👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


Cowboys vs. 49ers Betting Picks - Free NFL Best Bets, Odds, Predictions for the Divisional Round

Christian McCaffrey - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Free NFL betting picks, odds, predictions for the Cowboys vs. 49ers in the Divisional Round (2023). Our best bets and top NFL picks for moneylines, over/unders and more.

Welcome RotoBallers to our betting picks for the Dallas Cowboys vs. San Francisco 49ers, another article in our weekly series of free NFL betting picks for every game on the schedule. This free NFL betting breakdown article is for Sunday, January 22nd, 2022.

Attention fellow sports bettors! We have some exciting news to share as we are now partnered with various sportsbooks and have some sweet sports betting promo offers and freebies for you. Get your deposit bonus and also a year of free RotoBaller Premium access for all sports and all tools ($450 value), when you sign up with a new account today! After you're signed up, use our picks in this article for spreads, totals, and props to win big.

In addition to all of our other betting content and advice, we have now added weekly betting analysis articles and betting recommendations for each NFL game. Every single game on the NFL schedule will have its own betting analysis, betting breakdown and betting picks, every single week! We hope you enjoy, and good luck RotoBallers.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Today's Betting Overview - Cowboys @ 49ers

The Cowboys take on the 49ers on Sunday, January 22nd at Levi's Stadium, Santa Clara. RotoBaller provides free handicapping picks and odds for all NFL games throughout the 2022 season.

  • Matchup: Dallas Cowboys (12-5) vs. San Francisco 49ers (13-4)
  • Date: Sunday, January 22nd, 2022
  • Time: 6:30 PM ET
  • Venue: Levi's Stadium

 

Today's NFL Sportsbook Odds - Cowboys @ 49ers

If you are new to any of these sportsbooks, be sure to take advantage of the promo offers:

Featured Promo: Get any Betting Premium Pass for 50% off using code SPRING. Win more with exclusive betting picks from proven winners across 9 sports! Find optimal bets with our Betting Picks Tool and Bet Weighting Tool and follow along in our VIP chat rooms! Go Premium, Win More!

 

Dallas Cowboys - NFL Betting Analysis

In the Divisional Round, the Cowboys will look to keep things rolling after picking up a 31-14 over the Tampa Bay Buccaneers. Besides winning straight up, the Cowboys also came away with an ATS win as the -3.0 point favorite. With an over-under betting line of 45.5, the two teams fell below that figure as they combined for 45. On their way to picking up a 17-point win, Dallas held an 18-point lead heading into the 4th quarter at 24-6. Through 18 games, the Cowboys have an ATS record of 11-7. So far, they have an over-under record of 9-9. This week's betting total of 46.0 is right in line with their previous games.

As the Cowboys prepare to take on San Francisco, they have played well on offense, ranking 4th in points per game at 27.8. Against the 49ers, they will be facing the NFL's 1st ranked defense. Even though the Cowboys head into this week's game ranked 14th in pass yards per game and have a tough defensive matchup, we project them to have an above-average performance in the passing game. A key matchup to watch through the game is if Dallas will continue to run the ball well, averaging 134.8 yards per game on the ground.

 

San Francisco 49ers - NFL Betting Analysis

Last week, the 49ers picked up a Wild Card Weekend win as they took down the Seahawks by a score of 41-23. Besides winning straight up, the 49ers also came home with an ATS win as the -9.5 point favorites. The teams combined for a total of 64 points, which surpassed the over-under betting line of 42. On their way to picking up an 18 point win, San Francisco held a 6-point lead heading into the 4th quarter at 23-17. Through 18 games, the 49ers have an ATS record of 12-6. So far, they have an over-under record of 10-8. This week's betting total of 46.0 is slightly higher than the line in their previous games.

Heading into this week's matchup, the 49ers' offense is averaging 27.3 points per game, placing them 6th in the NFL. On the other side, they will be facing the 6th-ranked scoring defense. This week, look for the 49ers are facing a secondary ranked 10th in passer rating allowed. On the ground, the 49ers should be in line for a good performance, as they are one of the better-rushing team's in the league and are facing a defense that has its problem stopping the run.

 

Today's NFL Betting Pick - Cowboys vs. 49ers

Dallas comes into the game looking to continue their recent success over San Francisco, as they have won 2 of their last 3 matchups. The two teams have combined to average 54.7 points per game in their last 3 meetings. Last year, the Cowboys and 49ers did not play each other.

The Dallas Cowboys have performed well vs the spread in recent games, going 2-1. The Cowboys' offense has averaged 32.7 points per game over the 3 most recent meetings with San Francisco, compared to the 49ers at 22.0.

Spanning across their last 3 games, Dallas has gone 2-1. Their strong play has also resulted in a strong ATS mark of 2-1 (last 3).

In their last 3 road games, Dallas has averaged 21.3 points per game while allowing 17.7. The team's record in this stretch was 2-1 while going 2-1.

Over their last 3 regular season games, the 49ers have gone 3-0 straight up. The team has also been excellent vs the spread, going 2-1. Their over-under record in these games was 3-0

San Francisco has played well in their previous 3 home games, going 3-0 straight up. In this stretch, they averaged 38.67 points per game while allowing 18.7. The team also performed well vs the spread at 3-0.

Recommended ATS Betting Pick: 49ers -4.0

Recommended OU Betting Pick: Over 46.0



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Analysis




REAL-TIME FANTASY NEWS

Parker Washington

Set to Play "Most Important Role" of His Career in Jaguars Offense
Elly De La Cruz

Exits with Hamstring Tightness
Tyler Reddick

Is One of the Top Favorites to Win at Nashville
Kyle Larson

May Continue his Top-10 Consistency at Nashville this week
Christopher Bell

Is One of the Top Competitors for the Win at Nashville
Chase Briscoe

Is A Must Start for Nashville DFS Lineups
Chase Elliott

has Plenty of Upside for Nashville DFS Lineups
William Byron

Is William Byron A Playable DFS Option for Nashville Lineups?
Wan'Dale Robinson

Dynasty Value May Have Peaked in 2025
Carson Hocevar

Is Likely to have Another Solid Result at Nashville
Tyler Shough

Should Dynasty Managers Consider Selling High on Tyler Shough?
NASCAR

Should Fantasy Players Roster Bubba Wallace at Nashville?
Garrett Wilson

Dynasty Upside Remains High Despite Questionable Offensive Environment in New York
Chris Buescher

Is A Decent All-Around DFS Option for Nashville Lineups
Daniel Suarez

is Likely to Drop Positions during the Cracker Barrel 400
Kenneth Gainwell

Carries Dynasty Sell-High Appeal After Breakout 2025 Campaign
Emeka Egbuka

Undervalued in Dynasty Formats After Underwhelming Close to 2025?
Trey Benson

a Dynasty Hold Despite Unfavorable Situation
Omar Cooper Jr.

a Long-Term Investment in the First Round of Rookie Drafts
Colston Loveland

Just How High is Colston Loveland's Dynasty Ceiling?
Garrett Crochet

Suffers Setback, Likely to Undergo MRI for Lat Tightness
Zay Flowers

A New-Look Offense in Baltimore Could Impact Zay Flowers' Dynasty Value
LeQuint Allen Jr.

a Dynasty Dart Throw with a Potential Path to Upside
Denny Hamlin

Could Denny Hamlin Dominate at Nashville?
Ryan Blaney

Is a DFS Tournament Option at Nashville
Ty Gibbs

Don't Overlook Ty Gibbs at Nashville
Joey Logano

Could Show Life at Nashville
Ross Chastain

Needs a Good Run at Nashville
Shedeur Sanders

Falling Behind in Quarterback Competition?
Isaiah Davis

Is Isaiah Davis the More Valuable Jets Handcuff?
Trey McBride

a Coveted Dynasty Cornerstone
Chet Holmgren

Fails to Step Up in the Season Finale
Brock Purdy

Still Not Valued as a Dynasty QB1
Cason Wallace

Ends Postseason with Strong Showing
Shai Gilgeous-Alexander

Caps MVP Season with Game 7 Exit
Justin Jefferson

an Obvious Bounce-Back Candidate
Stephon Castle

Continues Postseason Run with 16 Points
Julian Champagnie

Shines in Series-Clinching Win
De'Aaron Fox

Provides Secondary Punch in Game 7 Triumph
Victor Wembanyama

Earns Conference Finals MVP in Spurs' Game 7 Win
J.J. McCarthy

Holding J.J. McCarthy in Dynasty Leagues Will Require Patience
Harold Fannin Jr.

Does Harold Fannin Jr. Have Top-Three Upside in Dynasty Leagues?
Jaylen Waddle

the Top Receiver to Roster in Denver?
Josh Downs

Climbing Up the Dynasty Rankings with Bigger Role Ahead?
Jalen McMillan

Has Been 'Slightly Better' Than Teammate During OTAs
NBA

Warriors Prioritize Depth Around Returning Steve Kerr
Donovan Mitchell

Remains Cleveland's Top Priority
Adou Thiero

Remains a Lakers Development Project
NBA

76ers Hire Mike Gansey as President of Basketball Operations
NBA

Chicago Bulls Explore Kevin Young as Coaching Candidate
Kyrie Irving

Reports He's Nearing Full Strength in ACL Recovery
Lane Hutson

Posts a Power-Play Assist in Game 5 Loss
Cole Caufield

Nets a Power-Play Goal in Season-Ending Loss
Seth Jarvis

Closes Out East Finals With Multi-Point Game
Logan Stankoven

Notches Three Points in Big Game 5 Win
Taylor Hall

Racks Up Three Points in Series-Clinching Win
Frederik Andersen

Remains Stellar as Hurricanes Clinch Finals Berth
Jacob Gonzalez

is Heading to the Big Leagues
Munetaka Murakami

Exits with Hamstring Tightness
Mitchell Robinson

Plans to Play in Game 1 After Finger Surgery
Ajay Mitchell

Ruled Out for Game 7
Jalen Williams

Unavailable in Decisive Game 7
NBA

Magic Finalizing Hire of Sean Sweeney as Head Coach
Eury Pérez

Eury Perez is Placed on 15-Day Injured List
Deiveson Figueiredo

Set For UFC Macau Main Event
MMA

Yadong Song Returns At UFC Macau
Alonzo Menifield

An Underdog At UFC Macau
Zhang Mingyang

Set For UFC Macau Co-Main Event
Tallison Teixeira

Looks To Win Back-To-Back Fights
Sergei Pavlovich

A Favorite At UFC Macau
Cameron Smotherman

Looks To Bounce Back
Kai Asakura

Looks To Get Back In The Win Column
CFB

Faizon Brandon In Position to Start Week 1
CFB

Dane Weber Commits to Cal
CFB

Joey McGuire Attempts to Add Texas to Schedule
CFB

Mike Leach on 2027 College Football Hall of Fame Ballot
CFB

Maryland, Baylor Schedule Home-and-Home
CFB

Taron Dickens Decommits From North Carolina
Jalen Williams

Limited in Game 6 Return
Jared McCain

Provides Bench Spark in Game 6 Loss
Shai Gilgeous-Alexander

Posts Lowest-Scoring Night of His MVP Season
De'Aaron Fox

Struggles From the Field Thursday
MLB

MLB Proposes Hard Salary Cap as Part of Next CBA
Kenley Jansen

Tigers Place Kenley Jansen on Injured List With Pelvic Inflammation
Teoscar Hernández

Teoscar Hernandez Heading to Injured List With Hamstring Strain
MON

Lane Hutson Struggles in Game 4 Loss
CAR

Logan Stankoven Nets Eighth Postseason Goal
CAR

Sebastian Aho Pots Game-Winner on Power Play
CAR

Nikolaj Ehlers Tallies Two Helpers in Impressive Road Win
CAR

Shayne Gostisbehere Records Two Assists in Game 4 Win
CAR

Frederik Andersen Establishes Hurricanes New Postseason Shutout Record
Yordan Alvarez

Continues Homer Barrage With Two More Long Balls on Wednesday
Cristopher Sánchez

Cristopher Sanchez Makes History With Seven More Shutout Innings Against Padres
Teoscar Hernández

Teoscar Hernandez Lifted From Wednesday's Game Early With Hamstring Strain
Kenley Jansen

Exits Relief Appearance on Wednesday With Groin Injury
Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
CFB

Drew Mestemaker a Top Big 12 Quarterback Right Away?
PGA

Sungjae Im Remains Boom-or-Bust at Colonial
PGA

Michael Thorbjornsen Trending in Wrong Direction Entering Colonial
Russell Henley

a Top Option at Colonial
Harry Hall

Hoping Putter Carries Him at Colonial
Rickie Fowler

Looks to Regain Momentum at Colonial
Pierceson Coody

Looking to Stay Hot at Colonial
Martin Necas

Collects an Assist in Game 4 Loss to Golden Knights
Gabriel Landeskog

Scores Only Avalanche Goal in Season-Ending Loss
Carter Hart

Finishes Series-Clincher With 20 Saves
Dylan Coghlan

Continues Unlikely Success Story
Cole Smith

Scores Series-Clincher Tuesday Night
Mark Stone

Nets Another Goal as Golden Knights Finish Off Avalanche
Ludvig Aberg

Looking to Exchange Momentum for a Victory in Fort Worth
Stephan Jaeger

Trending Upward as PGA Heads to Fort Worth
Max Homa

Comes Off Awful Putting Performance at PGA Championship
Tony Finau

Faces Different Test at the Colonial
Robert MacIntyre

Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Claude Giroux

Planning to Return for 20th NHL Campaign
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF