October 4, 2025

Tennessee Titans running back Tyjae Spears (ankle) could be an intriguing flex option for fantasy managers in Week 5, but only if he's activated from Injured Reserve. Spears is currently listed as questionable after logging a limited practice as the team mulls whether he's ready to rejoin the 53-man roster. He missed the first four weeks of the season while recovering from an ankle injury, but the Titans' offense looks like the worst in the NFL and could desperately use a burst of energy. Spears offers exactly that. As a rookie in 2023, we saw him command 70 targets in the passing game while maintaining 4.53 yards per carry on 100 carries. He was headed for similar numbers last year if not for missing five games due to injury. Now, he has yet another chance to carve out a role on the ground and through the air. Starter Tony Pollard has been nothing special so far, and while he'd likely continue to be the lead back for at least a little while, Spears could actually have more fantasy value due to his burst and pass-catching upside. Week 5 is a perfect opportunity for the 24-year-old to contribute as the Titans face the Arizona Cardinals, who have allowed the sixth-most targets and 12th-most fantasy points to running backs in 2025. If he suits up Sunday, Spears has the potential to be a strong flex option, especially in PPR leagues.--Andersen Pickard
Source: RotoBaller