DraftKings Daily Fantasy Baseball Picks (9/21/19): MLB DFS Lineups

Saturday brings us a full 15-game slate. Six of those games fall in the early part of the slate with the other nine making up the main featured slate for the day.

The featured slate brings us four monster favorites in the form of the Astros, Twins, Athletics and Dodgers, with all of them better than -300. We also have two teams with odds better than -200 in the Brewers and Braves, so there are plenty of pitching options to choose from. The biggest expected run totals on this slate can be found in Baltimore, Cleveland and Minnesota, but with plenty of pitching mismatches on the slate there are many opportunities outside of those three games.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 9/21/19. The lineup picks will range from some of the elite players to mid-priced options and value plays. Be sure to also check out all the Vegas Odds for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @benrolfe15.

DraftKings DFS Starting Pitchers

Sean Manaea, OAK (vs. TEX) - $9,800

Manaea’s return from the disabled list could not really have gone much better. Three starts, 18 innings and just one earned run allowed with 21 strikeouts. Now he is facing a Rangers team with just three earned runs in their current three-game road trip. This should be both a nice floor and ceiling play on today’s slate.

Wade Miley, HOU (vs. LAA) - $5,700 

Miley is not far away from a rough stretch in which he allowed 12 earned runs for just one out across two starts. However, he bounced back last time out with a four-strikeout, two earned run, six innings outing at the Royals last time out. The Angels have all but given up on the season and Miley should be able to take advantage.

DraftKings DFS Infielders

C - Roberto Perez, CLE (vs. PHI) - $3,700

A solid, if unimpressive, season for Perez has at been headlines by his numbers against left-handed pitchers. This season he has a .252 batting average, .228 ISO and a .347 wOBA with lefties on the mound.

1B - Daniel Vogelbach, SEA (@ BAL) - $4,000 

It has been a nice season for Vogelbach against right-handed pitchers with 25 of his 30 home runs coming off them. His numbers against righties this season stand as a .231 batting average, .271 ISO, and .364 wOBA.

2B - Max Muncy, LAD (vs. COL) - $4,400 

Muncy’s numbers against righties are not spectacular but against Chi-Chi Gonzalez we aren’t looking for spectacular. Muncy has 22 home runs, a .256 ISO and a .362 wOBA.

3B - Josh Donaldson, ATL (vs. SF) - $4,100

Donaldson has nice numbers against righties this year. So far he has a .267 batting average, a .274 ISO and a .379 wOBA. He also has a whopping .332 ISO and .429 wOBA this season.

SS - Corey Seager, LAD (vs. COL) - $4,100

Seager is another hitter with solid numbers against right-handed pitchers. The young shortstop has a .285 batting average, .226 ISO and a .354 wOBA when righties are on the mound this year.

DraftKings DFS Outfielders

Mark Canha, OAK (vs. TEX) - $4,200

Canha’s value against lefties is due to his ability to get the ball out of the park. He has eight home runs against lefties this year, giving him a .248 ISO. He has also been good at clearing the fences at home, with a .276 ISO.

Joc Pederson, LAD (vs. COL) - $4,100

September has been good to Pederson. He has six home runs and an impressive .375 batting average so far this month. All 32 of his home runs this year have come when facing right-handed hitters, and 24 of them have come at home. He has a .304 ISO against righties and a .386 ISO as home this season.

Jake Marisnick, HOU (vs. LAA) - $3,500

Marisnick is a hitter I have used a few times this year against lefties because of his price. He has a .204 ISO against lefties and is part of one of the best lineups in the majors so for this price it is worth the gamble.

MLB DFS News and Injury Alerts