X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

Cowboys vs. 49ers Betting Picks - Free NFL Best Bets, Odds, Predictions for the Divisional Round

Christian McCaffrey - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Free NFL betting picks, odds, predictions for the Cowboys vs. 49ers in the Divisional Round (2023). Our best bets and top NFL picks for moneylines, over/unders and more.

Welcome RotoBallers to our betting picks for the Dallas Cowboys vs. San Francisco 49ers, another article in our weekly series of free NFL betting picks for every game on the schedule. This free NFL betting breakdown article is for Sunday, January 22nd, 2022.

Attention fellow sports bettors! We have some exciting news to share as we are now partnered with various sportsbooks and have some sweet sports betting promo offers and freebies for you. Get your deposit bonus and also a year of free RotoBaller Premium access for all sports and all tools ($450 value), when you sign up with a new account today! After you're signed up, use our picks in this article for spreads, totals, and props to win big.

In addition to all of our other betting content and advice, we have now added weekly betting analysis articles and betting recommendations for each NFL game. Every single game on the NFL schedule will have its own betting analysis, betting breakdown and betting picks, every single week! We hope you enjoy, and good luck RotoBallers.

Be sure to check all of our fantasy baseball lineup tools and resources:

 

Today's Betting Overview - Cowboys @ 49ers

The Cowboys take on the 49ers on Sunday, January 22nd at Levi's Stadium, Santa Clara. RotoBaller provides free handicapping picks and odds for all NFL games throughout the 2022 season.

  • Matchup: Dallas Cowboys (12-5) vs. San Francisco 49ers (13-4)
  • Date: Sunday, January 22nd, 2022
  • Time: 6:30 PM ET
  • Venue: Levi's Stadium

 

Today's NFL Sportsbook Odds - Cowboys @ 49ers

If you are new to any of these sportsbooks, be sure to take advantage of the promo offers:

Featured Promo: Get any Betting Premium Pass for 50% off using code SMASH. Win more with exclusive betting picks from proven winners across 9 sports! Find optimal bets with our Betting Picks Tool and Bet Weighting Tool and follow along in our VIP chat rooms! Go Premium, Win More!

 

Dallas Cowboys - NFL Betting Analysis

In the Divisional Round, the Cowboys will look to keep things rolling after picking up a 31-14 over the Tampa Bay Buccaneers. Besides winning straight up, the Cowboys also came away with an ATS win as the -3.0 point favorite. With an over-under betting line of 45.5, the two teams fell below that figure as they combined for 45. On their way to picking up a 17-point win, Dallas held an 18-point lead heading into the 4th quarter at 24-6. Through 18 games, the Cowboys have an ATS record of 11-7. So far, they have an over-under record of 9-9. This week's betting total of 46.0 is right in line with their previous games.

As the Cowboys prepare to take on San Francisco, they have played well on offense, ranking 4th in points per game at 27.8. Against the 49ers, they will be facing the NFL's 1st ranked defense. Even though the Cowboys head into this week's game ranked 14th in pass yards per game and have a tough defensive matchup, we project them to have an above-average performance in the passing game. A key matchup to watch through the game is if Dallas will continue to run the ball well, averaging 134.8 yards per game on the ground.

 

San Francisco 49ers - NFL Betting Analysis

Last week, the 49ers picked up a Wild Card Weekend win as they took down the Seahawks by a score of 41-23. Besides winning straight up, the 49ers also came home with an ATS win as the -9.5 point favorites. The teams combined for a total of 64 points, which surpassed the over-under betting line of 42. On their way to picking up an 18 point win, San Francisco held a 6-point lead heading into the 4th quarter at 23-17. Through 18 games, the 49ers have an ATS record of 12-6. So far, they have an over-under record of 10-8. This week's betting total of 46.0 is slightly higher than the line in their previous games.

Heading into this week's matchup, the 49ers' offense is averaging 27.3 points per game, placing them 6th in the NFL. On the other side, they will be facing the 6th-ranked scoring defense. This week, look for the 49ers are facing a secondary ranked 10th in passer rating allowed. On the ground, the 49ers should be in line for a good performance, as they are one of the better-rushing team's in the league and are facing a defense that has its problem stopping the run.

 

Today's NFL Betting Pick - Cowboys vs. 49ers

Dallas comes into the game looking to continue their recent success over San Francisco, as they have won 2 of their last 3 matchups. The two teams have combined to average 54.7 points per game in their last 3 meetings. Last year, the Cowboys and 49ers did not play each other.

The Dallas Cowboys have performed well vs the spread in recent games, going 2-1. The Cowboys' offense has averaged 32.7 points per game over the 3 most recent meetings with San Francisco, compared to the 49ers at 22.0.

Spanning across their last 3 games, Dallas has gone 2-1. Their strong play has also resulted in a strong ATS mark of 2-1 (last 3).

In their last 3 road games, Dallas has averaged 21.3 points per game while allowing 17.7. The team's record in this stretch was 2-1 while going 2-1.

Over their last 3 regular season games, the 49ers have gone 3-0 straight up. The team has also been excellent vs the spread, going 2-1. Their over-under record in these games was 3-0

San Francisco has played well in their previous 3 home games, going 3-0 straight up. In this stretch, they averaged 38.67 points per game while allowing 18.7. The team also performed well vs the spread at 3-0.

Recommended ATS Betting Pick: 49ers -4.0

Recommended OU Betting Pick: Over 46.0



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Rashid Shaheed

Could Play Extensively in Seahawks Debut
Aaron Judge

Headlines AL Silver Slugger Award Winners
Terry McLaurin

Officially Ruled Out for Week 10
Kelly Olynyk

Cleared to Play on Friday
Jeremy Sochan

Available to Play Friday Against Houston
Puka Nacua

Will Play in Week 10
Steven Adams

Cleared to Face the Spurs
De'Andre Hunter

Available on Friday
Luke Kennard

Ruled Out Friday Against the Raptors
Kyshawn George

Ruled Out Versus Cleveland
William Eklund

Moved to Injured Reserve
Cam Thomas

Out 3-4 Weeks
Gustav Nyquist

Expected to Remain Out Friday
Luguentz Dort

Will Miss Friday's Meeting with Sacramento
Thatcher Demko

Questionable to Play This Weekend
Brock Purdy

Questionable Again, Won't Start in Week 10
Austin Reaves

Out Again on Saturday
Rasmus Dahlin

Takes Leave of Absence
Filip Hallander

to Miss at Least Three Months With Blood Clot
Domantas Sabonis

Will Not Play Friday vs. the Thunder
Kevin Bahl

a Game-Time Call Friday
Patrick Kane

Returns to Action Friday
Garrett Wilson

Listed as Questionable for Week 10, Expected to Play
Shohei Ohtani

Headlines List of NL Silver Slugger Winners
MLB

Munetaka Murakami Officially Being Posted on Friday
Alvin Kamara

Listed as Questionable for Week 10
De'Aaron Fox

To Make Season Debut On Saturday
Aaron Jones Sr.

Questionable for Week 10
Brian Thomas Jr.

Ruled Out For Week 10
D'Andre Swift

Listed as Questionable for Week 10
J.K. Dobbins

Getting Second Opinion on Foot Injury
Collin Sexton

Downgraded from Probable to Doubtful on Friday
LaMelo Ball

Downgraded to Doubtful on Friday
Kyler Murray

Expected to Return This Season
Yves Missi

Remains Sidelined on Saturday
Al Horford

Tagged as Questionable on Friday
Anthony Edwards

Available for Friday's NBA Cup Game
Harold Fannin Jr.

Questionable for Sunday
Justin Fields

Jets Refusing to Name Starting QB; Justin Fields Expected to Get the Nod
Luke Kennard

Considered Questionable on Friday
Shedeur Sanders

Back in QB2 Role in Week 10
Kayshon Boutte

Ruled Out in Week 10 Against Tampa
Kyshawn George

Downgraded to Questionable on Friday
Rhamondre Stevenson

Officially Ruled Out for Week 10
Tetairoa McMillan

Questionable to Play With Hamstring Injury
Rico Dowdle

Cleared to Play Against Saints
Harold Fannin Jr.

Back at Friday's Practice, on Track to Play Sunday?
DeForest Buckner

Placed on Injured Reserve With Neck Injury
Chris Godwin

Will be Ruled Out in Week 10
Jordan Poole

Out with Quad Strain
Nikola Jović

Nikola Jovic Available vs. Hornets
Norman Powell

Available vs. Hornets
Randy Brown

Set For UFC Vegas 111 Main Event
Gabriel Bonfim

Looks To Extend His Win Streak
Joseph Morales

A Favorite At UFC Vegas 111
Matt Schnell

Set For UFC Vegas 111 Co-Main Event
Uros Medic

Aims To Win Back-To-Back Fights
Muslim Salikhov

Looks For His Fourth Consecutive Win
Chris Padilla

Looks To Remain Unbeaten In The UFC
Chris Kreider

Extends Goal Streak to Four Games
Ismael Bonfim

Looks To Get Back In The Win Column
Nikita Kucherov

Lifts Lightning Past Golden Knights
Marco Tulio

Looks To Remain Undefeated In The UFC
Jalen Chatfield

Injured in Thursday's WIn
Christian Leroy Duncan

Set To Open Up UFC Vegas 111 Main Card
Dougie Hamilton

Exits Early Thursday
Anthony Cirelli

Expected to Be Fine for Saturday
Michael Misa

Sharks Place Michael Misa on Injured Reserve
Kyle Tucker

Headlines List of 13 Players to Receive Qualifying Offers
Pete Fairbanks

Becomes a Free Agent
Filip Hallander

Out Against Capitals
Tyson Kozak

Available Versus Blues
Cody Glass

Returns to Action Thursday
Connor Brown

Out on Thursday
Mats Zuccarello

Could Be an Option Friday
Matt Duchene

Remains Out Thursday
Roope Hintz

a Game-Time Call Thursday
CFB

Luke Fickell Will Return as Wisconsin's Head Coach in 2026
Bo Bichette

Blue Jays Extend Qualifying Offer to Bo Bichette
Craig Stammen

Named Padres New Manager
K'Andre Miller

Could Return to Action Thursday
Jorge Polanco

Declines his 2026 Option to Become a Free Agent
Chris Sale

Braves Picking Up Chris Sale's 2026 Option
Michael Thorbjornsen

Poised to Continue Hot Play in Mexico
Davis Riley

Struggling to Find Form Ahead of World Wide Technology Championship
Taylor Montgomery

Leaning on Putter at World Wide Technology Championship
Stephan Jaeger

Offers Strong Value at World Wide Technology Championship
Ben Griffin

Looks to Stay Hot at El Cardonal
Nick Dunlap

Looking to Find His Game at El Cardonal
Wyndham Clark

Searching for Consistency at El Cardonal
Michael Brennan

Aims to Extend Fairytale Start at El Cardonal
Shane Bieber

Staying in Toronto for 2026
Salvador Perez

Agrees to Two-Year Extension With Royals
Trevor Story

Opts in for Remaining Two Years on his Contract
Yu Darvish

to Miss All of 2026 Following Flexor-Tendon Surgery
Shota Imanaga

Becomes a Free Agent
Luis Robert Jr.

White Sox Pick Up 2026 Option on Luis Robert Jr.
CFB

LJ Martin Expected to Play in Top-10 Matchup Against Texas Tech
PGA

LIV Golf Expanding To 72-Hole Format In 2026
Atlanta Braves

Braves Hire Walt Weiss as Their Next Manager
Kris Bubic

Cleared to Begin a Throwing Program
Brandon Woodruff

Declines Mutual Option for 2026
Freddy Peralta

Brewers Exercise 2026 Option on Freddy Peralta
Lucas Giolito

Declines his 2026 Player Option
J.J. Spaun

Finishes Sixth at Procore Championship
PGA

Matti Schmid Finishes Tied for 46th at Baycurrent Classic
Keith Mitchell

Finishes Tied for 10th at Baycurrent Classic
Si Woo Kim

Finishes Tied for 21st at Genesis Championship
Mackenzie Hughes

Misses The Cut at Sanderson Farms Championship
Max Greyserman

Finishes Second at Baycurrent Classic
Austin Eckroat

Finishes Tied for 56th at Baycurrent Classic
Luke Clanton

Finishes Tied for 56th at Bank of Utah Championship
Pete Alonso

Officially Opts Out of his Contract With Mets
Kyle Larson

Wins His Second NASCAR Cup Series Championship at Phoenix
Ryan Blaney

Concludes the 2025 Season with A Win at Phoenix
William Byron

Strong Championship Effort Ends With Late-Race Flat-Tire Crash
Denny Hamlin

Overtime Four-Tire Call Costs Denny Hamlin the Championship
Chase Briscoe

Championship Bid Never Really Started After Two Tire Failures
Brad Keselowski

Nearly Steals Phoenix Race
David Onama

Suffers First-Round TKO Loss
Steve Garcia

Scores First-Round TKO Win
Ante Delija

Suffers His First UFC Loss
CFB

Dylan Raiola Suffers Season-Ending Injury
Waldo Cortes-Acosta

Gets Knockout Win
Themba Gorimbo

Drops Decision At UFC Vegas 110
Jeremiah Wells

Gets Back In The Win Column
Yadier del Valle

Remains Undefeated
Isaac Dulgarian

Cut By UFC Following Submission Loss
Daniel Frunza

Still Winless In The UFC
Charles Radtke

Dominates Daniel Frunza
Allan Nascimento

Gets Submission Win
Austin Cindric

is A Driver to Avoid for Phoenix DFS Lineups
Alex Bowman

Could Alex Bowman be A Sneaky Tournament Play for Phoenix?
Noah Gragson

Should DFS Players Roster Noah Gragson At Phoenix?
Erik Jones

Is Erik Jones Worth Rostering for DFS at Phoenix?
Michael McDowell

an Easy Recommendation for DFS at Phoenix

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP