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DraftKings and FanDuel Daily Fantasy Basketball Picks (10/21/22): NBA DFS Lineups

The top daily fantasy basketball lineup picks for DraftKings and FanDuel on October 21st, 2022. John Brubaker provides NBA DFS analysis and sleeper picks for building optimal DFS rosters.

Happy Friday, RotoBallers! The NBA season is finally here, and we have a whopping 11 games slotted for this evening. It's a new season, with players switching teams, rookies joining the fold, and rotations mixing and matching as teams learn to gel. My model will take time to adjust to these changes, but it's my duty to give you all the best picks possible. I had a nice night on opening night, so I'll look to keep that momentum going forward into today. 

Tonight, we have an 11-game slate for the first weekend slate of the season. With both FanDuel and DraftKings having multi-position eligibility players, and we'll have to attack slates accordingly to make our lineups as optimal as possible. That's where I come in! I'll look to find my personal top plays and values for tonight's slate. Things can change during the day as well, so I'll do my best to update as news comes out!

Here are my daily fantasy basketball lineup picks for FanDuel and DraftKings on 10/21/22. Keep an eye on RotoBaller’s NBA injury news and also our full NBA injury report today to stay up to date before lineups are locked.

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DraftKings and FanDuel Guards - NBA DFS Lineup Picks

Devin Booker, at POR (FD: $8,300, DK: $8,900)

I'll start off tonight's slate with Devin Booker. Booker had a solid opening night on Monday night, logging 28 points, four rebounds, and nine assists across 40 minutes in what was an improbable comeback against the Mavericks. I'm looking for more of the same from him tonight, as my model projects him for 34 minutes and a usage rate of 30.18%. He'll take on the Blazers, who rank 19th in shooting guard efficiency, and this should end up a high-scoring affair.

Tyrese Haliburton, vs SAS (FD: $7,900, DK: $7,900)

I'll take a look at Tyrese Haliburton tonight as well, as the Pacers will take on the Spurs in what my buddy referred to as "the Tank Olympics." Haliburton logged 35 minutes in the season opener against the Wizards, finishing with a stat line of 26 points, four rebounds, and seven assists. My model has him projected for 36.3 minutes tonight and a 22.5% usage rate. I think that usage rate will go up as the season goes on, and this should be another high-scoring game with a total sitting at 231.5.

Coby White, at WAS (FD: $3,700, DK: $4,100)

I'll finish things up at the guard positions with Coby White. White, who is coming off the bench as a backup for Ayo Dosunmu, logged ten points and two rebounds across 24 minutes on Wednesday night. I have him projected for 27.8 minutes tonight against the Wizards though, as well as a usage rate near 18%. I wouldn't recommend this play in cash, but I do think he could be a sneaky GPP play as he comes in super cheap and has projections north of 5x on both sites.

Also consider: Kyle Lowry (FD: $5,300, DK: $5,400), Tyler Herro (FD: $6,200, DK: $6,300)

 

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DraftKings and FanDuel Forwards - NBA DFS Lineup Picks

Pascal Siakam, at BKN (FD: $8,500, DK: $8,100)

I'll start off the forwards with "Spicy P" Pascal Siakam, whom I was very high on Wednesday night. Siakam grabbed a double-double in the Raptors' season opener against the Cavs, login 23 points, 11 rebounds, and an assist. I have him projected for 37 minutes tonight with a 32% usage rate, and after seeing what Zion Williamson did to Ben Simmons on Wednesday night, I'm confident in "running it back" with Siakam.

Bojan Bogdanovic, at NY (FD: $4,900, DK: $5,600)

Another "run-back" play here for me, as we'll take a look at Bojan Bogdanovic. After a slow start Wednesday night, Bogdanovic began to heat up and finished with 24 points, five rebounds, and two assists. While I'm not expecting the same results as Wednesday, I do have Bogdanovic projected for 32.9 minutes and a usage rate of 21.67%. His matchup against the Knicks is somewhat in the "middle of the pack," but they ranked 19th in small forward efficiency last season, so I'll look for him to take advantage.

Santi Aldama, at HOU (FD: $4,300, DK: $5,100)

One of the more surprising players of Wednesday night's slate was Santi Aldama. Aldama filled in nicely for Jaren Jackson Jr. against the Knicks, logging 18 points, 11 rebounds, and an assist across 38 minutes. I don't expect him to play 38 minutes tonight, and while my model isn't currently adjusted for his minutes (having him at just a 21.9-minute projection), his 19.94% usage rate is solid enough to pass given his cheap price on both sites.

Also consider: John Collins (FD: $6,100, DK: $6,200), Aaron Gordon (FD: $5,500, DK: $6,200)

 

DraftKings and FanDuel Centers - NBA DFS Lineup Picks

Nikola Jokic, at GSW (FD: $11,300, DK: $11,200)

I, for some reason, was higher on Clint Capela than Jokic on Wednesday night, and boy will I not make that mistake again. While the Nuggets flopped in their season opener, Jokic still logged 27 points, four rebounds, and six assists across 33 minutes against the Jazz. Tonight I have him projected for 34.2 minutes, and I doubt his 32.51% usage rate will waiver as it seems the Nuggets are easing Michael Porter Jr. and Jamal Murray into the fold. I'll look for Joker and the Nuggets to bounce back against the defending champs after what has to be considered an embarrassing loss in their season opener.

Also consider: Deandre Ayton (FD: $7,000, DK: $6,600)



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REAL-TIME FANTASY NEWS

Sean Murphy

Lands on 10-Day Injured List
Bryce Miller

Placed on 15-Day Injured List With Oblique Strain
Lars Nootbaar

Will Begin the Season on 60-Day Injured List
Jackson Holliday

Placed on 10-Day Injured List
New York Jets

Ty Simpson to Hold Private Workout With Jets on Friday
Ronnie Rivers

Rams Re-Sign Ronnie Rivers to One-Year Deal
Las Vegas Raiders

Raiders to Host Fernando Mendoza for a Top-30 Visit in Two Weeks
Tua Tagovailoa

Open to Being a QB Mentor in Atlanta
Zay Flowers

Ravens Want to Extend Zay Flowers Soon
Jeremy Peña

Jeremy Pena on the Astros Opening Day Roster
Blake Snell

Dodgers Place Blake Snell on 15-Day Injured List
John Carlson

Sets Up Three Goals Tuesday Night
Joel Hofer

Picks Up Sixth Shutout of the Season
John Tavares

Records Three Assists in Tuesday's Win
NJ

Arseni Gritsyuk Scheduled for Imaging Wednesday
Jordan Mason

Could Benefit from Quarterback Change
Tony DeAngelo

Suffers Lower-Body Injury Tuesday
Aaron Rodgers

Mike McCarthy Would Welcome an Aaron Rodgers Reunion
Emmitt Finnie

Enters Concussion Protocol
Ryan Fox

a High-Upside Value in Houston
Barrett Hayton

Sustains Upper-Body Injury Tuesday
Dak Prescott

Remains Egregiously Undervalued
Marco Penge

a Boom-or-Bust Option in Houston
Cedric Coward

Returns From Three-Game Absence
CeeDee Lamb

Cowboys' Offensive Cohesion Could Lead to Another Big Year from CeeDee Lamb
Jaylen Wells

Won't Play Against Spurs
NFL

Jeremiyah Love Does Not Participate at Notre Dame Pro Day
Ty Jerome

Unavailable Wednesday
Brice Sensabaugh

Resting on Wednesday
Kyle Filipowski

Dealing With Illness, Unlikely to Play Wednesday
Jakob Poeltl

Could Miss Another Game Wednesday
Immanuel Quickley

Questionable Wednesday
Puka Nacua

Accused of Biting a Woman, Making Antisemitic Remarks
Aaron Rai

Looks to Bounce Back in Houston
Luther Burden III

Ascending Into Major Role on Offense?
Jason Day

a Volatile Option at the Texas Children's Houston Open
Joe Mixon

Remains a Free Agent as April Approaches
Kirby Yates

Angels Place Kirby Yates on 15-Day Injured List
Elijah Moore

Eagles Sign Elijah Moore to a One-Year Deal
Harris English

Eyes a Bounce-Back at the Texas Children's Houston Open
Ben Griffin

Looks for Turnaround at the Texas Children's Houston Open
Kirk Cousins

an Option as Backup Quarterback in Green Bay?
Zach Wilson

Saints Sign Zach Wilson to a One-Year Deal
Rickie Fowler

Brings Strong Form Into Texas Children's Houston Open
Brandon Clarke

to Miss Rest of Season
Ja Morant

Done for the Season
Brady Tkachuk

Collects Two More Points on Tuesday
Royce O'Neale

Available Tuesday Night
Grayson Allen

Cleared for Action Tuesday
Martin Necas

Scores Twice Against Penguins
Brandon Ingram

Questionable for Wednesday's Game
Ryan Dunn

Won't Play Against Nuggets
Paul George

Officially Available Wednesday
Nick Lodolo

Will Open 2026 on the Injured List Due to Finger Ailment
Pete Crow-Armstrong

Agrees to Six-Year, $115 Million Extension With the Cubs
John Collins

is Returning on Wednesday
Jordan Miller

is Questionable for Wednesday's Game
Bennedict Mathurin

is Returning on Wednesday
Kawhi Leonard

is Uncertain for Wednesday's Game
Kyle Kuzma

Carries Questionable Tag for Wednesday
Bobby Portis

is Tagged as Questionable for Wednesday
Kevin Porter Jr.

to Miss Fourth Straight Game
Igor Chernyshov

Returns to Sharks Lineup
Dylan Larkin

Good to Go Tuesday
Ross Colton

Logan O'Connor, Ross Colton Available Tuesday
Morgan Rielly

Back in Action Tuesday
Joel Eriksson Ek

Kirill Kaprizov, Joel Eriksson Ek Returning Tuesday
Thomas Chabot

to Be "Out a While"
Evgeni Malkin

Out Against Avalanche Tuesday
Joe Flacco

Reaches Agreement to Return to Bengals
Marvin Mims Jr.

Now a Trade Candidate in Denver?
Francisco Lindor

Likely to be Ready for Opening Day
Ryan Gerard

Can Continue Rolling at Texas Children's Houston Open
Pierceson Coody

Bounces Back at Valspar Championship
Rasmus Hojgaard

Trying to Get Back on Track at Texas Children's Houston Open
Michael Thorbjornsen

Playing Well Heading to Texas Children's Houston Open
Harry Hall

Looking for Consistency at Texas Children's Houston Open
Brooks Koepka

Continues Building Momentum
Odell Beckham Jr.

Plans to Play in 2026
RJ Harvey

Ready for a Year 2 Jump?
Baker Mayfield

Buccaneers Expected to Discuss Extension With Baker Mayfield This Offseason
Roki Sasaki

to Stick in Rotation Despite Spring Struggles
Kevin McGonigle

Makes Tigers Opening Day Roster
Scottie Scheffler

Withdraws From Texas Children's Houston Open
James Reimer

Picks Up Victory Against Rangers
Ryan Pepiot

Placed on Injured List to Open the Season
J.J. Wetherholt

JJ Wetherholt Likely to Hit Leadoff on Opening Day
Connelly Early

to Make First Start on Sunday
Luke Clanton

Might Have a Problem in Houston
Sam Stevens

Happy to See Houston This Week
Keith Mitchell

Tries to Rebound After The Players Championship
Will Zalatoris

Returning This Week at Houston
Wyndham Clark

Trending in the Wrong Direction Heading to Houston
Shane Lowry

Seeking Better Luck in Houston This Weekend
Kurt Kitayama

Poised to Bounce Back at the Houston Open
Pete Crow-Armstrong

Cubs, Pete Crow-Armstrong Finalizing Long-Term Extension
Shane Pinto

Opens Scoring Versus Rangers
Blake Snell

Targeting a May Return
Hunter Greene

Reds Place Hunter Greene on 60-Day Injured List
J.J. Wetherholt

JJ Wetherholt Makes Cardinals Opening Day Roster
Nick Pivetta

to Start on Opening Day for Padres
Brandon Woodruff

Makes Brewers Opening Day Rotation
Lerone Murphy

Suffers His First Loss
Movsar Evloev

Edges Out Lerone Murphy
CFB

Notre Dame Ranks No. 1 in Returning Production for 2026
Michael Aswell

Jr. Drops Decision At UFC London
Michael Aswell

Luke Riley Outclasses Michael Aswell Jr.
Sam Patterson

Suffers Unanimous-Decision Loss
Michael Page

Wins Lackluster Decision
Austen Lane

Suffers First-Round TKO Loss
Iwo Baraniewski

Delivers 28-Second TKO
Lawson Crouse

Picks Up Three Points in Overtime Win
Filip Forsberg

Takes Predators Past Blackhawks
Alex Ovechkin

Scores 1,000th Career Goal
Tyler Reddick

Overcomes Adversity for Fourth Victory of the Season At Darlington
Brad Keselowski

Falls Short of Darlington Victory Despite Domination
Ryan Blaney

Recovers From Pit-Road Struggles to Score Career-Best Darlington Finish
Carson Hocevar

Rallies to Finish Fourth at Darlington
Kyle Larson

Decent Performance Ends with Technical Issues At Darlington
Tyler Reddick

the Clear Favorite at Darlington
Kyle Larson

a High-Risk, High-Reward Driver at Darlington
Ryan Blaney

Is Getting Better at Darlington
NASCAR

Bubba Wallace Not Slowing Down at Darlington
Chris Buescher

Should be a Top-10 Contender at Darlington
Austin Cindric

a Sleeper at Darlington
Erik Jones

Quickest in Practice at Darlington
Denny Hamlin

Qualifies Ninth for this Week's Cup Race at Darlington
Chase Briscoe

Is One of the Top DFS Options of the Week for Darlington
William Byron

Is William Byron A Playable DFS Option for Darlington Lineups?
Christopher Bell

Could Christopher Bell be Considered A Decent DFS Option for Darlington?
Chase Elliott

Is Chase Elliott Worth Rostering At Darlington This Week For DFS?
Joey Logano

May Not Have the Speed to Warrant A Darlington DFS Lineup Spot
Ross Chastain

Should DFS Players Trust Ross Chastain at Darlington?
Kyle Busch

Could Kyle Busch Be A Worthy DFS Option for Darlington?
Brad Keselowski

May be A Contriarian DFS Tournament Option At Darlington
Lerone Murphy

Set For UFC London Main Event
Movsar Evloev

Looks To Remain Unbeaten
Michael Aswell

Jr. An Underdog At UFC London
Luke Riley

Set For UFC London Co-Main Event
Sam Patterson

Looks To Extend His Win Streak
Michael Page

Set For Welterweight Bout
Austen Lane

In Dire Need Of Victory
Iwo Baraniewski

A Favorite At UFC London
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