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DraftKings Daily Fantasy Baseball Picks (10/22/21): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on 10/22/21. Euan Leith's MLB DFS analysis and sleepers for building optimal DFS rosters.

Happy Friday, Rotoballers! The entire ALCS was flipped on its head within 24 hours as the Astros took games 4 and 5 to put themselves in the driver's seat for their third World Series appearance in the last five years. Still, Boston is more than capable of winning two straight, and I expect another back and forth contest between the last two American League teams. The NLCS is heading back to Atlanta, so we have a one-game Showdown contest on our hands for Friday night.

For DraftKings showdown contests, you'll pick one captain who costs 1.5 times his usual salary, but he also collects 1.5 times the number of points he scores in the game. Then, you'll fill in the five remaining utility slots with any player you want, as long as your roster has at least one player from each team. Starting pitching can be tricky in situations like this, but they also provide the safest route to fantasy points. That's the great thing about showdown games; you can build your roster anyway you choose.

This article will provide you with my daily fantasy baseball lineup picks for DraftKings on 10/22/2021. The lineup will range from some of the elite players to mid-priced options and value plays. You can also check out today's FanDuel MLB DFS lineup picks and read more DFS advice and lineup picks for other sports too. It's also important to monitor injury news and today's MLB starting lineups. If you have any questions or comments, find me on Twitter and ask away.

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DraftKings DFS Captain Options

Nathan Eovaldi ($15,800)

If Boston wants to claw their way back into this series, they will need their October talisman to come through with his best stuff. I'm interested in seeing where the roster percentage lands on Nathan Eovaldi because he has been the most consistent arm for the Red Sox in the postseason. Still, he had a disastrous, 24-pitch outing in relief just three days ago. If he comes in with a low roster rate, he could be a massive edge at captain.

In his first three starts in the playoffs, the right-handed hurler struck out 19 batters over 15 2/3 innings and made himself eligible for the win by pitching into the sixth inning all three times. Make sure to check in on Alex Cora's pre-game comments to see if he mentions anything about a pitch count for his Game 6 starter.

Yuli Gurriel ($10,800)

The 2021 AL batting champ is having himself quite a series in the ALCS. Yuli Gurriel has registered a hit in every game, with three games of the multi-hit variety. Over the five games so far, the Cuban is 9-for-19 (.473 batting average) with four runs, a double, a home run, six RBI, and two walks. And yet, he's still hitting seventh for this loaded Houston lineup. It usually wouldn't play, but there are so many good hitters ahead of El Pina, and it provides countless chances for fantasy points production.

Other Options: Luis Garcia ($15,300), Rafael Devers ($15,000), Yordan Alvarez ($12,900)

DraftKings DFS Utility Selections

Rafael Devers ($10,000)

Devers is one of the other options as a Captain pick, but he still needs to be written up as a utility option because he's having a fantastic ALCS. The Red Sox third baseman is 7-for-20 (.350 batting average) for the series with seven runs, three home runs, and six RBI while averaging 14.8 fantasy points per game. He's the Boston bat I trust the most right now, and I'll be doing my best to get him in my lineups.

Yordan Alvarez ($8,600)

The left-handed slugger erupted in Game 5 for a monster 28-point outing. Alvarez went 3-for-5 with two runs, a double, a home run, and three RBI. He has a hit in every game of this series, and it's usually a good bet to be hit hard and far when Alvarez makes contact with a ball. The Astros DH is one of the best candidates to hit a home run among the two rosters.

Michael Brantley ($6,200)

If you look up professional hitter in the dictionary, there is a picture of Michael Brantley next to the phrase. While that's the oldest cliche in the book (and announcers love to use it for Brantley), sometimes the shoe fits. The veteran lefty bat has four multi-hit contests in nine playoff games this year and seems to be settling into this series at precisely the right moment. Over the three games in Boston, Brantley collected five hits, four RBI, three hits, one double, and averaged 10.3 FPPG.

Christian Arroyo ($4,000)

There is no reason for Christian Arroyo to cost only $4,000 for this Showdown contest, but I will gladly accept the free square and continue to build my lineup. He has a hit in four of five games with three runs and three RBI, and two of his hits have gone for a triple and a home run. Arroyo feels like a must-have bat for any cash-game lineup on Friday.

Other Options: Enrique Hernandez ($9,800), Jose Altuve ($9,400) Kyle Tucker ($9,200), Xander Bogaerts ($8,200), Carlos Correa ($7,400)

 

MLB DFS News and Injury Alerts




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REAL-TIME FANTASY NEWS

Mike Trout

Angels Open to Mike Trout Playing Center Field in 2026
Victor Wembanyama

Coming off the Bench on Tuesday Night
Rudy Gobert

Not on the Injury Report for Wednesday
Anthony Edwards

on the Injury Report Again for Wednesday Night
Ja Morant

Questionable for Wednesday's Meeting With Timberwolves
Saquon Barkley

Misses Practice With Stinger
RJ Harvey

Dealing With Rib Injury
Josh Jacobs

Intends to Play Against Bears on Saturday
Zach Bogosian

Misses Tuesday's Game
Marcus Johansson

Unavailable Tuesday
Artyom Levshunov

Scratched for Tuesday
Mathew Barzal

a Game-Time Call Tuesday
Joseph Woll

Returns to Action Tuesday
Mike Matheson

Won't Play on Tuesday
Rasmus Ristolainen

Makes Season Debut Tuesday
Bam Knight

Cardinals Place Bam Knight on Injured Reserve
CFB

Kansas State's Jayce Brown Intends to Transfer
CFB

Nation's Leading Passer Drew Mestemaker to Enter Transfer Portal
Justin Crawford

Phillies Planning to Start Justin Crawford in Center Field
CFB

Jayden Maiava Signs New Deal to Return to USC
CFB

Aidan Mizell Won't Return to Florida, Entering Transfer Portal
CFB

East Carolina Targeting Jordan Davis as Next Offensive Coordinator
Patrick Mahomes

Targeting Week 1 Return in 2026
Cutter Gauthier

Scores Twice at MSG
CFB

Michigan QB Jadyn Davis Set to Enter Transfer Portal
CFB

Travis Williams Joining Texas A&M Defensive Staff
Tim Stützle

Tim Stutzle Records Three Assists in Dramatic Win
Filip Forsberg

Nets 11th Career Hat Trick
Sam Reinhart

Pots Two Goals Against Lightning
Darcy Kuemper

Hurt Versus Stars
Gustav Forsling

Injured in Monday's Win
Brandon Hagel

Makes Early Exit Monday
Cooper Flagg

Becomes Youngest 40-Point Scorer in NBA History
Victor Wembanyama

May Come Off the Bench Again Tuesday
Nikola Jović

Nikola Jovic to Undergo MRI Tuesday
Sam Hauser

Tweaks Left Ankle Monday
Peyton Watson

Not Expected to Be Out Long-Term
Ja Morant

Injures Ankle in Monday's Win
Darren Waller

Hauls in Two Touchdowns in Monday Night Loss
Brandon Clarke

Still Out Monday
Rome Odunze

Considered Week-to-Week With Foot Injury
James Harden

Officially Active on Monday Night
Ja Morant

to Remain Under Minutes Restriction Monday
James Harden

a Game-Time Call Monday
John Konchar

to Be Re-Evaluated in Three Weeks
Julian Strawther

Active on Monday
James Harden

Good to Go Monday
Tari Eason

Remains Out Monday
Daniel Gafford

to Be Limited to 17-20 Minutes Monday
Davante Adams

Considered Week-to-Week With Hamstring Injury
Kyle Filipowski

Starting Against Mavericks
Brandon Williams

Out Monday
Jaylen Warren

to Play Through Illness on Monday Night
Will Smith

Sharks Place Will Smith on Injured Reserve
Andrei Vasilevskiy

Expected to Return Before Christmas
Dylan Holloway

to Miss Six Weeks
Patrick Kane

Expected to Miss at Least Two Games
Quinton Byfield

Ruled Out for Monday
Mika Zibanejad

Won't Play on Monday
Connor Bedard

Out Until 2026
Bhayshul Tuten

to Miss a Few Weeks With Finger Injury
Joe Burrow

Will Start the Rest of the Season
Jayden Daniels

to be Shut Down for Final Three Games
Philip Rivers

Will Start Again in Week 16
Drake London

Falcons "Very Hopeful" Drake London Can Return in Week 16
CFB

Dylan Raiola Entering His Name into Transfer Portal
Micah Parsons

MRI Confirms Torn ACL for Micah Parsons
CFB

Cincinnati's Brendan Sorsby Plans to Transfer When Portal Opens
Adolis García

Adolis Garcia, Phillies Finalizing One-Year Deal on Monday
Jaylen Warren

Questionable for Monday Night Due to Illness
Bam Knight

has "Bad Sprain," Unlikely to Play in Week 16
Brandon Royval

Suffers First-Round TKO Loss
CFB

Baylor, LSU, Miami Among Potential Suitors for DJ Lagway
CFB

Aidan Chiles Will Enter Transfer Portal
Manel Kape

Shines At UFC Vegas 112
New York Jets

Jets Fire Defensive Coordinator Steve Wilks
Kevin Vallejos

Gets Second-Round Knockout Win
Christian Watson

Avoids Long-Term Injury, Status for Week 16 Unclear
Giga Chikadze

Suffers His First Career Knockout Loss
CFB

Quarterback DJ Lagway Entering Transfer Portal
Cesar Almeida

Gets Dominated
Cezary Oleksiejczuk

Wins Sixth Fight In A Row
Teddye Buchanan

Ravens Linebacker Teddye Buchanan Believed to Have Torn ACL
Morgan Charrière

Morgan Charriere Suffers First-Round Knockout Loss
Melquizael Costa

Gets First-Round Knockout Win
Marcus Buchecha

Still Winless In The UFC
Kennedy Nzechukwu

And Marcus Buchecha Fight To Draw
Lance Gibson jr

Lance Gibson Jr. Drops Decision In His UFC Debut
King Green

Gets Back In The Win Column
Dallas Goedert

has Third Two-Touchdown Game on Sunday
Kenley Jansen

Agrees to One-Year Deal With Tigers
Merrill Kelly

Returns to Diamondbacks on Two-Year Deal
Jorge Polanco

Agrees to Two-Year Deal With Mets
CFB

LaNorris Sellers to Return to South Carolina in 2026
CFB

Washington State Expected to Hire Kirby Moore as Next Head Coach
CFB

Kyle Whittingham Stepping Down as Utah Head Coach
Manel Kape

Set For UFC Vegas 112 Main Event
Brandon Royval

An Underdog At UFC Vegas 112
Kevin Vallejos

Set For His Third UFC Fight
Giga Chikadze

In Dire Need Of Victory
Cesar Almeida

Set To Welcome Cezary Oleksiejczuk To The UFC
Cezary Oleksiejczuk

Set To Make His UFC Debut
Maikel Garcia

Royals Agree on Five-Year Extension
Melquizael Costa

Looks To Extend His Win Streak
Morgan Charrière

Morgan Charriere Looks to Win Second Consecutive Fights
Marcus Buchecha

Looks To Bounce Back
CFB

Sherrone Moore Charged with Home Invasion, Among Other Charges
CFB

Freddie Kitchens Fired from North Carolina Coaching Staff
CFB

Bryce Underwood Could Leave Michigan Without Buyout
Fernando Tatis Jr.

Padres Not Considering Trading Fernando Tatis Jr.
Tarik Skubal

Tigers Engaged in "Serious Talks" Around Trading Tarik Skubal at the Winter Meetings
CFB

Chris Brazzell II Declaring for NFL Draft
CFB

Fernando Mendoza Named AP College Football Player of the Year
Raisel Iglesias

to Remain the Braves Closer
Robert Suarez

Agrees on Three-Year Deal With Braves
CFB

Sherrone Moore Remains in Police Custody
Si Woo Kim

Closes 2025 With Strong Finish Among Putting Woes
Akshay Bhatia

Looks to Rebound in 2026 After Down Year Off the Tee
Brian Harman

2025 Season a Step Back Despite Spring Win
Sam Burns

' Elite Putting Headlines a Solid 2025 Season
Sepp Straka

Ends Stellar 2025 Campaign on a High Note
Robert MacIntyre

Closes Out a Steady 2025 Campaign

RANKINGS

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RB
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K
DEF
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1B
2B
3B
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OF
SP
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