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DraftKings Lineup Picks (Week 1) - NFL DFS Advice

Welcome to Week 1 of the NFL season! Football is finally back and we are setup for a great DFS season. There are tons of contests on both major DFS sites, and this is the time of year to cash in. Below are my DraftKings DFS Lineup Picks for Week 1.

There are some clear top options at every position, but if you are looking to save some money to jam the big guys in, you will want to take note of some players I mentioned. The Bucs vs. Dolphins game may be cancelled or moved due to the hurricane, so be sure to follow that. Sit back, read up, and let's have a successful first week of the NFL.

These DraftKings lineup recommendations are based on match ups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 1. Good luck with your DraftKings DFS lineups!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 1 Picks

Carson Wentz - PHI @ WAS (DK $5,300)

Wentz present himself as a very interesting option in Week 1, as he isn't too expensive, and finds himself in a solid match up. Last season the Redskins had the 24th DVOA vs the pass, and with a game total set at 47.5, we could see this turn into a bit of a shootout. In his last game vs the Redskins last year, Wentz threw for 314 yards, 1 TD, 1 INT. He had a decent rookie season, where he showed his upside, but still made plenty of mistakes. Wentz put up 16.9 DraftKings points or more in five of his last seven games, so even with his mid season slump, he was able to rebound with his performance, and hopefully he can grow from that this season. Wentz also had a bit of upside through scoring points when he scrambles out of the pocket, which is never a bad thing. The Eagles added Alshon Jeffery, in the off season, which can make a nice stacking option, that shouldn't be highly owned. If you want to go cheaper, look at tight end, Zach Ertz, as a stacking option with Wentz. The Eagles are a -1 favorite right now, so with this set to be a close game, Wentz makes a strong cash game play, and his savings will allow you to spend up elsewhere.

Carson Palmer - ARI @ DET (DK $6,000)

Palmer is a mid priced quarterback this week, and because of that, he may go overlooked. He isn't on the high end, and isn't on the super cheap end, and this middle ground is where you can find an option where you don't spend too much, and still have plenty of upside, queue Carson Pamer. Any time there is an above average quarterback going against the Lions, in a game where the over/under is set at 48, you want to take a look at him. Last season the Lions were last in the league when it came to DVOA vs the pass. They simply cannot stop the pass, and with Palmer who averaged 282 yards a game, and 18.6 DraftKings points last season, he is in for a productive Sunday. The common stack you may see with Palmer, is pairing him with Larry Fitzgerald. Yes, they are both a year older, but against a defense as bad as the Lions, you should see them have success in this game. Consistency is there for cash games, and the favorable match up, gives Palmer some upside for tournaments.

 

DraftKings DFS Running Backs - Week 1 Picks

Christian McCaffrey - CAR @ SF (DK $5,400)

Start a rookie running back Week 1? Yes. We all know how electric McCaffrey was in college, and everyone is waiting to see if he can do the same in the NFL. Well he couldn't be in a better spot to get his career underway, since he is up against San Francisco, who had the 31st DVOA vs running backs last season. There is an obvious risk factor that comes along with playing a running back who has no experience, but there have been reports that say McCaffrey has his own separate playbook, and a good portion of the offense will feature him. This is a big showing by the Panthers coaching staff, and after their disappointing season last year, they need a spark to get things going. McCaffrey looked good this preseason, as he saw action in three of their four games. He ended with 14 rushes for 87 yards and 1 touchdown, along with just a few catches out of the backfield. Big time upside with him, and makes a good GPP play.

LeSean McCoy - BUF vs NYJ (DK $8,200)

McCoy may not be considered one of the two top options at running back, but he is certainly worth a roster spot. With all the news surrounding the health of the Bills quarterbacks, and considering the fact they traded away Sammy Watkins, the question becomes, where will the offense come from for the Bills? The answer is McCoy, and a whole lot of him. There are some obvious things to take note of, McCoy is up against the Jets, who had the best defense vs the run last season. McCoy did struggle in his two games vs the Jets last season, but since the Bills may be down to their third string quarterback, they could be in a spot to force feed McCoy the ball, and he can gain points over time. With risk, there can be reward, and pivoting away from the two top running backs, can get you a player at lower ownership, who is looking at a big workload.

 

DraftKings DFS Wide Receivers - Week 1 Picks

Michael Crabtree - OAK @ TEN (DK $6,000)

While Amari Cooper may be listed as the number one receiver for the Raiders, Crabtree saw the most targets last season, and is just as threatening out wide. The Raiders vs Titans game has the highest over/under of the week at 51 points. You will want to get some exposure to this game, and Crabtree is a perfect option. Not only is he cheaper than Cooper, but last season in their game vs the Titans, Crabtree had 8 catches, 102 yards, for 21.1 DraftKings points. Those are some big numbers for the 15th most expensive wide receiver this week. Crabtree had seven or more targets for the last eight weeks of the season, and against a team who had the 27th DVOA against the pass, it sets him up for a potentially big first week.

Sterling Shepard - NYG @ DAL (DK $4,100)

With both Odell Beckham Jr. and Brandon Marshall listed as questionable for the season opener, it leaves Shepard as a cheap receiving option. Now, there is still some uncertainty about the health and playing status of the mentioned receivers for the Giants, so be sure to check in on those before rosters lock. But if one or both of those players are out, Shepard is in a good spot to produce some points. The Cowboys do have a good defense against the pass, 8th DVOA, but the targets have to go somewhere for the Giants, and Shepard will be that man. He ended the season last year with 10 or more DraftKings points in three of their final four games, and really seemed to develop as a rookie. He finished with eight touchdowns, which was second highest on the team behind OBJ. Good amount of savings, with a potential for a bump in targets.

Antonio Brown - PIT @ CLE (DK $8,800)

If you are looking to spend up on wide receiver, look no further than Antonio Brown. He is a PPR machine, and playing on DraftKings, getting that full point is huge for your team. Brown is up against Cleveland, who last season, had the 29th DVOA vs the pass. They simply couldn't stop the passing game, which puts Brown in a great spot to really rack up some points. Brown averaged 21.5 DraftKings points per game, which was the best of all receivers. His price can make him tough to fit into some lineups, but his consistency and overall production, make him great in any format.

 

DraftKings DFS Tight Ends - Week 1 Picks

Delanie Walker - TEN vs OAK (DK $4,300)

Tight end is a spot where a lot of DFS players like to spend down, since the production can vary week to week, but Walker is nearly $2K cheaper than the most expensive option, and is in a good spot. He is up against the Raiders who had the 23rd DVOA vs tight ends last season. This game has the highest over/under of the week at 51 points, and with Walker being the second favorite target of Mariota last season, he is in a prime spot to score big.

Austin Hooper - ATL @ CHI (DK $3,00)

If you are truly looking to spend down at tight end, and almost a punt play, look at Hooper on Atlanta. He is listed as the number one tight end of the depth chart for the Falcons, so at least he will be on the field. The uncertainly comes from the fact he only had 22 receptions in 16 games last year. Not a huge part of the offense by any means, but is up against the Bears who had the 28th DVOA vs tight ends last year.

 

DraftKings DFS Defenses - Week 1 Picks

St. Louis Rams @ Indianapolis Colts (DK $3,200)

We all know that defense can be one of the more unpredictable plays in daily fantasy, and in searching for a team in a good spot, you will see the Rams as a top option. The Rams had the 15th overall DVOA last season, but the true upside for them comes from their match up vs the Colts. Without Andrew Luck at the helm for the Colts, they are going to be in rough shape on offense, which leaves the Rams the chance to capitalize. The Colts have the fourth lowest implied team total at 19 points, and we should see the Rams as a popular option.

 

More Week 1 Lineup Prep




REAL-TIME FANTASY NEWS

Max Domi

Out Indefinitely Due to Offseason Surgery Complications
Tanner Koziol

a Long-Shot Dynasty Tight End?
Dylan Cease

Heading to Injured List With Hamstring Injury
Kevin Coleman Jr.

in the Right Place for Opportunities
Josh Cameron

has Long-Term YAC Upside in Liam Coen's Offense
Rashee Rice

Chiefs Have No Plans to Sign Rashee Rice to Long-Term Extension
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Cole Payton

Dynasty Managers Will Have to be Patient with Cole Payton
Taylen Green

Does Taylen Green's Speed Get Him on the Dynasty Radar?
Jack Endries

Is Jack Endries the Tight End of the Future in Cincinnati?
CJ Daniels

a Developmental Stash in Dynasty Leagues
Garrett Nussmeier

a Low-Risk Target with Upside in Dynasty Leagues?
Jam Miller

Has Sneaky Value if He Can Earn a Roster Spot
Justice Hill

a Dynasty Drop Candidate Wherever He's Still Rostered
J'Mari Taylor

Is J'Mari Taylor Worth a Taxi-Squad Spot in Deep Dynasty Leagues?
Greg Dulcich

Has a Lack of Competition Made Greg Dulcich a Dynasty Sleeper?
Carson Beck

a Worthy Investment in the Later Rounds of Rookie Drafts
Devon Toews

Logs Two Assists In Game 3 Defeat
Brett Howden

Nets 10th Postseason Goal
Mitchell Marner

Delivers Two Assists in Comeback Victory
Mark Stone

Returns With Multi-Point Effort
Valeri Nichushkin

Exits Early Sunday
Nathan MacKinnon

Hurt in Game 3 Loss
Isaiah Hartenstein

Provides Steady Production in Defeat
Chet Holmgren

Has a Quiet Offensive Night on Sunday
Shai Gilgeous-Alexander

Held Under 20 Points in Game 4
Stephon Castle

Hands Out Six Assists in Game 4 Win
Devin Vassell

Tallies 13 Points in Game 4 Win
De'Aaron Fox

Records Double-Double as Spurs Even Series
Victor Wembanyama

Sets Tone Early as Spurs Force a Pivotal Game 5
Isaac Guerendo

Could be a Drop Candidate in Dynasty Leagues in 2026
Jayden Higgins

' Dynasty Arrow is Pointing Up With Clear Path to WR2 Role in Houston
Jakobi Meyers

a Sell-High Candidate in Dynasty Formats?
Drake Maye

to Make a Big Leap in 2026 in Second Season With Josh McDaniels?
Jamal Murray

Earns First Career All-NBA Selection
Kevin Durant

Becomes First Player to Make All-NBA Team With Five Franchises
Shai Gilgeous-Alexander

Victor Wembanyama Lead All-NBA First Team
Taylor Hall

Enjoying Life in Carolina
Mark Stone

Returns to Action Sunday
Cale Makar

Rejoins Avalanche Lineup Sunday
Cason Wallace

Joins Starting Unit Sunday
De'Aaron Fox

Doesn't "Feel Great" Entering Game 4
Jalen Williams

Won't Play Sunday
Christian Watson

Is Christian Watson on the Verge of a Legitimate Breakout?
Khalil Shakir

Dynasty Value in Decline
Travis Hunter

Still a Risky Buy, Even at his Sunken Dynasty Cost
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
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Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
Evan Mobley

Tallies Series-High 24 Points on Saturday
Donovan Mitchell

Struggles at the Line Saturday
Karl-Anthony Towns

Continues Playmaking Surge on Saturday
OG Anunoby

Delivers Clean Shooting Line Saturday
Mikal Bridges

Fills Box Score in Game 3 Win
Jalen Brunson

Pushes Knicks Closer to NBA Finals
Orlando Magic

Magic Interview Jeff Van Gundy for Head-Coaching Position
Phillip Danault

Extends Point Streak to Three Games
Josh Anderson

Nets Two Goals in Painful Loss
Jalen Chatfield

Delivers Two Assists in Crucial Win
Mark Jankowski

Contributes Two Assists in Game 2 Victory
Eric Robinson

Scores in Second Consecutive Game
Nikolaj Ehlers

Tallies Two Goals as Hurricanes Bounce Back Saturday
Giannis Antetokounmpo

Magic Reportedly Have Giannis Antetokounmpo on Their Radar
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Nazem Kadri

Contributes an Assist in Losing Effort
Ross Colton

Nets Lone Avalanche Goal Friday Night
Rasmus Andersson

Extends Assist Streak to Four Games
Pavel Dorofeyev

Focuses on Playmaking in Friday's Win
Jack Eichel

Enjoys Multi-Point Outing in Game 2 Win Friday
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Robby Snelling

Will Undergo Tommy John Surgery
Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
CFB

Lincoln Riley Believes USC is Ready for Playoff Run
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Notre Dame-Stanford Rivalry Renewed Through 2028
CFB

Ahmad Hardy Says He's "Back to the Road to Success"
CFB

Texas Tech Graduate Judge Recuses Himself from Brendan Sorsby Case
CFB

UCLA Tackle Jordan Davis Officially Eligible for 2026 Season
CFB

Bret Bielema Supports Significant College Football Playoff Expansion
Michael Thorbjornsen

Brings High Upside to CJ Cup Byron Nelson
Luke List

Carrying Poor Form Into CJ Cup Byron Nelson
Tom Kim

Hoping to Build on Strong Myrtle Beach Finish
PGA

Sungjae Im Brings Upside to TPC Craig Ranch
Billy Horschel

Looking for Turnaround at CJ Cup Byron Nelson
Adam Hadwin

Difficult to Trust at TPC Craig Ranch
Tony Finau

Looking for Consistency at TPC Craig Ranch
Luke Clanton

Searching for Form at CJ Cup Byron Nelson
Aaron Rai

Withdraws From CJ Cup Byron Nelson
Wyndham Clark

Can Wyndham Clark Find Form at CJ Cup?
Si Woo Kim

Looks To Stay Hot at CJ Cup
Scottie Scheffler

to Defend CJ Cup Byron Nelson Title This Week
Jordan Spieth

Looking For Victory at TPC Craig Ranch
PGA

Matti Schmid Looks to Keep Recent Momentum Going at TPC Craig Ranch
Brooks Koepka

a High-Upside Play at CJ Cup Byron Nelson
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF