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DraftKings and FanDuel Daily Fantasy Basketball Picks (10/21/22): NBA DFS Lineups

The top daily fantasy basketball lineup picks for DraftKings and FanDuel on October 21st, 2022. John Brubaker provides NBA DFS analysis and sleeper picks for building optimal DFS rosters.

Happy Friday, RotoBallers! The NBA season is finally here, and we have a whopping 11 games slotted for this evening. It's a new season, with players switching teams, rookies joining the fold, and rotations mixing and matching as teams learn to gel. My model will take time to adjust to these changes, but it's my duty to give you all the best picks possible. I had a nice night on opening night, so I'll look to keep that momentum going forward into today. 

Tonight, we have an 11-game slate for the first weekend slate of the season. With both FanDuel and DraftKings having multi-position eligibility players, and we'll have to attack slates accordingly to make our lineups as optimal as possible. That's where I come in! I'll look to find my personal top plays and values for tonight's slate. Things can change during the day as well, so I'll do my best to update as news comes out!

Here are my daily fantasy basketball lineup picks for FanDuel and DraftKings on 10/21/22. Keep an eye on RotoBaller’s NBA injury news and also our full NBA injury report today to stay up to date before lineups are locked.

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DraftKings and FanDuel Guards - NBA DFS Lineup Picks

Devin Booker, at POR (FD: $8,300, DK: $8,900)

I'll start off tonight's slate with Devin Booker. Booker had a solid opening night on Monday night, logging 28 points, four rebounds, and nine assists across 40 minutes in what was an improbable comeback against the Mavericks. I'm looking for more of the same from him tonight, as my model projects him for 34 minutes and a usage rate of 30.18%. He'll take on the Blazers, who rank 19th in shooting guard efficiency, and this should end up a high-scoring affair.

Tyrese Haliburton, vs SAS (FD: $7,900, DK: $7,900)

I'll take a look at Tyrese Haliburton tonight as well, as the Pacers will take on the Spurs in what my buddy referred to as "the Tank Olympics." Haliburton logged 35 minutes in the season opener against the Wizards, finishing with a stat line of 26 points, four rebounds, and seven assists. My model has him projected for 36.3 minutes tonight and a 22.5% usage rate. I think that usage rate will go up as the season goes on, and this should be another high-scoring game with a total sitting at 231.5.

Coby White, at WAS (FD: $3,700, DK: $4,100)

I'll finish things up at the guard positions with Coby White. White, who is coming off the bench as a backup for Ayo Dosunmu, logged ten points and two rebounds across 24 minutes on Wednesday night. I have him projected for 27.8 minutes tonight against the Wizards though, as well as a usage rate near 18%. I wouldn't recommend this play in cash, but I do think he could be a sneaky GPP play as he comes in super cheap and has projections north of 5x on both sites.

Also consider: Kyle Lowry (FD: $5,300, DK: $5,400), Tyler Herro (FD: $6,200, DK: $6,300)

 

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DraftKings and FanDuel Forwards - NBA DFS Lineup Picks

Pascal Siakam, at BKN (FD: $8,500, DK: $8,100)

I'll start off the forwards with "Spicy P" Pascal Siakam, whom I was very high on Wednesday night. Siakam grabbed a double-double in the Raptors' season opener against the Cavs, login 23 points, 11 rebounds, and an assist. I have him projected for 37 minutes tonight with a 32% usage rate, and after seeing what Zion Williamson did to Ben Simmons on Wednesday night, I'm confident in "running it back" with Siakam.

Bojan Bogdanovic, at NY (FD: $4,900, DK: $5,600)

Another "run-back" play here for me, as we'll take a look at Bojan Bogdanovic. After a slow start Wednesday night, Bogdanovic began to heat up and finished with 24 points, five rebounds, and two assists. While I'm not expecting the same results as Wednesday, I do have Bogdanovic projected for 32.9 minutes and a usage rate of 21.67%. His matchup against the Knicks is somewhat in the "middle of the pack," but they ranked 19th in small forward efficiency last season, so I'll look for him to take advantage.

Santi Aldama, at HOU (FD: $4,300, DK: $5,100)

One of the more surprising players of Wednesday night's slate was Santi Aldama. Aldama filled in nicely for Jaren Jackson Jr. against the Knicks, logging 18 points, 11 rebounds, and an assist across 38 minutes. I don't expect him to play 38 minutes tonight, and while my model isn't currently adjusted for his minutes (having him at just a 21.9-minute projection), his 19.94% usage rate is solid enough to pass given his cheap price on both sites.

Also consider: John Collins (FD: $6,100, DK: $6,200), Aaron Gordon (FD: $5,500, DK: $6,200)

 

DraftKings and FanDuel Centers - NBA DFS Lineup Picks

Nikola Jokic, at GSW (FD: $11,300, DK: $11,200)

I, for some reason, was higher on Clint Capela than Jokic on Wednesday night, and boy will I not make that mistake again. While the Nuggets flopped in their season opener, Jokic still logged 27 points, four rebounds, and six assists across 33 minutes against the Jazz. Tonight I have him projected for 34.2 minutes, and I doubt his 32.51% usage rate will waiver as it seems the Nuggets are easing Michael Porter Jr. and Jamal Murray into the fold. I'll look for Joker and the Nuggets to bounce back against the defending champs after what has to be considered an embarrassing loss in their season opener.

Also consider: Deandre Ayton (FD: $7,000, DK: $6,600)



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REAL-TIME FANTASY NEWS

Randal Grichuk

Joins Yankees on Minor-League Deal
Cam Schlittler

Faces Live Hitters on Wednesday
Keegan Murray

Won't Return on Wednesday Night
Jayson Tatum

a "Full Go" in Five-on-Five Scrimmages
Will Warren

has Promising Spring Training Debut
Andrew Abbott

Goes Two Innings in Spring Training Debut
Pascal Siakam

Likely to Miss Second Straight Game
Joel Embiid

On Track to Suit Up Thursday
Kyler Murray

Prefers to be Released
Jalen Johnson

Could Miss Thursday's Rematch
Devin Carter

Ready to Go vs. Houston
Derek Carr

"Strong Belief" That Derek Carr is "Very Serious" About Unretiring
James Harden

Will Not Play in Milwaukee
Dorian Finney-Smith

Sitting Wednesday vs. Kings
Scottie Barnes

Set to Suit Up Wednesday
Kyle Anderson

Remains Sidelined vs. Warriors
Alex Caruso

Sidelined Wednesday vs. Pistons
Al Horford

Good to Go Wednesday
Isaiah Hartenstein

Chet Holmgren to Miss Matchup with Pistons
Konnor Griffin

Exits Early After Being Hit in the Foot
Konnor Griffin

Open to Long-Term Extension With Pirates
Triston Casas

Thinks he Could be Ready by Opening Day
Brenton Doyle

Scratched on Wednesday With Wrist Inflammation
Draymond Green

Sidelined Against Memphis
Merrill Kelly

Won't be Ready for Opening Day
Mikael Granlund

Leo Carlsson In, Mikael Granlund Out for Ducks Wednesday
De'Anthony Melton

Ruled Out Wednesday
River Ryan

Making a Case for Starting Role
Luisangel Acuña

Luisangel Acuna Leaves Early With a Cut Above his Eye
Connor McDavid

Ready to Play Wednesday
John Carlson

Out Wednesday
Donovan Mitchell

Ruled Out Wednesday
Roope Hintz

Misses Wednesday's Action Due to Illness
Shea Theodore

Unavailable Wednesday
Evan Mobley

Sidelined for Wednesday's Matchup With Milwaukee
Mark Stone

Mitch Marner Won't Play Wednesday
Logan Cooley

on Track to Return Wednesday
Sidney Crosby

Set to Miss Four Weeks
James Harden

Plans to Play Through Fractured Right Thumb Wednesday
Robert Garcia

Could Emerge as the Preferred Ninth-Inning Option in Texas
Andy Dalton

Is Andy Dalton Available for a Trade?
Brendan Rodgers

Injures Shoulder in Spring Training Game
Chase DeLauter

Scratched on Wednesday With Lower-Body Soreness
Ryan O'Hearn

Could See a Career High in Plate Appearances in 2026
Bailey Ober

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J.P. Crawford

has Minor Shoulder Injury
Troy Melton

Dealing With Arm Soreness
Patrick Sandoval

has "Eye-Opening" Batting Practice Session
Francisco Lindor

to Restart "Impact" Activities in 2-3 Days
Paul Skenes

Expects to Make Two Starts in World Baseball Classic
Keith Mitchell

Making The Comfortable Return to PGA National
CFB

Chandler Morris Suing NCAA for Seventh Year of Eligibility
Chris Kirk

Searching for a Spark at Cognizant Classic
Brooks Koepka

Making Third PGA Tour Start at Cognizant Classic
Mackenzie Hughes

a Steady Option at Cognizant Classic
Seamus Power

Seeking More Green in Florida
PGA

Haotong Li Back From a Break as Florida Stretch Starts
Stephan Jaeger

Trying to Put Four Rounds Together in Florida
Ty Jerome

Available Wednesday
PGA

Nico Echavarria Again Attempting to Make the Weekend
Amen Thompson

Won't Play Wednesday
Jamal Murray

Probable Wednesday
Patrick Fishburn

Looking for a Spark at Cognizant Classic
Blades Brown

Set for Cognizant Classic Debut
Michael Thorbjornsen

Looking to Bounce Back at Cognizant Classic
Maxx Crosby

Raiders Expect Maxx Crosby to Return
Nino Niederreiter

Out Week-to-Week
Neal Pionk

Out Week-to-Week With New Injury
Noah Hanifin

Unavailable Wednesday
Jack Eichel

to Miss Wednesday's Action
John Tavares

Expected to Play Wednesday
Samuel Girard

Penguins Acquire Samuel Girard From Avalanche
Victor Hedman

Good to Go for Wednesday
Brayden Point

Available for Lightning
Mikko Rantanen

to Miss at Least Two Weeks
Billy Horschel

Looks to Improve Season at Cognizant Classic
Kyle Pitts Sr.

Falcons Place Franchise Tag on Kyle Pitts Sr.
Joe Highsmith

Returns to Defend at Cognizant Classic
Quinshon Judkins

Out of Walking Boot, Will be Ready for Training Camp
Breece Hall

Jets Will Use Franchise Tag on Breece Hall if Extension isn't Reached
Joel Dahmen

Needs Better Consistency Heading Into The Florida Swing
Daniel Berger

Looks to Improve Putting as PGA Tour Begins Its Florida Swing
Kirk Cousins

Falcons Plan to Release Kirk Cousins
Zach Ertz

Plans to Return for 14th Season
Davis Thompson

Struggling to Find Birdies as Florida Looms
Tom Kim

Not Quite Cutting It in 2026
Nicolai Hojgaard

Wants to Build Momentum from Scottsdale
Christiaan Bezuidenhout

Returns After Extended Break for Florida Event
CFB

Gunner Rivers Follows His Father, Commits To North Carolina State
Will Zalatoris

Set to Make Tournament Debut at Cognizant Classic
Linus Ullmark

Available for Senators
Rasmus Hojgaard

Trending Up at the Cognizant Classic
Ryan Reaves

Sharks Activate Ryan Reaves From Injured Reserve
Charlie Lindgren

Activated From Injured Reserve Monday
Josh Norris

Cleared to Return Wednesday
Anthony Hernandez

Suffers Third-Round TKO Loss
Sean Strickland

Gets Back In The Win Column
Kyle Pitts Sr.

Falcons Planning to Use Franchise Tag on Kyle Pitts Sr.
Geoff Neal

Suffers Back-To-Back Knockout Losses
Uros Medic

Shines At UFC Houston
Dan Ige

Gets Finished For The First Time In His Career
Melquizael Costa

Extends His Win Streak To Six
NASCAR

Bubba Wallace Falls Short of Victory at EchoPark Speedway
Carson Hocevar

Rallies to Fourth At EchoPark Speedway After Early Struggles
Ross Chastain

Finishes Third At EchoPark Speedway
Chase Briscoe

Scores First Career Top-Five Finish at EchoPark Speedway
Tyler Reddick

Nabs His Second Win of the Season At EchoPark Speedway
Joey Logano

Will Be Popular DFS Pick at EchoPark Speedway
Tyler Reddick

on Pole After Qualifying Rained Out at EchoPark Speedway
Chase Elliott

Could Chase Elliott Be Worth Rostering At EchoPark Speedway?
Ryan Blaney

Is Ryan Blaney Worth Rostering for DFS at EchoPark Speedway?
William Byron

Is William Byron Worth Rostering for DFS at EchoPark Speedway?
Rondale Moore

Passes Away
Denny Hamlin

Is Worth Consideration for EchoPark Speedway DFS Lineups
Brad Keselowski

Is A Tournament Option for DFS At EchoPark Speedway
NASCAR

Is Bubba Wallace Rosterable In DFS At EchoPark Speedway?
Austin Cindric

Should DFS Managers Roster Austin Cindric at EchoPark Speedway?
Ross Chastain

Is Ross Chastain A Sneaky DFS Option for EchoPark Speedway?
Ricky Stenhouse Jr

Is Ricky Stenhouse Jr. Worth Rostering for DFS at EchoPark Speedway?
Alex Bowman

Will Start Towards the Rear At EchoPark Speedway
Javonte Williams

Cowboys Sign Javonte Williams to Three-Year, $24 Million Extension
Travis Etienne Jr.

has "Legitimate Interest" in Joining Chiefs
Zach Charbonnet

Undergoes Knee Surgery on Friday
CFB

Curt Cignetti Agrees to New Deal With Indiana, Will Earn $13.2 Million Per Year
Anthony Hernandez

Set For UFC Houston Main Event
Sean Strickland

Looks To Get Back In The Win Column
Uros Medic

Set For UFC Houston Co-Main Event
Geoff Neal

Looks To Get Back In The Win Column
Melquizael Costa

A Favorite At UFC Houston
Dan Ige

An Underdog At UFC Houston
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