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DraftKings Lineup Picks (Week 1) - NFL DFS Advice

Welcome to Week 1 of the NFL season! Football is finally back and we are setup for a great DFS season. There are tons of contests on both major DFS sites, and this is the time of year to cash in. Below are my DraftKings DFS Lineup Picks for Week 1.

There are some clear top options at every position, but if you are looking to save some money to jam the big guys in, you will want to take note of some players I mentioned. The Bucs vs. Dolphins game may be cancelled or moved due to the hurricane, so be sure to follow that. Sit back, read up, and let's have a successful first week of the NFL.

These DraftKings lineup recommendations are based on match ups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 1. Good luck with your DraftKings DFS lineups!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 1 Picks

Carson Wentz - PHI @ WAS (DK $5,300)

Wentz present himself as a very interesting option in Week 1, as he isn't too expensive, and finds himself in a solid match up. Last season the Redskins had the 24th DVOA vs the pass, and with a game total set at 47.5, we could see this turn into a bit of a shootout. In his last game vs the Redskins last year, Wentz threw for 314 yards, 1 TD, 1 INT. He had a decent rookie season, where he showed his upside, but still made plenty of mistakes. Wentz put up 16.9 DraftKings points or more in five of his last seven games, so even with his mid season slump, he was able to rebound with his performance, and hopefully he can grow from that this season. Wentz also had a bit of upside through scoring points when he scrambles out of the pocket, which is never a bad thing. The Eagles added Alshon Jeffery, in the off season, which can make a nice stacking option, that shouldn't be highly owned. If you want to go cheaper, look at tight end, Zach Ertz, as a stacking option with Wentz. The Eagles are a -1 favorite right now, so with this set to be a close game, Wentz makes a strong cash game play, and his savings will allow you to spend up elsewhere.

Carson Palmer - ARI @ DET (DK $6,000)

Palmer is a mid priced quarterback this week, and because of that, he may go overlooked. He isn't on the high end, and isn't on the super cheap end, and this middle ground is where you can find an option where you don't spend too much, and still have plenty of upside, queue Carson Pamer. Any time there is an above average quarterback going against the Lions, in a game where the over/under is set at 48, you want to take a look at him. Last season the Lions were last in the league when it came to DVOA vs the pass. They simply cannot stop the pass, and with Palmer who averaged 282 yards a game, and 18.6 DraftKings points last season, he is in for a productive Sunday. The common stack you may see with Palmer, is pairing him with Larry Fitzgerald. Yes, they are both a year older, but against a defense as bad as the Lions, you should see them have success in this game. Consistency is there for cash games, and the favorable match up, gives Palmer some upside for tournaments.

 

DraftKings DFS Running Backs - Week 1 Picks

Christian McCaffrey - CAR @ SF (DK $5,400)

Start a rookie running back Week 1? Yes. We all know how electric McCaffrey was in college, and everyone is waiting to see if he can do the same in the NFL. Well he couldn't be in a better spot to get his career underway, since he is up against San Francisco, who had the 31st DVOA vs running backs last season. There is an obvious risk factor that comes along with playing a running back who has no experience, but there have been reports that say McCaffrey has his own separate playbook, and a good portion of the offense will feature him. This is a big showing by the Panthers coaching staff, and after their disappointing season last year, they need a spark to get things going. McCaffrey looked good this preseason, as he saw action in three of their four games. He ended with 14 rushes for 87 yards and 1 touchdown, along with just a few catches out of the backfield. Big time upside with him, and makes a good GPP play.

LeSean McCoy - BUF vs NYJ (DK $8,200)

McCoy may not be considered one of the two top options at running back, but he is certainly worth a roster spot. With all the news surrounding the health of the Bills quarterbacks, and considering the fact they traded away Sammy Watkins, the question becomes, where will the offense come from for the Bills? The answer is McCoy, and a whole lot of him. There are some obvious things to take note of, McCoy is up against the Jets, who had the best defense vs the run last season. McCoy did struggle in his two games vs the Jets last season, but since the Bills may be down to their third string quarterback, they could be in a spot to force feed McCoy the ball, and he can gain points over time. With risk, there can be reward, and pivoting away from the two top running backs, can get you a player at lower ownership, who is looking at a big workload.

 

DraftKings DFS Wide Receivers - Week 1 Picks

Michael Crabtree - OAK @ TEN (DK $6,000)

While Amari Cooper may be listed as the number one receiver for the Raiders, Crabtree saw the most targets last season, and is just as threatening out wide. The Raiders vs Titans game has the highest over/under of the week at 51 points. You will want to get some exposure to this game, and Crabtree is a perfect option. Not only is he cheaper than Cooper, but last season in their game vs the Titans, Crabtree had 8 catches, 102 yards, for 21.1 DraftKings points. Those are some big numbers for the 15th most expensive wide receiver this week. Crabtree had seven or more targets for the last eight weeks of the season, and against a team who had the 27th DVOA against the pass, it sets him up for a potentially big first week.

Sterling Shepard - NYG @ DAL (DK $4,100)

With both Odell Beckham Jr. and Brandon Marshall listed as questionable for the season opener, it leaves Shepard as a cheap receiving option. Now, there is still some uncertainty about the health and playing status of the mentioned receivers for the Giants, so be sure to check in on those before rosters lock. But if one or both of those players are out, Shepard is in a good spot to produce some points. The Cowboys do have a good defense against the pass, 8th DVOA, but the targets have to go somewhere for the Giants, and Shepard will be that man. He ended the season last year with 10 or more DraftKings points in three of their final four games, and really seemed to develop as a rookie. He finished with eight touchdowns, which was second highest on the team behind OBJ. Good amount of savings, with a potential for a bump in targets.

Antonio Brown - PIT @ CLE (DK $8,800)

If you are looking to spend up on wide receiver, look no further than Antonio Brown. He is a PPR machine, and playing on DraftKings, getting that full point is huge for your team. Brown is up against Cleveland, who last season, had the 29th DVOA vs the pass. They simply couldn't stop the passing game, which puts Brown in a great spot to really rack up some points. Brown averaged 21.5 DraftKings points per game, which was the best of all receivers. His price can make him tough to fit into some lineups, but his consistency and overall production, make him great in any format.

 

DraftKings DFS Tight Ends - Week 1 Picks

Delanie Walker - TEN vs OAK (DK $4,300)

Tight end is a spot where a lot of DFS players like to spend down, since the production can vary week to week, but Walker is nearly $2K cheaper than the most expensive option, and is in a good spot. He is up against the Raiders who had the 23rd DVOA vs tight ends last season. This game has the highest over/under of the week at 51 points, and with Walker being the second favorite target of Mariota last season, he is in a prime spot to score big.

Austin Hooper - ATL @ CHI (DK $3,00)

If you are truly looking to spend down at tight end, and almost a punt play, look at Hooper on Atlanta. He is listed as the number one tight end of the depth chart for the Falcons, so at least he will be on the field. The uncertainly comes from the fact he only had 22 receptions in 16 games last year. Not a huge part of the offense by any means, but is up against the Bears who had the 28th DVOA vs tight ends last year.

 

DraftKings DFS Defenses - Week 1 Picks

St. Louis Rams @ Indianapolis Colts (DK $3,200)

We all know that defense can be one of the more unpredictable plays in daily fantasy, and in searching for a team in a good spot, you will see the Rams as a top option. The Rams had the 15th overall DVOA last season, but the true upside for them comes from their match up vs the Colts. Without Andrew Luck at the helm for the Colts, they are going to be in rough shape on offense, which leaves the Rams the chance to capitalize. The Colts have the fourth lowest implied team total at 19 points, and we should see the Rams as a popular option.

 

More Week 1 Lineup Prep




REAL-TIME FANTASY NEWS

Kevin Huerter

Active on Sunday Night
Caris LeVert

Duncan Robinson, Caris LeVert Available Sunday
Dean Wade

Max Strus Replaces Dean Wade in Starting Lineup Sunday
Luke Kornet

Iffy for Monday
Larry Nance Jr.

Won't Play Sunday
De'Aaron Fox

Listed as Questionable for Monday's Action
Jalen Williams

Officially Available for Game 1 Against Spurs
Shai Gilgeous-Alexander

Named MVP for Second Straight Year
Jonah Coleman

is an Intriguing Power Back to Target in Dynasty Leagues
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Darius Slayton

Lacking Long-Term Upside for Dynasty Managers
Keaton Mitchell

a Prime Dynasty Handcuff Option Entering First Season in L.A.
Jadarian Price

Looks Like the Running Back of the Future in Seattle
Isaiah Bond

Dynasty Outlook Clouded by Uncertain Role in Cleveland
James Cook III

Remains a High-End Dynasty RB1 Entering 2026
Lamar Jackson

Poised for Bounce Back Season in 2026
Bucky Irving

Expected to Be Ready for Training Camp
Kyle Williams

Deep Threat Kyle Williams Facing Uphill Battle for Playing Time
Michael Pittman Jr.

Could Receive Short-Term Value Uptick in PPR Leagues
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Chiefs, Commanders Could Make Sense for Stefon Diggs
Will Howard

Dynasty Value Dealt a Blow
Jaylen Warren

Should Benefit From Veteran QB's Return to Pittsburgh
Drew Allar

Could Continue to Hold Dynasty Value
Pat Freiermuth

Could See a Small Dynasty Bump With Veteran QB Returning
DK Metcalf

A Dynasty Sell Candidate With Veteran QB Returning?
Bones Hyland

Wants to Stay in Minnesota
Mike Conley

Hints He Will Continue Playing Next Season
Kevin Huerter

Iffy for Sunday Night
Caris LeVert

Questionable for Game 7
Duncan Robinson

Back on Injury Report Ahead of Game 7
Larry Nance Jr.

Likely Out Sunday Due to Illness
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Aaron Rodgers

Signs One-Year Deal With Steelers
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Alex Lyon

Likely to Start Game 6 Against Canadiens
Owen Power

Available Saturday
Isaac TeSlaa

Can Isaac TeSlaa Carve Out a Larger Role in Detroit Going Forward?
Troy Franklin

Facing Uphill Battle for Playing Time in Denver
Trevor Lawrence

Should Trevor Lawrence Be Valued as a Dynasty QB1?
Courtland Sutton

in Line for Reduced Role in Denver?
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Duncan Robinson

Nets 14 Points With Four Triples
Cade Cunningham

Contributes 21 Points in Game 6 Win
Jalen Duren

Bounces Back With Double-Double
Anthony Edwards

Finishes Season-Ending Loss With 24 Points
Victor Wembanyama

Tallies 19 Points in Friday's Win
De'Aaron Fox

Highly Effective in Blowout Win
Stephon Castle

Shines in Series-Clincher
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Max Fried

Heading to Injured List With Elbow Bone Bruise
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Julian Sayin Looking To Build Off Of Strong Debut Season
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College GameDay Set for First Three Weeks
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Jeremiah Smith Aiming For Ohio State Receiving Records
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Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
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Charles Woodson Jr. Commits to Michigan
Jordan Westburg

to Have Season-Ending Elbow Surgery
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
Tarik Skubal

Resumes Playing Catch, Ahead of Schedule?
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
Pavel Dorofeyev

Enjoys Second Consecutive Multi-Goal Game
Shea Theodore

Records Two Points in Game 6 Win
Mitchell Marner

Scores Special Goal in Series-Clincher
Ryan Johnson

Takes Over as Canucks GM, Sedins Promoted to Co-Presidents
Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Quinn Hughes

Finishes Postseason With 15 Points
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
RANKINGS
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1B
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SS
OF
SP
RP

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WR
TE
K
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