Happy Saturday, RotoBallers! We have a bigger slate on this Saturday evening for once. It is a nine-game slate on both sites for the MLB main slate. We have some heavy hitters on this slate, so let's dive in!
We have a few directions we can go on this slate, but per usual, Coors Field will be in play, especially with the Padres in town. We also have a couple of pitchers' duels in Minnesota and Kansas City.
This article will provide my daily fantasy baseball lineup picks for DraftKings and FanDuel on Saturday, 5/10/2025. The main slate starts at 7:05 p.m. EDT. The lineup picks will showcase elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for other sports here. Monitoring injury news and today's MLB starting lineups is always essential.
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DraftKings, FanDuel Pitchers - MLB DFS Lineup Picks
Joe Ryan - MIN - RHP ($9.6K DK; $10K FD)
Joe Ryan has had an up-and-down season, but he's kicked it into gear in the strikeout department. His SwStr% is up nearly a whole point from last season, at 13.4%. The Giants are in the middle of the pack when it comes to strikeouts, at 20.5%. Ryan has had 8+ Ks in three of his last four games. Outside of a five-run game against the Braves, he has only given up two runs in that same period.
I think a lot of people will be rostering Logan Webb, so going with Ryan might be a good way to get off some of the chalk.
Edward Cabrera- MIA - RHP ($7.3K DK; $7.8K FD)
Cabrera has had a rough start to the season as he has posted a 6.29 ERA on the season, but he does get a reasonable matchup against the White Sox. The White Sox have a 23% K% over the last two weeks and a below-average wRC+ in that time.
He hasn't quite gotten to a quality start, but has five+ innings in three of his five starts this season. He should have a chance here against a poor-hitting team in the White Sox. We are also getting Cabrera quite cheap, which should give us plenty of room elsewhere to spend up at.
Stephen Kolek - SD - RHP ($7.2K DK; $7.6K FD)
Stephen Kolek had a solid first outing, blanking the Pirates for no runs and only giving up four hits in almost six innings. He gets a magnificent matchup against the Rockies. Although it is in Colorado, the Rockies have been shut down by RHP over the last two weeks.
A really encouraging first start in the Major Leagues for Stephen Kolek:
5.1 IP
0 R
4 H
4 K
2 BB
84 pitches (51 strikes) pic.twitter.com/tUWp3we9yi— Sammy Levitt (@SammyLev) May 4, 2025
The Rockies hold the lowest wRC+ against RHP across the last two weeks. Kolek is still fresh, but he should be able to stop a struggling Rockies team from getting too many hits as he continues to fill in for the injured Yu Darvish.
Also Consider: Garrett Crochet vs. KC, Logan Webb vs. MIN
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DraftKings, FanDuel Infielders - MLB DFS Lineup Picks
Pete Alonso - NYM - 1B ($6K DK; $4.1K FD)
Alonso gets the benefit of the bullpen game against the Cubs here. They are starting against former starting pitcher Brad Keller. Alonso has mashed righties this season, where he has a .455 wOBA and a .650 SLG. He also leads the team in home runs against RHP with nine this season.
King of Queens 👑
Pete Alonso was mashing in March/April!
(MLB x @Chevrolet) pic.twitter.com/aGItFIKndm
— MLB Stats (@MLBStats) May 3, 2025
Cal Raleigh - SEA - C ($5.5K DK; $3.6K FD)
Cal Raleigh has been superb this season. He leads the league in home runs with 12 and has been crushing as a fantasy player recently. He has scored 9+ fantasy points in 10 of his last 11 games. Bowden Francis has declined over the last few games, and Seattle is hitting the ball well. Raleigh has posted a .473 wOBA and a .699 SLG against RHP this season.
Zach Neto - LAA - SS ($4.4K DK; $3.3K FD)
Zach Neto has been extremely productive in recent games. 19 hits in 13 games. He had a rough outing last night that ended his hitting streak, but he should be able to get back on track against Kyle Gibson, who was blown up in his season debut. Against RHP this season, he has a .398 wOBA and a .547 SLG, which leads this Angels team.
Also Consider: J.P. Crawford - SEA - SS ($3.6K DK; $2.9K FD), Vladimir Guerrero Jr. - TOR - 1B ($5.2K DK; $3.4K FD), Maikel Garcia- KC - 2B/OF (FanDuel Only)/3B ($4.5K DK; $3.2K FD)
DraftKings, FanDuel Outfielders - MLB DFS Lineup Picks
Jackson Merrill - SD - OF ($6.3K DK; $4.2K FD)
Jackson Merrill has been red hot since coming back from injury. He has scored 12.2, 28.2, and 22.2 in the three games back. He is crushing RHP this season with a .592 wOBA and a .810 SLG. On top of all that, he gets Coors Field and a poor pitcher in Bradley Blalock, who is sporting an 8.03 ERA on the season. Sign me up, this one is a given.
Julio Rodriguez - SEA - OF ($5K DK; $3.5K FD)
Julio Rodriguez has been quietly producing recently. He has 15 hits in his last 11 games and hasn't had a strikeout in seven games straight. His plate discipline is improving this season, and if he can continue to make better and better contact with the ball, he can be a dangerous hitter.
Rodriguez has a .328 wOBA and a .388 SLG against RHP this season, and after a slow start, we should see this begin to see those numbers increase.
Believe it or not, Julio Rodriguez is off to the best start of his young career. He is just one tweak away from taking off.
He's running the highest BB% of his career and the lowest SO%. His hard hit% is about what it's always been. He's accumulated 1.1 WAR, the first time he's… pic.twitter.com/hJ3x3Nnbwy— Mariner Mojo (@MojoMariner) May 3, 2025
Ryan O'Hearn - BAL - OF ($4.6K DK; $3K FD)
Ryan O'Hearn has been a bright spot for this Baltimore offense, which has struggled. Versus RHP, O'Hearn has hit very well against, as he has a wOBA of .471 and a SLG of .682. Jack Kochanowicz has been blown up by LHH this season. Hitters are hitting .416 wOBA and .590 SLG against him. O'Hearn makes for a solid one-off play or a Baltimore stack in some big GPPs.
Also Consider: Fernando Tatis Jr. - SD - OF ($6.5K DK; $4.5K FD), Juan Soto - NYM - OF ($5.3K DK; $3.9K FD), Daulton Varsho - TOR- OF ($4.3K DK; $2.9K FD)
DraftKings, FanDuel MLB DFS Stacks
San Diego Padres vs. Bradley Blalock - COL (Implied Run Total: 6.9)
The Padres are coming off a 13-run game here against Colorado, and now will get an even better matchup against Bradley Blalock. Blalock has been blown up in his first two starts, giving up nine runs in 9.1 innings. The Padres have been one of the best teams in the league this season and get the benefit of Coors Field.
Fave Combo - Merrill, Tatis, Machado, Sheets, Arraez
Seattle Mariners vs. Bowden Francis - TOR (Implied Run Total: 4.3)
Seattle has the highest wRC+ in the last two weeks at 148! I don't think that before the season, I would have been saying that sentence, but here we are. Bowden Francis has lost the plot as well as he has been blown up in his last three starts, giving up 14 runs in that time. As a team, they are hitting .372 wOBA and .466 SLG against RHP.
Francis' SwStr% is down significantly this season at 8.9% and has been crushed in the zone with a Z-Contact% of 88.4%. Seattle has been in the zone and should be able to continue to do that here against Francis.
Fave Combo - Raleigh, Crawford, Rodriguez, Polanco
New York Mets vs. Brad Keller - CHC (Implied Run Total: 5.1)
Brad Keller is opening for the Cubs in a bullpen game. This could either go well for them or extremely badly. The Mets have been crushing the ball right now, as they have the sixth highest wRC+ at 124 against RHP. Keller hasn't pitched more than two innings this season, but I imagine with his past, he will go longer for the Cubs.
Keller has been specifically crushed by LHH this season with a .424 wOBA and a .481 SLG. The Mets have a lefty-heavy lineup, too, that could take advantage of this.
Fave Combo - Soto, Alonso, Lindor, Nimmo, McNeil
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