X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

DraftKings Daily Fantasy Baseball Picks (9/21/19): MLB DFS Lineups

Saturday brings us a full 15-game slate. Six of those games fall in the early part of the slate with the other nine making up the main featured slate for the day.

The featured slate brings us four monster favorites in the form of the Astros, Twins, Athletics and Dodgers, with all of them better than -300. We also have two teams with odds better than -200 in the Brewers and Braves, so there are plenty of pitching options to choose from. The biggest expected run totals on this slate can be found in Baltimore, Cleveland and Minnesota, but with plenty of pitching mismatches on the slate there are many opportunities outside of those three games.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 9/21/19. The lineup picks will range from some of the elite players to mid-priced options and value plays. Be sure to also check out all the Vegas Odds for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @benrolfe15.

Featured Promo! Save 30% on any Premium Pass using discount code NEW. Win more with our DFS, Betting and Season-Long Pass, get expert tools and advice from proven winners! GAIN ACCESS

 

DraftKings DFS Starting Pitchers

Sean Manaea, OAK (vs. TEX) - $9,800

Manaea’s return from the disabled list could not really have gone much better. Three starts, 18 innings and just one earned run allowed with 21 strikeouts. Now he is facing a Rangers team with just three earned runs in their current three-game road trip. This should be both a nice floor and ceiling play on today’s slate.

Wade Miley, HOU (vs. LAA) - $5,700 

Miley is not far away from a rough stretch in which he allowed 12 earned runs for just one out across two starts. However, he bounced back last time out with a four-strikeout, two earned run, six innings outing at the Royals last time out. The Angels have all but given up on the season and Miley should be able to take advantage.

 

DraftKings DFS Infielders

C - Roberto Perez, CLE (vs. PHI) - $3,700

A solid, if unimpressive, season for Perez has at been headlines by his numbers against left-handed pitchers. This season he has a .252 batting average, .228 ISO and a .347 wOBA with lefties on the mound.

1B - Daniel Vogelbach, SEA (@ BAL) - $4,000 

It has been a nice season for Vogelbach against right-handed pitchers with 25 of his 30 home runs coming off them. His numbers against righties this season stand as a .231 batting average, .271 ISO, and .364 wOBA.

2B - Max Muncy, LAD (vs. COL) - $4,400 

Muncy’s numbers against righties are not spectacular but against Chi-Chi Gonzalez we aren’t looking for spectacular. Muncy has 22 home runs, a .256 ISO and a .362 wOBA.

3B - Josh Donaldson, ATL (vs. SF) - $4,100

Donaldson has nice numbers against righties this year. So far he has a .267 batting average, a .274 ISO and a .379 wOBA. He also has a whopping .332 ISO and .429 wOBA this season.

SS - Corey Seager, LAD (vs. COL) - $4,100

Seager is another hitter with solid numbers against right-handed pitchers. The young shortstop has a .285 batting average, .226 ISO and a .354 wOBA when righties are on the mound this year.

 

DraftKings DFS Outfielders

Mark Canha, OAK (vs. TEX) - $4,200

Canha’s value against lefties is due to his ability to get the ball out of the park. He has eight home runs against lefties this year, giving him a .248 ISO. He has also been good at clearing the fences at home, with a .276 ISO.

Joc Pederson, LAD (vs. COL) - $4,100

September has been good to Pederson. He has six home runs and an impressive .375 batting average so far this month. All 32 of his home runs this year have come when facing right-handed hitters, and 24 of them have come at home. He has a .304 ISO against righties and a .386 ISO as home this season.

Jake Marisnick, HOU (vs. LAA) - $3,500

Marisnick is a hitter I have used a few times this year against lefties because of his price. He has a .204 ISO against lefties and is part of one of the best lineups in the majors so for this price it is worth the gamble.

MLB DFS News and Injury Alerts




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Chase Elliott

Is Chase Elliott Worth Rostering At Daytona This Week For DFS?
Austin Cindric

May Be Worth Rostering At Daytona
NFL

Browns to Spend Top Draft Picks on Receiver or Offensive Lineman?
Brad Keselowski

Is Brad Keselowski Worth Rostering for Daytona Lineups?
Tyler Reddick

May be A Solid and Sneaky Pick for Daytona Lineups
Alex Bowman

is A Highly Favorable Mid-Tier Option for Daytona
Ross Chastain

Could be A Top DFS Scorer for Daytona
Justin Allgaier

is One of the Safest DFS Options for Daytona
Daulton Varsho

Coming Off Career-Best Showing at the Plate
Tim Stützle

Tim Stutzle Matches Team Germany Record With Third Goal
Karl-Anthony Towns

Jalen Brunson, Karl-Anthony Towns Claim 2026 Shooting Stars Crown
Jack Eichel

Off to Hot Start in Olympics
Keshad Johnson

Wins 2026 Slam Dunk Contest
NHL

Mads Sogaard Injured Saturday
Bryan Reynolds

Poised for a Bounce-Back Season?
Ramón Laureano

Ramon Laureano Coming Off Terrific Season at the Dish
Damian Lillard

Wins Third 3-Point Contest Title
Pablo López

Health the Biggest Key to Success for Pablo Lopez in 2026?
Tatsuya Imai

Brings Incredible Track Record to Houston
Phoenix Suns

Haywood Highsmith Agrees to Multiyear Deal with Suns
Trevor Rogers

to Repeat Dominant Season?
Luka Dončić

Luka Doncic Returns For All-Star Game On Minutes Cap
NASCAR

Christoper Bell Emerging As One of The Best at Daytona
William Byron

Trying for Third Straight Daytona 500 Victory
Kyle Larson

Has Never Posted a Top-Five Finish at Daytona
Denny Hamlin

Is Denny Hamlin Overrated at Daytona?
Chris Buescher

an Easy DFS Pick for the Daytona 500
Kyle Busch

on Pole, Still Searching for Elusive Daytona 500 Victory
Jimmie Johnson

Still Has More Left in The Tank
Giannis Antetokounmpo

Feeling "100 Percent"
Kris Bubic

Throws Batting Practice Session on Saturday
Jackson Kowar

Orioles Acquire Jackson Kowar from Twins
Cionel Pérez

Nationals Sign Cionel Perez to Minor-League Deal
Germán Márquez

German Marquez Signs Deal with Padres
Grayson Rodriguez

is Aiming to Make 30 Starts
Lucas Raymond

Ties Team Sweden Record With Three Points Saturday
Anton Lundell

Battling Illness
Kevin Fiala

Out for Season
Merrill Kelly

to Start on Opening Day for Arizona
Jac Caglianone

to Have "Plenty of Opportunities to Play" in 2026
Jordan Lawlar

Could Earn Everyday Playing Time Early in 2026
Maikel Garcia

Poised to Build on 2025 Breakout?
Nick Pivetta

a Regression Candidate Following Career-Year in 2025?
Brusdar Graterol

Opening Day Availability in Question
Spencer Jones

"Currently Blocked" from Playing Time with the Yankees
Jace Jung

Taking Reps at First Base
Jasson Domínguez

Yankees Want Everyday Reps for Jasson Dominguez
Shota Imanaga

Adjusting his Pitch Repertoire
Riley Minix

Signs Two-Way Deal With Cavaliers
Luka Dončić

Luka Doncic Likely Available for All-Star Game
Toronto Raptors

Chris Paul Retires From Basketball
Zach LaVine

to Undergo Season-Ending Hand Surgery
David Pastrnak

Gets Off the Mark at Olympics
Macklin Celebrini

Pots Another Goal Friday
Kevin Fiala

Stretchered Off Against Canada
Aaron Rodgers

Likely to Return to Steelers?
Terry McLaurin

Commanders Want Terry McLaurin to Get 10 Targets a Game
Deandre Ayton

Remains Day-to-Day for Lakers
LeBron James

Posts Historic Triple-Double in Win
Ja Morant

Still Without Clear Return Date
Luka Dončić

Luka Doncic Expected Back After All-Star Break
Oscar Tshiebwe

Enters Concussion Protocol Thursday
Naji Marshall

Exits Early with Foot Strain
Daniel Gafford

Leaves Game with Ankle Issue
Jordan Binnington

Records 26-Save Shutout Against Czechia
Connor McDavid

Ties Canadian Record With Three Assists in Olympic Debut
Josh Morrissey

Hurt in Olympic Opener
Robert Williams III

Will Not Play Against Utah
Deni Avdija

Sidelined vs. Jazz
Alexandre Sarr

to Miss Multiple Weeks
Naji Marshall

Gets Upgraded to Probable
CFB

Trinidad Chambliss Eligible for 2026 Season
CFB

BYU's Parker Kingston Charged with Felony Rape
Cameron Young

Looking for Pebble Beach Success
J.J. Spaun

Looks to Turn Things Around at Pebble Beach
Collin Morikawa

Eyes Turnaround at Pebble Beach
Jake Knapp

Brings Hot Form to Pebble Beach
Nick Taylor

in Good Form Going into Pebble Beach Event
Viktor Hovland

Carrying Momentum Into Pebble Beach
Tommy Fleetwood

Set for 2026 PGA Tour Debut at Pebble Beach
Harris English

Looks to Build on Steady Form at Pebble Beach
Justin Rose

Tuned in for AT&T Pebble Beach Pro-Am
Keegan Bradley

a Boom-or-Bust Play at Pebble Beach
Maverick McNealy

Playing Well with Pebble Beach Looming
Russell Henley

Carries Momentum to Pebble Beach
Shane Lowry

Makes 2026 PGA Tour Debut at Pebble Beach
Michael Kim

Putting Well with Pebble Beach on the Horizon
Billy Horschel

a Little Rattled After Consecutive Missed Cuts
Ben Griffin

Solid But Not Spectacular Early in 2026
Wyndham Clark

Has Question Marks Heading to Pebble Beach
Daniel Berger

Heating Up at the Right Time for Pebble Beach
Jordan Spieth

Looking For a Return to Form at Pebble Beach
Juuse Saros

Starting Wednesday
William Nylander

Iffy for Olympic Opener
Martin Necas

Ready for Thursday
Drake Maye

Says his Shoulder Injury was Significant
Xander Schauffele

Trying to Get the Motor Going at Pebble Beach
Hideki Matsuyama

Trying to Overcome Sunday Collapse
Kenneth Walker III

Runs Away With Super Bowl MVP Honors
Vinicius Oliveira

Suffers His First UFC Loss
Mario Bautista

Gets Back In The Win Column
Kyoji Horiguchi

Dominates At UFC Vegas 113
Amir Albazi

Gets Dominated At UFC Vegas 113
Rizvan Kuniev

Earns His First UFC Win
Jailton Almeida

Drops Decision At UFC Vegas 113
Marc-Andre Barriault

Loses Back-To-Back Fights
Michal Oleksiejczuk

Gets His Third Win In A Row
Las Vegas Raiders

Klint Kubiak Confirms he Will be Next Raiders Head Coach
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF