X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


DraftKings Daily Fantasy Baseball Picks (9/21/19): MLB DFS Lineups

Saturday brings us a full 15-game slate. Six of those games fall in the early part of the slate with the other nine making up the main featured slate for the day.

The featured slate brings us four monster favorites in the form of the Astros, Twins, Athletics and Dodgers, with all of them better than -300. We also have two teams with odds better than -200 in the Brewers and Braves, so there are plenty of pitching options to choose from. The biggest expected run totals on this slate can be found in Baltimore, Cleveland and Minnesota, but with plenty of pitching mismatches on the slate there are many opportunities outside of those three games.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 9/21/19. The lineup picks will range from some of the elite players to mid-priced options and value plays. Be sure to also check out all the Vegas Odds for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @benrolfe15.

Featured Promo! Save 50% on any PGA Premium Pass using discount code MASTERS, this week only! Win more with our DFS and Betting Packages, get expert tools and advice from proven winners including the Lineup Optimizer, Research Station, betting/props cheat sheet and more. GAIN FULL ACCESS HERE

 

DraftKings DFS Starting Pitchers

Sean Manaea, OAK (vs. TEX) - $9,800

Manaea’s return from the disabled list could not really have gone much better. Three starts, 18 innings and just one earned run allowed with 21 strikeouts. Now he is facing a Rangers team with just three earned runs in their current three-game road trip. This should be both a nice floor and ceiling play on today’s slate.

Wade Miley, HOU (vs. LAA) - $5,700 

Miley is not far away from a rough stretch in which he allowed 12 earned runs for just one out across two starts. However, he bounced back last time out with a four-strikeout, two earned run, six innings outing at the Royals last time out. The Angels have all but given up on the season and Miley should be able to take advantage.

 

DraftKings DFS Infielders

C - Roberto Perez, CLE (vs. PHI) - $3,700

A solid, if unimpressive, season for Perez has at been headlines by his numbers against left-handed pitchers. This season he has a .252 batting average, .228 ISO and a .347 wOBA with lefties on the mound.

1B - Daniel Vogelbach, SEA (@ BAL) - $4,000 

It has been a nice season for Vogelbach against right-handed pitchers with 25 of his 30 home runs coming off them. His numbers against righties this season stand as a .231 batting average, .271 ISO, and .364 wOBA.

2B - Max Muncy, LAD (vs. COL) - $4,400 

Muncy’s numbers against righties are not spectacular but against Chi-Chi Gonzalez we aren’t looking for spectacular. Muncy has 22 home runs, a .256 ISO and a .362 wOBA.

3B - Josh Donaldson, ATL (vs. SF) - $4,100

Donaldson has nice numbers against righties this year. So far he has a .267 batting average, a .274 ISO and a .379 wOBA. He also has a whopping .332 ISO and .429 wOBA this season.

SS - Corey Seager, LAD (vs. COL) - $4,100

Seager is another hitter with solid numbers against right-handed pitchers. The young shortstop has a .285 batting average, .226 ISO and a .354 wOBA when righties are on the mound this year.

 

DraftKings DFS Outfielders

Mark Canha, OAK (vs. TEX) - $4,200

Canha’s value against lefties is due to his ability to get the ball out of the park. He has eight home runs against lefties this year, giving him a .248 ISO. He has also been good at clearing the fences at home, with a .276 ISO.

Joc Pederson, LAD (vs. COL) - $4,100

September has been good to Pederson. He has six home runs and an impressive .375 batting average so far this month. All 32 of his home runs this year have come when facing right-handed hitters, and 24 of them have come at home. He has a .304 ISO against righties and a .386 ISO as home this season.

Jake Marisnick, HOU (vs. LAA) - $3,500

Marisnick is a hitter I have used a few times this year against lefties because of his price. He has a .204 ISO against lefties and is part of one of the best lineups in the majors so for this price it is worth the gamble.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Jordan James

Most Likely to be 49ers' RB2 in 2026
Mickey Moniak

Heads to Injured List With Ankle Sprain
Rudy Gobert

Earns Eighth All-Defensive First-Team Selection
Victor Wembanyama

Headlines 2025-26 All-Defensive First Team
Ajay Mitchell

Starting Game 3 Against Spurs
Dylan Harper

Available for Game 3 Against Thunder
De'Aaron Fox

Returns to Action Friday
Jalen Williams

Won't Play Friday Night
Derrick Henry

Remains in RB1 Discussion
Ladd McConkey

is Solid Buy-Low Candidate
Ryan Flournoy

an Intriguing Dynasty Stash Option
Jalen Nailor

is Expected to Have Larger Role in Las Vegas
Frederik Andersen

Hurricanes Keep Faith in Frederik Andersen
Devon Levi

Attracting Interest From Senators
Jacoby Brissett

Cardinals Not Close to a Reworked Deal
Scott Wedgewood

Starting Game 2 Against Golden Knights
Ben Hutton

Scratched for Game 2 Against Avalanche
Mark Stone

Won't Play Friday
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
Cale Makar

Remains Out Friday
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
NFL

Evan Stewart Pushing Oregon Receiving Corps
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
New York Giants

Giants, GM Joe Schoen Agree on a Multi-Year Extension
Andrew Thomas

Giants Managing Multiple Injuries for Andrew Thomas
Cam Ward

Loses 10 Pounds in the Offseason
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Tucker Kraft

a Top Trade Target in Dynasty Leagues?
Cedric Tillman

Falling Out of Favor in Cleveland
Emmett Johnson

the Handcuff to Roster in Kansas City?
Devaughn Vele

Could Dynasty Managers Sell High on Devaughn Vele Early in the Season?
Brenen Thompson

a Perfect Fit for Chargers, Rising in Dynasty Leagues?
Jonathan Taylor

Is Jonathan Taylor Still a High-End Dynasty Option?
Malik Nabers

' Recovery Timeline Still Unclear
Jaxon Smith-Njigba

Comfortably Into His Dynasty Prime
Saquon Barkley

Still a Capable League-Winner at a Sunken Dynasty Cost
Jack Campbell

Signs Four-Year Extension with Lions
Matthew Stafford

Signs One-Year Extension with Rams
Evan Mobley

Fills the Box Score in Game 2 Loss
James Harden

Held to Two Assists Thursday
Donovan Mitchell

Leads Cavaliers in Scoring in Game 2 Defeat
Karl-Anthony Towns

Records Double-Double in Game 2 Win
Sebastian Aho

Picks Up an Assist in Series-Opening Loss
Mikal Bridges

Adds 19 Points as Knicks Grab 2-0 Lead
Jalen Brunson

Hands Out 14 Assists in Game 2 Win
Seth Jarvis

Needs 33 Seconds to Score in Game 1 Loss
Josh Hart

Erupts for Playoff Career-High 26 Points in Game 2
Jaccob Slavin

Struggles in Game 1 Against Canadiens
Jakub Dobes

Sharp in Game 1 Victory
Cole Caufield

Bags Two Points in Impressive Road Win
Juraj Slafkovsky

Opens Conference Finals With Three-Point Performance
Nick Suzuki

Notches Three Assists in Game 1 Win Over Hurricanes
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Jrue Holiday

Wants to Stay in Portland
Ayo Dosunmu

Timberwolves Hope to Bring Back Ayo Dosunmu
Dylan Harper

Considered Questionable for Friday Night
De'Aaron Fox

Listed as Questionable for Game 3
Jalen Williams

Questionable for Game 3 Against Spurs
Alex Tuch

Hopes to Remain in Buffalo
Sidney Crosby

Wants to Play for "as Many Years as Possible"
Troy Terry

Could Miss Start of Next Season Due to Hip Surgery
Arber Xhekaj

Scratched for Game 1 of Eastern Conference Finals
Jakub Dobes

Seeks More Success Against Hurricanes
Frederik Andersen

Looks to Stay Undefeated Thursday
Robby Snelling

Will Undergo Tommy John Surgery
Devin Vassell

Contributes 22 Points in Wednesday's Loss
Stephon Castle

Tallies Team-High 25 Points in Game 2 Loss
Victor Wembanyama

Records Eighth Postseason Double-Double
Valeri Nichushkin

Ends Scoring Slump in Game 1 Loss
Nathan MacKinnon

Extends Point Streak With an Assist
Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
CFB

Lincoln Riley Believes USC is Ready for Playoff Run
CFB

Notre Dame-Stanford Rivalry Renewed Through 2028
CFB

Ahmad Hardy Says He's "Back to the Road to Success"
CFB

Texas Tech Graduate Judge Recuses Himself from Brendan Sorsby Case
CFB

UCLA Tackle Jordan Davis Officially Eligible for 2026 Season
CFB

Bret Bielema Supports Significant College Football Playoff Expansion
Michael Thorbjornsen

Brings High Upside to CJ Cup Byron Nelson
Luke List

Carrying Poor Form Into CJ Cup Byron Nelson
Tom Kim

Hoping to Build on Strong Myrtle Beach Finish
PGA

Sungjae Im Brings Upside to TPC Craig Ranch
Billy Horschel

Looking for Turnaround at CJ Cup Byron Nelson
Adam Hadwin

Difficult to Trust at TPC Craig Ranch
Tony Finau

Looking for Consistency at TPC Craig Ranch
Luke Clanton

Searching for Form at CJ Cup Byron Nelson
Aaron Rai

Withdraws From CJ Cup Byron Nelson
Wyndham Clark

Can Wyndham Clark Find Form at CJ Cup?
Si Woo Kim

Looks To Stay Hot at CJ Cup
Scottie Scheffler

to Defend CJ Cup Byron Nelson Title This Week
Jordan Spieth

Looking For Victory at TPC Craig Ranch
PGA

Matti Schmid Looks to Keep Recent Momentum Going at TPC Craig Ranch
Brooks Koepka

a High-Upside Play at CJ Cup Byron Nelson
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Gerrit Cole

to Make Season Debut on Friday Against Rays
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
CFB

Kemario Taylor a Breakout Candidate at Quarterback
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Corey Seager

Going on Injured List With Back Injury
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF