X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

Cowboys vs. 49ers Betting Picks - Free NFL Best Bets, Odds, Predictions for the Divisional Round

Christian McCaffrey - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Free NFL betting picks, odds, predictions for the Cowboys vs. 49ers in the Divisional Round (2023). Our best bets and top NFL picks for moneylines, over/unders and more.

Welcome RotoBallers to our betting picks for the Dallas Cowboys vs. San Francisco 49ers, another article in our weekly series of free NFL betting picks for every game on the schedule. This free NFL betting breakdown article is for Sunday, January 22nd, 2022.

Attention fellow sports bettors! We have some exciting news to share as we are now partnered with various sportsbooks and have some sweet sports betting promo offers and freebies for you. Get your deposit bonus and also a year of free RotoBaller Premium access for all sports and all tools ($450 value), when you sign up with a new account today! After you're signed up, use our picks in this article for spreads, totals, and props to win big.

In addition to all of our other betting content and advice, we have now added weekly betting analysis articles and betting recommendations for each NFL game. Every single game on the NFL schedule will have its own betting analysis, betting breakdown and betting picks, every single week! We hope you enjoy, and good luck RotoBallers.

Be sure to check all of our fantasy football rankings for 2025:

 

Today's Betting Overview - Cowboys @ 49ers

The Cowboys take on the 49ers on Sunday, January 22nd at Levi's Stadium, Santa Clara. RotoBaller provides free handicapping picks and odds for all NFL games throughout the 2022 season.

  • Matchup: Dallas Cowboys (12-5) vs. San Francisco 49ers (13-4)
  • Date: Sunday, January 22nd, 2022
  • Time: 6:30 PM ET
  • Venue: Levi's Stadium

 

Today's NFL Sportsbook Odds - Cowboys @ 49ers

If you are new to any of these sportsbooks, be sure to take advantage of the promo offers:

Featured Promo: Get any Betting Premium Pass for 30% off using code WIN. Win more with exclusive betting picks from proven winners across 9 sports! Find optimal bets with our Betting Picks Tool and Bet Weighting Tool and follow along in our VIP chat rooms! Go Premium, Win More!

 

Dallas Cowboys - NFL Betting Analysis

In the Divisional Round, the Cowboys will look to keep things rolling after picking up a 31-14 over the Tampa Bay Buccaneers. Besides winning straight up, the Cowboys also came away with an ATS win as the -3.0 point favorite. With an over-under betting line of 45.5, the two teams fell below that figure as they combined for 45. On their way to picking up a 17-point win, Dallas held an 18-point lead heading into the 4th quarter at 24-6. Through 18 games, the Cowboys have an ATS record of 11-7. So far, they have an over-under record of 9-9. This week's betting total of 46.0 is right in line with their previous games.

As the Cowboys prepare to take on San Francisco, they have played well on offense, ranking 4th in points per game at 27.8. Against the 49ers, they will be facing the NFL's 1st ranked defense. Even though the Cowboys head into this week's game ranked 14th in pass yards per game and have a tough defensive matchup, we project them to have an above-average performance in the passing game. A key matchup to watch through the game is if Dallas will continue to run the ball well, averaging 134.8 yards per game on the ground.

 

San Francisco 49ers - NFL Betting Analysis

Last week, the 49ers picked up a Wild Card Weekend win as they took down the Seahawks by a score of 41-23. Besides winning straight up, the 49ers also came home with an ATS win as the -9.5 point favorites. The teams combined for a total of 64 points, which surpassed the over-under betting line of 42. On their way to picking up an 18 point win, San Francisco held a 6-point lead heading into the 4th quarter at 23-17. Through 18 games, the 49ers have an ATS record of 12-6. So far, they have an over-under record of 10-8. This week's betting total of 46.0 is slightly higher than the line in their previous games.

Heading into this week's matchup, the 49ers' offense is averaging 27.3 points per game, placing them 6th in the NFL. On the other side, they will be facing the 6th-ranked scoring defense. This week, look for the 49ers are facing a secondary ranked 10th in passer rating allowed. On the ground, the 49ers should be in line for a good performance, as they are one of the better-rushing team's in the league and are facing a defense that has its problem stopping the run.

 

Today's NFL Betting Pick - Cowboys vs. 49ers

Dallas comes into the game looking to continue their recent success over San Francisco, as they have won 2 of their last 3 matchups. The two teams have combined to average 54.7 points per game in their last 3 meetings. Last year, the Cowboys and 49ers did not play each other.

The Dallas Cowboys have performed well vs the spread in recent games, going 2-1. The Cowboys' offense has averaged 32.7 points per game over the 3 most recent meetings with San Francisco, compared to the 49ers at 22.0.

Spanning across their last 3 games, Dallas has gone 2-1. Their strong play has also resulted in a strong ATS mark of 2-1 (last 3).

In their last 3 road games, Dallas has averaged 21.3 points per game while allowing 17.7. The team's record in this stretch was 2-1 while going 2-1.

Over their last 3 regular season games, the 49ers have gone 3-0 straight up. The team has also been excellent vs the spread, going 2-1. Their over-under record in these games was 3-0

San Francisco has played well in their previous 3 home games, going 3-0 straight up. In this stretch, they averaged 38.67 points per game while allowing 18.7. The team also performed well vs the spread at 3-0.

Recommended ATS Betting Pick: 49ers -4.0

Recommended OU Betting Pick: Over 46.0



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

NBA

Tosan Evbuomwan Joins Knicks
NBA

Kai Jones Links Up With EuroLeague Team
NBA

Bismack Biyombo Returns to Spurs
NBA

Bones Hyland Rejoins Timberwolves
Kobe Bufkin

Moves to Brooklyn
Trey Yesavage

Sets Franchise Strikeout Record On Monday
Yordan Alvarez

To Receive MRI For Sprained Left Ankle On Tuesday
Willson Contreras

Exits Early Monday With Right-Biceps Tightness
Yordan Alvarez

Exits With Ankle Sprain
Brock Bowers

Officially Active on Monday Night
Jauan Jennings

Day-to-Day With Ankle Injury
Logan O'Hoppe

Activated Off Seven-Day Injured List
CBJ

Denton Mateychuk Dealing With Groin Issue
Bo Horvat

Fine for Training Camp
Kirby Dach

on Track to Be Ready for Opening Night
Jose Altuve

Returns Against Rangers
J.J. McCarthy

Expected to Miss 2-4 Weeks With High-Ankle Sprain
J.J. McCarthy

Likely Out for Week 3 With High-Ankle Sprain
Jean Silva

Gets Finished For The First Time In His Career
Aaron Jones Sr.

Unlikely to Play in Week 3 Due to Hamstring Injury
Diego Lopes

Returns To The Win Column
Jayden Daniels

' Week 3 Status in Doubt
Rob Font

Outclassed In The Noche UFC 3 Co-Main Event
David Martinez

Wins His Second UFC Fight
Jared Gordon

Suffers Brutal TKO Loss At Noche UFC 3
Rafa Garcia

Wins Back-To-Back Fights
Brian Thomas Jr.

Dealing with Wrist Injury
Dustin Stoltzfus

Drops A Decision At Noche UFC 3
Kelvin Gastelum

Gets Back In The Win Column
Diego Ferreira

Suffers Second-Round TKO
Alexander Hernandez

Extends His Win Streak With A Brutal TKO
Quang Le

Suffers First-Round Knockout
Santiago Luna

Shines In His UFC Debut
Christopher Bell

Earns his First Bristol Cup Series Victory
Alex Bowman

Falls Short of Advancing Through Cup Series Playoffs
Chase Briscoe

Collects his Third Top-10 Finish at Bristol
Ryan Blaney

Strong Top-Five Bristol Performance Advances him to the Playoffs
Corey Heim

Earns his First Career Cup Series Top-10 Finish at Bristol
Giannis Antetokounmpo

Leads Greece to Bronze Medal
Alperen Sengün

Alperen Sengun Drops 28 Points in EuroBasket Finals
CFB

Indiana's Lee Beebe Jr. Out for Season with Knee Injury
Dennis Schröder

Dennis Schroder Named EuroBasket MVP
Bryce Eldridge

Giants to Promote Bryce Eldridge
Jaren Jackson Jr.

Progressing in Recovery
Jonathan Kuminga

Receives New Offer From Warriors
Kenneth Walker III

Bounces Back with Big Week 2 Performance
Bijan Robinson

Rushes for 143 Yards in Week 2
Justin Fields

Currently in Concussion Protocol
Cincinnati Bengals

Bengals Calling Around to Available Free-Agent Quarterbacks
Joe Burrow

to Undergo Surgery, Out at Least Three Months
Emil Heineman

Aiming to Take the "Next Step" This Season
Braeden Cootes

Good to Go for Camp
Ivan Fedotov

Blue Jackets Acquire Ivan Fedotov From Flyers
Aaron Jones Sr.

Injures Hamstring During Sunday Night Football
Darren Waller

Not Expected to Play in Week 3
Garrett Crochet

Punches Out 12 in Win
Cole Ragans

to Return on Wednesday
Jameson Williams

Records Long Touchdown in Week 2, Still Limited to Downfield Role?
George Kirby

Strikes Out 14 in Win
Jayden Daniels

Considered "Day-to-Day" with Knee Injury
Carlos Estévez

Carlos Estevez Exits with Back Tightness
Jonathan Taylor

Tops 200 Yards From Scrimmage in Week 2 Win
Joe Burrow

Could Miss Three Months if he Requires Toe Surgery
Davante Adams

Headlines Rams Receiving Corps Sunday
Wan'Dale Robinson

Explodes for 142 Yards, Touchdown in Overtime Thriller
Joe Flacco

Browns Not Considering Benching Joe Flacco After Week 2
Quentin Grimes

Still Not Close to a New Contract Agreement
Joel Embiid

"Looking Slender, Spry and in Positive Spirits"
Ty Gibbs

Has Arguably his Best Career Drive, but Only Finishes 10th
Chase Elliott

Despite Crashing Out at Bristol, Chase Elliott Advances to Round of 12
Austin Dillon

Misses Round of 12 After Extremely Mediocre Bristol Run
Shane Van Gisbergen

Shane van Gisbergen Fails to Advance to Round of 12
Josh Berry

Finishes Last in All Three Round of 16 Races to Fail to Advance
Luis Arraez

Takes a Seat on Sunday With Head Injury
Adolis García

Adolis Garcia Activated, Starting on Sunday
CFB

Ryan Williams Explodes In Return To Field
CFB

Drew Allar Plays Mediocre Game In Blowout Win
CFB

LaNorris Sellers Exits Game In Blowout Loss
CFB

DJ Lagway Tosses Five Interceptions In Loss
CFB

Garrett Nussmeier Plays Game Manager in Saturday's Win
CFB

CJ Carr Remains Poised In Narrow Loss
CFB

John Mateer Leads Oklahoma In Rout
CFB

Arch Manning Struggles Against UTEP
CFB

Jeremiah Smith Impresses In Win
Bryan Woo

Records Career-High 13 Strikeouts
Max Muncy

Exits Early on Saturday
CFB

Sam Leavitt Shines As Arizona State Rebounds From Week 2 Loss
Salvador Perez

Reaches 300 Home Runs, 1,000 RBI
Jose Altuve

Exits Early With Foot Discomfort
Trey Yesavage

Heading to Big Leagues
Will Smith

Placed on 10-Day Injured List
Ivan Demidov

Turning Heads in Rookie Camp
NHL

Calvin de Haan Signs With Swedish Team
Samuel Girard

Skates With Non-Contact Jersey
Mackenzie Blackwood

Dealing With Injury Ahead of Training Camp
Spencer Knight

Signs Three-Year Extension With Blackhawks
Chris Buescher

May have Another Solid Run at Bristol
Corey Perry

Out 6-8 Weeks Following Surgery
Kyle Busch

Should DFS Managers Roster Kyle Busch at Bristol?
Ricky Stenhouse Jr

Is Ricky Stenhouse Jr. Too Risky to Consider Rostering at Bristol?
Michael McDowell

Could be A Solid Value Option For Bristol DFS Lineups
Chase Elliott

Probably Won't Factor in for Bristol Win
NASCAR

Bubba Wallace Not as Strong at Bristol as Other Short Tracks
Alex Bowman

Needs to Win to Make Round of 12
Ross Chastain

has Never Led at Bristol but Has Been Pretty Consistent
Austin Dillon

Richmond Speed Unlikely to Carry Over to Bristol
Josh Berry

Might Run Well at Bristol, but Almost Certainly Won't Win to Advance
Justin Haley

Bristol One of Justin Haley's Few Recent Bright Spots
Tarik Skubal

Avoids Serious Injury, Expected to Make Next Start
CFB

Austin Simmons Listed As Game-Time Decision Against Arkansas
CFB

Nico Iamaleava Struggles In Fourth Straight Loss
Ukko-Pekka Luukkonen

Dealing With a "Tweak"
BUF

Alexandar Georgiev Joins Sabres on One-Year Deal
Corey Perry

Injured During Pre-Camp Skate
Tanner Bibee

Fans 10 in Two-Hit Shutout
CFB

Antonio Williams Out Against Georgia Tech
CFB

CJ Bailey Flashes Again in Win Over Wake Forest
CFB

Jaxson Moi a Game-Time Decision for Tennessee on Saturday
Jean Silva

A Favorite At Noche UFC 3
Diego Lopes

Set For Noche UFC 3 Main Event
Rob Font

Looks For His Third Consecutive Win
David Martinez

Set For Noche UFC 3 Co-Main Event
Rafa Garcia

An Underdog At Noche UFC 3
Jared Gordon

Looks To Win Back-To-Back Fights
Dustin Stoltzfus

Looks To Return To The Win Column
Kelvin Gastelum

In Dire Need Of Victory
Diego Ferreira

Looks To Get Back In The Win Column
Malcolm Brogdon

Heading to Knicks on One-Year Deal
CFB

David Sanders Jr. Won't Play Against Georgia
Landry Shamet

Staying with the Knicks
CFB

Dylan Edwards Slated to Return on Friday
Adam Lowry

Aims for Early-Season Return
CFB

Ryan Williams Expected to Play Against Wisconsin
CFB

Billy Edwards Jr. Unlikely to Play on Saturday
P.J. Washington

Officially Signs Contract Extension
CFB

David Sanders Jr. Questionable to Make Debut Against Georgia
Lauri Markkanen

Big at Both Ends as Finland Books Place in EuroBasket Semis
Luka Dončić

Luka Doncic Notches 39 Points in Losing Effort
NBA

Cam Reddish Expected to Move to Europe
NBA

Trey Lyles Joins Real Madrid
Charles Bassey

Signs Exhibit 10 Deal With Hawks
Sacramento Kings

Terence Davis Waived by Kings
Matthew Knies

Ready for Bigger Role With Maple Leafs
Jack Eichel

Unbothered by Lack of Extension
Sidney Crosby

Not Thinking About Leaving Pittsburgh
SJ

Michael Misa Signs Entry-Level Contract With Sharks
Rutger McGroarty

Nursing an Injury
Cameron Champ

the Ultimate Wild Card at Procore
Cameron Young

Looks to Extend Momentum in Napa
Davis Thompson

Searching for a Spark at Procore
Sahith Theegala

Looking to Reignite Form at Procore
Mackenzie Hughes

Aims for Another Strong Showing at Procore
Luke Clanton

Brings Ball-Striking Upside to Napa
Seamus Power

Looking to Overcome Poor Course History at Procore
Joe Highsmith

Hoping to Find Form in Napa

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP