are going to shove the ball down Le'Veon Bell's throat this week. Whether he likes it or not, he is going to touch the ball upwards of 30-40 times. At least, he should. The Kansas City Chiefs have not been great at stopping the run, and the Steelers' offense needs a little bit of stability after last week's terrible loss to the Philadelphia Eagles. Bell has yet to play this season, but everyone knows that he is the best running back in the league. He has something to prove tonight, and that is exactly what he will do. Pay up for his high price tag. There are plenty of value plays to make it work.

Carlos Hyde (vs DAL, $4,200)

Even with Le'Veon Bell back in action this week, Carlos Hyde is the most valuable running back on the board. He gets a solid matchup against the Dallas Cowboys, a team that struggles defensively, and he has been great all season so far. In two of his first three games, he has over 20 fantasy points. Finding the end zone four times, Hyde is a high-upside, low-priced fantasy steal this week. He is part of Chip Kelly's fast-paced offense now, and it looks like he is going to excel. There is no reason to avoid him. Roster him in both 50/50 and touranment lineups without hesitation.

 

DraftKings Wide Receivers - Week 4 DFS Picks

Tyrell Williams (vs NO, $4,400)

It is always a great idea to pair a wide receiver with a quarterback in daily fantasy football. It increases the upside of the lineup. Even before Keenan Allen went down with an injury, Williams was targeted five times. That was week one. In week three, he was targeted nine times, and he is quickly becoming a bigger part of the San Diego Chargers' offense. He is going to start finding the end zone more frequently, as long as his targets stay up. In his last two starts, he has 12.9 and 15.1 fantasy points, making him a great play in both 50/50 contests and tournaments. He is very likely to hit value.

Quincy Enunwa (vs SEA, $4,400)

Quincy Enunwa is having a great season so far, as far as fantasy is concerned. With 25 targets in three weeks, he is averaging over 13 fantasy points per game. For his price tag, that is solid. Eric Decker is out this week with a partially torn rotator cuff, so Enunwa is going to continue to see more targets. In week three, he had 11, which was one more than Brandon Marshall. Marshall is going to get shadowed and likely double-covered by the Seattle Seahawks' best members of the secondary, leaving Enunwa room to work. As long as he makes the most of his targets, Enunwa will at least hit value.

 

DraftKings Tight Ends - Week 4 DFS Picks

Zach Miller (vs DET, $2,700)

This is the easiest recommendation of the week. Zach Miller is entirely too cheap on DraftKings right now. He gets a great matchup against the Detroit Lions, and the Chicago Bears have to start Brian Hoyer with Jay Cutler currently dealing with an injury. Hoyer loves to check down to the tight end, evidenced by his nine targets, eight receptions, and two touchdowns last week against the Dallas Cowboys. He posted over 25 fantasy points. His price tag last week was higher than his price tag this week. Miller is poised to have a great season, especially if Cutler remains injured. He will save quite a bit of salary cap space, as well. Use him in both 50/50 contests and tournaments.

 




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REAL-TIME FANTASY NEWS

Brandon Montour

Hurt on Tuesday
Sam Merrill

Remains on Shelf Wednesday
Max Strus

Still Out Wednesday
Ayo Dosunmu

May Miss Another Game Wednesday
Brandon Clarke

Upgraded to Questionable on Injury Report
Cam Spencer

Unavailable Wednesday
Mike Conley

Remains Sidelined Wednesday
Zach LaVine

to Be Re-Evaluated in One Week
Mike Trout

Angels Open to Mike Trout Playing Center Field in 2026
Victor Wembanyama

Coming off the Bench on Tuesday Night
Rudy Gobert

Not on the Injury Report for Wednesday
Anthony Edwards

on the Injury Report Again for Wednesday Night
Ja Morant

Questionable for Wednesday's Meeting With Timberwolves
Saquon Barkley

Misses Practice With Stinger
RJ Harvey

Dealing With Rib Injury
Josh Jacobs

Intends to Play Against Bears on Saturday
Zach Bogosian

Misses Tuesday's Game
Marcus Johansson

Unavailable Tuesday
Artyom Levshunov

Scratched for Tuesday
Mathew Barzal

a Game-Time Call Tuesday
Joseph Woll

Returns to Action Tuesday
Mike Matheson

Won't Play on Tuesday
Rasmus Ristolainen

Makes Season Debut Tuesday
Bam Knight

Cardinals Place Bam Knight on Injured Reserve
CFB

Kansas State's Jayce Brown Intends to Transfer
CFB

Nation's Leading Passer Drew Mestemaker to Enter Transfer Portal
Justin Crawford

Phillies Planning to Start Justin Crawford in Center Field
CFB

Jayden Maiava Signs New Deal to Return to USC
CFB

Aidan Mizell Won't Return to Florida, Entering Transfer Portal
CFB

East Carolina Targeting Jordan Davis as Next Offensive Coordinator
Patrick Mahomes

Targeting Week 1 Return in 2026
Cutter Gauthier

Scores Twice at MSG
CFB

Michigan QB Jadyn Davis Set to Enter Transfer Portal
CFB

Travis Williams Joining Texas A&M Defensive Staff
Tim Stützle

Tim Stutzle Records Three Assists in Dramatic Win
Filip Forsberg

Nets 11th Career Hat Trick
Sam Reinhart

Pots Two Goals Against Lightning
Darcy Kuemper

Hurt Versus Stars
Gustav Forsling

Injured in Monday's Win
Brandon Hagel

Makes Early Exit Monday
Cooper Flagg

Becomes Youngest 40-Point Scorer in NBA History
Victor Wembanyama

May Come Off the Bench Again Tuesday
Nikola Jović

Nikola Jovic to Undergo MRI Tuesday
Sam Hauser

Tweaks Left Ankle Monday
Peyton Watson

Not Expected to Be Out Long-Term
Ja Morant

Injures Ankle in Monday's Win
Darren Waller

Hauls in Two Touchdowns in Monday Night Loss
Brandon Clarke

Still Out Monday
Rome Odunze

Considered Week-to-Week With Foot Injury
James Harden

Officially Active on Monday Night
Ja Morant

to Remain Under Minutes Restriction Monday
James Harden

a Game-Time Call Monday
Davante Adams

Considered Week-to-Week With Hamstring Injury
Jaylen Warren

to Play Through Illness on Monday Night
Will Smith

Sharks Place Will Smith on Injured Reserve
Andrei Vasilevskiy

Expected to Return Before Christmas
Dylan Holloway

to Miss Six Weeks
Patrick Kane

Expected to Miss at Least Two Games
Quinton Byfield

Ruled Out for Monday
Mika Zibanejad

Won't Play on Monday
Bhayshul Tuten

to Miss a Few Weeks With Finger Injury
Joe Burrow

Will Start the Rest of the Season
Jayden Daniels

to be Shut Down for Final Three Games
Philip Rivers

Will Start Again in Week 16
Drake London

Falcons "Very Hopeful" Drake London Can Return in Week 16
CFB

Dylan Raiola Entering His Name into Transfer Portal
Micah Parsons

MRI Confirms Torn ACL for Micah Parsons
CFB

Cincinnati's Brendan Sorsby Plans to Transfer When Portal Opens
Adolis García

Adolis Garcia, Phillies Finalizing One-Year Deal on Monday
Jaylen Warren

Questionable for Monday Night Due to Illness
Bam Knight

has "Bad Sprain," Unlikely to Play in Week 16
Brandon Royval

Suffers First-Round TKO Loss
CFB

Baylor, LSU, Miami Among Potential Suitors for DJ Lagway
CFB

Aidan Chiles Will Enter Transfer Portal
Manel Kape

Shines At UFC Vegas 112
New York Jets

Jets Fire Defensive Coordinator Steve Wilks
Kevin Vallejos

Gets Second-Round Knockout Win
Christian Watson

Avoids Long-Term Injury, Status for Week 16 Unclear
Giga Chikadze

Suffers His First Career Knockout Loss
CFB

Quarterback DJ Lagway Entering Transfer Portal
Cesar Almeida

Gets Dominated
Cezary Oleksiejczuk

Wins Sixth Fight In A Row
Teddye Buchanan

Ravens Linebacker Teddye Buchanan Believed to Have Torn ACL
Morgan Charrière

Morgan Charriere Suffers First-Round Knockout Loss
Melquizael Costa

Gets First-Round Knockout Win
Marcus Buchecha

Still Winless In The UFC
Kennedy Nzechukwu

And Marcus Buchecha Fight To Draw
Lance Gibson jr

Lance Gibson Jr. Drops Decision In His UFC Debut
King Green

Gets Back In The Win Column
Dallas Goedert

has Third Two-Touchdown Game on Sunday
Kenley Jansen

Agrees to One-Year Deal With Tigers
Merrill Kelly

Returns to Diamondbacks on Two-Year Deal
Jorge Polanco

Agrees to Two-Year Deal With Mets
CFB

LaNorris Sellers to Return to South Carolina in 2026
CFB

Washington State Expected to Hire Kirby Moore as Next Head Coach
CFB

Kyle Whittingham Stepping Down as Utah Head Coach
Manel Kape

Set For UFC Vegas 112 Main Event
Brandon Royval

An Underdog At UFC Vegas 112
Kevin Vallejos

Set For His Third UFC Fight
Giga Chikadze

In Dire Need Of Victory
Cesar Almeida

Set To Welcome Cezary Oleksiejczuk To The UFC
Cezary Oleksiejczuk

Set To Make His UFC Debut
Maikel Garcia

Royals Agree on Five-Year Extension
Melquizael Costa

Looks To Extend His Win Streak
Morgan Charrière

Morgan Charriere Looks to Win Second Consecutive Fights
Marcus Buchecha

Looks To Bounce Back
CFB

Sherrone Moore Charged with Home Invasion, Among Other Charges
CFB

Freddie Kitchens Fired from North Carolina Coaching Staff
CFB

Bryce Underwood Could Leave Michigan Without Buyout
Fernando Tatis Jr.

Padres Not Considering Trading Fernando Tatis Jr.
Tarik Skubal

Tigers Engaged in "Serious Talks" Around Trading Tarik Skubal at the Winter Meetings
CFB

Chris Brazzell II Declaring for NFL Draft
CFB

Fernando Mendoza Named AP College Football Player of the Year
Raisel Iglesias

to Remain the Braves Closer
Robert Suarez

Agrees on Three-Year Deal With Braves
CFB

Sherrone Moore Remains in Police Custody

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