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DraftKings Daily Fantasy Football Lineup Picks (Week 12 - Thanksgiving Day): NFL DFS Advice

Jason Bales' week 12 DraftKings lineup picks for Thanksgiving Day. Daily fantasy football sleepers, value picks and lineups advice for DraftKings DFS games and tournaments.

Welcome to RotoBaller's Daily Fantasy football DraftKings lineup picks for Week 12 (Thanksgiving only) of the NFL season. In this article, I, Jason Bales, will be taking you, the reader, through the best DraftKings DFS plays of the week for this upcoming Sunday.

These DraftKings lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. There are still quite a few great value plays available, so read on to find out which players are the best for Week 11. Good luck with your DraftKings DFS lineups!

Editor's Note: If you like DraftKings, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces, make a $20 deposit, and enter any game will receive our full season NFL (or NBA) Premium Pass for free, a $59.99 value. Just email [email protected] with your new FantasyAces username - and boom, that's it! We will email you with your Premium pass.

Be sure to check all of our fantasy football rankings for 2025:

 

DraftKings Quarterbacks - Week 12 - Thanksgiving Day DFS Picks

Kirk Cousins (at DAL, $5,900) 

Kirk Cousins is a great option at the quarterback position this Thanksgiving. There are only three games, so the quarterbacks are very limited. Cousins posted over 30 fantasy points in his last game, which was against the Green Bay Packers. He threw three touchdowns and 375 yards on only 30 pass attempts. This week, Cousins will have to bring his 'A' game, as the Dallas Cowboys are a very tough opponent. He should throw the ball around 40 times, as the Washington Redskins attempt to pick up a big win.

 

DraftKings Running Backs - Week 12 - Thanksgiving Day DFS Picks

Le'Veon Bell (at IND, $9,000)

Le'Veon Bell is the best fantasy running back in the league, especially now that he is playing wide receiver half of the game. He has over 34 fantasy points in two straight games now, and this Thanksgiving, he gets a great matchup against the Indianapolis Colts. The Colts are horrible defensively, and the Steelers should have little issue scoring early and often. In his last game, Bell was targeted nine times in the air and ran for just under 150 yards and a touchdown on the ground.

Rob Kelley (at DAL, $4,300) 

Rob Kelley is now starting for the Washington Redskins. Anyone that watched the Redskins' running back situation closely this season could have predicted this. Kelley looked great every time he touched the ball this season, and now it all paid off. He ran for over 125 yards and scored three touchdowns against the Green Bay Packers last week. He gets a tougher defense this Thanksgiving, but his price tag is low enough to roster him in all leagues.

 

DraftKings Wide Receivers - Week 12 - Thanksgiving Day DFS Picks

Antonio Brown (at IND, $9,200)

Antonio Brown is a little bit more expensive than Le'Veon Bell, and he is worth every single penny. Ben Rothelisberger was out for a couple of games with an injury, but he is back, and Brown is thankful for that this Thanksgiving. Against the Dallas Cowboys, he posted over 35 fantasy points on 18 targets. He had over 150 receiving yards and a touchdown. He has not been finding the end zone as frequently as he should, but that is liable to change any week with the amount of targets he is getting. Use him in all leagues.

Pierre Garcon (at DAL, $3,900) 

Pierre Garcon is finally starting to get involved in the Washington Redskins' offense. In the last two weeks, he has 17 targets and 12 receptions for just under 200 yards and a touchdown. The Dallas Cowboys are not great defensively against the passing attack, and Cousins will be looking toward Garcon more frequently now. His price tag is very low, so he makes for a great tournament flier this week.

 

DraftKings Tight Ends - Week 12 - Thanksgiving Day DFS Picks

Jason Witten (vs WAS, $3,200) 

Dak Prescott is looking toward Jason Witten on a very reliable basis now. In the last three weeks, he has seven or more targets in every game. He gets a good matchup this week against the Washington Redskins' mediocre defense, and his price tag is down. Obviously, Jordan Reed is the best tight end on the board, but if a cheaper option is needed, Witten could do wonders for tournament lineups.

 

DraftKings Defenses - Week 12 - Thanksgiving Day DFS Picks

Minnesota Vikings Defense (at DET, $3,400)

The Minnesota Vikings score touchdowns on the defensive end of the ball more than any team in the league. The Detroit Lions are expected to win this game, and Matthew Stafford has been good this season, but with limited options and expected high-scoring affairs, the Vikings are the best defense on the board. Use them in all leagues.




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REAL-TIME FANTASY NEWS

Francisco Alvarez

Needs Thumb Surgery, May Play Through Injury
Willy Adames

Out With Side Soreness on Tuesday
A.J. Brown

on Track to Play in Week 1
Jacob deGrom

Being Skipped in Rotation Due to Shoulder Fatigue
Adley Rutschman

Scratched on Tuesday With Abdominal Discomfort
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Brendan Smith Joins Blue Jackets on Tryout Deal
STL

Milan Lucic Joins Blues for Tryout
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Red Wings Pick Up Travis Hamonic
Austin Riley

Doesn't Appear Ready to Return Any Time Soon
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Unikely to Throw Normally Again This Year
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Could be Out Through Week 9 Bye
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Pacers Coach Rick Carlisle Agrees to a Multiyear Contract Extension on Tuesday
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Named as Colts Starting Quarterback
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Will Not Be Ready for Season Opener
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Likely to Start Season Without Contract Extension
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Hopes to Bounce Back in 2025-26
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Ready to Go for New Season
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Luka Doncic Cleared to Play on Tuesday Night
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Pulled With Hamstring Tightness
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Game 2 of Brewers-Cubs on Monday Postponed
Bryce Miller

to be Activated on Tuesday
Kyle Tucker

to Get Multiple Days Off
Shane Bieber

to Make Season Debut on Friday
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Could Start Season on NFI List
Zack Wheeler

has Surgery to Remove Blood Clot
De'Von Achane

Unlikely to Practice This Week
Justin Jefferson

Returning to Practice
Chris Godwin

Bucs Chris Godwin Likely to Start Season on PUP List
Joe Flacco

Browns Name Joe Flacco as Their Week 1 Starter
Jalen McDaniels

Inks Deal With New Orleans
N'Faly Dante

Signs Deal With Hawks
Matthew Stafford

Practicing on Monday
Dru Smith

Agrees to Deal With Heat
Austin Dillon

Scores an Upset Victory at Richmond
William Byron

Clinches the Regular Season Championship Title at Richmond
Denny Hamlin

Pit-Road Struggles Impede Denny Hamlin's Chances of a Top Finish at Richmond
Joey Logano

Earns A Fourth-Place Finish at Richmond
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Rallies to A Top-10 Finish at Richmond
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Dricus Du Plessis

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Aaron Pico

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Lerone Murphy

Scores Stunning First-Round Knockout
Leodalis De Vries

Earns Promotion to Double-A
Nathaniel Lowe

Finalizing Deal with Boston
Geoff Neal

Suffers First-Round Knockout Loss
Ketel Marte

Arizona Could Trade Ketel Marte in the Offseason
Carlos Prates

Gets Back In The Win Column
Michael Page

Dominates At UFC 319
Jared Cannonier

Gets Outclassed
Tim Elliott

Gets Submission Win
Kai Asakura

Still Winless In The UFC
Austin Cindric

has Arguably his Best Run of the Season at Richmond
Ryan Blaney

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Alex Bowman

Finishes Second but Loses Ground in Playoffs
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Chris Buescher

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Coby White

Bulls Not Interested in Trading Coby White
Dereck Lively II

Expected to be Ready for Camp
Brian Robinson Jr.

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John Metchie III

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Victor Scott II

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Trey Hendrickson

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Marcelo Mayer

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Christopher Bell

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Ryan Blaney

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Joey Logano

Will Start Last at Richmond After Practice Trouble
Chase Elliott

Lack of Top-Line Speed Hurts his DFS Potential
Kyle Larson

Recent String of Crashes Make Him a Big Risk at Richmond
William Byron

Probably Slightly Too Inconsistent at Richmond to Start for DFS
Ryan Preece

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Brad Keselowski

Probably the Best RFK Racing DFS Option at Richmond
Chase Briscoe

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Chris Buescher

a Solid Choice for DFS Play, but Teammates Look Faster
Terry McLaurin

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Rashee Rice

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Haywood Highsmith

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Amir Coffey

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Dricus Du Plessis

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Mikael Pyyhtia Re-Signs With Blue Jackets for One Year
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Tyson Foerster

on Track to Be Healthy for Season Opener
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Rockets Not Interested in Keeping Kevin Durant with Max Extension
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Isaiah Mobley Joins Turkish Team
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