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DraftKings Daily Fantasy Baseball Picks (9/26/19): MLB DFS Lineups

The final Thursday is a weird day with a split-slate actually favoring the early slate in terms of the number of games. However, the focus for us here will be on the late slate, where we will be hoping for some entertainment despite not many playoff scenarios in play on the slate.

The Mets, Astros and the Athletics are the favorites on this slate by some distance, with all three having a line better than -200. The Indians are also dead on -200 and the Cubs are -177 so we have reasonably big favorites at this stage. Strangely we do not have a single game on this slate with a total of 10 or above. Four of the five games sit between 9-and-9.5 with the Mets and Marlins sitting in the region of 7.5 runs.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 9/26/19. The lineup picks will range from some of the elite players to mid-priced options and value plays. Be sure to also check out all the Vegas Odds for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @benrolfe15.

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DraftKings DFS Starting Pitchers

Sean Manaea, OAK (@ SEA) - $10,400

Here are the returns from Manaea so far since his return from injury; 18.9, 35.4, 26.5, 16.0. Those are some nice returns for both fantasy players and the Athletics, and this start could be up there among the best. The Mariners were nearly no-hit for the third time in a season last night by Zack Greinke and they were shutout for the second straight game. This offense that was at one point feared by opposition pitchers is going out with a whimper, and against a pitcher in the form of Manaea, this could be a really impressive day.

Aaron Civale, CLE (@ CWS) - $9,600 

If you can get Civale in your roster today then I would. The pitching options outside of Jose Quintana do not excite and Civale has offered decent floor and upside. Today he faces the White Sox, who have been hit or miss offensively in conditions which should benefit pitching. The only downside here is that Civale is unlikely to get you a massive three-times ROI, so if you want to take a gamble on someone like Felix Hernandez in GPP that is definitely in play.

 

DraftKings DFS Infielders

C - Roberto Perez, CLE (@ CWS) - $3,600

While the weather has a lean to the pitchers and Dylan Cease has been better recently there is still reason to chase a couple of Indians hitters in this one. Against left-handed pitchers, Roberto Perez has been solid, with a .266 batting average, nine home runs, .242 ISO and a .363 wOBA.

1B - Albert Pujols, LAA (vs. HOU) - $4,000 

Wade Miley has been struggling a lot recently and the Angels could take advantage of this today. When facing left-handed pitchers Pujols has 11 of his 23 home runs with a .262 batting average, .256 ISO and a .340 wOBA.

2B - Jose Altuve, HOU (@ LAA) - $4,800 

This was a tough position to pick today as no one really stood out. Therefore, I went with Mr. Trustworthy who has five home runs in September, with 20 and a .325 batting average in the second half. He has been worse against right-handed pitchers but he still has a .288 batting average, .219 ISO and a .326 wOBA.

3B - Matt Chapman, OAK (@ SEA) - $4,100

I just have this feeling we might see a Felix Hernandez special today in Seattle in what could be his last ever game as a Mariner. However, Chapman has a .253 batting average, 24 home runs, .352 wOBA, and a .246 ISO.

SS - Francisco Lindor, CLE (@ CWS) - $4,600

Another tough position today so I have gone for someone I just trust in the form of Lindor. Against right-handed pitchers, he has a .298 batting average, 23 home runs, .359 wOBA, and .258 ISO this season.

 

DraftKings DFS Outfielders

Michael Conforto, NYM (vs. MIA) - $4,600

The Mets season is all but done but you can bet they will want to finish with a bang tonight in their final home game of the season. Conforto has 17 home runs and a .275 batting average in the second half, as well as a .265 batting average, with a .287 ISO, and a .384 wOBA against right-handed pitchers this season.

Kole Calhoun, LAA (vs. HOU) - $4,300

Power is one thing you see regularly from Calhoun and he has a .215 ISO this season against left-handed pitchers. His numbers are not great but this is a pick against Wade Miley as much as anything.

Jason Heyward, CHC (@ PIT) - $3,900

There is not a lot to be excited about with Heyward, but he can offer a solid value play, especially against right-handed pitchers. This season, 19 of his 21 home runs have come off of right-handed pitchers, with 13-of-21 coming on the road. Against right-handed pitchers, he has a .202 ISO and a .350 wOBA this season.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

MLB

Orioles-Tigers Game Postponed on Saturday
RJ Harvey

to be Relegated to Third-Down Role After Rookie RB Addition?
Baker Mayfield

A Lot of Uncertainty Surrounding Baker Mayfield Going into Fourth Year in Tampa
Brian Robinson Jr.

a Must-Have Handcuff in Dynasty Leagues?
Sam LaPorta

Could be Excellent Buy-Low Candidate for Risk-Tolerant Managers
Jordyn Tyson

on a "Maintenance Plan" During Offseason Workouts
Kenneth Walker III

One of Dynasty's Biggest Risers for 2026
D'Andre Swift

an Underappreciated Dynasty Buy Candidate
Ray Davis

Still a Dynasty Stash Despite a Lack of Standalone Value
Travis Kelce

Now a Low-Cost Dynasty Rental
DJ Moore

a Reasonable Buy Candidate Now That Dynasty Market Has Cooled
MLB

Rays-Yankees Postponed on Saturday
Devin Vassell

Posts 20 Points in Game 3 Loss
De'Aaron Fox

Struggles From Deep in Friday's Loss
Victor Wembanyama

Held to Four Rebounds in Game 3 Loss
Jaylin Williams

Catches Fire From Deep Friday
Jared McCain

Drops Playoff-High 24 Points in Game 3
Nazem Kadri

Contributes an Assist in Losing Effort
Shai Gilgeous-Alexander

Guides Thunder to 2-1 Series Lead
Ajay Mitchell

Does Not Return in Game 3 Win
Ross Colton

Nets Lone Avalanche Goal Friday Night
Rasmus Andersson

Extends Assist Streak to Four Games
Pavel Dorofeyev

Focuses on Playmaking in Friday's Win
Jack Eichel

Enjoys Multi-Point Outing in Game 2 Win Friday
Ivan Barbashev

Amasses Three Points as Golden Knights Grab 2-0 Series Lead
Jordan James

Most Likely to be 49ers' RB2 in 2026
Mickey Moniak

Heads to Injured List With Ankle Sprain
Rudy Gobert

Earns Eighth All-Defensive First-Team Selection
Victor Wembanyama

Headlines 2025-26 All-Defensive First Team
Ajay Mitchell

Starting Game 3 Against Spurs
Dylan Harper

Available for Game 3 Against Thunder
De'Aaron Fox

Returns to Action Friday
Jalen Williams

Won't Play Friday Night
Derrick Henry

Remains in RB1 Discussion
Ladd McConkey

is Solid Buy-Low Candidate
Ryan Flournoy

an Intriguing Dynasty Stash Option
Jalen Nailor

is Expected to Have Larger Role in Las Vegas
Frederik Andersen

Hurricanes Keep Faith in Frederik Andersen
Devon Levi

Attracting Interest From Senators
Jacoby Brissett

Cardinals Not Close to a Reworked Deal
Scott Wedgewood

Starting Game 2 Against Golden Knights
Ben Hutton

Scratched for Game 2 Against Avalanche
Mark Stone

Won't Play Friday
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
Cale Makar

Remains Out Friday
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
NFL

Evan Stewart Pushing Oregon Receiving Corps
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
New York Giants

Giants, GM Joe Schoen Agree on a Multi-Year Extension
Andrew Thomas

Giants Managing Multiple Injuries for Andrew Thomas
Cam Ward

Loses 10 Pounds in the Offseason
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Tucker Kraft

a Top Trade Target in Dynasty Leagues?
Evan Mobley

Fills the Box Score in Game 2 Loss
James Harden

Held to Two Assists Thursday
Donovan Mitchell

Leads Cavaliers in Scoring in Game 2 Defeat
Karl-Anthony Towns

Records Double-Double in Game 2 Win
Sebastian Aho

Picks Up an Assist in Series-Opening Loss
Mikal Bridges

Adds 19 Points as Knicks Grab 2-0 Lead
Jalen Brunson

Hands Out 14 Assists in Game 2 Win
Seth Jarvis

Needs 33 Seconds to Score in Game 1 Loss
Josh Hart

Erupts for Playoff Career-High 26 Points in Game 2
Jaccob Slavin

Struggles in Game 1 Against Canadiens
Jakub Dobes

Sharp in Game 1 Victory
Cole Caufield

Bags Two Points in Impressive Road Win
Juraj Slafkovsky

Opens Conference Finals With Three-Point Performance
Nick Suzuki

Notches Three Assists in Game 1 Win Over Hurricanes
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Jrue Holiday

Wants to Stay in Portland
Alex Tuch

Hopes to Remain in Buffalo
Sidney Crosby

Wants to Play for "as Many Years as Possible"
Robby Snelling

Will Undergo Tommy John Surgery
Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
CFB

Lincoln Riley Believes USC is Ready for Playoff Run
CFB

Notre Dame-Stanford Rivalry Renewed Through 2028
CFB

Ahmad Hardy Says He's "Back to the Road to Success"
CFB

Texas Tech Graduate Judge Recuses Himself from Brendan Sorsby Case
CFB

UCLA Tackle Jordan Davis Officially Eligible for 2026 Season
CFB

Bret Bielema Supports Significant College Football Playoff Expansion
Michael Thorbjornsen

Brings High Upside to CJ Cup Byron Nelson
Luke List

Carrying Poor Form Into CJ Cup Byron Nelson
Tom Kim

Hoping to Build on Strong Myrtle Beach Finish
PGA

Sungjae Im Brings Upside to TPC Craig Ranch
Billy Horschel

Looking for Turnaround at CJ Cup Byron Nelson
Adam Hadwin

Difficult to Trust at TPC Craig Ranch
Tony Finau

Looking for Consistency at TPC Craig Ranch
Luke Clanton

Searching for Form at CJ Cup Byron Nelson
Aaron Rai

Withdraws From CJ Cup Byron Nelson
Wyndham Clark

Can Wyndham Clark Find Form at CJ Cup?
Si Woo Kim

Looks To Stay Hot at CJ Cup
Scottie Scheffler

to Defend CJ Cup Byron Nelson Title This Week
Jordan Spieth

Looking For Victory at TPC Craig Ranch
PGA

Matti Schmid Looks to Keep Recent Momentum Going at TPC Craig Ranch
Brooks Koepka

a High-Upside Play at CJ Cup Byron Nelson
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Gerrit Cole

to Make Season Debut on Friday Against Rays
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
CFB

Kemario Taylor a Breakout Candidate at Quarterback
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Corey Seager

Going on Injured List With Back Injury
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF